The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Zoloft (sertraline) for Panic Disorder: Currently take 75 mg of Zoloft per day to help with panic attacks and anxiety (no depression). Took about 1 month for my panic attacks to totally stop. Still had anxiety but now that I've been on it for almost 3 months I have almost NO anxiety. Did experience a side effect of my jaw clenching starting in the 2nd month. When I was on 100 mg (my doctor didn't believe this was a side effect of the medicines (but I am CERTAIN), so I backed myself down to 75 mg and after 2 weeks of being on that reduced dosage the jaw clenching went away. SO grateful for this medicine. VERY IMPORTANT- if you have anxiety, panic, or depression. GET COUNSELING- it helps almost as much as the medicine.
46 users found this comment helpful.
Zoloft (sertraline) for Depression: I started Zoloft just two months ago. I had been depressed for nearly two years. It got to the point of planning a suicide. I decided to go get help and give life one more shot. The doctor prescribed Zoloft to me and it has made all the difference. I really started noticing a change after the first month. There's a complete change in my attitude and outlook on life. It may have saved my life.
35 users found this comment helpful.
Zoloft (sertraline) for Depression: When I started taking Zoloft I lost 40 pounds in three months which was GREAT. My depression got better, anxiety was better. I did lose my sex drive but who cares, my self esteem was GREAT. Zoloft saved me.
83 users found this comment helpful.
Zoloft (sertraline) for Depression: I started taking this medicine when I was 16. I am 26 now. Right now I take 100mgs. I was an unhappy teenager and I can't say it did anything for me at that point in my life (but I was only taking 50mgs then). I stayed on Zoloft all through college and only went off of it for about 6 months, at the urging of a boyfriend at the time. Those months were bad. I tried everything to feel better (exercise, meditation, different activities) but I always felt like there was blackness hanging over everything. I couldn't function socially and became rather reclusive. With the help of my therapist and psychiatrist, I went back on Zoloft and my depressive symptoms decreased dramatically. I have been on Zoloft for 10 years now so it's just a part of my life. I get sad sometimes, but when I get hopeless feelings I can process them more easily. It's hard for me to imagine life without Zoloft, but I hope to someday regulate my depression with a therapist and go off of it. That said, I don't really have any side-effects to speak of. Sometimes I have a low sex drive, but its only at certain times of the month, like before my period. However, having a diminished sex drive on antidepressants is easier than not having any drive whatsoever when you are off them. To me, taking Zoloft is almost like taking a vitamin. It's no big deal.
36 users found this comment helpful.
Zoloft (sertraline) for Depression: I was just prescribed this medication for GAD and Moderate Depression. My Doctor suggested 25mg once a night. I accidentally took 50mg the very first dose but I feel fine. It took me a little while to fall asleep last night and I feel a bit drowsy but I am writing this from work so obviously I'm still functioning normally. I realize that Zoloft will affect everyone differently and I am very nervous/excited about its potential to help me. I'm hoping that in time I will feel less tired. I take Vitamin B 12 shots every few weeks so that should help too. I've never taken any prescriptions before now so I was very nervous about this whole thing. The reviews have been helpful though, I wish you all the very best of luck with your treatments.
26 users found this comment helpful.
Zoloft (sertraline) for Post Traumatic Stress Disorder: I have had PTSD for 15 years, I was skeptical about taking medication for my condition, thinking each day I would fight on and get better without the aid of medications.
I have finally sought help and have only been taking Zoloft for a short period of time and already I feel the difference. I feel happier and my general mood is more positive, the negative thoughts have diminished considerably. I have had no bad side effects to date. My advice to anyone hesitating is just pluck up the courage and talk to your doctor.
51 users found this comment helpful.
Zoloft (sertraline) for Bipolar Disorder: I took Zoloft for 2 years at 100mg daily for bipolar disorder type I. Zoloft is wonderful in that it made me significantly less anxious. However, it didn't succeed in making me any less depressed. Also, as with most anti-depressants, I experienced a decreased sex drive.
Zoloft (sertraline) for Depression: I've been taking Zoloft for about a week now and its made me nervous, dizzy, almost emotionally dead (though that might be because of the Depakote) and has really increased my psychosis to the point of where as an addition to hearing voices I have been hearing music when there should not be any music, oh and dry mouth. I'm going to give it some more time but if these symptoms continue I will stop. I've read a lot of positive reviews though and I don't react well towards many medication.
