The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Compare all 150 medications used in the treatment of Endometriosis.
Reviews for Lupron Depot to treat Endometriosis
Review by amaya2 (taken for 1 to 6 months):
I started Lupron about a month ago. I started taking it after the doctor told me I had stage 1 endometriosis. About a year before I found out I had PCOS which caused me to gain a lot of weight, about 23lbs. Since I've been on Lupron I've been feeling so much better and I've LOST 7LBS!! The only thing I have been struggling with is the hot flashes. other than that I've been doing very well on the shot.
Review by Anonymous (taken for less than 1 month):
I am only on one week into the Lupron and my pain has begun to, not ease, but not be as sharp as it was at all times. I can finally breathe and think before the next stabbing pains begin. But about two days ago I got mood swings. I seem insane, I'm fine then, I'm screaming. I'm only 17 and this is NOT what I need along with the disease. I hope it gets better for I wont have any friends at the end of the six months.
6 years ago I experienced severe pain caused by ovarian cyst and endometriosis. I eventually had my cyst out but after few months severe pain triggered. I was dying of pain most of the time, until such time I cannot tolerate. August 2008 I was given Lupron Depot. First month was a nightmare for me, I thought I was dying because of extreme bleeding. After that one month my body slowly progress. For three months I had a 3.75mg and after that I was having 11.25mg. I am so relieved that it made me live a normal life. I am pain free and for side effects fortunately not too the extreme. My last shot was done March and supposed to have it last June but due to unavailability of my specialist I am waiting for my next step. So far I am doing fine.
Review by Anonymous (taken for less than 1 month):
I received my first Lupron shot a couple weeks ago. In the past two weeks I have noticed that my pain isn't as bad or as often and it was before the shot. The down side is the mood swings and hot flashes. I thought I had a few weeks before I started experiencing the side effects, but I guess not. I know that the next six months are going to be rough, but the way I see it...I've been suffering for five years already, what is six months of hell to help make it all go away? In my opinion, the Lupron shot is worth it.
2/9/12 I had a full hysterectomy (uterus and cervix removed) due to fibroids. My Dr found endometriosis everywhere. My Dr. put me on Lupron about a month after the surgery and I had my 2nd shot 4/20/12. I got hot flashes right after the first shot but they are really not that bad. Night sweats are more uncomfortable and my joints and muscles are achy and stiff. However, my mood is pretty terrible. I have no patience for anything and feel pretty grumpy most of the time. My pain is lessening but still present. That said, if I can be rid of most of the pain after the 6 months regimen, it will have been worth it!
Got first shot Jan 2012. Side effects night sweats, hot flashes, headache and muscle ache all bearable but hot flashes have interfered with sleep. Just got 2nd shot this wk 4-24-12. Have sore throat and headache, seem to be more agitated and irritable. Hot flashes are a bit worse and headaches are coming back . Overall if this is the jist of side effects all worth it to make sure cancer if spread does not come back. Had hysterectomy Nov 2011 and found cancer in uterus. Drs said it was contained to uterus but for safety precautions put me on Lupron.
Had my first shot about a week ago. I have major pain in my joints (elbows and knees), hot flashes and night sweats. But honestly so far so good. I am no longer feeling the horrible endometriosis pain. Will update more once I'm further in. Plan as of now is to do 6 months of Lupron and see if my Fallopian tubes have less swelling and inflammation as my husband and I would love a baby of our own. Good luck to all. This is not easy. But I am hoping it will be worth it.
I got my first dose a month ago. The main side effects I am experiencing are hot flashes, much decreased appetite (not complaining there) and fatigue. I will take all those any day rather than deal with endometriosis pain. So I am definitely pleased with the Lupron treatment. Its nice to not be in so much pain. I would call off work and stay in bed and cry. So big difference!
I was actually on Lupron Depot for 18 months. My periods stopped within a week and my pain was gone within the first month. I almost didn't go on it because of the horror stories I read online, but I'm glad I did. My skin broke out more than normal, but nothing a little makeup couldn't hide. The hot flashes were intense at first, but slowly started to subside. After six months they completely stopped. I also fully understand night sweats. The side effects were well worth it to me since I no longer have cramps that hurt so bad I pass out. I am also enjoying being period free after never having a regular cycle and being anemic the better part of my life.
10 users found this comment helpful.
I was actually surprised to learn I had stage 4 endometriosis along with 2 endometrioma's and a dermoid cyst. I had always had a poochy gut and severe menstrual cramps since I was 16. I am 27 now and have been pain free for the last 5 months on Lupron Depot. I had a laproscopic cystectomy and a laparotomy this year. I did suffer side effects of hot flashes and mood swings but was prescribed 1mg estrogen daily and I'm pretty much normal! In about 6 weeks I will begin trying to conceive my first child! The Lupron and my Doctor have been a blessing!
