The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Seroquel (quetiapine): I was off meds for awhile and thought I was fine - nope! Had a manic episode. I take 100 to 150mg of Seroquel at night. Before this, I took Geodon and lost weight, but I had uncontrollable muscle movements, I didn't want to switch but my family was embarrassed by my non stop hand movements. I switched to Seroquel and feel a million times better. I sleep great (used to not sleep for days). BUT, I have gained 40 lbs. I wake up the next morning and see what I ate the night before and get so irritated with myself. It makes me want to eat everything bad for me. If I don't eat, it's like an itch I can't scratch. I don't feel foggy, but well rested...then again, I sleep till 8 or 9am. To me, it's worth the weight gain to feel stable.
quetiapine: I am 59 years old, worked as a psych nurse for 28 years & am bipolar. My symptoms manifest in severe depression, anxiety & insomnia so bad I retired early. I have now been on Seroquel for 6 years & in combination with Lamictal * Requip I have been able to enjoy life, sleep well and managed well as an outpatient. Seroquel is for me a miracle. I spent many years addicted to Xanax & other benzodiazepines in a futile attempt to sleep & decrease the anxiety. I know that many psyche meds were originally meant to treat other illnesses & found to be beneficial in others so I feel extremely fortunate to finally have a medicine that works! I often joke with my friends that whoever discovered this medicine should get a Nobel Prize in medicine.
Seroquel (quetiapine): I take Seroquel for bipolar, I had side effects when first taking it such as couldn't wake in the morning and sluggish, it took me a couple of months to get used to it, now I take it at about 10.30pm asleep within 20 mins and up at about 8.30 am, well rested, it has been great for my mania, which can last weeks at a time. I feel so normal again, I take 100mg a night with 600mg of Tegrotol you just have to give it time to do it's thing, the side effects go away. I have no weight gain at all on Tegrotol, it's the opposite, I'm losing weight.
15 users found this comment helpful.
Seroquel XR (quetiapine): Works like a charm. It was prescribed for me for Bipolar I disorder (as part of my cocktail of meds), especially for symptoms involving lack of sleep. I have been struggling with sleep problems for so many years, and this works great for me at 50 mg. It even helps with depression and anxiety temporarily. I feel a lot calmer, which is definitely needed for me, especially at night. It helps with racing thoughts and voices as well. No more "noise" in my head at night for most part.
15 users found this comment helpful.
Seroquel XR (quetiapine): I took regular Seroquel which did help somewhat. I would rate that at a 4 out 10. I found about Seroquel XR when people told me to see a pdoc this was in 2007 because I was bipolar 1 and couldn't get it under control on my first visit with pdoc I told her my situation and Seroquel after my visit she gave me 2 samples of Seroquel XR which was only out 4 months at that time it has been a huge help with mania and depression I take 800mgs at bedtime when I wake up I take 400mg Lamictal that helps a great deal for me with the racing thoughts and impulsivity along with 2mg of clonazepam that has been a life saver it took many years in and out the psyc hospitals to finally get it right.
Seroquel (quetiapine): This is my 2nd time on seroquel and now that I actually know two shits about mental disorder, I really do like seroquel. I've always had a terrible time falling and staying asleep which it helps with greatly, and my ridiculous bipolar tendencies it puts to rest. I recommend seroquel if it works for you. I've never had a single negative side effect from it but some people do. Every brain is different :)
32 users found this comment helpful.
Seroquel (quetiapine): I have just started Quetiapine (Seroquel) going form 25mg to 75mg now. I was previously using lithium and have gradually reduced it to 250mg, now I do not take it and have replaced with seroquel. I am concerned about the side effects at higher doses and I would like to know if anyone has gone from using lithium to seroquel as a modd stabilsier. I am doing this as I am trying to get pregnant and my doctor has told me that seroquel is a good substitute up to the 2nd trimester of a pregnancy where I would re-introduce lithium.
Seroquel (quetiapine): I have been a bipolar as of 26 years. After my first and huge depression, I have not missed lithium not even for a day. I have had a really good acceptance to Seroquel, but not to Seroquel XR. The difference is huge, and XR plays with your sleep patterns and more. The insatiable hunger is so, so, true as is the weight gain. I just eat less and less and less and as a person who has had an amazing metabolism, still am 105lbs. After 3 children, my teen weight, I am now at 115lbs and I hate it. But I have no desire to stop Seroquel.
17 users found this comment helpful.
Seroquel (quetiapine): I've been taking Seroquel for about a year and I can honestly say I don't ever want to live without it. No other medicine had any effect on controlling my extreme mood swings and delusional/psychotic thinking.
The sleepiness (which I now find very helpful) and morning fog were bothersome, but I've gladly adapted my schedule to allow 8-9 hrs sleep nightly.
29 users found this comment helpful.