Zoloft (sertraline) for Obsessive Compulsive Disorder: Got diagnosed with Obsessive Compulsive Disorder in February of 2011. Started taking Zoloft at 50mg in the morning on April 8 (1 week ago) and my oh my what a difference! The depression is lifting significantly! - I'd say it has gone from a 2 to about a 7 in just a week's time. The intrusive/obsessive thoughts have dropped about 75-80%, the compulsions are all but gone and the general anxiety is all but gone. The next to go are the annoying ruminating thoughts and the difficulty concentrating and organizing thoughts (but since I've been so depressed for so long, I think those parts of my brain had forgotten how to function). Starting tomorrow I kick it up to 100mg a day. Hoping for the continued improvement.
42 users found this comment helpful.
Zoloft (sertraline) for Anxiety and Stress: I had horrible anxiety attacks last fall, to the point that I thought I would just rather die then have a life like that. It took me over 2 months to try Zoloft, and it was the best decision I ever made. The first week was filled with an even higher level of anxiety, but it didn't last throughout the day, and in the evening I started to feel normal. After about 2 to 3 weeks, I was completely back to normal, and I was upped to 100mg/day. I don't think I needed quite that much, but I followed doctors orders from 25 to 50 to 100 in the 3 weeks time. I am now taking 50mg every other day, (because I'm feeling so good, I keep forgetting to take it). It's been over 6 months, and I feel fantastic.
38 users found this comment helpful.
Zoloft (sertraline) for Anxiety and Stress: I've been taking Zoloft for a little over a year. It has been very effective for controlling my symptoms (I have GAD). Now I'm able to concentrate on my college classes, and in general stopped feeling anxious about different events and situations (exams, trips far away, driving a car, etc).
I started with 12.5mg and took that each morning for 6 months or so, without side effects. Then it stopped working well (the minor, yet bothersome, anxiety episodes came back), so I increased the dose to 25mg, and now am on 37.5mg, and doing good so far.
Usually, I am sensitive to medications, so it was a nice surprise that Zoloft did not affect me negatively. Thanks to Zoloft, I feel like a different, more confident and more calm person now.
24 users found this comment helpful.
Zoloft (sertraline) for Depression: I wanted to share my experience with Zoloft because I came to this website looking for reviews when I first started. I had my doubts at first, my doctor started me out slow at 50mg. Now I am up to 150mg. It has taken a good 5 weeks for me to finally feel a change. I actually woke up in a good mood the past few days. Let me tell you I spent a lot of days staying in my sweats all day watching TV thinking I was never going to feel better. For me it just took a really long time to take effect. The only side effect I have had is in the bedroom dept. Takes FOREVER if at all to have any fireworks go off for me, which was never a problem. Its really weird, but other than that no other side effects. I hope to feel even better each day.
30 users found this comment helpful.
Zoloft (sertraline) for Anxiety and Stress: I've been taking Zoloft 100mg for about 6 months now, it really has changed my life. Before medication, I wasn't leaving the house, had very little social contact and my anxiety was through the roof. Zoloft has been amazing for me, my mood has improved and I'm getting out of the house and keeping in touch with friends and family. I still have my bad days and also feel groggy most mornings but other than that I've had great results while taking Zoloft.
15 users found this comment helpful.
Zoloft (sertraline) for Bipolar Disorder: I was originally prescribed Zoloft for depression, but in 6 months I had a severe manic episode and was diagnosed Bipolar 1. Now I take Zoloft with other medicines. I would not recommend taking it alone if you may be Bipolar. I like that I have very few side effects and it does help with anxiety and compulsive behavior too. One problem is no sexual desire, I feel like I am neglecting my boyfriend.
Zoloft (sertraline) for Depression: The first week was rough, but this medicine has totally changed my life. I'm confident, I go out and do things. Life is enjoyable and I feel optimistic about the future. No more random panic attacks or feelings of worthlessness. Sometimes people say I'm too easy going but I can be serious when needed; basically I'm in control again. Been on it for 4 years (50mg daily) and may never go off it. Have noticed some weight gain and hot flashes in extremely stressful/confrontational situations.
29 users found this comment helpful.
Zoloft (sertraline) for Depression: I have been suffering from depression for 22 years. I am 41. Zoloft has helped me tremendously. I was always angry, tired, frustrated and had a hard time getting out of bed. With Zoloft I'm more sociable, friendlier and appreciative of the things that seemed insignificant. Every story is different, try it for yourself.
