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Compare all 101 medications used in the treatment of Depression.
Reviews for Zoloft to treat Depression
Review by kookalinMD:
Started taking 100mg one year ago for mild post partum depression. It really helped me for the first 6(ish) months and I definitely felt a change. I started feeling depressed again (several life "happenings") so my doctor increased my dose to 150mg, which I have currently been taking for going on 4 months now. I've been feeling depressed again and am at the point where I either need to increase my dose (again...and I'm already on a high dose) or switch to a different medicine. I think I'm trying the latter. Some of the side effects I have experienced:
insomnia, extreme fatigue, slight weight gain (10 lbs over a one year period...active young mom, so very weird for me), increased depression, headaches.
21 users found this comment helpful.
I was prescribed Zoloft for depression. I had tried Wellbutrin and Lexapro in the past with little results. With Zoloft at first the side-effects were tough. Also, I was having sexual side-effects. Lacking desire (which is not normal for me), and the inability to achieve orgasm. I decided to try taking my pills in the morning, rather than at night like I had been doing. After a couple of days past on with my new schedule, the sexual side effects subsided and I'm back to normal with that. I never knew an anti-depressant could help so much, but it has REALLY helped me!
176 users found this comment helpful.
Overall, Zoloft is a good drug. I have taken it for a few years now and have had no side effects. It helps with my depression, but still struggle with an occasional panic attack. I am on a higher dose than most people, 100 mg, and might have to go higher or switch to something else, I would recommend it for mild anxiety and depression
38 users found this comment helpful.
I started taking this because I was getting upset really easy. At first I felt a little happier but it definitely made me shaky and sick. I get upset a lot less but I'm really just numb to everything. It make me impulsive and irritated.
31 users found this comment helpful.
Helped with my mood really well.
But I had severe tremor which I had to endure for a month before it could be stopped. The tremor did not ease at all, it even made my feet shake when they were off the floor and my jaw. If you can put up with tremor it definitely helps with lifting your mood!
10 users found this comment helpful.
I started taking Zoloft about 3 1/2 weeks ago. The first week I started to feel better. Though about 5 days in I had a really bad hotflash where I had to lay on the floor for about 5 minutes, and then I felt like I was going to throw up. Haven't had that sense. I do feel tired so I've started taking it at night. Also, I feel like I have restless leg syndrome. But other than those things I am now able to focus and my OCD seems to have calmed down a lot. I still get anxious, but it doesn't stick around as long and I'm able to move on from it easier. I feel like I can live in the moment and not worry about my past or present or what issue I need to stop before it happens. I am able to focus better at work too. I think my husband likes me now.
253 users found this comment helpful.
I was on Zoloft for 8 years. Most of those on a minimum maintenance dose. In the last few years it affected my memory and it didn't work as well for the depression and anxiety. Does a good job treating PMS. I had to go off eventually, but it was a good run. Had night sweats and some sexual side effects. I also would feel nauseous if I was hungry while I was on it. Best to take at night.
34 users found this comment helpful.
Zoloft is not a good medicine for "severe" depression. I have OCD and that is what this medicine is best used for. It does help with the anxiety and the headaches that go along with it. It keeps the obsessive thoughts to a minimum. My compulsive need to make everything perfect is also gone. It makes you more social too. It has not made me gain weight. It is a good drug if used for OCD.
56 users found this comment helpful.
I was put on Zoloft for Major Depression and General Anxiety Disorder after my baby was born about a year ago. In general, it helped with my mood swings not being so intense, but I also found, over time, that it did not help me in stressful situations and I actually was more aggressive while taking Zoloft. I have also gained weight on this medication and am now 30lbs over my average weight. Some other side-effects have been dry mouth, anxiety in the mornings, more agitation, and an increase in anxiety-soothing habits (such as picking, scratching, obsessing over flaws, etc). After taking Zoloft for a year, I've found that it's not really helping with my depression or especially my anxiety anymore.
30 users found this comment helpful.
From first week when I took this medicine I can feel a slight change and haven't felt depression, anxiety. But as the weeks pass, I felt much better. I've got my life back, social skills, and feel like everyone else. This drug has really helped to bring my life back.
