Skip to Content

User Reviews for Sertraline

Also known as: Zoloft

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Sertraline.

Ratings Summary

Filter by:

User Ratings

10
   
25%(107)
9
   
24%(102)
8
   
16%(69)
7
   
12%(50)
6
   
7%(29)
5
   
5%(18)
4
   
3%(13)
3
   
5%(19)
2
   
3%(11)
1
   
6%(25)

Sertraline Review Summary

7.5/10 Average Rating

443 Ratings with 377 User Reviews

What next?Compare all 134 medications used in the treatment of Depression.

Reviews for Sertraline to treat Depression

Sort by:

Zoloft (sertraline): "I was crippled with anxiety, depression, and nagging intrusive thoughts. Zoloft has allowed me to live again. Please don't allow the stigma and misinformation out there about antidepressants prevent you from getting help and finding relief. Once your body adjusts to Zoloft (this can take upwards of 2-4 weeks), you will find relief and peace. I used a pill cutter to cut the prescribed dose (25 mg) in half and took the half dose for two weeks. Then I increased it to the prescribed dose. This is much easier on the body. Please consider doing this so you're not overcome and discouraged by some of the initial side effects. Good luck friends."

   
10

SilvaMine May 26, 2015

4 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "Been taking 25mg zoloft for 2 weeks. Due to non stop over thinking, paranoia and constant checking up on suspected cheating partner. This drug has enabled me to think clearly again and be able to end an unhappy relationship that I could not end before. I don't react or panic at the thought of being on my own anymore. Its great to feel balanced and even keeled with my thoughts. No real side effects, although I am more motivated at home and don't seem to have a huge appetite so lost some weight. I like this drug, its given me some sanity again however I am worried about the symptoms returning if I stop taking it."

   
7.0

jillyangus May 23, 2015

8 users found this comment helpful. Did you?   Yes   No Report as inappropriate

"I started on 50mg. I felt better in 2-3 weeks. I was so happy to not be crying. I get dizziness and have the yawning effect. At first it seemed like I would yawn every 2 minutes for days. The only thing that upset me about it was that I gained weight. I'm already a bit on the heavy side, but I had been maintaining my weight for years. All of a sudden I gained about 25 lbs in 6 months. When I talked to my Dr, he said the dosage wasn't high enough, that I was emotionally eating. It didn't make sense to me, since I had been able to maintain my weight even during my depression. Anyway, he upped it to 100mg. Now, I just feel lazy. I don't care about getting things done. I have to really make an effort to do anything. I'm going back to 50mg."

   
7.0

rem1105 (taken for 6 months to 1 year) May 22, 2015

3 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "Absolutely changed my life. I am a 20 year old female who has struggled with depression and irritability since roughly 13. I tried meditation, I tried the "power of positive thinking", I tried listening to podcasts, I tried counseling. Nothing helped me until zoloft. I've been taking zoloft for 5 weeks. I had minor side affects for the first couple days (looser stool, headaches, stomach aches) but nothing I couldn't handle and they went away after 2-3 days as I got used to the medication. I'm currently taking 50 mg and don't plan on increasing. I feel overall happier. I'm not as irritable and things that I used to hate (going to work) are no longer even bad. I feel more myself, and like I'm not afraid to be outgoing. Highly recommended"

   
10

B.A May 22, 2015

10 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "This has been a life changer for me. I guess I never realized how depressed I actually was until I started on Zoloft. I'd been fighting it for years, forcing myself to get up and get by each day, but getting worse and worse (avoiding people, having problems talking, having horrible insomnia). Within a week of being on Zoloft I noticed a major difference. I actually feel optimistic about life for the first time in as long as I can remember. My relationships with my wife, family, friends, and coworkers have all improved dramatically. In short, I'm no longer depressed. I had some side effects over the first few days (restless legs, night sweats, a zonked out 'zombie' feeling) but they passed quickly."

