The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Review by Katherine R. (taken for 6 months to 1 year):
imipramine for ADHD: I have insomnia and fibromyalgia. The pain from the fibromyalgia is worsened when I can't sleep well. My doctor prescribed this medication to me mainly for better sleep. He said that this medication was one of the first non-stimulant medication for ADHD (which I've been diagnosed with) and so it may help with my ADHD symptoms as well. When I first started taking this I felt nauseated all the time, for about 2 1/2 weeks. Once that passed I felt like I really was sleeping better. About 2 months in I started having vivid hallucinations and 6 months I started having kidney pain and urinary tract problems. I'm now trying to ween myself off of it because sadly the side effects are outweighing the better sleep.
Tofranil (imipramine) for Panic Disorder: Tofranil is THE medicine to take for Panic Disorder. I was diagnosed with Panic Disorder recently, and I was a complete mess. Depressed, suicidal, anxious, the works. My primary care Dr. gave me Xanax. The Xanax helped, but only for short spurts. It also made me more depressed. I was taking up to 3 mg per day, and barely functioning. I got in to see a Psychiatrist, and he is older and more experienced. He immediately knew I had Panic Disorder, and started me on Tofranil. Tofranil absolutely stopped the panic attacks cold. I have been able to cut the Xanax way back, and feel, dare I say, normal. Tofranil is an old medicine, so many docs don't or won't try it. Newer is not always better.
42 users found this comment helpful.
imipramine for Panic Disorder: I started at 25 mg and slowly made my way up to 125mg. It's really not doing much. It has blocked my panic attacks but doesn't seem to do much for everyday anxiety. This is week 5 and I'm thinking of trying a new medication.
The side effects aren't as bad. I didn't have any appetite changes and no sexual side effects (sex drive improved). Only side effect I had was a dry mouth after >100 mg dosages - it is pretty annoying but its not that bad. Other side effect is random episodes of being tired - (again this side effect wasn't that bad).
The only really bad thing I have to say about it is that it didn't really work for my generalized anxiety disorder. It does block panic attacks though! I highly recommend for bad panic attack sufferers.
Tofranil (imipramine) for Panic Disorder: I had my first panic attacks immediately following the birth of my first son 18 years ago when I was 28 years old. The panic attacks were horrific and occurred randomly. I was prescribed a few different medications that weren't successful, but when I was prescribed Imipramine, I felt I had my life back. I doubt that I could have continued to be a primary school teacher without Imipramine. It has really been a miracle medication to me. When doctors hear that I take Imipramine, they usually comment that it is a really old drug that has been around since the 60's. Then they ask if I'd like to try one of the newer drugs. No way! I feel perfect on Imipramine. I can't say enough great things about it.
42 users found this comment helpful.
Tofranil (imipramine) for Panic Disorder: I have suffered with Panic Attacks all my life but went undiagnosed until 1989. I am now 58 and trust me when I tell you that there is no cure. In my initial diagnosis I was started on Tofranil as an inpatient. After my discharge from the hospital I went 5 entire years without having a panic attack. When they resumed I had to be re-hospitalized and it was there I was put on Klonopin, which I have essentially been off of for a year. I am having constant panic attacks. My daughter does not want me to resume Klonopin as when on it I slept all the time.
I did this search to see if Tofranil is still being used for panic disorder and I see that it is. I plan to have my psychiatrist to put me back on it as it really worked.
34 users found this comment helpful.
Tofranil (imipramine) for Depression: I suffered from depression on and off til I was 33. My doctor prescribed a couple medicines without success. Tried Tofranil because my mother took it in the late 1950's. Noticed a gradual improvement over 1 to 4 months with the full effect over a period of about 12 months. Medicine did not work at 100mg so went up to 250mg then 200mg. Some (small price) side effects include dry mouth (Gum, tictac remedy) medicine makes you sleepy about 2 hrs after ingestion. Get ready for a good nights sleep, increased appetite and feeling more relaxed than ever before. I remember the first sign of the Tofranil working was when I went outside one day and the sun seemed so bright and I was happier to be alive. That was 25years ago.
60 users found this comment helpful.
Tofranil (imipramine) for Night Terrors: I had panic attacks (Night Terrors) for over a year or more and had lost hope for medication to help. Since the first night of taking Tofranil, I slept normal without the 3-4 am wake up(night terror) and have been free of them for 12 years without changing my medication. I am so thankful to have finely found and inexpensive medicine that actually worked from the first dose.
26 users found this comment helpful.
Tofranil (imipramine) for Interstitial Cystitis: For 3 years I have been battling bladder cancer. My bladder has shrunk, the pain has been great, the need to urinate is every 15 minutes or so. I have had 9 biopsies, some malignant and more recently 3 in a row benign. I have interstitial cystitis and started using Tofranil 5 months ago. Over the course of those 5 months Tofranil has gradually eliminated the pain and lengthened the time to urinate to once per hour. To me, it is a miracle drug and I continue to take it with no side effects whatsoever.
29 users found this comment helpful.
Tofranil (imipramine) for Panic Disorder: I had suffered with panic attacks since I was around 14 years old. There came a time when I had shock treatments because back in the 60's not much was known about these kinds of illnesses. Later on, I became completely housebound for 8 years. I heard about Tofranil and decided to try it. Within 3 weeks I was able to not only get out of my house but go about 3 blocks away. It takes time, but if it had not been for Tofranil combined with Xanax I would still be home bound. It works, no two ways about it. When nothing else did. The only side effects were sleepiness until it gets into your system (2 weeks for me) and dry mouth. But for me that was nothing to getting my life back.
60 users found this comment helpful.
Tofranil (imipramine) for Depression: At first this medicine seemed great. Was taking it for depression and generalized anxiety disorder. After a week on the lowest dose I started having bad side effects.
I was shaving one morning and noticed my face, lips and arm felt numb. Doctor reduced my dosage to 10mg that worked okay for a week then same side effects.
23 users found this comment helpful.
imipramine for Night Terrors: I take Imipramine for Cataplexy and Night Terrors. For cataplexy, Imipramine is by far the most effective treatment my doctor has tried, as it has eliminated about 70% of the attacks. As for night terrors, they are completely gone. However, if I take a nap during the day, I will have nightmares about half the time. I take 150mg just before bed. The first couple months I was faced with some side effects. If I didn't go to bed right after taking the medicine, I would be in a dazed state and could fall asleep standing up - that is gone. Erectile dysfunction and studdering were also present in the first 90 days or so. Both have disappeared. This is a drug you must give a little time before you see the benefits.
11 users found this comment helpful.
imipramine for Pain: I have been on Imipramine for over 2 years and found it good for pain relief combined with Gabapentin. The only problem I have encountered is weight gain as it tends to increase my appetite.
28 users found this comment helpful.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Data sources include Micromedex™ (updated Nov 25th, 2013), Cerner Multum™ (updated Nov 19th, 2013), Wolters Kluwer™ (updated Dec 1st, 2013) and others. To view content sources and attributions, refer to our editorial policy.