30 users found this comment helpful.
Zoloft (sertraline) for Depression: I have depression and anxiety, lately more depression, from being 40, with kids, uncomfortable marriage. Lexapro has suppressed things but I had become unemotional. On 50mg for a week now of Zoloft and the difference is incredible! I have reasonable emotions, and more energy to want to do the things I planned on but didn't do before. Sleeping is off and on a problem, has always been, but dreams are waking me up for being so vivid. Appetite is down, I'm glad. I had been steadily gaining weight because I didn't want to do anything, but now stomach is bad and I'm scared to go anywhere. Hoping that will go away. Can't say much about sex, not having any.
21 users found this comment helpful.
Zoloft (sertraline) for Anxiety and Stress: This pill has changed my life. I remember having anxiety and panic attacks in elementary school. My parents never felt that it was necessary to take me to the doctor but in college I started having bad panic attacks before and during exams. My anxiety really started affecting my life. I went to counseling and a stress therapist but Zoloft is really what has helped the most. I have noticed that it makes me sleepy during the day, even though I do take it at night. And I'm not completely certain but I think that it has caused a little weight loss since I have taken it for the last two months. Overall I would say that this medicine has more benefits than negative side effects. Thank you.
16 users found this comment helpful.
Zoloft (sertraline) for Depression: I started Zoloft before my 3rd child was born. I've had depression throughout my life and a major breakdown after my 1st child's birth. Noticed an improvement within days, and husband noticed huge diff. Dry mouth and increased appetite has cycled through the years on occasion. But the big side effect for me was insomnia. I thought it was my little one getting me up every 2 hours, but realized that taking the medicine at night was the cause. Switching to morning dose made such a difference. I do notice I don't sleep well if I take it after noon or 1pm. Some family members had tried it with no success. Give dosage and timing a chance. It has literally saved my life. I still feel emotional at times, but can cope with issues and heaviness in life has eased.
18 users found this comment helpful.
Zoloft (sertraline) for Anxiety and Stress: I was switched from Lexapro to Zoloft 50mg about a week ago and I found it quite helpful for calming my mind from obsessive thoughts and depressed feeling. Now I am on 75 mg and it is further improving my condition. After 1 week, I will be on 100 mg and I am hoping that it will give me more good results.
10 users found this comment helpful.
Zoloft (sertraline) for Obsessive Compulsive Disorder: I've been taking zoloft for a few years for ocd, starting with 20 milligrams per day and increasing to 40. It has helped me greatly with my obsessions, but not my compulsions. Of the two, I have always thought the obsessions were worse, so I think it has been a successful medicine for me. And so far, I have experienced no side effects. I also take zocor for cholesterol and have had no negative interaction.
14 users found this comment helpful.
Zoloft (sertraline) for Anxiety and Stress: I've taken 50 mg Zoloft for almost 2 years for anxiety. I love Zoloft and am so grateful for the mental freedom that it has given me. Since I have been on it I have been much, MUCH happier. Recently, I decided that I am finally ready to embark on a healthier lifestyle. I started working out religiously 5-6 hrs/week, a combination of weight training and cardio, along with calorie monitoring of 1200-1500/day. I have been unable to lose hardly any weight. I've lost 5 lbs total I am wondering if it is because of the Zoloft? I am now weening myself off of it to see if I am able to maintain a happy disposition. I'm hoping that I succeed in controlling my anxiety on my own & will be interested to see if the weight starts coming off.
Zoloft (sertraline) for Post Traumatic Stress Disorder: Well I've been off and on of zoloft and when I'm taking it my friends notice a very big difference. They say that I'm always a lot happier and more of a go getter. I just wish I would of been using it when my ex-fiancee was living here with me because well we'd probably still be getting married. As for side effect's I haven't seen really any at all, I still have a very high sex drive, I still eat like normal, and I'm a lot happier during high stress situations being in the military. But I've been taking 25mg a day in the morning and it help's tremendously. But like people say on here you just have to take it and see if it's for you or not. Hope this review helps everyone out.
54 users found this comment helpful.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Data sources include Micromedex™ (updated Dec 30th, 2013), Cerner Multum™ (updated Jan 17th, 2014), Wolters Kluwer™ (updated Mar 2nd, 2014) and others. To view content sources and attributions, refer to our editorial policy.