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Regorafenib User Reviews & Ratings

Brand names: Stivarga

Regorafenib has an average rating of 4.5 out of 10 from a total of 14 reviews on Drugs.com. 33% of reviewers reported a positive experience, while 50% reported a negative experience.

Reviews for Regorafenib

  • Cance...
  • July 20, 2017

Stivarga (regorafenib) for Colorectal Cancer "I am writing this as a data point for those who may be considering this drug. My mother was recently put on this and it was literally the worst drug she's ever taken in her 6 year journey battling cancer. I read the reviews and begged her not to take it, but she went through it anyway. The drug caused her to be lethargic to the point where she could not move, she had a severe loss of appetite, she broke out in hives, she lost a significant amount of weight and could barely walk/clothe herself. She literally could not function. She took it for two weeks and by the end of it was so incoherent and weak that she collapsed inside of our home. And this was from taking 2 pills one week, 3 pills the next."

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55 Report
  • Anonymous
  • Taken for 1 to 6 months
  • August 26, 2020

Stivarga (regorafenib) for Colorectal Cancer "My husband is going to begin his 3rd month of this med Stivarga on 8/29/20. Dosage is 4 pills a day/160 mg. He takes it on a cycle of 3 weeks on & 1 week off. His side-effects have gotten progressively worse as the 3 week cycle progresses until the point of he can barely function due to lethargy, severe weight loss (he lost 8 lbs in a month) & loss of appetite. Currently he is off medication for 1 week and each day his appetite & energy gets better. I dread 8/29/20 when I know his side-effects are going to return. So far we don't know if this drug is effective on his metastatic stage 4 colon cancer because his Dr hasn't ordered a CT scan yet. Written 8/26/20"

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19 Report
  • Tse
  • March 19, 2022

Stivarga (regorafenib) for Colorectal Cancer "My husband took this med 4 tabs for 3 weeks and 1 week off . Due to severe side effects down to 3 tabs for 3 weeks and one week off. But now due to severe side effects extreme lethargic in bed for last 3 weeks, He went to emergency twice due to bleeding but not sure from where waiting for endoscopy approval. Loss of appetite lost so much weight. Does not look like same person he was month before. Please don't give this to your love one for any reason. This is pure poison which is so bad cancer patient. I am so sad 2022 n drug company and doctors giving this poison to innocent and sick people. This is pure torture. Please don't give this to your loved one."

1 / 10
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9 Report
  • Bvsdslp
  • Taken for 1 to 2 years
  • November 7, 2017

Stivarga (regorafenib) for Colorectal Cancer "Have taken this medication for over a year. Carcinoembryonic antigen (CEA) well within normal range. Slightly elevated bilirubin. Only side effects are mild to moderate hand foot syndrome, some fatigue and nosebleeds due to low platelets. It is important to note that I have never done IV chemo, so my results may be different from others."

10 / 10
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20 Report
  • Teds...
  • Taken for less than 1 month
  • April 29, 2021

Stivarga (regorafenib) for Colorectal Cancer "My brother was a father, a brother, a son and a Marine. He was only 53. He was prescribed this drug after radiation and two other chemotherapy drugs had failed. He said the drug utterly robbed him of any energy and made him feel absolutely terrible. Three days after he began treatment, he suffered cardiac arrest while in bed. His wife called an ambulance and they were able to revive him then rush him to the ICU. Unfortunately, the diagnosis was sepsis due to a perforated bowel, which is generally considered unsurvivable. He died there four days later, surrounded by his mother, sister, brother and son. We are heartbroken and horrified at his suffering and will grieve always that he is gone."

1 / 10
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10 Report

Are you taking this medicine?

