User Reviews for L-methylfolate

Deplin (l-methylfolate) for Folic Acid Deficiency: Having struggled with depression all my life, I have taken Lexapro & Adderall for 2 years. Was curious if Deplin would do for me what Adderall does: increase drive, initiative, alertness, concentration, mood & sociability. IT DOES! I feel happy, hopeful & alert w/out feeling “sped up” or high! Dr said Adder. depletes folate in brain, so Deplin is important. AMAZING how much better I feel after only 7 days on it (w/ Adder. & Lex.). Have my life-long struggles with depression & ADHD only been fofolate deficiency? Love that Deplin is medical food, not another amphetamine!

Deplin (l-methylfolate) for Depression: I'm 47 and have had serious, treatment resistant depression since my early 20s. Antidepressants have offered me some relief, though it has been far from complete. Although I have remained consistently on antidepressants since Prozac was released, my depression has been bad. I've been muddling along on Pristiq and Welbutrin. Recently my doctor had me on Ritalin as well, to give me the energy just to make it through the day. She put me on Deplin a week ago and its effect on me was felt the next day. After a night of extremely colorful dreams, I woke up feeling great. I took my medicine as usual and it was suddenly as if my brain could feel all the antidepressants for the first time. I spent a trippy weekend, got in touch with my doctor on Monday, immediately discontinued Ritalin. I'm still feeling great, full of energy, and still feeling over medicated. I suspect the next step might be to reduce, if not discontinue, the Pristiq and Welbutrin. This is the first time I've ever actually thought I may have found a "cure" for lifelong depression. It's only been about a week now, but I remain cautiously optimistic.

Deplin (l-methylfolate) for Depression: I have been depressed since 1998, after I had a fall at work, and with problems with the work doctors. My doctor had me try different types of medications, like Prozac, Wellbutrin, Paxil,and Tofranil. Finally the one that helped me was Effexor. At least I thought so. Then the Doctor put me on Deplin and I felt like I hadn't felt in a very long time. That was 8 weeks ago and now I feel great. Deplin has really changed my life. Thank you for letting me share this with you.

Deplin (l-methylfolate) for Depression: No side effects, many more plus/up days than before. Seems the longer I am on the Deplin in conjunction with my antidepressant, the better my moods and overall feeling gets.

Deplin (l-methylfolate) for Borderline Personality Disorder: Deplin has given me my life back. It has enabled me to gain control of my emotional roller coaster, my anger outbursts and become a more down to earth person who is now approachable - when before I wasn't. I was lucky, my therapist recommended me to be tested for MTHFR because I also have Factor V Leiden and MTHFR is found higher in those with Factor V (both are genetic disorders). After my results, she gave me Deplin and the next day I woke up a new person. My husband and family are amazed and I'm now capable of being the wife and mother that I want to be. I am so happy - and so amazed. And I feel WHOLE again.

Deplin (l-methylfolate) for Depression: This has helped better than anything else I have tried.

Deplin (l-methylfolate) for Depression: I have suffered with Major Depressive Disorder, Generalized Anxiety Disorder, and Obsessive Compulsive Disorder for over twenty-years. I have been on many types of anti-depressants with moderate success. I started taking Deplin 7.5mg once a day and I can't believe the results. I feel "normal." My idea of normal is to go through a day without having feelings of hopelessness and wanting to stay out of social situations. I feel great. I started feeling the effects of Deplin on the second day. I am a mental health counselor (graduate student). I have learned how to survive and muddle through all that I want to accomplish in life. Deplin has given me new hope for the future.

Deplin (l-methylfolate) for Depression: Just turned 50 and I've fought with Bipolar Disorder and Depression my entire life. I've been taking 300mg of Lamictal to control mood swings and 1.5mg of Klonopin to treat chronic anxiety. Depression was still so overwhelming that I asked for an anti-depressant. The MD prescribed 200mg of Wellbutrin SR which had a positive effect, yet did not get rid of the underlying thoughts of death and dying; many of you will understand that I'm talking about a coping mechanism not actually wanting harm myself. A pharmacist told me to ask my MD about Deplin and that was the best medical advice I've ever received! I've been taking 15mg daily for over two months and have not felt this "normal" for many years! Thanks for reading my opinion.

