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Humulin R U-500 (Concentrated) User Reviews & Ratings

Humulin R U-500 (Concentrated) has an average rating of 5.9 out of 10 from a total of 7 reviews on Drugs.com. 50% of reviewers reported a positive experience, while 25% reported a negative experience.

  • Anonymous
  • Taken for 6 months to 1 year
  • November 11, 2013

For Insulin Resistance Syndrome "HI<I am a 60 yr old female and have been diabetic since my early 20's.I have been on several medications and until this one I couldn't get my blood sugars under control. I am over weight and my body is resistant but 12 units of this drug and my sugars are great.a1c WENT FROM 7.8 TO 6.1"

10 / 10
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22 Report
  • shhtrm
  • March 18, 2023

For Diabetes, Type 2 "I have been on Humulin R U-500 for about 3 months now at 120 units and it has brought my numbers down between 150 to 250 which is better then it was before. I do not like how it makes me feel. After a couple of weeks I started swelling real bad in my arms, hands and legs. Sometimes when I wake up my arms and hands hurt so bad and are so swollen that I can hardly close my hands. I have gained 20 pounds since I have been on it. I have been begging my doctor to change me to something else."

1 / 10
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3 Report
  • Ann
  • Taken for 10 years or more
  • April 19, 2020

For Diabetes, Type 2 "I have been on this insulin for about 3 years. As with everything it works great at first and then seems to go back to having high blood sugars. We are going to try the pump next. I am so insulin resistant that sometimes it can be very depressing. Right now I take Victoza and Lantus with the Humulin. With no diet changes my blood sugars have been hitting the 300's. Unfortunately due to a serious back surgery I can't hardly walk and cannot exercise. I also experience a weight gain on this insulin, So it's a catch 22. Take insulin to lower glucose, gain weight so you have to take more insulin, more weight gain. Yes very disappointing, but not saying this would be ideal for someone else."

4 / 10
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8 Report

Frequently asked questions

  • Momx2G
  • Taken for 1 to 6 months
  • June 29, 2020

For Diabetes, Type 2 "Started taking for a new pregnancy for the first time, it worked well for 1 day, the next day my sugars would not reduce well after a meal, and I watch what I eat like a hawk! Low carb, low starch, higher amounts of protein and still it has not worked in 3 weeks, my numbers easily hit 175 after meals and I’ve checked even 4 hours after and it only reduced to the 140s. Not worth the price if it’s not going to work consistently."

1 / 10
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5 Report
  • chicken...
  • April 14, 2016

For Diabetes, Type 1 "My Diabetes has never been in such good control ever since I started using Humulin R U-500 Insulin. I recently got an insulin pump and this is the insulin that was used. The insurance I have now will not cover any insulin so I had to stop taking Humulin R U-500 due to the fact I cannot afford the out of pocket costs. I am a hard working woman with a good job but because I am not at the poverty level I am unable to get assistance with paying for this insulin. I have been off of this insulin for 2 days and my blood sugars are rising 250-500. I need this insulin and I need help in order to be able to start using it again."

10 / 10
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8 Report

Are you taking this medicine?

  • Swollen
  • Taken for less than 1 month
  • May 26, 2018

For Diabetes, Type 2 "I have just got put on this about 2 weeks ago and come to find out more about it. I had to stop taking it because it caused me to swell up really badly."

5 / 10
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11 Report
  • Cmbsh...
  • Taken for 2 to 5 years
  • January 11, 2017

For Diabetes, Type 2 "This has helped me to control my glucose better than any of the medications that I have tried in the past."

10 / 10
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7 Report
  • Rford
  • February 3, 2016

For Diabetes, Type 1 "Only improvement would be a pen"

10 / 10
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2 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.