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Nystatin User Reviews & Ratings

Brand names: Bio-Statin

Nystatin has an average rating of 4.8 out of 10 from a total of 98 reviews on Drugs.com. 31% of reviewers reported a positive experience, while 46% reported a negative experience.

Reviews for Nystatin

  • Kay...
  • June 30, 2019

For Oral Thrush "I was on antibiotics for an extended time and after 4 months I developed thrush. After starting this medicine I noticed my mouth because extremely dry, especially at night during sleeping. My tongue had a funny burning feeling and everything taste funny. Has anyone else had this same problem? Also I got really bad diarrhea and stomach cramps."

2 / 10
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193 Report
  • Regis...
  • Taken for 1 to 6 months
  • December 13, 2020

For Oral Thrush "I have used Nystatin twice in 6 months because I take an inhaled corticosteroid, which has caused thrush on tongue especially in posterior of tongue. A couple things are be sure to swish nystatin aggressively and gargle as well to help access very back of tongue. Then do not eat a drink for 30 MIns. Lastly using a tongue scapper to remove loss debris and clean tongue."

9 / 10
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  • Chris...
  • Taken for less than 1 month
  • May 13, 2020

For Oral Thrush "Laryngitis for 6 weeks that gets worse as the day goes on to the point that by the end of the day it physically hurt to talk but with COVID was scared to see doctor. No other COVID symptoms. Finally saw doctor, no COVID, no strep, 2 weeks later, no improvement, tested for COVID again, negative again but this time, doctor diagnosis thrush (no idea how you get that???) and gives me nystatin 4 times a day. Day 2, voice sounds better, lump feeling in throat almost feels gone, I can talk, throat not so painful but tongue feels like I ate a bag of sour candy. When I take the nystatin, it tingles on tongue- is this normal? Should my tongue hurt like this afterwards as well?"

6 / 10
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Frequently asked questions

  • Maia
  • Taken for less than 1 month
  • April 26, 2019

For Oral Thrush "I had oral thrush on my tongue. The Nystatin cleared it in a few days, but since then (6 weeks ago) nothing tastes the same anymore. It's as if its effected my taste buds and mucous membranes. My tongue feels strange, slightly scalded and very squeaky against my teeth and the inside of my mouth. It's as if there's enough saliva but it's not slippery enough. It's really unpleasant. I'm assuming it was the Nystatin that caused it and really hope it returns to normal soon as I don't enjoy anything I eat or drink."

5 / 10
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127 Report
  • Kim
  • November 20, 2019

For Oral Thrush "I've had oral thrush for approx 3 months, I got it from being extremely stressed and anxious. (Yes,I never knew you could get it that way either) I was on duflucan for 7 weeks, and it didn't touch it, I'm beyond frusterated with this. Today I quit the diflucan and went to nystatin 5X a day. Please pray this goes away from me. "

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114 Report

Are you taking this medicine?

  • Jimpe...
  • July 26, 2019

For Oral Thrush "Prescribed Nystatin for oral thrush after 10 days on Amoxicillin. My throat was red and raw, my tongue hurts, sores on back/sides of tongue. Nystatin made a huge difference within just a couple of days. It has slowly improved each day as I have taken it 4x/day. I’m on day 7 today and I would say it’s almost gone... still getting some discomfort on tongue on and off - taking Advil for that. I’m confident it’ll be all gone by day 10 of the medication. I’m extremely hopeful."

9 / 10
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112 Report
  • Shay
  • February 3, 2021

For Oral Thrush "This is my second round with nystatin, which came back about a month after having thrush for 3 months, because I was put on antibiotics for a staph infection. I combine the nystatin with holistic measures, #1 being diet. NO carbs, sugar or alcohol, as candida thrives on sugar, and carbs and alcohol break down into sugar in the body. The last thing you want to do is to feed the candida fungus. The first round didn't work at all, and I suspected actually made it worse. This time I caught it early and started right away on the diet, Candida-Killer-tea, baking soda swishes, and hydrogen peroxide swishes. I didn't start with the nystatin until a few days in. I noticed after 24 hours that it had gotten worse, so I researched the ingredients. First ingredient: Alcohol! It also contains sugar! Nystatin also contains saccharine, which upsets the flora system....again, the last thing we need. In a nutshell, nobody should take this medication as it is counter productive."

1 / 10
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71 Report
  • Jin...
  • Taken for less than 1 month
  • July 5, 2019

For Oral Thrush "I am using Nystatin Oral 4 times a day for 7 days. Been on many rounds of antibiotics for recurrent UTI infections and such..so end result is thrush. So Nystatin is not working for me at all. I have been on 3 bottles of it already, it's made very little difference. I switched to natural apple cider vinegar remedy and it seems to clear it way faster then the Nystatin."