Deplin (l-methylfolate) for Depression: I hope this helps to all the depressed people out there. I have been seeing a psychiatrist for drug induced depression. I abused meth, Vicodin, coke, and any other drug you can think of for years and that has left me a basket case. I have tried many antidepressants but I suffer too many adverse reactions for the stronger stuff. I am currently on 300mg Wellbutrin and 15 mg Deplin and I have to say I feel GREAT! However I had taken Wellbutrin/Deplin combo in the past and it stopped working for me after 6 months. The results with the antidepressants were a little funny because I went back to abusing Vicodin. Now I am clean of any drugs and just taking what is prescribed by my doctor. 300mg Wellbutrin and 15 mg Deplin.

Deplin (l-methylfolate) for Depression: I've been on Deplin for 20 days now, along with Zoloft. I had great success with Cymbalta, but it messed badly with my blood pressure (going from 112/65 to 175/100) so I had to go off it. I was put on Zoloft as a stop gap, but have tried it in the past without much success, as with all the others. They say it can take 4-6 weeks before Deplin has its full effect. I'm still hopeful, but I do so wish I'd seen the overnight change like others.

Deplin (l-methylfolate) for Depression: I have had partial response to my antidepressant. I have had a hard time finding one as my chemistry responds unfavorably to many drugs. Deplin was advised by my Doctor who has actually participated in clinical trials. She had seen no adverse effects and thought it would work great for me. On 3rd day I felt like my old self for first time in 1 year. Unfortunately, that night I had auditory hallucinations... first time in my life... and a very restless night. Went off and slept okay. Tried just doing folic acid and Vitamin B6 and had the same response, only worse. Didn't sleep the whole night. Both my Psychiatrist and Psychologist say I am the only person who they have ever seen have a negative reaction. Like I said, I felt great. Good luck.

Deplin (l-methylfolate) for Depression: I have been on Deplin for six days and I am amazed with the change in my emotions and feelings. I take 7.5mg of Deplin and 60 mg of Prozac and I am pleased with my increased defenses to deal with my daily life. I feel like myself again for the first time in 10 yrs. I hope Deplin will continue to provide me with the positive attitude that I am now feeling. I feel like a whole new person.

Deplin (l-methylfolate) for Depression: I am hearted by the 6 reviews. I have just started on Deplin. I have been on Remeron for two years. I cannot tolerate serotonin type medicines such as Prozac, Lexapro. Remeron worked beautifully at first but effects have slowly worn off and my anxiety and mild depression returned. I pray Deplin will work for me and I can regain my enthusiasm and joy in life. I am happy for those of you who have been helped. Wish me luck.

Deplin (l-methylfolate) for Depression: I have very bad treatment resistant depression/anxiety. I was on Prozac for a year and it worked wonders until I had to keep going up in dose and the side effects were just to bad. Since I have been put on Lexapro, Welbutrin, Vyvanse, and Lamictal none worked like the Prozac. Recently my doctor put back on Prozac, 20mg and added 15mg Deplin. Prozac usually take a month or longer to feel the effects, especially on a low dose. After two weeks I felt good already with no side effects! In fact my sex drive has actually increased. 20mg was never enough for me before and with Deplin it's perfect. I'm so happy.

Deplin (l-methylfolate) for Depression: I started taking Deplin yesterday and recently tapered myself off of Cymbalta and Wellbutrin. I still have the Cymbalta withdrawal "brain zaps" but have regained my crying reflex that I lose everytime I get back on medication. I have been pregnant several times and needed to come off all medications for the duration. Today I had more natural energy than I've had in a long time. I had been taking Hydroxycut just to get myself moving and to the gym as I had reached my maximum weight of 188 last week. Now I don't feel like I need it anymore. My OCD is almost non-existent now. I can complete multiple tasks without spending an eternity detailing every aspect of a small task. This is how I feel after day 2, hopeful this will continue.