214 users found this comment helpful.
I took this medication for about 3 months and it did relieve my severe depression but the side effects became unbearable for me and I had to change to another SSRI. This medicine caused headaches, salty dry mouth, insomnia, muscle twitching, nausea, dizziness and a feeling of emptiness.
29 users found this comment helpful.
Zoloft is great it really has helped me with depression and anxiety. I have chronic obstructive pulmonary disease and getting depressed and upset triggered severe asthma attacks. I take 100mgs twice a day. It has really been a blessing. Don't listen to any of us, every person is different try it and see what it does for you, then you and your Doctor can decide the proper treatment for you.
182 users found this comment helpful.
No suicide ideation, but I was the most boring, apathetic and tired person ever. I literally fell asleep standing up. Extreme dreams. This changed me and everybody noticed. It was only good in the sense that I was no longer sad.
28 users found this comment helpful.
I have been taking Zoloft for two weeks now and feel remarkably better. Very mellow. I am also sleeping much better and waking more refreshed. In conjunction with the Zoloft, I was also prescribed Clorazepate. This combination is working very well for me. I have even had a few giddy moments and that has not happened in a very long time.
34 users found this comment helpful.
I was very depressed during and after my pregnancy. Finally I found a good doctor and she prescribed Zoloft. I felt the difference from the beginning. I had some side effects but nothing major, however the only complaint I have is the weight gain. I take 25mg daily, a very low dose but I am getting very heavy. I've been taking Zoloft for almost 2 years and feel okay but not cured.
15 users found this comment helpful.
I've been on Zoloft for almost a year now. I will be changing medicines in 4 days, which makes me really anxious. This drug worked well for my depression and anxiety. However, I've been completely unable to have a good time while on this medication. I can't bring myself to go out, hang out with friends. I do nothing. I have no motivation. The biggest problem I've had with Zoloft is extreme weight gain. I've gained 50 lbs in the year.
130 users found this comment helpful.
I was taking 50mg of Zoloft a day for two months and it made me even more irritable and down. I didn't want to do anything. When I did force myself to go out and socialize I'd snap at people. Nothing was fun. Nothing seemed to be worth doing. I've tried both Lexapro and Zoloft. Neither have made me feel any better. I got worse on both. I don't always want to feel depressed, but at least off of medication I have the ability to hide my feelings from people, not to place other people under the weight of my moods, but on those two medications I didn't even feel like I had the power to fake it. Zoloft also gave me migraines, ones that would last for a week straight. Glad it works for some people though.
107 users found this comment helpful.
I was crying over the weirdest things and didn't want to get out of bed. Then I started taking Zoloft 50mg daily, a month ago. I felt relief an hour after taking it. The side effects for me were stomach upset, decrease in appetite, and sleepiness. That only lasted a week. After three weeks I increased the dose to 100mg which my doctor suggested in the beginning. I have been on many different antidepressants since I was a teenager and this is the first one that I feel "normal" on. I don't feel emotionless or stay on a fake happiness high. I feel relieved and can deal with the day to day stresses.
355 users found this comment helpful.
I started Zoloft two days ago. Literally after an hour of taking half of a 100mg tablet I could feel the effects. Everything just felt crisp and bright and I felt alive for the first time in years. I was worried my emotions would be just the same the whole time but I saw a very sad movie this morning and was able to cry, just like I normally would.
i had mild teeth grinding at night and awoke in the middle of the night and couldn't sleep for a few hours but other than that i'd recomend zoloft to anyone.
69 users found this comment helpful.
I started on 50mg of Zoloft around 8 or 9 months ago, and it helped me a lot. Recently I went and got my dosage upped to a 100mg due to a few traumatic things, I became very, very depressed. That was about three months ago and I feel a lot better, not 100% but better none the less. I never really noticed any side effects, except gritting my teeth at night, and I do think it makes me a little drowsy. As far as sexual side effects I've had none, unlike the previous two medications I tried.
44 users found this comment helpful.
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