Skip to main content

Euflexxa User Reviews & Ratings (Page 3)

Euflexxa has an average rating of 6.1 out of 10 from a total of 259 reviews on Drugs.com. 55% of reviewers reported a positive experience, while 35% reported a negative experience.

Reviews for Euflexxa

  • Grand...
  • Taken for less than 1 month
  • April 26, 2017

For Osteoarthritis "Osteoarthritis is part of my life in hips, shoulders, ankles, and most of all those knees. My knees are bone on bone and cortisone (not good for long term) is not long lasting. Noting the complications and side effects of total knee replacements, to say nothing of pain and rehab, I am not interested in giving up my golf and life for months. My Ortho Doc suggested Euflexxa a year ago and as a last resort, I agreed. I had my third week of injections yesterday and all I can say is that I have had a HUGE improvement. On a scale of 0-10, my pain was 9.9 and now I am at a minimal discomfort around a 3. Hoping it lasts for the full six months. It is wonderful to go up and down stairs forward rather than turning sideways."

9 / 10
Was this helpful?YesNo
45 Report
  • Alexa
  • October 19, 2019

For Osteoarthritis "I have osteoarthritis bone on bone both knees. The pain in the right knee is worse than the left. I had no relief from a cortisone injection. The right knee was injected with Euflexxa. About 72 hours post injection, I developed bruising and swelling in the area that was injected. I was nauseous, hot and sweaty, but had no fever. The knee was extremely painful, with increased swelling. Nothing relieved the pain. The doctor aspirated fluid, and sent it for analysis and sent me for blood work. Results were normal. My experience with Euflexxa has been a nightmare. I still have pain at night and cannot sleep, and there is a constant nagging pain in the the area where injected that is hard and extends upward a few inches. The doctor cannot tell me what happened. He has referred me to a surgeon to discuss knee replacement. I am thoroughly depressed over the entire experience not to mention the constant pain."

1 / 10
Was this helpful?YesNo
32 Report
  • Buddy
  • October 17, 2019

For Osteoarthritis "I had such high hopes that these Euflexxa injections would work for me. Did absolutely nothing but waste my time Tip! If you are going to get these injections I recommend that you go to someone who uses the guided ultrasound for proper placement of the injection site . If I had know this before I went to my doctor, I would have requested the guided ultrasound"

1 / 10
Was this helpful?YesNo
32 Report
  • vica
  • Taken for 5 to 10 years
  • August 4, 2018

For Osteoarthritis "I love Euflexxa! I've had 5 rounds of it over 5 years. Yes, I'm bone on bone, but still have a bit of space in my knee joint for the medication to get in and be useful. Since I've had 2 orthopods tell me that studies show that knee injections done blind only actually get in the joint space 2 out of 3 times (despite the claimed skill of the doctor in doing injections) I have the Euflexxa injected under floroscopy by a radiologist to be sure the medication goes to the correct space (my husband is a radiologist who suggested it this way if I wanted to be sure). Euflexxa is the difference between me being able to walk (limp) 20 feet in severe pain, and me being able to walk for long distances for many hours WITHOUT pain. I'm not ready for knee replacement mentally and this is a wonderful thing. I've never had any reaction and find pain subsides after the 2nd injection and lasts fully for 6 months and then I start hurting again and need another round at about 8 to 10 months out."

10 / 10
Was this helpful?YesNo
38 Report
  • Photo...
  • Taken for 2 to 5 years
  • April 18, 2019

For Osteoarthritis "I am 68 years old and have OA in both knees. I have been nearly bone to bone on the left side. Three years ago I had so much pain that it was difficult to walk, and could hardly stand. I work 8 hours per day on my feet, so my Dr suggested Euflexxa injections and I must say they were a MIRACLE for me! I have had them every 6 months in both knees for the past three years and I have always gotten great results and relief. I have been able to work daily and not miss any time off, as well as work in my yard, and chase the grandkids around. I just started another round, and I am having a lot of pain in left knee but right knee is responding as usual, however, it is feeling like I may be facing a knee replacement on the left side. If your insurance will cover this drug, it is WELL worth the investment. It has bought me several years of mobility and pain free, even though it may be replacement on the one. I will come back and give an update after series is complete."

