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Letrozole User Reviews & Ratings

Brand names: Femara

Letrozole has an average rating of 6.5 out of 10 from a total of 354 reviews on Drugs.com. 48% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Letrozole

  • Lucky...
  • August 31, 2020

For Female Infertility "I have been trying to get pregnant for about 1 year with no luck. Even tried clomid bad it didn't work. My doctor prescribed letrozole day 2-6. I was lucky I got pregnant the same month. I am now 3 months pregnant. I also tested positive a week prior to my expected periods date. Baby dust to all women looking for a baby. I was here reading people's comments before I took letrozole and I got encouraged. May every woman find encouragement in this."

9 / 10
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2103 Report
  • Milie
  • June 29, 2020

For Female Infertility "I suffer with PCOS, my doctor prescribed me with letrozole after using it I took a pregnancy test 2 weeks later it was positive, I’m now 4 weeks pregnant. I’ve been trying to get pregnant for 6yrs now. I’m super happy, please pray for me"

10 / 10
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1639 Report
  • Khuli
  • June 15, 2021

For Female Infertility "Diagnosed with PCOS in Oct 2020 so I heard to go on metformin 850mg for 3 months because I didn't have periods, lucky enough periods came clockwise from Jan 2021. I was then prescribed letrozole 5mg from day 3 to 5, first round nothing, second round I took the same dose again from day 3 to 5 and now am 2 weeks pregnant. Letrozole does work. Please don't lose hope... pray it also works for you."

10 / 10
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675 Report

Frequently asked questions

  • Kay
  • Taken for less than 1 month
  • May 13, 2021

For Female Infertility "I was diagnosed with PCOS. I have irregular periods and did not ovulate. Before I was given Letrozole, my OB recommended me to lose weight to increase my chances, I was 5'1 and 207lb. It took me 5 months after dropping the weight from 207 to 174lb. I finally was prescribed Letrozole. I did 2.5mg from cycle day 2 to cycle day 11. Letrozole did help me ovulate on day 15 (peak) and 16 (high). I got pregnant on my first round of Letrozole. Please don't lose hope, thinking of you all."

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607 Report
  • Pandora
  • Taken for less than 1 month
  • December 11, 2020

For Female Infertility "PCOS for years After a 6cm ovarian cyst removal surgery, I took 2.5mg Letrozole for days 2-6 of period. I had read online that ovulation can be early, but doc advised it can be at any time, really. Pregnant after 1st cycle of letrozole, I pray for everyone to be as lucky and not give up!"

10 / 10
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577 Report

Are you taking this medicine?

  • Blessed...
  • Taken for less than 1 month
  • May 5, 2021

For Female Infertility "Hubby and I started ttc to July 2020 but I wasn’t ovulating and no periods were present. In October 2020 I was prescribed provera to induce a period and clomid to release an egg. That did not work. I went on birth control for 3 months December 2020 to March 2021 to calm my PCOS ovaries. At the beginning of my last birth control induced period I took one round of letrozole and ovulated on the 14/15 of March 2021 and fell pregnant on my first cycle. I am now currently 9 weeks pregnant. Don’t give up hope!"

10 / 10
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513 Report
  • Fazz
  • Taken for less than 1 month
  • January 24, 2020

For Female Infertility "I took letrozole for one month, two a day for 5 days whilst on my period. I am now 4 months pregnant. I was lucky it worked on me straight away. Took the pregnancy test 1 week prior to my next period and still showed pregnant! It does work, you just have to keep trying and praying for the best! Baby dust to everyone trying x"

10 / 10
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597 Report

More FAQ

  • Unknown
  • Taken for less than 1 month
  • September 21, 2021

For Female Infertility "I write this to encourage someone! Reading about your experiences encouraged me too. I was diagnosed with PCOS in August 2021. My periods are so irregular therefore I was put on Medroxyprogesterone/Provera 10mg for 7 days to induce a period. My period started 2 days after stopping it. My Dr prescribed Letrozole 5mg day 2-6 of my cycle. I had a scan on day 13 and I had 2 dominant follicles. On day 14 my Dr gave me an Ovidrel shot to trigger Ovulation. Now I’m 3 weeks pregnant. This was my first cycle of Letrozole. I pray for everyone reading this. Jesus did it for me! He will do it for you too. Remain positive and expect the best."

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369 Report
  • RAano
  • September 30, 2020

For Female Infertility "Diagnosed with PCOS since April 2018. Started Femara from July 2020 along with HCG shots. No luck in first cycle. Miracle happened when took same medication for the second cycle. 5 weeks pregnant now. Just 2 cycles of femara and good news is here. Best wishes to all the ladies."

