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Remeron for Major Depressive Disorder User Reviews

Remeron has an average rating of 7.6 out of 10 from a total of 58 reviews for the treatment of Major Depressive Disorder. 67% of reviewers reported a positive experience, while 12% reported a negative experience.

Remeron rating summary

7.6/10 average rating

58 ratings from 65 user reviews.

Compare all 58 medications used in the treatment of Major Depressive Disorder.

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7%
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7%
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Reviews for Remeron

  • Grub
  • Taken for 1 to 6 months
  • March 20, 2021

"I have been on Remeron for 5 weeks. Before taking this I had extreme anxiety, I felt like I had a steel band tightening around my midriff, heart beating like it was going to explode, shaking when I had to go out and lack of sleep. Now on this I have the confidence to go out, my heart rate feels normal and thank goodness the steel band has disappeared. I hope this has been helpful to someone out there, good luck"

10 / 10
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242 Report
  • Anony...
  • September 10, 2019

"30mg every night for PTSD, panic disorder and major depression. dealing with childhood trauma like physical and emotional abuse, sexual assault from a young age. Mind doesn't race as much, don't have dangerous thoughts anymore. I still experience panic attacks, occasional chest tightness if I think about it, but panic attacks have significantly gone down to at least maybe once a month if not every other month. I have gained few pounds. If you have a sensitive stomach, eating right before or after taking this medication else you'll feel bad waves of nausea. My parents hid panic disorder as a child and lied to me about it so, I started experiencing them much more often in high school. have I honestly never felt better mentally. I can't say enough good things about this medication! Wait it out if you really think this will work for you. I had tried 6+ medications, this one works miracles and my mental health is 70-75% better."

10 / 10
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191 Report
  • Tk46
  • Taken for 2 to 5 years
  • February 23, 2024

"Remeron has helped me greatly with my anxiety and intrusive thoughts. My anxiety was so bad that I couldn’t eat or concentrate. Once I started taking Remeron, my sleep improved, my mood improved, and my appetite is back. I would highly suggest giving Remeron a try. Only downside for me personally is the weight gain. The cravings on this medication are very hard to control at times, especially at night."

10 / 10
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9 Report

Frequently asked questions

  • David...
  • Taken for 1 to 6 months
  • February 13, 2023

"I've taken this medication for four weeks before leaving a review. I was previously on Sertraline for four years which helped but caused regular headaches and made sleep problems worse. Mirtazapine helped with sleep immediately after I started taking it. The first few days I could have slept all day but soon got into a regular sleep routine. After eight to nine days I noticed that my mood had stabilized and within the first two weeks, I was feeling much calmer. Extreme and erratic thinking had been subdued. This may have been, in part, to improved sleep as well as the medication itself. After three weeks I noticed a very real difference as my 'brain fog' disappeared. This was an almost overwhelming improvement. I am 50 years old and suffered from depression/anxiety since childhood. My education and work life have been adversely affected by a lack of concentration and 'agitated' thinking. For the first time in my life, I am able to sit at my desk and work for hours at a time."

10 / 10
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53 Report
  • Pips
  • September 25, 2019

"K, been on this drug Remeron for depression for the longest time ! Have been on sooo many different drugs, worked for a while, then nada, side effects etc. My history, for 20 more years, is major depression and anxiety disorder. Partial personality disorder, it’s kicking in now, sorry. Remeron has been a God send to me for a long time. I , along with others, would highly recommend this."

10 / 10
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134 Report

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  • rubbe...
  • Taken for 6 months to 1 year
  • September 7, 2020

"Mirtazapine took my depression away in as little as 5 days. It was great, now I can live. 5 months later I started having severe bouts of breathlessness. My Psych says it is not the drug, it is anxiety. I stopped the drug for three days and the symptom totally went away. I went back on it real quick cuz the depression came on fast. Doc put me on .5mg clonazepam twice a day, but doesn't help the breathing. Anybody else have this breathlessness?"

9 / 10
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108 Report
  • Geral...
  • Taken for less than 1 month
  • October 25, 2020

"I'm on week 4 of mirtazapine 30mg and still feeling anxious. I have some really good days, so I think the tablet has started working, but then the next day I can be anxious all day long, which then disheartens me. Im wondering whether to stick with it ? Any experience would be welcome."

7 / 10
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102 Report
  • Prentes...
  • Taken for 5 to 10 years
  • March 24, 2023

"I read about Remeron somewhere online and asked my doctor for it. I take 30 mg daily. It helps with depression and helps me sleep. Take it right before you go to sleep. If you take it earlier, you might get hungry. Because this medicine makes food indescribably delicious. Get this drug. It will help you immensely. Good luck!"

10 / 10
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39 Report
  • Hungr...
  • Taken for 5 to 10 years
  • July 16, 2019

"I love Remeron! Even though it doesn't work sometimes, it definitely helps with mood, sleep, and your appetite when it does. I guess bc I've taken it for so long, my body thinks it's a Skittle. But skipping a week or just taking it when needed has better results for me. Without it, I tend to lose weight everyday from the effects of not eating when I'm busy. This helps me to keep my appetite and energy up until the next dosage. I hope this post and the medicine helps someone else as well. Just do not forget about the symptoms, be prepared for them, and enjoy ur life on Remeron!"