   
10

HardLifeGuy (taken for 1 to 6 months) May 19, 2015

12 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "I just got back on it but use to take it for years and I was happiest when on Zoloft."

   
10

Tonton1965 (taken for 2 to 5 years) May 18, 2015

8 users found this comment helpful. Did you?   Yes   No Report as inappropriate

"When I first started taking this I was feeling great. Maybe a little too great! Everything just seemed amazing and I was so happy. I was previously taking citalopram which made me feel worse than I did before taking medication. Almost unbearable. So starting sertraline made me feel like there was actually something to make me feel better and that I can be positive again. But into my the 3rd week that kind of stopped and I was feeling less satisfied with life again. Very tired all the time. Some days feeling so sorry for myself I wanted to be alone and cry etc. Other days I felt so numb I didn't feel anything. I wasn't sad, wasn't happy, I just didn't care. still like this now after being upped to 75mg. Did anyone have this? Do I need upped?"

   
7.0

Rebecca rose (taken for 1 to 6 months) May 17, 2015

2 users found this comment helpful. Did you?   Yes   No Report as inappropriate

"I began sertraline 50 mg approximately four weeks ago. I wasn%u2019t sure weather to take it at night or in the morning so I experimented with both. I found that during the day I would become very lethargic and yawn constantly with little energy but would then wake up in the middle of the night stimulated regardless of the time I took it. This frustrated me as I have always had a good sleep schedule and am an active person during the day, but I had read that others had experienced similar side effects and the effects eventually ceased. I felt better for several days%u2014not as downcast, brooding, heavy. After three weeks of taking it, the effect seemed to even out and I found myself struggling with feelings of hopelessness and doubt again. I felt better, certainly, just still struggling%u2014I don't expect a pill to %u201Ccure%u201D me of negative thoughts. I know I have control over my own thoughts, but it was that feeling of heaviness that tends to settle upon me%u2014like a dark cloud. When I went back to my doctor for the follow up, he increased it to 100 mg. I said let%u2019s try 75 mg first. He agreed. Within a couple weeks of taking 75 mg I still yawned a lot but I wasn%u2019t having trouble with lethargy and sleep issues as much. My attitude was much better. For example, I found that I really am a funny and silly person! I forgot that I was funny being under depression. I didn%u2019t realize how serious I had become, how reclusive. I also found my creativity really opened up. I had forgotten how creative I was. I also have been going to the gym and eating well. I try and smile and interact with people more%u2014even if I don%u2019t feel like it. I may just greet people or hold the door for them but it%u2019s better than me avoiding people like I used to. Some days are harder than others, but I can say that overall my experience with sertraline has been positive."

   
8.0

Barnabas777 May 13, 2015

5 users found this comment helpful. Did you?   Yes   No Report as inappropriate

"I started on 10mg off citalopram when I was 16, they had zero effect so they upped me to 20mg of fluoxetine which made my severe depression worse, my brother was also prescribed fluoxetine and we both experience and major increase in suicidal thoughts whilst on them so I went back to the doctor. He then prescribed me with sertraline 50mg. The first few weeks of taking them were a nightmare, I'd wake up and take the tablet with my breakfast and I'd finds myelf being exhausted all then time and then I'd struggle to sleep at night. My partners mum is on sertraline 100mg and she said that the best thing to do is take them half an hour before you go to bed because the tiredness effect doesn't take long to kick in. Now I feel a lot happier"

   
8.0

Abbeyalp May 13, 2015

2 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "Hi I thought I would share my experience to help others make a good decision. 5 years ago I was diagnosed with a Panic Disorder, GAD, and Depression. My initial struggles ended up with me on Celexa. This drug did work but took a long time for to take effect. (4 months). Last September it finally just stopped working. I went through a major period of depression and withdrawls until I finally found Zoloft. I had immediate effects! It turned my life around I now have zero side effects. I do have some lingering anxiety but nothing I cant handle. Occasionally I take a clonazepam to settle my kettle."

