Skip to main content

Keppra User Reviews & Ratings (Page 5)

Keppra has an average rating of 5.5 out of 10 from a total of 297 reviews on Drugs.com. 43% of reviewers reported a positive experience, while 35% reported a negative experience.

Reviews for Keppra

  • carol...
  • Taken for less than 1 month
  • October 15, 2019

For Epilepsy "I was tried on Keppra for a short period as a possible substitute for Dilantin, with the results that; it did control my seizures, but after just two weeks, to borrow from the prescribing information it produced "hostile and aggressive behavior" over even the slightest thing. That was the first time. The second time that I was tried on Keppra, I spent a year on probation for assault. You can guess my opinion It works well for some people, but I fear it's not as safe as the UCB and the FDA claim."

1 / 10
Was this helpful?YesNo
19 Report
  • Anonymous
  • August 19, 2009

For Seizures "This has been my life saver. I've been on this for 7 years or more. I take 4500mg a day along with 600mg Lamictal a day. With each increase I have better control but this knocked me out when increased in larger increments. People say I look tired but I'm so used to it I don't notice. Unfortunately I can't think straight. My reading, comprehension, learning is shot. I've been trying college for years, each increase brings better control. I wish I could stop the medication for a few days to see if there is another world out there but my brain gives me an unfortunate reminder if I'm late."

9 / 10
Was this helpful?YesNo
46 Report
  • Not...
  • Taken for 1 to 6 months
  • May 6, 2018

For Epilepsy "Keppra has made me angry beyond words, impatient, and now I cry all of the time. It has been like watching a train wreck in slow motion and not being able to control it. I feel like I’m going to explode all of the time. There has to be anything better than this."

1 / 10
Was this helpful?YesNo
23 Report

Frequently asked questions

  • Nelle
  • Taken for 5 to 10 years
  • July 7, 2023

For Seizures "I've been on Keppra for about 6 years. Over my lifetime, I've been prone to periodic depression, but this drug brought on almost major depression, especially the last 2 plus years. It also caused a lot of anger, irritability, agitation, impatience, fatigue, and easily brought on crying (I was never a big crier). I'm off it now for only 6 days. Too soon to say, but I do feel a bit calmer. I pray that I improve."

4 / 10
Was this helpful?YesNo
5 Report
  • Nkap
  • Taken for 1 to 2 years
  • October 11, 2015

For Seizures "My fiance (22 yrs old, 130 lbs) has been on Keppra combined with Vimpat for over a year and he has had very bad mood swings, weight loss, anxiety, feelings of hopelessness, depression, and irritability/quick temper. We are trying to find out if there is another medication he can take in combination with these to help combat the side effects, or if someone has found another med that works as well with less severe side effects, seeing this is the only med that has helped his seizures so far (diagnosed at 17) Anyone else with a similar problem, or know what might help?"

4 / 10
Was this helpful?YesNo
29 Report

Are you taking this medicine?

  • amand...
  • September 5, 2009

For Epilepsy "I have been epileptic since I was 5 years old. Now I am 24 years old. I started taking Keppra 2 years ago. In the beginning I was so tired and sleepy- nearly lethargic. That wore off after the first 3 months of being on Keppra. Since I have been on Keppra for over two years I only have had 1 seizure and it was because I missed a dose. But sometimes I think there are other side effects due to Keppra such as lack of concentration, frustruation, irritable and anger."

10 / 10
Was this helpful?YesNo
43 Report
  • Al123...
  • December 14, 2017

For Seizures "My boyfriend is 22 years old and he has never experienced seizures before and then one day at work after not eating or sleeping very well he had a seizure (I forget what kind of seizure) he was rushed to the hospital and they did scans and tried to send him home after 10 mins of leaving the hospital he had another seizure. (just to mention his dads sister has seizures and is on Dilantin) then he had a bunch of CAT scans and an EEG and nothing came back, but now he has to take keppra 4000mg a day for 3 months . He hates it he's very moody now, depressed and he was never like this before. They are going to do a stress test after the 3 months of taking keppra and see if not sleeping and eating right caused abnormal brain waves... I just want this to be over"

4 / 10
Was this helpful?YesNo
23 Report
  • Hailey...
  • November 18, 2007

For Seizures "My daughter is now Six years and she began taking Keppra at age 3 after the severe seizure she had that set her in a coma. She has many behavioral issues with KEPPRA as a down fall but it has maintained control of the gran-mal seizures. So, we give it a chance for the simple reason of the Seizure Free time. "

Was this helpful?YesNo
47 Report
  • Maggie...
  • Taken for 10 years or more
  • August 7, 2014

For Epilepsy "After having seizures for reg every 8 days or so for 55 years on many different anticonvulsants, I was given Keppra, 3000mg daily and for the last 10 years have been free from seizures with no side effects whatever. This medication has changed my life around."