10 / 10
Was this helpful?YesNo
34 Report

Are you taking this medicine?

  • Donuts
  • Taken for 1 to 6 months
  • September 15, 2019

For Osteoarthritis "I am an 81 yr old female and had a right total knee replacement 13 yrs ago. Began having increasing pain in left knee several months ago. Completed Euflexxa injections last week and have had a very good response. Occasional discomfort but mobility is much better and my quality of life is greatly improved as my goal is to remain as active as possible for as long as possible."

9 / 10
Was this helpful?YesNo
32 Report
  • Very...
  • Taken for less than 1 month
  • June 11, 2019

For Osteoarthritis "I am 66 years old, with bone-on-bone arthritis in my left knee. I had mild discomfort walking, and it took away my favorite activity, walking two or three miles a day. Euflexxa has worked great for me. I asked the doctor if I should return in six months for another series of injections, and he said not necessarily. He said for the patients Euflexxa works for, it tends to work very well and be long-lasting. And hopefully in a few years regenerated cartilage will make knee replacement surgery a thing of the past."

9 / 10
Was this helpful?YesNo
33 Report
  • AWF
  • February 21, 2017

For Osteoarthritis "I had Supartz injections several years ago with good results. When I moved, the new Dr said Euflexxa had fewer side effects. This was certainly not the case for me. I was in constant pain and almost a cripple for 6 months. I couldn't walk up stairs, or do most of my normal activities. I spent most days on the couch with bags of ice on both knees. Cortizone was useless. There appears to be no treatment for this side effect. I am an active person, of normal weight. Both knees are still swollen, but the pain is better than it was. I read that it could be another 6 months before I feel better. I wouldn't recommend this medication to anyone. It's not worth the risk of losing 6 months of your life that you'll never get back."

1 / 10
Was this helpful?YesNo
44 Report
  • Sue
  • Taken for less than 1 month
  • August 6, 2019

For Osteoarthritis "Finished up my 3 rounds euflexxa shots 2 weeks ago on both knees. Both knees have no cartilage but only one with severe arthritis (left.) Have had cortisone shots which first worked well (I am jogger). When the cortisone started wearing off after a shorter time, dr. recommended euflexxa. The injection was very painful and almost didn't go back. I shouldn't have gone back, for now, I can't even jog anymore. Before I could run with some pain but now it's unbearable. I am very active, exercising 5 days a week and now it's extremely difficult. I will never do this again."

3 / 10
Was this helpful?YesNo
32 Report
  • Deb
  • Taken for 1 to 6 months
  • October 14, 2019

For Osteoarthritis "Thin 55 y/o runner with bone on bone osteoarthritis and lots of pain. Decided to do the 3 injections of Euflexxa. Doctor did the first 2 and had minimal problems with little pain and a NP did the last with out the sonogram for placement of the injection and it was a very painful experience and I have not been able to walk since then. It’s been 2 weeks and I’m hoping it gets better soon. Upset that I let the NP do the injection. Given my experience I will not be doing this again. As mentioned before by others many times, not worth the time & expense. I hope to get back to where I was before the treatment. I’m in a great deal of pain with lots of difficulty walking. Really bummed for I travel a lot and have great difficulty walking now."

Was this helpful?YesNo
31 Report
  • Carter
  • May 20, 2014

For Osteoarthritis "1st shot I had started relieving my pain of going from sitting to standing. Had 2nd shot yesterday, sitting icing it now. My trainer is due in an hr so we will do upper body only which is what the ortho said for the day after a shot. I had a torn meniscus repair in December 2013 and my pain started again in March, I thought I had torn it again but he said nope, bone on bone. So far so good on this and I am 62. I am active with my personal trainer 3 times a week for the past 1.5yrs and I can't wait to be 100% active again."