  • Still...
  • Taken for 6 months to 1 year
  • January 3, 2023

Stivarga (regorafenib) for Colorectal Cancer "I started on Stivarga 11 months ago after having had a rare and serious reaction to oxaliplatin, and progression on irinotecan, panitumumab, 5-FU and Avastin. During my first cycle, I started on 2 pills the first week, 3 the second, and 4 the third. Each of my following cycles I took 4 tablets, or 160mg daily x21 days, then off x7 days. Being an oral medication, it was easy to take. On my third and fourth cycles, I began having horrible diarrhea, sometimes more than 15 episodes in a day. I was admitted, labs and scans indicated a huge drop in my CEA. They also found that I had a bacterial infection in my colon. Once the infection was cleared up, I've had very few side effects, only occasional diarrhea. I had a PET scan and another colonoscopy last week. Both indicated progression now. I don't know where I would be if I hadn't taken Stivarga, or if I would even still be alive. I believe it at least slowed the growth of this darned cancer. I recommend it."

8 / 10
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5 Report
  • Sad
  • Taken for less than 1 month
  • February 11, 2021

Stivarga (regorafenib) for Colorectal Cancer "My husband had liver failure within two weeks of taking this medication, watch your loved one carefully for liver failure signs and symptoms. The warning is serious by the time we saw the MSK doctor for his 2 week blood work, it was already to late there was nothing they could do but send him home on hospice on Christmas Eve he died on January 21 He was a thriving 50 year old, who turned instantly. Unbelievably SAD."

1 / 10
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10 Report
  • Nomor...
  • Taken for 1 to 6 months
  • August 20, 2022

Stivarga (regorafenib) for Colorectal Cancer "In Late March, 2022, to make a long story short, my oncologist suggested I try Stivarga as another line of treatment. I have colon cancer, but it wasn’t debilitating until I started Stivarga. I was fully employed until May, 2021 when I made the decision to stop working to give my health more attention as needed for cancer care. I exercised at least 5 out of 7 days a week, running, long walks, weights, etc. well my Stivarga was delivered by UPS in February, 2022 and my oncologist prescribed it to start 2 pills a day week one, then 3 pills a day week two, finally 4 pills a day from then on. Three weeks on and the fourth week off. I had Extreme lethargy and zero appetite. I lost 30 lbs in 4 months. I would sleep for 8-10 hours at night, get up and have my low fat breakfast so pills can be taken and actually fall asleep with my cup of coffee in my hands. I’d lay down on the sofa and fall asleep again. The 3rd week of June, 2022, I quit taking It, and told oncologist No More."

1 / 10
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5 Report
  • Laila
  • Taken for less than 1 month
  • August 31, 2022

For Colorectal Cancer "My mother has stage 4 colon cancer for 5 years now. It has advanced and as last resort doctor recommended this poison. 2 weeks in 3 pills a day she became extremely lethargic. Hives head to toe. Extreme stomach ache. We ended up in ER. A CT scan later, cancer bas grown despite her taking this poison. So not only this poison robbed her 2 weeks of her life, it did nothing to the cancer. Shame on whoever approved this as treatment."

1 / 10
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1 Report
  • gabi
  • Taken for 2 to 5 years
  • November 14, 2022

Stivarga (regorafenib) for Gastrointestinal Stromal Tumor "I have been on Stivarga for 3 years. It has stopped the growth of GIST mild side effects. Take 120 mg every night at 11:00 p.m."

9 / 10
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12 Report
  • Harish
  • September 9, 2015

Stivarga (regorafenib) for Gastrointestinal Stromal Tumor "Only side effects and no result"

1 / 10
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20 Report
  • jasper
  • Taken for 1 to 2 years
  • August 9, 2021

For Gastrointestinal Stromal Tumor "I have been on stivarga for 18 months. few side effects and tumor has shrunk in half and continues to shrink."

9 / 10
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7 Report
  • Thexar
  • Taken for less than 1 month
  • October 16, 2023

For Hepatocellular Carcinoma "Initially, 2 days into treatment caused severe diarrhea. It's starting to improve a bit now. Time will tell..."

6 / 10
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1 Report
  • Thexar
  • Taken for less than 1 month
  • October 16, 2023

For Hepatocellular Carcinoma "Initial 2 days into treatment caused severe diarrhea. Starting to improve a bit now. Time will tell..."

6 / 10
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0 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.