10 / 10
Was this helpful?YesNo
31 Report
  • SJTHO...
  • December 18, 2007

For Seizures "I have been taking Keppera for 6 yrs now. It has helped my gran-mal seiuzres out some what. My doctor has tried me on so many other seizures meds along with this one. I have experince mood changes all kinds of others. but this is the only seizure med that keeps them calm down. Not kept away but calmed down enough to were I can have some what of a life."

Was this helpful?YesNo
45 Report
  • User1...
  • January 17, 2013

For Epilepsy "I had my first seizure when I was 17 (now 23). I always wanted to be on a medications that was safe so one day when I had a family. And now have my family with a healthy boy. I do have to say I was having the depression, I was having dizzy spills and really bad headaches. But I talked to my doctor he lowered my dose and gave me Topamax to take with it. And now my headaches are gone. It is very hard to actually to find the right medication for yourself. I wish you all the best!"

8 / 10
Was this helpful?YesNo
34 Report
  • macey...
  • Taken for 1 to 2 years
  • July 16, 2013

For Epilepsy "I have been on Keppra for 10 months. After 45 years on Dilantin my liver was being poisoned. Dilantin worked as far as controlling seizures. Keppra has worked so far but I have insomnia and no appetite."

8 / 10
Was this helpful?YesNo
33 Report
  • Beccaw
  • Taken for 1 to 2 years
  • October 1, 2018

For Epilepsy "I've been struggling with seizures for seven years. A year and a half ago I was diagnosed with epilepsy and put on keppra. I currently take the almost the max dosage 1,750 mg twice a day. I struggled with grand mal seizures so much before starting keppra. Ever since I started keppra I've only had one grand mal occur a year ago. Although keppra helped my grand mal seizures it didn't prevent my partial seizures or otherwise petit mal seizures. Keppra doesn't react badly with other meds or the body. Overall satisfied with keppra!"

9 / 10
Was this helpful?YesNo
20 Report
  • CKLADY
  • Taken for 1 to 6 months
  • July 22, 2015

For Seizures "I am 37 years old and have had Petit Mal Seizures since I was 2 Years old. My seizures were always controlled on Epival. However, this drug isn't safe during pregnancy so my Dr prescribed me Keppra (500mg) before we staring to try for a baby. Keppra works well for me to control the Petit Mal Seizures. However, it has really bad side effects. It made me extremely tired and quite moody. The worse part about this medication it caused me to have 2 Grand Mal Seizures (10w and 18 w). Before these 2 seizures I have never had a Grand Mal before. I am now off of Keppra and on Lamotrigine and feel great. I have energy and feel like myself again. Best of all no Grand Mal seizures!"

2 / 10
Was this helpful?YesNo
28 Report
  • Anonymous
  • November 9, 2009

For Epilepsy "I took Dilantin for over 20 years and always felt tired. I regularly had seizures 2-3 times a year while taking this medicine. My doctor took me off Dilantin and I transitioned to Levetiracetam (Keppra) because long term use of Dilantin can promote osteoporosis. I have been seizure free ever since and experience no side effects. I also feel more energy as a result of getting off Dilantin."

9 / 10
Was this helpful?YesNo
40 Report
  • KarenHG
  • Taken for 5 to 10 years
  • December 2, 2013

For Seizures "It works most of the time. I developed epilepsy when I was almost 60 years old and the first medication I took gave me horrible headaches. This works, but it also can give me diarhea and when that happens and the medicine doesn't stay in my body long enough to work, I can have mild attacks. Sometimes I have the mild, brief attacks even when the medicine stays in me."

9 / 10
Was this helpful?YesNo
31 Report
  • G Girl
  • June 17, 2008

For Seizures "I have been taking Keppra for 3 years now. I used to take Lamictal and felt crazy during that time. I used to feel sleepy and at first I couldn't wake up in the morning when I started taking Keppra, but now I am happy to be on it. My biggest issue with Keppra is the rising cost and the fact that my body gets used to it so I have to increase my dose."