9 / 10
Was this helpful?YesNo
56 Report
  • person
  • April 2, 2021

For Osteoarthritis "This works for me-usually between 8 to 12 months. Relief has been quick-even after the first injection. I have had this (I think) 5 times. My knee is never perfect, but it significantly delays the inevitable progression of knee fixes---surgery to clean it up, knee replacement, etc. I started when I was 45 years old as bad knees run in the family. The injections can be somewhat painful and some are very painful--for a few moments at least. It is hard to voluntarily go in knowing it might be intense. BUT--- I can walk around and live a fairly normal life by suffering a bit. Well worth it. I'd be in a wheelchair without these things-so I can't complain."

10 / 10
Was this helpful?YesNo
23 Report
  • Jasper
  • December 5, 2015

For Osteoarthritis "I've had 3 series of Euflexxa with good relief from bone on bone pain as long as I don't overdo. They make it easier to walk and reduce general pain and stiffness. They also help significulty with preventing my knee from going into a sublux position. The injections themselves aren't painful, just uncomfortable. My doctor uses a topical anesthetic and is very gentle. Any pain is brief. I have some very minimal bleeding and swelling at the injection site and take it easy afterward. I'm so grateful for Euflexxa. I received injections of Synvisc (similar but with actual rooster comb as opposed to a synthetic) before. They worked great and I needed only 1 shot, not 3, but like many, I had a severe painful reaction with repeat injections."

9 / 10
Was this helpful?YesNo
48 Report
  • Patty...
  • Taken for 1 to 6 months
  • July 15, 2014

For Osteoarthritis "I am 49 and my right knee has been hurting for a year. MRI showed no tears, just worn cartilage. Steriod shot gave immediate 100% relief from pain but only for 2 1/2 months. Dr. gave me the series of Euflexa shots and the shots were not painful...just a little uncomfortable. But I have had very little relief from pain. I am having to take anti-inflammatory and pain pills but still not much relief. Scared Dr. Is going to have to scope it. "

2 / 10
Was this helpful?YesNo
53 Report
  • Tooyo...
  • Taken for less than 1 month
  • January 22, 2015

For Osteoarthritis "Had first shots in both knees 5 days ago. Almost instant relief. Not 100% but a very noticeable difference just leaving the drs. Office. Also have a recent meniscus tear that the Dr. wanted to wait on and see if these shots helped. Staying hydrated before the injections helped the shot pain. A little cold spray and it was almost painless. The only reason I didn't give it a ten is because I don't know the long term effects."

9 / 10
Was this helpful?YesNo
50 Report
  • Old...
  • Taken for 2 to 5 years
  • September 22, 2017

For Osteoarthritis "I am 71 yrs old with bone on bone severe arthritis in right knee and arthritis left knee. Orthopedic surgeon suggested knee replacement three yrs ago. Started euflexxa injections at that time and now relatively pain free. Have the three shot treatment every 6 months. I walk 2 miles daily, do Zumba and strength training. Hopefully, I will never need knee replacement."

Was this helpful?YesNo
38 Report
  • TX277
  • Taken for less than 1 month
  • March 12, 2017

For Osteoarthritis "I'M 57 yrs old and suffer from moderate bilateral knee O/A. In Oct '16, I had to stop taking Cerebrex due to GI complications to NSAIDs. So, I opted to take Euflexxa injections for my knee pain instead of steroid shots due to a more "natural" treatment. Two Wednesdays ago, I had my first of Euflexxa shots, but the side effects were awful (unbearable knee pain for 4 days, chronic pain for 3 days, joint pressure). I searched on the Internet and found numerous reviews of people that experienced similar side effects. So this past Wednesday at my appt for the second set of Euflexxa shots, I explained my experience to the doctor and refused to continue the treatment. Euflexxa didn't work for me and left me more achy and very dissapointed."