   
9.0

EasyDoesItNS May 7, 2015

19 users found this comment helpful. Did you?   Yes   No Report as inappropriate

"I've tried a lot of other medications for my depressions an anxiety and they made me feel sick to my stomach. So I would stick to it. I was to busy trying push through my duties as a mother and wife. I couldn't feel sick to my stomach plus depression & anxiety. So when the Dr gave me Zoloft I was hesitant. I did take it the first day and I slept really well with NO drowsiness the next morning. I felt happy and focused. I was able to do the simple things like figure out what to cook for dinner. I have energy and a clear mind. I started with 50mg but I think I was getting used to it. So I started taking 100mg and so far so good! My husband notices a difference and loves it. It wouldn't hurt to at least to try it. I'm sooooo glad I did."

   
10

Leximarh (taken for less than 1 month) May 5, 2015

5 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "I started Zoloft about 2 months ago. I was taking 25 mg to start, as I am very tiny. After about a month, I increased to 50 mg, and the results were felt within days. I'm not hitting my dangerous lows nearly as frequently, and when I do get upset, it feels tolerable. Yes, I still cry; no, I'm not happy all the time, but that's normal! For the first time in over 3 years, I understand what it feels like to be normal. PS-for those of you out there desperately looking for help, but not wanting to disappoint your loved ones who are opposed to taking psychiatric medication, do it for yourself. Here's what might happen: they don't work so you stop taking them, or they work and you never look back. Life is far too short to feel awful throughout it."

   
9.0

Cat - 20 yrs old April 25, 2015

92 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "Pros: this drug gave me an energy boost that felt like it lifted my depression and increased my metabolism. My sleep schedule was normal, people said I was friendlier, and I had consistent appetite for healthy food. Cons: this drug took away my ability to have intimacy and perform any kind of exercise other than simple running on a treadmill. I could not play sports with any of my friends, because I would get lightheaded and faint, especially in the heat. I could not have a complete orgasm, and so that pretty much ruined sex for me. In summary, it treated several of my depression symptoms, but the things I had to give up due to side effects were not worth it. By the way, these side effects are a very common occurrence, not a surprise."

   
5.0

Steve Stevenson (taken for 6 months to 1 year) April 21, 2015

16 users found this comment helpful. Did you?   Yes   No Report as inappropriate

"Started taking 50mg sertealine for depression and anxiety, I started getting nausea after the first day, after a week it settled and after 2 weeks I felt a slight change in my mood but it seemed to be more effective for my anxiety. After 3 weeks I started getting some terrible side effects such as a bad stomach and diareha also long painful headaches. Anyway a month down the line I feel a lot better I can honestly say the medication is working although it has it's ups and downs try to stick with it, I would recommend seeing your Doctor to get the medication changed or the dosage changed if it has no effect because it's what I did. My quality of life has become so much better. I try to ignore the occasional side effects! Stick with it"

   
8.0

Liamh5659 April 19, 2015

18 users found this comment helpful. Did you?   Yes   No Report as inappropriate

"I've been on Sertraline for 5 months now I started out at 50mg and it seemed to be ok my anxiety attacks were becoming far less and I was a lot happier then about 3 months later I found I was having panic attacks again and now for the last month I've been on 100mg my mood is so bad it's affecting my relationship and I always just feel down and worthless I'm going back to the doctor soon to hopefully sort it out"

   
2.0

lisaxxxx April 19, 2015

7 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "I have been on Zoloft for a bit now and am on a 50mg dose. I find it has made a world of difference. I was taking it after dinner and had real bad insomnia and buzzing etc. So I told my doctor and we changed the schedule so I started taking it in the morning and I sleep great at night. Zoloft has helped with my depression and anxiety. I haven't felt this great since I can't even remember when. If your having bad side effects like the insomnia talk to your doctor and change the times you take your meds."

   
10

2344415emz2626266 (taken for 6 months to 1 year) April 7, 2015

36 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "Zoloft is a miracle. I was having panic attacks and anxiety and since taking them I feel so much better .I can sleep at night and wake up refreshed and feel I could climb a mountain. Truly a wonderful medicine."

