The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Provigil (modafinil) for Narcolepsy: I was diagnosed with narcolepsy in 1998. I have been on Cylert, amitriptyline, Ritalin, ambien, and now Provigil. The Provigil is a life saver. I did lose weight on it at first, but have leveled off and have not lost any weight since then. I have taken Provigil for 2 years now. It is not an "upper" and does not make me feel drugged. I take 200 mg in the morning. It does not wake me up, it helps me maintain the wakefulness that I need to get through the day. Without Provigil, I would not have a normal life. I am thankful to have found this drug. I would, however, like a generic to it that would help to offset the exorbitant cost of the drug.
45 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Narcolepsy: I was diagnosed with Sleep Apnea, for that I got a CPAP. But I also had trouble with zombie episodes and uncontrollable sleepiness (at work, while driving, very scary). I was diagnosed with Narcolepsy several years ago (not formally tested though). I have all the symptoms (night terrors, sleep paralysis.), but I have not been tested for it. Anyway, my Sleep Doctor put me on it primarily because of several driving issues. It seems to work well, I have not dozed off or had a zombie episode since I have been on it. I still feel tired, and I can sleep if I want to, so I feel a little more in control. I also don't feel like a speed freak, like Adderal. I am on 200 mg in the morning for the past 2 weeks. So far I am pleased with it.
Provigil (modafinil) for Chronic Fatigue Syndrome: After months of absolutely debilitating fatigue and an awful quality of life, I finally found something that makes me feel like I am alive. I would experience such extreme tiredness during the day until it was affecting every aspect of my life. I work 8-5 Mon-Fri. and would go to sleep at night and still wake up feeling awful. I actually felt like I had been 10 rounds in a heavyweight fight every day! I would spend all day in an absolute fog and by the time I would make it in from work I would be yawning so much until tears would be pouring down my face. I was bone weary tired! I have the good fortune to have an excellent family doctor who helped me feel alive again. 100 mg a day. I have my life back!
35 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Obstructive Sleep Apnea/Hypopnea Syndrome: This is my second day on Provigil 200mg once a day and was hoping for a dramatic change but there was none. I have sleep apnea and CPAP was not enough. Passed out at work and not safe to drive. I can say I am a little more clear and not in sleepy fog. Hoping that it will get better or up my dose
11 users found this comment helpful.
Did you?YesNo
modafinil for Chronic Fatigue Syndrome: I just started taking it last week and have not noticed any difference yet. It's expensine, even with my insurance.
Provigil (modafinil) for Chronic Fatigue Syndrome: I take this pill only as needed because of the price, so I take it if I have an appointment or have to be somewhere on time or before 4 pm. I am a zombie if I don't. I just can't understand why it costs so much. Do they honestly think people can afford to pay this price?
41 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Narcolepsy: Provigil made me lose my appetite at first, I lost about 20 pounds. The energy was great for a few months but it lost it's effectiveness. It only took me four months to reach the maximum dose.
14 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Narcolepsy: For several years, I have been on Provigil, with a small dosage of Ritalin as a supplement. The Provigil was not enough for me, but it was much better than being on Ritalin alone. Ritalin had a tendency to make me anxious and talk constantly. Life is good now as a narcoleptic.
12 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Depression: I've used it for 10 days now in my most recent attempt to kick meth. It helps so much. It won't buzz you, but it takes away the debilitating lethargy and depression.
34 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Narcolepsy: I was recently diagnosed with narcolepsy and started on Provigil. I started with 100 mg in the morning and then 100 or 150 mg in the afternoon. The first few days I was a little dizzy at first, a little nauseous, lost my appetite, had a mild headache every night (ibuprofen took care of that), and tense jaw/neck muscles. It was working great, but once I started classes (i.e., inactivity), I was falling asleep sometimes before my noon dose, and everyday around 6pm or 8pm. So, my doctor upped it to 200 in the morning and 200 after noon. For all 3 days of it, I was awake, only crashing around 8pm, but I was having problems with my memory and concentration. Just switched to Ritalin.
10 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Narcolepsy: I was diagnosed with Narcolepsy about 2 weeks ago. For 2 months I had been nodding off at work and at home, it got really bad when I nodded off while at a stoplight driving and when I got "written" up for sleeping at work. I was given Provigil to help me out which when I started taking it, it was like a miracle drug. I felt alert and not drowsy all the time. After 5 days I started feeling nauseous and then 2 days later out of the blue it stopped working. My Doctor put me on Ritalin but I'm still having problems later in the day, on my way to see a sleep specialist.
11 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Narcolepsy: I was given Provigil for my narcolepsy, with dosage of 200mg/3 times daily. For the first 3 days it was amazing I had forgotten what it felt like to be 'awake'. Unfortunately, after just 3 days it was not effective at all. My neurologist nodded knowingly when I told him. He said that's how long it takes to metabolize. Apparently that's when you can tell if it will work for you or not. I'm now on Aderall, 20 mg/3 daily and it is working much better for me.
13 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Narcolepsy: I started taking Provigil about a year ago when it was suspected I had narcolepsy. I was tested and found it was Idiotic Hypersomnia (lack of melatonin) they call it Idiotic because they don't know what causes it. Provigil works one day for me then not the next. You can only take 200mg max per day. I went off it and on Ritalin. I am awake without any ill effects. I have recently been tested again for narcolepsy and was found that I am narcoleptic. The test given last year was done incorrectly (without my C-pap), it was supposed to be done WITH it on during my sleep study. All is good now.