8 / 10
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119 Report
  • steverh
  • Taken for 2 to 5 years
  • July 20, 2014

"I was on Remeron for about 2 years before. Helped very very much with my depression. But although I often felt very sleepy near the beginning of the treatment, the massive fatigue eventually subsided to an acceptable level. 20-mins after taking it, I'm ready for bed I can't keep my eyes open no matter what. I just restarted Remeron two days ago, after more than a year being on it. As I type this, I feel fogged over, sort of sleepy, and immensely "munchie". As before when I took it, I'd find myself waking up several times a night going to raid the fridge and cabinets for munchie or sweet foods (and meats! definitely craved meat all the time). So again, on Remeron: eating again, sleeping some, more relaxed, less sad. "

10 / 10
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184 Report
  • jeffd...
  • Taken for less than 1 month
  • October 3, 2014

"30 mg. dosage; What to possibly expect based on my experience. Day 1. I was extremely tired & if I let my head hit the pillow, I would experience micro sleep. I felt a little dizzy at times. Be careful around stairs if you suffer from vertigo. Functionality was delayed - my mind was in a cloud & it was difficult to work or concentrate on something that required deep attention. Day2. I felt hungover. Hypersensitive to sounds, meaning that my mind would abnormally jolt to a greater sense of attention to a noise than before. The dizziness remained but at a decreased level. Day 3. Almost normal; just slightly tired."

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175 Report
  • Redds
  • October 4, 2020

"I have tried many antidepressants. I love Remeron. I feel happy. Side effect always hunger. But it has done amazing things for me. My family and friends gave noticed. Have been on 30mg for 6 weeks."

10 / 10
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79 Report
  • 81Rob...
  • April 14, 2015

"I started remeron about 2 months ago. For my severe depression.. And anxiety and severe insomnia.. The first night taking it I slept the best I had In Years! I didn't wake up feeling groggy I actually felt better sleep wise I still felt very depressed and that continued for a few week to the point I tried to commit suicide and then I new I needed help.. The upped my remeron to 45 mg at bedtime I've been on 45 mg for a week and I've noticed a big change I feel normal again.. I give remeron a 10 it improved my life a great deal!!!"

10 / 10
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142 Report
  • Khale...
  • Taken for 6 months to 1 year
  • June 10, 2019

"I have MDD, anxiety disorder, panic attacks, and ASD (autism spectrum disorder). I was put on a combination of 7.5 mg Remeron and 100 mg of Pristiq. Within a few weeks, I stopped having panic attacks and I had no more depression. I am so grateful my doctor tried these drugs, it literally saved my life. Before my life was hell and I literally wanted to die. Now I am happy 99% of the time, and I can't remember the last time I cried. The only problem is I am constantly hungry and I have gained 40 pounds in less than a year."

8 / 10
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85 Report
  • xyz
  • September 16, 2014

"I had been taking Restoril for sleep for several years. I found that my level of depression was worsening over time and I had to take more and more to sleep. Finally, I decided that I needed to get off of the Restoril. My doctor prescribed Remeron. I have been taking it for several weeks now and find that my mood has improved as well as my sleep. I am down to 1/2 of the Restoril I was taking before and hopefully may be able to discontinue it. The only downside of Remeron is that my appetite has increased, which is not good for me. Otherwise, I would have rated this as a 10."

8 / 10
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134 Report
  • Nic
  • Taken for less than 1 month
  • April 10, 2020

"I've been dealing with a lot of family issues plus I suffer from MDD and GAD, anyway I believe I also have PTSD and I was stuck on repeat in my mind and could not stop reliving a past "argument" had Iwith my family. I took 15mg last night and already the obsessive thoughts have diminished. I also have subconscience fears of being poisoned. Those have also diminished since yesterday. Hope it continues I just worry about weight gain but if my mind isn't occupied with all the rubbish I can focus on exercise."

10 / 10
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66 Report
  • Fred
  • Taken for 6 months to 1 year
  • September 21, 2019

"I have been giving Remeron to my wife (79) who has been diagnosed with advanced dementia. She sometimes is completely confused and becomes even hostile towards me, her husband of 50 years. I have experimented with various doses of Remeron and found out that giving her 15mg doses three times a day is effective and usually keeps her in a reasonable to good mood. In the evening her anxiety comes back about our cats who are used to go outside. I give her a small alcoholic drink (Irish Cream) which has a very beneficial effect on her. Remeron does not seem to interact negatively with alcohol. One hour before bedtime I give her 10 mg of Melatonin. She sleeps very well. I have found that 15 mg of Remeron in the morning, 15 to 30 mg at 2 pm and sometimes another 15 mg in the evening is a very good combination. I know that one should not give more than 45 mg a day, but sometimes and additional dose at night is necessary."