   
10

sazz22 April 3, 2015

69 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "I was on 100mg of Zoloft and started suffering from severe insomnia after being on it only 2months. Dr tappered me down to 50 mg and then done in a week, withdrawls were dinging head, zap and buzzing ears plus severe insomnia."

   
5.0

Need sugessions (taken for 1 to 6 months) April 3, 2015

26 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "I've taken Zoloft off and on within the last 3 years. I do much better with it. I went from being so low that I couldn't take care of myself because of anxiety and depression. With Zoloft and better life circumstances I am doing much better. I'm actually happy! Right now I'm on 25 milligrams. Sometimes I'm on 50. When I had postpartum blues, 100 milligrams was necessary to feel positive."

   
8.0

red4 April 2, 2015

22 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "I got put on this medication about 3 days ago and my first time taking it was in the morning. There are two side effects I've had, the first day taking it I felt kinda nauseous and I threw up, but after that I was completely fine! I also have had a decreased appetite, but in my opinion that's a good thing, considering I want to lose a bit of weight. I was suffering for major depression, and got put on this medicine because I was caught in the middle of attempting suicide. But since I've started this, I haven't had a single suicidal thought! I would definitely recommend this. Although ive been on it for just a few days, I already discover improvement."

   
9.0

Amazing! March 31, 2015

30 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "Went on Zoloft after Celexa stopped working and I quit cold turkey(don't do!!) Made me feel 10x worse within days. Not for me. Now on Pristiq which helps but has horrible withdrawals if you skip or are too late for a pill."

   
1.0

Amr0k March 23, 2015

15 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "Zoloft has been a lifesaver. Something that helps keep my crippling MDD and SAD at bay and make it through life normally. Even happier as this was the 1st antidepressant I tried and it worked! Also no side effects at all. Thank you God."

   
10

Mohammad_au (taken for 6 months to 1 year) March 21, 2015

80 users found this comment helpful. Did you?   Yes   No Report as inappropriate

"This helped my panic attacks stop, but helped with depression none. This medication made me feel 'flat,' and like I was not living in the moment. For example, when people talked to me I could not associate emotions with the conversation. In addition, this gave me stomach irritation, made me lethargic, and never worked at the 4-6 week mark."

   
2.0

Evilmage (taken for 1 to 6 months) March 13, 2015

8 users found this comment helpful. Did you?   Yes   No Report as inappropriate

"Been on sertraline for 4 months now. Initially 50mg up to 100mg after the first two months and I feel really good. Better than I have in years, which is surprising as I think my depression only started within the last year. So perhaps I wasn't as carefree as I thought. My emotions are muted so no low lows but also no highs, so no feelings of joy or excitement - but I'm ok with that actually I'm ok with everything. I don't feel anxious, stressed, angry or frustrated. I feel confident because I don't care about consequences which is both good and bad. I've spoken to strangers, which is something I never did before... And I enjoy the interaction.. I'm really pleased with sertraline for my depression and the added bonus of reducing anxiety."

   
9.0

Paulzin March 8, 2015

0 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Zoloft (sertraline): "My 14-year-old son suffers from major depressive disorder/social anxiety disorder. He was previously on lexapro for 10 months, which worked well for his symptoms but gradually stopped working. He was switched to Zoloft and increased from 25 mg to 50 mg after a week. Only 3 days into the 50 mg dose he reports much improvement in his depression symptoms. It doesnt control his anxiety symptoms as well (yet) but we are hoping that will change in the next few weeks. Overall, he feels better on Zoloft. Takes it in the evening due to initial side effect of headache."

   
9.0

Momiftwo March 7, 2015

7 users found this comment helpful. Did you?   Yes   No Report as inappropriate
Page 1 2 3 4 5 6 7 8 9 ...Next

Learn more about Depression

Hide
(web2)