The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Review by Anonymous (taken for less than 1 month):
I started taking 20 mg of Latuda in addition to the 900 mg of Lithium that I've been on for over 10 years. Even before the dosage was increased to 40 mg after one week, I noticed a difference in my mood: I became less depressed, wanted to do things like cleaning up, less withdrawn, and the suicidal thoughts disappeared. My sleeping is still not as good as it should be however even with the 25 mg of Seroquel which I sleep very poorly without. I also take Lorazepam as needed for anxiety. I am starting on 80 mg dosage of Latuda shortly, and if all goes well my psych said the Lithium may eventually be dropped.
Latuda has changed my life. I've been treated with everything under the sun since I was 20 years old. Within days of taking the Latuda I felt like a normal person. I don't know if I EVER felt so genuinely happy, light-hearted, motivated to make life changes. It's like a miracle. I don't experience any side effects. I don't feel tremendously hungry either, as I have with other anti psychotics. I only hope it continues to keep my bipolar at bay.
12 users found this comment helpful.
I have been taking Latuda 40mg for a month now. I take it with meals as prescribed but I still feel nauseated. I also take Vistaril which helps with my stomach. I'm bipolar, severely anxious, along with manic depression and I found that out of ALL the meds I've tried over the past 15 years, the combination I'm taking( Vistaril 25mg, Latuda 40mg, Neurontin 300 mg 3 x a day) and Topamax 200mg at night have balanced me out very well. I still have my normal social anxieties and that's something I have to face; not a pill. If you are crying out of control, major mood swings, tired, depressed, then Latuda will help you. If you feel sick to your stomach make sure you eat first, then take it. I don't eat much so that's why mine gets upset.
Absolutely amazing. I have been treated for bipolar/major depression since I was an adolescent. Been on everything under the sun. Some did help-but nothing kept me consistently on an even keel. By the time my Dr gave me samples of Latuda-I had no expectations. For the first time in my adult life I feel normal. My mood is relaxed and happy-I'm sleeping well and no excessive hunger. It does kill your libido-but that is fine with me-I have lost 7 lbs. I started on 40mg and gradually increased to 120mg--I also take 300mg Wellbutrin, 30mg Adderell twice a day and Ativan as needed for anxiety. This medication is life changing.
13 users found this comment helpful.
I was just taken off my previous meds 200 mg Lamictal 30 mg Prozac after a week of involuntary commitment and put on 30/40 mg Latuda one daily at bedtime ..I feel confused ..manic..I'm not completely sure if I'm awake or dreaming most of the time ..I think I was given a placebo ! This crap isn't working for me.I just wanna be normal I have ZERO motivation to do anything
Review by likeaskyscraper (taken for less than 1 month):
So my diagnosis is Bipolar II, Panic Disorder, ADD. Wellbutrin, Lamictal, Xanx, Adderal and now this. Anyone else on so many different things?
I hope I get as lucky as most of you. I've been so low over the last several months, and for the longest time my memory has been just awful.I'm always anxious. Always. I don't expect this medication to fix that, my xanax dose is increasing for that. I'm afraid of weight gain. Wellbutrin has helped me be smallr again and I can eat whatever. I'm not prepared to lose that.
Anyway, I literally just took my first dose of Latuda. (20mg). My psych told me to take it with dinner (I'm taking it at night. So dinner for me :) ). And emphasized how I have to eat half my dinner, take the medicine, and then eat the other half, otherwise it doesn't absorb right. That's his experience with patients any way. But after taking my first dose tonight I felt some nausea and am quite sleepy. I usually lose track of time and stay awake. I'm supposed to be taking ambien nightly for that though. So, I'm taking the ambien at night, 400MG Lamitcal (200mg twice a day), Bupropion[Wellbutrin] 300mg, 30mg Adderall 3 times a day, .5mg xanax 4 times a day, and now the Latuda 20mg. Quite the cocktail, which does make me a bit nervous.
I just started taking Latuda, and have found it makes me very sleepy, I'm wondering if I should take it at night instead of the morning. I was on Wellbutrin but had to be taken off because of extreme anxiety and emotionality.
I have been on Latuda for about 3 years! I was struggling so much with other meds, I was either too tired, wired or depressed! Once I started taking Latuda I was feeling like a new person. I wasn't nervous or scared anymore it saved my life.
24 users found this comment helpful.
Review by Anonymous (taken for 6 months to 1 year):
I have been taking Latuda for 6 months and I am bipolar II. I also am on Wellbutrin. Overall the medication has made me feel better. But I now find that I am suffering from intense anxiety, which is terrible at night. I need to check with my doctor to see if this is a possible side effect.
I've been diagnosed Bipolar II 3 years ago. My depressed periods were much longer than manic ones. My psychiatrist and I tried many medications without success for bipolar depression. In April, he suggested to try Latuda. I was hesitant because we already tried so many medications... but I decided to try. After a week, my depressed symptoms were almost gone. No suicidal thoughts anymore. I was feeling good and was able to determine if my bad feelings were related to my life conditions or to my bipolar condition. I noticed a decreased libido which is my only side effect. This medicine doesn't reduce my anxiety which is still very high.
13 users found this comment helpful.