Deplin (l-methylfolate) for Depression: I've been on Deplin for about a year and it has helped me drastically. I was originally diagnosed with bipolar and later, through blood tests, found out my bipolar was related to a condition known as MTHFR. I am compound heterogenized meaning I have one of each genetic markers which contributes so a multitude of diseases including mental disorders and circulatory conditions because I do not metabolize Folate/folic acid. I was on Lithium for 2 years (with horrible side effects on minimal doses) and since being on 30mg of Deplin plus 5000mcg Methyl B12 I've been taken off the Lithium completely and have normal mood changes.

Deplin (l-methylfolate) for Depression: I just took my second dose of Deplin. I love the fact that there are no side effects. I went all through the day without getting so angry at someone I would get an anxiety attack. It's a start and I'm hoping I can return to my normal self. Wish me luck.

Deplin (l-methylfolate) for Depression: I've been on so many different medications for the past few years. A couple of weeks ago my psychiatrist decided to try Deplin. I can't even begin to explain the change. I haven't felt this normal in five years. I'd forgotten what it was like to not be depressed. This is a miracle medicine.

Deplin (l-methylfolate): I never responded to any medication for anxiety and depression, which was made worse by most medications. Deplin was a miracle for me. I started to use it this summer and my response was immediate. My response seemed to pop out this summer but I learned that some people can have this response and need to lower the dose and start and stop the medication. Also my response could have been do to the Klonopin that I reduced after 20 years of usage. Overall this medicine was a miracle for me..

Deplin (l-methylfolate) for Depression: In about 1 week I noticed drastic change. I was feeling much happy, less mood swings, and even my anxiety had lessened. I like this medication because it's natural and has almost no side effects. I highly recommend it.

Deplin (l-methylfolate) for Depression: I have been on Deplin for over a year now. At first I was on 7.5 mg and that was helpful but when that stopped working the Psych doctor increased the dosage up to 15 mg and it really works. What it does is helps your other antidepressants work better. Deplin will affect each person differently depending on which antidepressant you are taking.

Deplin (l-methylfolate) for Depression: I found the pamphlet for Deplin while sitting in the waiting room. I was very intrigued because all of the adjunct medicines for anti-depressants usually have many side effects. My doctor was skeptical, stating that it was just a vitamin but wrote me a 'script. Effexor is the only one that works for me. I tried Cymbalta for pain issues and spent most of the time in tears. Before my diagnosis, I was constantly suicidal. As of late, my dark moods were back too often. But after 3 days of Deplin, I woke up feeling motivated and hopeful. I am amazed but so grateful.

Deplin (l-methylfolate) for Depression: I have had depression for 8 years and nothing has ever pleased me.. I just had a baby 5 weeks ago and my depression like doubled! I felt so lost and I really thought I was losing my mind!! I just wanted to end my life! I told my OBGYN and he gave me this medicine and I really haven't felt this good in years! It makes me feel relaxed and do nothing but laugh! My mom said she hasn't seen me this way in years! I was pushing my sons dad away because of how I been feeling but I just been so happy around him now! I can handle the baby's crying better and most of all myself! I just feel alive again. Thank you Deplin!

l-methylfolate for Depression: I am a 63 year old man (a psychologist) who has had treatment-resistant depression for many years. In the past ten years I also have had frequent (10-15/month) migraines--migraine and mood disorders often appear together. I started on Deplin 7.5 mg/day along with Zoloft 50 mg./day last month. I had been on Zoloft alone previously with no improvement. After 3-4 weeks of no change in mood or functioning, my psychiatrist increased the Deplin to 15 mg./day and the Zoloft to 75 mg./day (not a high dose). Within a few days, I experienced an increase in energy and sharp decrease in depressed mood--to the point where I'm feeling back to what "normal" was decades ago. I have been through numerous antidepressants and never experienced this.

l-methylfolate for Depression: I have battled depression and anxiety for 15 years and was prescribed Klonopin. Over the years I have remained on Klonopin, in addition to Paxil which was added 6 years ago. I didn't see any significant changes in my depression, but my anxiety was under control. After trying several antidepressants with no significant change in my depressive mood, I was frustrated. My doctor, prescribed Methylfolate and today is my 2nd day taking the medicine. I woke up this morning with hope, energy, and excitement. It has been years since I have felt excited about what a day in my life would unfold, and it happened today. I feel like I am participating in life today as opposed to being a spectator.