3 / 10
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88 Report
  • brain...
  • July 11, 2009

For Oral Thrush "My father, a brain tumor patient, had oral thrush, which is very common for those taking long-term Dilantin. This swish-and-swallow medication worked wonders for him, within about 3 days. Be sure to take it for the full prescription period, usually 14 days. Also, the longer you can hold the gargle, the longer the contact between drug and organisms. Thrush can also move from the mouth into the throat, and it can recur quickly, so out of sight doesn't necessarily mean anything. Again, take it for the full period recommended by the doctor."

10 / 10
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195 Report
  • Ash
  • April 2, 2020

For Oral Thrush "I developed oral thrush for the first time after taking macrobid generic for UTI. The antibiotic made me outrageously ill from all of the extreme side effects I experienced. I was able to get nystatin over the phone. However I immediately had a severe reaction of chest tightness, rapid and abnormal heart rate. Luckily about 24 hours later it seems to have subsided but now I’ve been trying everything I can OTC. Nothing is giving me relief. The feeling in my throat is horrible and sometimes it’s unbearable and impossible to swallow. I’m definitely dehydrated as I cannot even force myself to sip let alone drink water. Doctors have been less than helpful as they don’t want to see patients due to social distancing guidelines from COVID. I’m Hoping the use of baking soda and saline mouth washes as well as acidophilus probiotic pills will start being effective as I can’t take much more of all of these issues. (Within 15 mins the nystatin reaction set in)"

1 / 10
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65 Report
  • Amanda
  • Taken for less than 1 month
  • May 4, 2020

For Oral Thrush "I actually developed oral thrush from something really bizarre... So because I had to work during this Corona virus crisis.. Every time I came in I was so paranoid about something being in my mouth.. Like virus particles that I was rinsing with an extremely heavy alcohol mouthwash. I developed thrush because of this.. I have been taking this medication for about 2 days. So far it has not helped. I noticed that somebody else wrote something which is actually happening to me also which makes me a little nervous.. I have been having some kind of weird twinges in my chest. I am really paranoid that the infection has spread down my a oesophagus and into my lungs. This is a possible complication of thrush. I will give it another 2 or 3 days and then I will go back to the doctor the only problem is I'm really scared because I have to go to urgent care and with everything that is going on I am so paranoid about going to urgent care."

3 / 10
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58 Report
  • JanieK
  • October 11, 2019

For Oral Thrush "I was on Nystatin for about 10 days. Unfortunately no one, including Walgreens caught the fact that it is contraindicated when one is taking Warfarin blood thinner, ie there is a drug interaction between the nystatin and warfarin . Had a GI bleed. Almost did not survive this screw up. Look up every medication prescribed and if you have questions or weird symptoms, ask for extra info before ingesting. We have wonderful medical technology, but screw ups are rampant. ."

1 / 10
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  • Joe
  • Taken for 1 to 6 months
  • June 5, 2020

For Oral Thrush "Nystatin is absolute garbage. I’m now on my 4th bottle with no sign of it doing anything. I’ve also pumped myself with probiotics and limited alcohol. Very frustrating and Nystatin seems to do nothing. Tastes good at least but not effective. Based on so many other negative reviews it’s surprising how popular this is prescribed to adults with oral thrush."

1 / 10
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50 Report
  • Dwain
  • Taken for less than 1 month
  • November 27, 2019

For Oral Thrush "Well I didn't use nystatin, I use essential oils, not a fanatic user of, but knowing tea tree oil is a fungi killer, so salt water ,tea tree oil with a splash of mint spray and water is working great, just trying to stay off the sugar and yeast canidida diet is hard but the essential oils is working. Was prescribed predisone and anti-biotics for 5 + days after 4 days in hospital with double pneumonia."

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  • Awano
  • Taken for less than 1 month
  • September 13, 2020

For Oral Thrush "On 2nd bottle of Nystatin for oral thrush at back of tongue, it seemed to work initially but symptoms getting worse now. I'm struggling with bad breath, metallic taste and sore tongue and loss of appetite. I guess I have to go back to GP."

1 / 10
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44 Report
  • Verym...
  • Taken for less than 1 month
  • July 25, 2017

For Oral Thrush "Maaan is this medicine a gift from GOD!!! It works wonders and I am only on day 3. I've been suffering with unknown Candida for 4 years with it now affecting my stomach, throat and tongue. The coughing has subsided and my tongue is amazingly clear! I thought I was an alien of some sort dealing with a weird looking tongue all of these years but thanks to my Dr's diagnosis and prescribing Nystatin I feel sooooo much better. I suffer with Systematic Lupus and all of my medicine's are causing the thrush. Amazing product and it doesn't taste half bad either. My only gripe Is that nothing taste the same anymore but maybe that's temporary."