Was this helpful?YesNo
40 Report
  • Chef...
  • Taken for less than 1 month
  • September 28, 2019

For Osteoarthritis "This past Monday was my last shot of "the gel". When I did the first shot they removed 4 syringe of fluid from my knee before they could inject the gel, by the third injection almost no fluid but for me it has not been a quick pain reliever, the side of my knee still hurts. feels like someone is stabbing you will a sharp object, for example it is difficult to press on a car brake, it is stiff when I sit down and painful when I get up. They said it will take 7-8 weeks to have the gel take affect. I hope so."

7 / 10
Was this helpful?YesNo
28 Report
  • sarome
  • September 22, 2015

For Osteoarthritis "I had a torn PCL, and developed early arthritis on my right knee. Very painful, Swollen, could not bend my knee, can't bear weight on that knee. Had 3 shots of Euflexia in October of last year, since then, I have been pain free. No swelling. The drug is good."

10 / 10
Was this helpful?YesNo
45 Report
  • Rich
  • February 6, 2020

For Osteoarthritis "I received first injection of Euflexxa only yesterday. I am in excruciating pain radiating down to ankle. I can walk without pain now. I am hopeful but if this doesn't subside I am in trouble. 51 yo avid skier, hiker, biker and I am stuck on couch. I will update but as of now very nervous this has made things worse"

1 / 10
Was this helpful?YesNo
26 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • May 19, 2012

For Osteoarthritis "Had first series 6 months ago and had to wait the full six weeks for relief. I would say that the pain subsided at that point but not completely. I have just completed my second series six months later and the relief was immediate and complete. I am pain free! Had some headaches at the back of my head but nothing bad enough that I would not continue with this life changing experience."

10 / 10
Was this helpful?YesNo
56 Report
  • Tmoney
  • June 22, 2017

For Osteoarthritis "Had my last of three injections in my left knee on June 2, 2017. I had about a week of minimal pain and some return of movement. Today, June 21, 2017, the pain is about twice as bad as before the injections and my knee is swelled up so bad it's hard to put on jeans. The swelling has also moved down to my ankle. My left ankle is twice the size of my right ankle. My doctor told me to come back in 6 weeks for a cortisone "booster" if I still felt pain. If I might need a "booster", why was this expensive trash recommended in the first place?"

1 / 10
Was this helpful?YesNo
37 Report
  • Marj
  • Taken for 10 years or more
  • September 19, 2019

For Osteoarthritis "These injections allowed me to postpone knee surgery for 10 years. They worked great! I was able to continue hiking up hills and taking long walks with no pain whatsoever. They lasted about a year or so each. Towards the end they stopped working entirely and I had to have knee replacement surgery."

10 / 10
Was this helpful?YesNo
27 Report
  • Vic...
  • October 10, 2015

For Osteoarthritis "I started using Euflexxa several years ago while training for a half marathon. Having a previous meniscus tear, I wanted to err on the safe side for the training, especially being in my 60's and overweight. About a year ago, I experienced another meniscus tear and recovery was difficult at best. It was to the point I was begging the Dr. for a new replacement. A second opinion confirmed I was definitely a candidate. I toughed it out. Therapy, exercise, losing 40 pounds, continuous stretching, massages have paid off. Even though I limp a little and stiff in the morning, replacement is off the radar. I'm now going back for more injections before the end of the year. They are a little pricey but definitely cheaper than a knee replacement."

10 / 10
Was this helpful?YesNo
42 Report
  • Rae
  • January 21, 2019

For Osteoarthritis "I’m 41 year old with bone on bone osteoporosis in both knees. Dr says my knees look like someone’s twice my age. I had the series of 3 Euflexxa injections in my right knee. They were pretty painful injections. The third being the most painful. But, here it is almost 4 weeks since the last injection and I’m in a worse condition than pre injections. I was hoping these were going to work but I’m here to say they’re just a waste of time & money. I do not recommend these injections and I not go through the pain again for no result."

1 / 10
Was this helpful?YesNo
29 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.