9 / 10
Was this helpful?YesNo
42 Report
  • Frank
  • Taken for 2 to 5 years
  • April 11, 2020

For Epilepsy "Have been taking Keppra for more than 2 years now and I have never noticed a problem when using. It has completely stopped all of my seizures and gives me no side effects, on top of that, it is a water-soluble drug meaning that I just urinate it out leaving no way for it to do any damage to me. Currently I am on 1500 mg a day or XR medication. On the first time it was prescribed, I never took it for the sole reason that there were so many side effects listed. I had seizures because of my actions. After taking it, I never had a seizure since and feel better than ever. I recommend use of this medication if prescribed!!"

10 / 10
Was this helpful?YesNo
15 Report
  • Angeliz
  • February 16, 2012

For Seizures "In April 2010 I was went into Grand mal seizures which was found to be due to brain cancer. After surgery and sent home I was put on Keppra. As of Feb 2012 I have not had a seizure since but I have found this medicine makes me very tired and I itch all over all the time. I was taking 500mg in the morning and 500 in the evening. Then we changed it to 1000mg in the evening and none in the morning. I find it very hard to get motivated in the mornings. I want to stay in bed and sleep. I take antidepressants but I'm not depressed or crying. I had been and they felt under the circumstances I need to stay on the antidpressant. We tried changing it and I still stayed very tired and that is why I am sure its the Keppra making me so tired. Otherwise Kuddos."

6 / 10
Was this helpful?YesNo
34 Report
  • Bob...
  • June 30, 2011

For Seizures "I have been taking Keppra for 4 years. When I keep up with 2000mg dose daily I rarely have seizures anymore. When I go off the medicines they come back. I would have to say it does the trick with minimal side effects."

10 / 10
Was this helpful?YesNo
35 Report
  • yogiman
  • July 16, 2008

For Seizures "I had brain surgery in December 1996. A tumor was found in the middle of my brain. I had been having blackouts for 16 years before they could find it. I had been on Dilantan before the surgery. It worked but the doctor said Keppra was much better so I was put on Keppra after the operation and haven't had a black out since."

9 / 10
Was this helpful?YesNo
41 Report
  • Outdo...
  • Taken for 1 to 2 years
  • May 4, 2023

For Epilepsy "Avoid. I am 24 years old and I had my first seizure almost two years ago. Had another one a month after that. Grand mals to be exact. Both seizures were very violent, one of the times waking up to blood on my pillow, a black eye, and bit tongue and lips. I was diagnosed having epilepsy. I got prescribed Keppra extended-release. I take 1000mg at night. The side effects are horrible. Horrible mood swings, irritability, anger, rage, the list goes on. It has ruined relationships around me in my life. I am finally switching medication, there are better options out there. I advise you to look at the options. Take it at your own risk."

1 / 10
Was this helpful?YesNo
5 Report
  • Anonymous
  • July 10, 2011

For New Daily Persistent Headache "I have had chronic migraines for 16 years. Because of my hyper-sensitivity to many medications (antidepressants, Topamax, Depakote, and the list keeps going), I had a great deal of trouble finding a preventative medicine that my body could tolerate at a therapeutic dose. Keppra keeps my migraines to a minimum (about 8 per year, which is so much better than the every-other-day I was experiencing). I do have some fatigue and depression as side effects, but they are worth the trade off."

10 / 10
Was this helpful?YesNo
34 Report
  • With...
  • May 18, 2015

For Seizures "I'm 63 now using Keppra (levetiracetam) 500 mg has been a good choice by my neurologist for approximately 5 yrs. I take 750 mg at bed time and it has worked well. My insurance covers Keppra but levetiracetam is more affordable and has worked for me."

Was this helpful?YesNo
26 Report
  • RyanB
  • Taken for 5 to 10 years
  • February 16, 2016

For Seizures "My brother had a tumor 15 yrs ago removed after having a seizure. Takes 1000mg keppra a day. He has mood swings, diarrea if he does eat b4 so, and delusional. Still effective. I started having anxiety attacks n seizures at 24yrs of age. Neurologist perscribed me keppra 500mg daily and 2mg xanax a day when needed, usually I break xanax into pieces as u can because they have little bars to do so. I don't have any side effects besides feeling sleepy at the end of the day. I don't take xanax til after work at the end of the day as xanax does makes me sleepy. Keppra deserves 10 for me. But my brother rates it 7. Every one is different. I know this is for keppra but XANAX is not for anyone a lot of people can't handle the drug and can't control themselves let doc determine."

9 / 10
Was this helpful?YesNo
24 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.