I have been receiving Lupron shots since August 2011. December will be shot number five. Within the first two weeks after receiving my first shot, I noticed a huge difference in pain. How awesome! I had been dealing with this pain since 2008. I had exploratory surgery and tried Chinese medicine along with acupuncture and found no relief. Lupron has been the first thing to help me be almost completely pain free. Will post again after 6th injection. I had one huge mood swing after my 1st shot and very little hot flashes. I am not craving chocolate as much but have found myself craving milk (I have always been a milk drinker).
12 users found this comment helpful.
I LOVE LUPRON. I have stage 4 endometriosis and Lupron has been AWESOME. I have only had one side effect hot flashes, which I do not mind at all, they only come twice a day and last for up to 2 minutes. Hopefully me and my husband can have intercourse without pain. I'm 23 years old.
13 users found this comment helpful.
Just finished three shots of Lupron Depot - shots were given in the hip - little to no pain at all. The worst side effect = hot flashes. They were unbearable really, was prescribed the lowest dosage of estrogen medicines for the hot flashes - working great. Doctor not giving any more shots of Lupron until we see how my body reacts to the medicines. I was just prescribed a progesterone as well to balance with the estrogen medicines-to take for a two week period.
I was diagnosed with endometriosis after having a laproscopy. I started the Lupron shots not long after the surgery. While the symptoms seemed to fade, the side effects were terrible. I had unbearable mood swings which caused many problems in the family. The hot flashes were ridiculous. I also ended up gaining about 20 pounds within six months. The pain did subside and I have not had as much pain since I finished the injections 10 months ago.
I just had my 5th shot yesterday. The past few months have been painless in regards to side effects other then night sweats and mood swings. I have not gained any weight and everything seems pretty normal. Once again, other than the mood swings. These are harsh and sometimes I feel like another person has taken over my body and thoughts.
At first I really thought the Lupron treatments where worth it, but now that I have made a trip to the Emergency Room. Well lets just say if you are going to go the route of Lupron you better be single. This drug takes its toll on the family, not just you. Everyone goes throw the mood swings, headaches, blood pressure scares, joint pain, feeling like you are going to pass out. So no taking your kids to school or sporting events. No joining car pools. Don't get to far away from the restroom, urinating more often is not unusual. The things that are the easiest to handle are the hot flashes, night sweats and chills.
14 users found this comment helpful.
I did a 6 month treatment of Lupron and It wasn't that bad. The first couple of months I experienced migraines & hot flashes. For the reminder or the treatment, I continued to experience the hot flases but my mood swings became very uncomfortable for my family, friends, & me. I would one minute be calm & neutral...the next minute I would become mean & hateful. That was never how I was prior to the treatment. However, I completed my treatment in August 2009 and I haven't had any problems with my endometriosis at all. My doctor has now given me the option to either get pregnant or continue with birth control pills until I decide to become pregnant to maintain the endometriosis. I highly recommend this method if you can withstand the side effects.
16 users found this comment helpful.
I was very pleased with my Lupron experience. I was on a six month course and found the first three to four months easy. I did experience hot flashes, mood swings, and slight insomnia. My fifth and sixth month were a little more difficult for me. The hot flashes became a little more apparent, the mood swings more frequent, and my face began to break out. To me, that was the worst. Along with the Lupron, I had a laproscopy 2 months before the medication and I started acupuncture treatments about a month before beginning Lupron which really helped with the side effects. My pain levels before medication were unbearable. I could hardly bring myself to get out of bed. I now notice that my pain level is low if I have any at all.
12 users found this comment helpful.
I just had my second shot 6 days ago. I will admit that my pain from the endo is a great deal better than it was. I was a few days late to get my 2nd shot and could feel the symptoms coming back slowly. The side effects are miserable. I don't want to finish out the treatment. Going for a second opinion. Will be trying estradiol today, for the hot flashes, which have been the worst, at least 3 an hour, and all night long. Haven't had any weight gain so far, weight loss, probably because I am so paranoid about gaining.
I got my first shot almost two weeks ago. I am fat, busty and generally unmotivated. I am a tiny bit nauseous almost all of the time, but it's not bad enough to prevent me from eating. More like an appetite suppressant. Other than that everything seems fine. Although I have stage 4 endometriosis, I didn't have any of the associated symptoms, except for infertility. I guess I'll find out in a year or two if it is worth it.
I took my first injection 4 days ago, but had a migraine that night. Since then I have been crying a lot. I can't believe the side effects have hit me so fast. I have abdominal pain as well but the crying is the worst so far.
22 users found this comment helpful.
I am on my 2nd shot of Lupron and I am not liking the new me. Everyone says after the first 6 weeks it gets better. I don't know if I can take anymore or if anyone else can take my mood swings. I am very hormonal, frustrated all the time and mad about everything. My job and family are suffering. The hot flashes are constant I am miserable. I don't think I will continue with the other shots.
31 users found this comment helpful.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Data sources include Micromedex™ (updated Apr 24th, 2013), Cerner Multum™ (updated Apr 19th, 2013), Wolters Kluwer™ (updated Apr 30th, 2013) and others. To view content sources and attributions, refer to our editorial policy.