10 / 10
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466 Report
  • Aimsley
  • Taken for less than 1 month
  • February 6, 2021

For Female Infertility "I was unable to ovulate on my own due to hormonal imbalance/PCOS. After trying to conceive for almost 20 years and doctors not fully addressing my infertility issues I found a doctor that prescribed me Letrozole. I successful ovulated from left ovary on cycle day 17 and then had second successful ovulation from right ovary on cycle day 19. Both were confirmed from a Trans vaginal ultrasound. Here I am several days late but waiting 3 more days until testing for most accurate results. Baby dust to everyone trying! Dosage was 2.5mg starting on cycle day 3. Taken for 5 days."

10 / 10
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334 Report
  • Ubaid...
  • Taken for less than 1 month
  • July 13, 2021

For Female Infertility "I have PCOS since 2018 and even hypothyroidism, I knew I was not ovulating so I went to my gynecologist and discussed my history. She gave me letroz 2.5 tablet from 3rd day of cycle to 7th day and I went for follicle scanning. Doctor said everything is fine but unfortunately there was no pregnancy. Now I'm on my 2nd round of letroz with same dose. I am hoping for the best, I pray for every lady who is trying to get pregnant they wish get fullfilled..!!"

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278 Report
  • Anonymous
  • Taken for 1 to 6 months
  • November 21, 2021

For Female Infertility "everything was normal, regular period proper ovulation still failed to get pregnant we tried for 6 months. I took letrozolr 2.5 mg twice a day from day 3 to 7 and in the same month I got pregnant in fact after 7 weeks I found it is twins and now I am 3 months pregnant. So this medicine works. In my case may be it induced more than one egg. Whatever, but this medicine works for natural conception."

10 / 10
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246 Report
  • Anonymous
  • Taken for 1 to 6 months
  • July 29, 2020

For Female Infertility "I had been trying to get pregnant for 2 years. Did a few rounds of Clomid without results. Got diagnosed with PCOS. Did one round of Letrozole 5 mg and trigger shot without results. For round two my doc upped it to 7.5 mg plus trigger shot and it was successful! Daughter is now 1 year old and we are trying again starting at 7.5 mg. Experiencing depression, fatigue, and intense dreams. Baby dust to all!!"

7 / 10
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311 Report
  • Ishii
  • Taken for 1 to 6 months
  • May 7, 2020

For Female Infertility "Hi there, My fertility doctor prescribed me letrozole 2.5 mg for 3 months. So far I have just completed my first cycle. My periods got delayed by 3 days. I was about to the pregnancy test and saw spotting. Its sad but I am not going to loose hopes. Will try again . Wish me luck "

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284 Report
  • Raj
  • Taken for less than 1 month
  • December 3, 2020

For Female Infertility "I tried letrozole first time and I conceived, I'm now 4 month pregnant - it’s magical for me"

10 / 10
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453 Report
  • Duchess
  • Taken for 1 to 6 months
  • January 29, 2019

For Breast Cancer "I was diagnosed with stage 1 breast cancer in 2015 at age 58. A lumpectomy was performed and I was treated with four weeks of radiation. The cancer was 98% estrogen positive. I began first with Arimidex post op but after a while I experienced severe muscle cramps (which may have been caused by a combination of medication problems at the time) and eventually switched to Letrozole. The cramping that I experience in my legs now is not nearly as severe and is doable. I've been on the Letrozole about a year and a half now. I'm writing because I wanted to let you know that if you are experiencing hair thinning while on Letrozole, I have found that taking a B-complex vitamin pill on a daily basis has been very helpful for me. My hair was thinning, but after about six months of taking a B-complex vitamin pill everyday I noticed that my hair thickened and that it now basically stays in my head. Just wanted to pass this information along."

7 / 10
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335 Report
  • Nicky
  • Taken for 1 to 6 months
  • January 18, 2021

For Female Infertility "I used Femara (letrozole) 2.5mg for cycle day 3-7 for the first month, then the second month 5mg cycle day 3-7, but nothing. Until 3rd month, same dose 5mg cycle day 3-7 I got my first positive! Fingers crossed everything will be okay! Praying for all of you! I was going to stop at the second month, because I did had bad side effects but something told me to keep going!"

10 / 10
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226 Report
  • Anonymous
  • Taken for 1 to 6 months
  • November 7, 2020

For Female Infertility "Has anyone used letrozole for 6 months, ovulated but not conceived?"

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435 Report
  • Rebecca
  • October 1, 2019

For Breast Cancer "I’ve been on Letrozole 4 years. I had a lumpectomy w/ radiation, no chemo. I have severe back, hip and groin pain , muscle fatigue, sleepless nights, exhausting days. I walk like I’m 30 years older than what I am. My pain averages from 5 -9 out of 10. I can’t remember a day where I did not have pain. I have a few good days in between the awful days which gives me false hope. I’ve spent hundreds of dollars ruling out other Disabilities only to hear the same result- your x-rays/CT scans/MRIs are fine. I have no quality of life- I used to be a very fun loving person but rarely smile anymore because of pain . My goal each day is just to get through it. I’ve stayed on letrozole In hopes that my cancer would not return. I have an oncology appointment this week, and I will be talking w/ him about discontinuing Letrozole so I can start living again. My heart goes out to all of you who have to deal with these awful side effects ."