Review by 2bipolar (taken for 6 months to 1 year):
I have been on multiple medications over 20 years for Bipolar II/ depression. I am currently on Vivactil which has worked in the past but gives a side effect of anxiety. My doctor prescribed Latuda 6 months ago. I sleep well now but still have some anxiety. I have also gained 35 lbs while dieting and working out. I have almost no appetite, but am still gaining weight. Mentally a 9, but cannot continue this because I am getting depressed and having back pain due to the weight gain.
11 users found this comment helpful.
Review by scoop2564 (taken for less than 1 month):
Began taking 20mg Latuda daily about ten days ago. About five days ago I noticed that I'm a lot less anxious - a lot less "catastrophising" - think more clearly, most definitely happier. My appetite is back as well. Suffering far less psychomotor retardation. Actually feel motivated to do some things! Genuine laughter! Also taking Aplenzin 522mg daily. Best I've felt in recent memory. It's my experience only.
29 users found this comment helpful.
Been on 20mg for only 2 weeks now and have noticed a good improvement in my mood. My dose has now been upped to 40 mg once a day. This drug so far has worked better than any antidepressant I have taken (Wellbutrin, Prozac, Effexor XR, Mirtazapine) and better than any antipsychotic I have taken (Zyprexa, Risperidone, Thorazine, Seroquel)
All antipsychotics I have taken so far have caused weight gain EXCEPT THIS ONE. Since taking it for 2 weeks I have LOST 3lbs without any major exercise BUT I have dropped calorie intake to around 1000-1200 a day). The only negative side effect I have had is staying asleep for longer than 5-6 hrs . I also have social anxiety but this medication hasn't helped with that (so far if possible) Highly recommend.
Great! Slow start but kicks in well and helps with high mania and low depression. On 160mg daily. Makes me sleepy at night so I take 1 and 1/2 at night and half in morning. No weight gain. Getting smarter.
23 users found this comment helpful.
Have tried almost everything since being diagnosed with Bipolar Disorder-I 4 years ago. I have been on 40mgs for a month now. Couldn't be happier. My time at work used to drag and make for an even more miserable day, but no longer. Happier thoughts and no mind racing. I have even been able to stop drinking alcohol while on this medicine. I guess it took away the need to self-medicate.
I take this medicine at night with dinner, but after an hour, I can't sit still yet I am very sleepy. I try to sleep but keep having to turn over and over until I fall asleep about 3 hours later. It is a miserable feeling, but sleep very well once I do fall alseep. Small price to pay for feeling so much better. Good luck to all!
35 users found this comment helpful.
I've been struggling with Bipolar I rapid cycling for almost 10 untreated years. I've had really bad depression to the point where I was a afraid to go outside, constant racing thoughts, extreme anxiety. I was sleeping about 3 hours a day at most, and overall I couldn't function at all. I started taking Laduta 20mg for a week then went to 40mg. Soon as I started taking the medicine, I noticed a big difference the next day. I feel more stable, my depression is gone, my anxiety is gone, suicide thoughts gone. I feel like my old self again, where I can function normally and do my everyday stuff on top of being happy. This medicine literally saved my life, and I want to say thank you to the pharmaceutical company that made this.
43 users found this comment helpful.
I have struggled greatly with Bipolar 1 for many years. The past two years have been horrific for me. I am a rapid cycler and it has been so unrelenting that I have had to fight my company through a legal battle to stay employed through the ADA act. Finally I got a new doctor who discontinued me from taking Depakote, Klonopin, Trilifon and Trileptal. He started me on Seroquel XR which was too sedating and now I'm on 40 mg of Latuda. It is wonderful! I have only been on it for 4 days but I feel human again! My appetite is normal and I am losing all my weight from the other meds. I want to socialize and don't feel manic or depressive. So excited.
57 users found this comment helpful.
I've been on this medication for Bipolar I for over a year now. Recently I'm experiencing a bit of bipolar depression with irritability and anxiety, so my doctor has increased the dosage from 40 mg/day to 80, but I'm titrating up at 60 mg this week. I also take Lamotrigine at 75-100 mg/day and I already notice a positive difference, so I think it's fast-acting, which I initially noticed when I was first put on over a year ago (I posted a review here in June 2012). Some minor side effects for me are increased tension in the jaw area.
26 users found this comment helpful.
I started taking 40mg of Latuda alone about 6 weeks ago now. Before that, I was wondering day-to-day if I would make it. Now, aside from being sleepy (that is the biggest side effect, but who doesn't like a nice mid-day nap) I am much more productive, I can get out of bed in the morning, I don't cry uncontrollably, and best of all I don't have those same impulses I did before with shopping and drinking/etc. This really is a miracle in a way. I am on Klonopin now too help sleep, as by the time I go to bed I am all worked up, and they help. They also help for meltdowns although I am going to talk to my psych to see if upping Latuda to 80mg is wise to prevent the meltdowns altogether. 23 and happy now, who would have ever guessed.
32 users found this comment helpful.
I'm very frustrated. I gained so much weight on Seroquel, but felt great. But, I continued to gain weight so switched to Latuda. I'm miserable. I cannot sleep, which of course makes everything worse. I've tried it for a week and am having to switch back now. I hope I can find something eventually that helps me sleep and feel stable, but I don't gain weight.
24 users found this comment helpful.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Data sources include Micromedex™ (updated Nov 25th, 2013), Cerner Multum™ (updated Nov 19th, 2013), Wolters Kluwer™ (updated Dec 1st, 2013) and others. To view content sources and attributions, refer to our editorial policy.