10 / 10
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62 Report
  • Waf
  • Taken for less than 1 month
  • November 8, 2019

For Oral Thrush "I’m currently having chemo and with my low wcc developed a lovely case of oral thrush. It was really sore to swallow and the back of my throat was pretty coated. Been taking nystatin for 2 days and have already noted a great improvement so thumbs up from me. It doesn’t taste to bad either"

8 / 10
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  • Kano
  • Taken for less than 1 month
  • October 26, 2020

For Oral Thrush "I've not had oral thrush before. I am a smoker, tho not real heavy. I also have dentures that don't fit correctly. So, dr. put me on nystatin because the back/side of my tongue hurt on both sides. I finally looked at it in mirror and saw white spots. It starting spreading on the back of my throat and tongue. I took one dose 4x a day faithfully. It started clearing up after about my 5th day of taking med. So everything was fine until 3 days after my med. ran out. Its now back and starting the same way as last time with my tongue hurting on both sides. Dr. is going to do another treatment, same as last one. If it doesn't stay away they want to send me to ear/nose/throat dr. and have biopsy done. Now I'm really freaked out and anxious. I didn't get any side affects from this med. and feel it worked well, but don't understand why it came back."

8 / 10
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33 Report
  • Illin...
  • Taken for less than 1 month
  • July 30, 2014

For Oral Thrush "63 yrs old, was prescribed liquid, 120.00 nystatin, 100,000 unitls/ml, 2 tsp., for 4 times a day as needed, for thrush that was in throat, and I believe going into esophagus. Was not in mouth this time (had it 6 yrs ago). Read where hydrogen peroxide kills it, and had been using toothpaste with hydrogen peroxide in it, so wasn't on tongue. But throat hurt, was actually coughing up blood in sputum. Only two doses and throat and chest doesn't hurt, coughing has lessened, and I believe bleeding has stopped! Notice the dose is for kids, but I'm 63. But it is working! Could hardly swallow, hurt so much. Not hurting so after only 2 doses. Amazing medicine! Was given 3 day supply."

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  • Meme
  • May 24, 2018

For Oral Thrush "I was diagnosed with oral thrush after first being told the sores on corners of my mouth were caused from drooling in my sleep. It was a year or so after I rinsed my mouth out with mouthwash that my tongue developed sores and became so painful and my throat tried to close that I saw my doctor. She diagnosed oral thrush and gave me Nystatin. This is second day and already knot is gone from my throat. This is truly a wonder drug for this horrible condition. I smoke, take other meds and wear dentures which makes me a candidate for the thrush. If it comes back after I get it healed I will get more Nystatin."

10 / 10
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42 Report
  • Dale
  • Taken for 1 to 6 months
  • September 6, 2020

For Oral Thrush "Just finished my 2nd bottle of nystatin for oral thrush. Ever since then I wake up with severe dry mouth. My heart even skips a lot now. This dry mouth is so bad when I sleep it is horrible. Now not sure if the oral THRUSH is even gone. Now on my 3rd 14 day treatment with this junk..... Seems to get rid of Thrush for only a week or so. May have to do pill next. Pill can cause heart issues tho so trying to avoid it"

1 / 10
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29 Report
  • Suz
  • Taken for less than 1 month
  • April 8, 2021

For Oral Thrush "This medicine is awful. Took 5ml and it burned and made my cheeks swell and mouth burn. Told my Dr. He said just try out a little more so I only used .5ml. My tongue hurts so bad. Feels like I've been chemically burned. Called pharmacist. He said stop taking it immediately. This stuff isn't good for me."

1 / 10
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23 Report
  • Kiki
  • Taken for less than 1 month
  • April 21, 2020

For Oral Thrush "I’ve been on Nystatin for 7 days after being diagnosed with dry mouth. I have not seen any improvement for oral thrush. I am going back to the Dr to ask for a stronger medication for this damn white tongue."

1 / 10
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28 Report
  • Invad...
  • Taken for less than 1 month
  • June 15, 2021

For Oral Thrush "So far I’ve been on Nystatin “mouthwash” for 4 days and it’s been miserable. My mouth is so dry it’s uncomfortable and my tongue feels raw and dry. Nothing is helping so I’m beginning to wonder if this side effect isn’t from overusing. My thrush cleared in 2 days with this, so by all means it’s amazing for oral thrush, but I’m beginning to wonder if it’s not just burning my tongue since there’s no longer thrush in my mouth to fight?? That rubber banana flavor is quite literally vomit worthy, my tummy has been making LOUD noises and like others, I’ve had a few strange heart palpitations(?) after taking it..but it DID work (4ml 4x daily) to clear the icky. I cannot wait to be done with it."

10 / 10
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21 Report
  • Cjano
  • Taken for less than 1 month
  • November 4, 2019

For Oral Thrush "Taking Nystatin for thrush that was caused by Protonix. Sadly this is giving me chest pain and causing my heart to race for 1.5-2 hours after taking it and only intensifies every time I take it. Pharmacist recommended that I stop taking it and call my doctor. I hope something else can clear the oral thrush."

1 / 10
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28 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.