9 / 10
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68 Report
  • Saved...
  • June 1, 2017

"This drug saved my life. I never thought I'd say that but due to a health issue I have had chronic tension headaches that have now disappeared! Oh and my depression and anxiety are gone on this. I'm able to feel blissful. I'm able to handle tough situations. I'm able to live. Give it time to work cause it could make your life so much better."

10 / 10
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89 Report
  • Trust...
  • Taken for 2 to 5 years
  • February 26, 2018

"Literally a life saver. I have been on every antidepressant known to man and I thought they were all a joke, they never worked. I ended up in behavioral health facility for 2 weeks because of a major depressive episode and constant thought of suicide. They gave me this medication and I stuck with it. Initially it will make you sleepy and crave food like crazy. You will also have crazy dreams. This will pass in time. I haven’t fallen into a depression in over 3 years now , which is a record. I have recently lost my job, because of a different medical condition. I am on food stamps and might have to sell my home, but amazingly it’s no big deal to me. Remeron and other forms of therapy have changed my whole outlook on life. If anyone has tried every medication and it hasn’t worked give this one a try. Only downside at this point I can think of is, sometimes when you want to feel down or depressed ( I know it sounds weird) you are not able to."

9 / 10
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77 Report
  • 1234
  • Taken for 1 to 6 months
  • May 24, 2020

"I gained 25 lbs in 6 weeks on Remeron. I was 125lb when I started the medication and now I’m bordering on overweight. Luckily when I stopped the medication the weight gain stopped. It helped slightly with my chronic migraines and did not make me sleepy. I feel it did improve my quality of sleep somewhat, but not enough to continue gaining weight at that rate. I did exercise and watch what I ate but it just made me too hungry. It had no effect on my depression unfortunately, and I feel much worse about myself after gaining all that weight. Ketamine therapy has been the only antidepressant to work for me yet."

4 / 10
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52 Report
  • Kay
  • Taken for 6 months to 1 year
  • July 7, 2018

"I love love love Remeron. I have been severely depressed for more than a decade. I was on bupriopion before, but then had a seizure on it and could no longer continue. I had not taken any helpful medication for years after that. I told my doctor my problems and with the things that I was looking to have alleviated, he recommended Remeron. I have had extreme appetite suppression for a long time as well due to my depression, and I needed a medication to increase my appetite. I was having trouble sleeping due to overthinking at night. I had a lot of ideation. Remeron helped me with all of these symptoms. It helps me eat like a normal person would. It is quite sedative, so it helps with sleep, which is super important for depression, to get enough. And it helped overall with mood. A good one!"

10 / 10
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68 Report
  • Anony...
  • Taken for 1 to 6 months
  • December 29, 2015

"Having failed most SSRI's Remeron was a real surprise. It calmed me, helped me sleep, helped me focus but most importantly had almost no side effects. My appetite went crazy the first week but mellowed out afterwards. I get pretty drowsy about an hour after taking it, so I only take it at bedtime. I had to drop from 45 mg to 30 mg due to it amping me up rather than sedating. Works fine, no tolerance type effects unlike Z-drugs."

8 / 10
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81 Report
  • Weight...
  • Taken for less than 1 month
  • December 1, 2023

"Gained 20+ pounds in a month on Remeron. I work out every day and always maintain a calorie deficit, but still excessively gained weight. I took a DNA test, and it turns out I'm not compatible with this medication and experienced significant symptoms. I would suggest to everyone to get a DNA test to see which medications will or will not work for you."

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7 Report
  • Vinyl...
  • Taken for 1 to 2 years
  • May 15, 2015

"This is perfect for sleep at 7.5 or less. Get to sleep easily, with no worrisome thoughts before bed. I was taking it for depression after a no-go with Prozac. I couldn't handle the fatigue at therapeutic dose and now I use Wellbutrin XL 300 in morning and Remeron 7.5 at bed. I take the wellbutrin at 6am then go back to bed. When I get up at 8, I already have a lift from the Wellbutrin, one cup of coffee and absolutely no fatigue. Happy, less anxious, lost a few pounds and no sexual problems. I love this combination, and don't feel a need to change or add anything. I am curious how a higher dose of Remeron would be now, but I would hate to lose the fabulous sleep effect I get now. I am guaranteed to sleep within 30 mins. Great meds!"

5 / 10
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81 Report
  • medta...
  • September 7, 2018

"I have taken this med for over 2 years. I've been suffering from insomnia, anxiety, and depression my whole life. I found that nothing that could help. Every night I tossed and turned, waking up every 2 hours. The first night I took this, like magic, I slept a whole night without waking up. And every night since then it has worked. However, BEWARE, it will make you binge eat. You have NO control over it. Studies say weight gain from this med only affects like 15% of people. Use look at the reviews on here and across the internet–it's more like 90%. I've always been skinny and I put on 14 pounds within a month of starting it. I quit for a week, which made me extremely depressed and unable to sleep, but I immediately lost all the weight. But I was so depressed, it hurt, so I got back on it. That's why I give this a 7, it's a conundrum, it helps so much with insomnia/depression/anxiety but it makes you FAT. Don't try this med unless you've tried ALL other SSRI's and sleep meds."

7 / 10
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57 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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