Provigil (modafinil) for Obstructive Sleep Apnea/Hypopnea Syndrome: My first 30 days on Provigil (200mg x 2 daily) were literally a life changing event. I have never felt so energetic, awake, and constantly in a good mood in my life. However, after 30 days the effects started to wane and, after 90 days, I feel little benefit. I tried taking an additional 3rd supplemental dose of 100mg a couple of hours after my second daily dose of 200mg to see if the good results might return, but all I gained from the additional 100mg was a headache. There is a definite and very unfortunate tolerance problem with Provigil in my experience.
23 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Narcolepsy: I took Provigil for 6 months with varying doses (100-300mg/day). It only took about 20-30 minutes to kick in and lasted roughly 7 hours. It gave me an incredibly high level of alertness. I also have mild cataplexy and sleep paralyzation, and it seemed to help keep both of these under control. However, it also gave me very bad nausea and an even worse headache. When the medicine wore off, my body reacted by immediately having a strong "sleep attack". If I didn't take my next dose before the first had worn off, the second didn't seem to work. Also, my urine smelled strange and the smell got even stronger when I drank more water. This stopped as soon as I changed my medication to Adderall.
20 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Narcolepsy: This is the first prescription I have taken for Narcolepsy. It has been 3-years now while taking 200mg's 3x a day. It turns out that naps are going to be a part of life. More particularly for the peak periods just to get over that tough time during the day. I would highly recommend letting your employer know about this condition. Narcolepsy is a handicap, of which you are protected. In other words, if you are caught sleeping on the job, they can not fire you for it. They need to make considerations for this condition and develop a work schedule that allows you ability to work a full shift. Provigil has worked well for me. I wouldn't want to go back to the way it used to be.
13 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Narcolepsy: Pros: Works well keeping me alert, no significant downer when drug wears off, can be used on an as needed basis. Cons: EXPENSIVE!
19 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Chronic Fatigue Syndrome: I take 400mg/day for fatigue and mental fog. It helped a great deal although after 3 years it doesn't work as well as in the beginning. I started taking 200mg/day and it didn't help until I took it for 3 months. Increased to 300mg/day after 1 year and to 400mg/day after 2nd year.
40 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for ADHD: I've been using Provigil in combination with Wellbutrin for my adult ADD. I'm almost 50 and was just diagnosed 3 years ago. I tried the stimulants and like the way they helped my concentration and focus but I couldn't take them because of my high blood pressure. I've also tried Strattera which worked really well but again I couldn't deal with the side effects (not being able to urinate can be painful). Provigil really helps slow down my racing thoughts but it doesn't seem to help with my concentration or distract ability. I take it first thing in the morning and usually can't get to sleep until midnight or 1.00am. Luckily I work at home so that's not a real problem. I'm glad to see it's worked well for some of the others who have posted comments.
20 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Depression: This turned me from a deep, suicidal depression into a happy, productive person in 2 days. I am also able to sleep without any sleep medicines (first time in years). My problem is that my insurance refuses to pay for it because using Provigil for depression/bipolar is off-label, and it is so expensive that I'm just starting to wean myself off of it, sadly. There is another drug, Nuvigil that is supposed to be even better, and is currently being tested (very positive results so far) for FDA approval in the use of it for depression and bipolar. It's been a long road for me, so I can only pray that the FDA moves quickly on this.
80 users found this comment helpful.
Did you?YesNo
Provigil (modafinil) for Narcolepsy: Not effective for me, I took the 200mg once a day for 2 weeks. Did not have any reactions good or bad. Just no effect at all.
11 users found this comment helpful.
Did you?YesNo
modafinil for Narcolepsy: This is the first and only drug I've ever taken for narcolepsy and my standard of life, work, etc. has improved incredibly since then. I do get the side effects (dry eyes, dry mouth, crawling skin, headaches, tummy problems and ironically enough: sometimes tiredness too) but these are subsets of one main side effect - massive dehydration. So I just drink lots of water and am mindful of it. Once you get over the main onset headache (which admittedly took me a few weeks), the benefits far out way the cons. I'm lucky with the costs as I live in the UK so 6 boxes x 30 tabs(200mg) only costs the price of a prescription (about
Provigil (modafinil) for Depression: This is a WONDER DRUG in the use of depression. I have suffered for years with depression and never with any relief from the mainstream anti-depressants. Either the side effects were intolerable, or the medicine just didn't work. Within 3 days of taking Provigil, I was the happiest, most productive I had been in a year. The first 2 days I was still really sleepy, and the 3rd day, a little hyper, but after that day I have felt EXCELLENT. I don't have anxiety attacks anymore and I get a full night of "good" sleep and wake up feeling extremely refreshed and I am happy again. I was on my couch for a straight 6 months sleeping and crying until I started this medicine. It literally saved my life.
204 users found this comment helpful.
Did you?YesNo
modafinil for Depression: I use several antidepressants, and I cannot function without them. Modafinil helped with my chronic fatigue, but it's not an antidepressant in my opinion. I can do a lot of things now. I'm so glad I heard about it. I take 200mg a day.
Biomarkers may be the key that opens the door to discovery of successful initial treatment of depression In a National Institutes of Health (NIH) funded...
Ritalin activates specific areas of the brain in children with attention-deficit/hyperactivity disorder (ADHD), mimicking the brain activity of children...
One in 10 teens admits to using a prescription stimulant or amphetamine to boost their performance in school, but most parents aren't aware of the scope of the...