Seroquel (quetiapine): It worked well for sleep but I could not remember eating peanut butter and jelly sandwiches. I woke up with it all over my pillow and cheeks weird.. I felt hung over in the morning. Also was taking Geodon and Effexor. I don't take anything now. It's been 3 years. I'm doing good.
16 users found this comment helpful.
Seroquel (quetiapine): I too gained masses of weight taking Seroquel but lost it all (35lb) in 6 months by healthy eating & being AWARE of the pitfalls. Seroquel does not make you gain weight. Seroquel makes you crazy HUNGRY craving all the bad stuff - salt/sugar/fried food for me. The secret is to ANTICIPATE your munchies. Prepare a large but healthy snack in advance or save half your evening meal and have it at bedtime just before you take your meds. This really worked for me. Taking my meds on a full stomach took the cravings away.
50 users found this comment helpful.
quetiapine: Seroquel literally saved my life! After a suicide attempt landed me in the ICU 8 years ago, I was diagnosed with bipolar I disorder & subsequently put on Seroquel. Early on, my dose was increased to 300mg
& that's where I've stayed. A few years ago I started having trouble with depression again; although this time around it wasn't suicidal. My Doctor added Pristiq & it really seemed to help so I've stayed on it. When I first started the Seroquel, I remember waking up one morning and thinking "So THIS is what normal feels like!" I realize it isn't for everyone, but for me it's been a miracle that has allowed me to live a happy and STABLE life! Without serious mood swings, I can actually make (and keep) plans!
Review by Patient67 (taken for 6 months to 1 year):
Seroquel (quetiapine): I suffer from mainly depression and anxiety. I have had a few bouts of hypomania. This was recommended to me to help anxiety and mood swings. Within an hour of taking this medicine I was always somewhat buzzed and not in a good way. Like you have to lie down and sleep or you will become extremely irritable. The sleep was great on it, however you wake up in a fog for hours. Usually until dinner time for me. It really flattens you out so you don't feel much but emotionless and tired. I took anywhere from 50 to 200 mg and the result was the same. I am off now and trying safer meds. Seroquel wasn't for me, glad it helps millions though!
22 users found this comment helpful.
Seroquel (quetiapine): I was diagnosed bipolar about 15 years ago and have been on and off many medications. I now have insomnia and Seroquel is the only medication I have found that will help me sleep (besides Geodon which gave me involuntary muscle spasms) I take 100mg a night. It does make me sleep a lot, which I really like. I usually sleep from 11pm to 8:30 or 9am. Thankfully I don't have to be up early for any reason. I feel so stable and happy and rested on it. The reason I rated it a 9, instead of 10...major weight gain. 30lbs and it hasn't stopped. I did recently try to switch to Latuda because of weight gain and I was miserable with no sleep. I wish Geodon had worked because I actually lost weight on that.
21 users found this comment helpful.
Seroquel (quetiapine): This medicine worked at first, but after taking it for a few (2) weeks, I developed anxiety & panic attacks. I've had panic attacks in the past but not like these. I wasn't afraid of anything specific; it was like a constant fear. Also, my heart would race so bad. I am being weaned off this & switching to Zyprexa.
20 users found this comment helpful.
Seroquel (quetiapine): Seroquel 100mg saved my life. For 9 months I did not sleep because of an anxiety disorder. I tried to kill myself three times. Finally i was given Seroquel and 130mg trazadone. I have been sleeping well and not depressed for ten years. It has saved my life I am so grateful. Did put on 50lbs better that than being dead. Very grateful.
18 users found this comment helpful.
Seroquel (quetiapine): I have tried just about every medicine there is to treat bipolar disorder, and Seroquel hands-down is the best one for me in terms of stability. However, the weight gain has been a problem. I gained 40 pounds on Seroquel. The good news is I've lost 16 pounds of that in 3 1/2 months. It's been hard work, but I am confident I can meet my goal of losing 48 more pounds over the next year.
23 users found this comment helpful.
Seroquel (quetiapine): I have had Bipolar one for 8 years now. I use 50 mg of Seroquel, with 100 mg Lamictal, and 900 mg of Trileptal. Seroquel is great for sleep, which is critical for me. I also use good sleep hygiene with the Seroquel to make sure I get my 8 hours every single night. I am managing my bipolar very well, and for this I am very thankful to these medicines.
18 users found this comment helpful.
Seroquel (quetiapine): Seroquel is fantastic. I've been taking it for bipolar and inability to sleep. The only problem I've had is severe restless leg syndrome. That side effect is knocked out by 2 mg of Requip.
21 users found this comment helpful.
Seroquel XR (quetiapine): It worked well, my moods were more stable. The only downfall was that I gained 20 pounds. As a bulimic and anorexic this terrified me. I ended up going off of it to lose the weight.
12 users found this comment helpful.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Data sources include Micromedex™ (updated Dec 30th, 2013), Cerner Multum™ (updated Jan 17th, 2014), Wolters Kluwer™ (updated Mar 2nd, 2014) and others. To view content sources and attributions, refer to our editorial policy.