2 / 10
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274 Report
  • Femar...
  • October 8, 2013

Femara (letrozole) for Breast Cancer "I have been on Femara for 9 months. First few months were tolerable, as time progresses, I am miserable. In beginning, I experienced nausea and diarrhea. As this went away, the bone and joint pain began. I would be awakened from my sleep in tears, as my hips would ache just from lying in bed. My hands/fingers hurt to make a fist, or do any type of extended writing. My knees ache horribly. When I get out of bed in the morning, I need to stand still for at least 2 or 3 minutes until I can get my legs to work. Same thing when sitting for any length of time. I am 45 and feel like I am 85. "

1 / 10
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481 Report
  • noosa
  • April 11, 2012

Femara (letrozole) for Breast Cancer "I am 65 and have been on Femara for 2 years. Side effects quite severe. Joint pain, lost libido, dry vagina. However it is what it is and we must continue to take. So, I decided to fight the effect, dry vagina improved with a non hormonal lubricant. For joint pain, fish oil, magnesium, zinc and calcium twice a day, big improvement. Also each morning no matter how stiff you are, go walking, it warms up the joints and gets you going for the rest of the day. I also do weights 3 times a week to increase muscle to protect bones. All have made big a difference. No weight gain. Vitamins have certainly helped keep hair and skin in good condition. Three more years of it so it's best to just keep trying to counteract the negative effects."

5 / 10
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513 Report
  • JPano
  • Taken for less than 1 month
  • September 9, 2020

For Female Infertility "I have PCOS and have struggled with my irregular periods all my life. In 2017 I TTC and used Letrozole for one cycle... 2 pills a day for 5 days and BOOM! Preggo! After trying for 5 years it was a miracle pill! Now I want baby number 2... to my surprise 3 years older and same medication has the opposite effect. February 2020 did Round one, one pill for 5 days. No luck. Then Covid hit! Smh. Started again in Aug 2020 round 2, 2 pills for 5 days. I figured this was the same dosage as baby#1 so it would definitely work and nothing. My heart was broken.. no luck again!? Currently doing round 3. Doctor increased the pills to 3 a day for 5 days.. Getting checked next week and hopefully the trigger shot will help. I can say it works from past experience but I honestly believe age and dosage has a lot to do with it. Wish me luck! And wishing you all The best.. keep your heads up.. it can still happen! -jp"

10 / 10
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191 Report
  • Loving...
  • Taken for 2 to 5 years
  • October 9, 2013

Femara (letrozole) for Breast Cancer "After a lumpectomy for stage 1 Breast Cancer, I was prescribed two other aromatase inhibitors prior to Femara. I had occasional head pain in one spot from all of them. I also had trigger finger and terrible knee pain from Arimidex. My doctor then put me on brand name Femara and the joint pain, head pain, and trigger finger all went away. What is bothering me now is the hair loss (can see my scalp!), memory loss--constantly groping for words. Sometimes I do feel like I'm "foggy" but mostly I just can't remember words. I feel it is getting worse as time goes on and I do not understand why others report the same but there is no mention of this in the patient information leaflet."

8 / 10
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406 Report
  • Sarah
  • Taken for less than 1 month
  • December 27, 2021

Femara (letrozole) for Female Infertility "Had irregular periods and sudden weight gain, when consulted I got to know I have PCOS. I was advised to try for pregnancy as it might get difficult for me to conceive if I delay. I consulted many doctors, different doctors different advises!! I started dieting and exercise but nothing worked! I was then told to start glucophage 500 mg and femara on my periods days 2-5. I had no side effects. With the grace of almighty I conceived that month itself and have twin baby boys now.."

10 / 10
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126 Report
  • Sjano
  • Taken for less than 1 month
  • March 2, 2021

For Female Infertility "I was diagnosed with PCOS 3 months ago after going to a fertility clinic, although I thought I had it when I was admitted to hospital 4 years ago with a cyst, that popped and made me really sick! The doctors just shrugged it off and this happened twice ! I’ve just started take letrozole 5mg day 2-6 and just received my smiley face !! Side effects was bad headaches that I couldn’t shake off and hot sweats, later on before I ovulated I felt like my ovaries were going to pop (google this thinking it was going to happen ) so fingers crossed my next cycle will be the one and We will get our first BFP !!! For those TTC I send lots of baby dust your way, and those that are already there I wish you a happy wonderful pregnancy x"

10 / 10
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157 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.