The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Started Enbrel 6 weeks ago and after 2 years of constant pain despite taking a variety of drugs - this week I can actually walk for at least a short distance without crippling pain. The remaining discomfort I think is due to lack of strength from years of forced inactivity which is going to take time to build up but oh - the joy of no pain! So far no side effects and hopefully I can regain my life again.
I have had rheumatoid arthritis for 31 years. During this time, I went through all the medicines given me. They might work somewhat for a few weeks, but then would fail or the side effects were too severe. I have been on "gold" injections (5 years) and Metotroxite, and Predisone for another 5 or 6 years. Eight years ago, I went on Humira for a few months. It was helpful only for a few days and then the rest of the week was too painful. I then switched to Enbrel, at first 25 mg twice a week, and now 50 mg once a week. It has been wonderful - I still have joint soreness if I over-do, and need to take a muscle relaxer at night, but I am so much better. I worry that it may start to be less effective, but so far, I'm loving it
Review by Bill , Illinois (taken for 2 to 5 years):
took Enbrel for 3 years and it took the joint pain away but did not take swelling bags away in wrist, switched to orencia and joint pain came back so once again went back to Enbrel with no joint pain but will have to live with the swelling in wrist, also a big difference in needle pain with Enbrel verses orencia, the orencia needle was nice and sharp with no pain, the Enbrel needles seem to be dull and needs to be sharper like the orencia needles, but at least there's no longer any joint pain, thankful for that.
I am 57 years old. I was diagnosed with rheumatoid arthritis about 3 years ago. During the past 3 years I have taken a variety of medications. I was unable to tolerate Methotrexate. Presently, I take 400 mg of Plaquenil daily, Protonix once daily, and 800-1600 mg of ibuprofen daily. My rheumatologist also prescribes Prednisone tapers for flares. I've been using the Enbrel Autoinjector 50 mg once per week for about 8 weeks. Sadly, I have not experienced any relief of arthritis symptoms. Thankfully, no serious side effects either so I plan to continue with Enbrel for a few more weeks. I'm wondering how long I should wait before giving up.
I started getting sick in August of 2008. After numerous trips to ER's, Dr.'s offices and hospitalizations, I finally got diagnosed with full skeletal rheumatoid arthritis. With it came Fibromyalgia, anemia, insomnia, depression and medicine induced diabetes. Was put on Humira for 2 years with continues Flare ups. Finally was put on Enbrel about 5 months ago and I just now am experiencing less pain and less swelling. I can even jump off the bed first thing in the morning, specially when my dog asked to be taken out. I'm only on 5mg of prednisone now, Enbrel once a week and few intakes of pain meds and muscle relaxants. I'm not sure how long will it work for me but I am thankful for the availability of the medicine and my having good insurance.
After about 7 months of weekly Enbel injections I began to experience severe psychological symptoms. I continued taking Enbrel for about five more months as my doctor didn't believe the symptoms were due to Enbrel. At this point we believed I was in remission and I was off treatment for several months. My side effects disappeared. When I had a flare up I was put back on Enbrel. The psychological side effects came back full force and many doctors saw that it was definitely a side effect of the medicine. Enbrel did wonderful things for my arthritis, but I can't take it again. My doctor has noted these symptoms in other patients.
Enbrel is the first medication I've taken that's actually helped. After taking it for about 10 months with really good results, I had an Achilles tendon repair that was infected with MRSA during rehab. I had to take intravenous antibiotic for 8 weeks and had to go off Enbrel for several months. The pain from the rheumatoid arthtitis came back 10 fold. I'm back on Enbrel now but I find that it wears off by the 5th day, and by the time the week is over I'm in misery with swollen joints. I don't know what I'd do without it - just wish it could work all week.
What can I say?...Enbrel put me in remission. What can be better than that? 8 years of rheumatoid arthritis treatments, some caused inflammation of my kidneys and liver. At the time I started on Enbrel, I was taking 5 different medications. One by one they were eliminated. In the fall of 2012, I caught a bad respiratory infection so I stopped the Enbrel per doctor's instructions and my rheumatoid arthritis did not come back! I hope they do research to determine how often this occurs because I didn't expect remission!
13 users found this comment helpful.
Rheumatoid Arthritis for 22 years. Misdiagnosis when disease presented, 6 years of damage until correct diagnosis. Damage not able to be reversed. Taking ENBREL. I have tried REMICADE, was in trials for ORENCIA, but ENBREL seems to be the one that works better for me.
12 users found this comment helpful.
Started Enbrel 4 months ago, and 100% pain and swelling reduction in a week. No adverse reactions except weight gain. So far, so good! Has made a huge difference in quality of life after 2 years of worsening symptoms at age 45.
16 users found this comment helpful.
I was diagnosed with rheumatoid arthiritis at 22. Enbrel is great, helps a lot. Just like what everyone else says. The real reason for the review is I've seen on here a few people that complain of the cost and the impact it has. No one needs to suffer because of the cost of this medication. There is a program from Pfizer that helps cover the cost of this medication. I don't know how anyone could afford it without the assistance. Look it up at Pfizer. I'm sure most of you know this, but for those who don't, it's more than worth looking into. I pay $10 a month, way better than $2500.
28 users found this comment helpful.
Review by Raft of pills (taken for 5 to 10 years):
On starting the self injection Enbrel, it took six weeks to take the pain away. Enbrel if I had it prescribed twenty years ago, my life would not be wheelchair dependent. My life is anything but painful. I can take part in daily life, enjoy all that can be given.
17 users found this comment helpful.
Review by gratefull grandma (taken for 2 to 5 years):
When I started Enbrel, I had great results. All the staff at Enbrel was and still is a great support team. They have even enrolled me in the sharps container recovery program. The medication itself is amazing. I have had to try other meditation's as my insurance company did not want to pay for it at first but since they were told that I have tried other medications they do pay for it.
14 users found this comment helpful.
Had severe rheumatoid arthritis for 6 years - pain uncontrolled by DMARDs. Prescribed Enbrel and my health improved 85%. Sadly, after using Enbrel successfully for 5 1/2 years, it stopped being as effective. Since tried Humira - didn't work. Now trying Roactemra infusions - some improvement, but lots of side effects. Really miss the quality of life that I had when Enbrel worked for me!
15 users found this comment helpful.
Was diagnosed 3 yrs ago. Thought I'd had a stroke. Couldn't get out of bed on my own. I was reluctant to try Enbrel and decided to go natural with supplements, acupuncture, massage, etc. It worked for about 6 months but when I had flare up decided to try Enbrel. It has been a God send! Been on it over two years with no side effects. I am 62 years old. I went on line to find a good nutritional diet for rheumatoid arthritis. I stay away from dairy, eggs, wheat and some night shade veggies and NO sugar! I believe this staves off any negative side effected Enbrel might have! I take good supplements also. I go to the gym and do light weights 3 times a week and walk the rest of the time. I feel better than before I was diagnosed!
25 users found this comment helpful.
I had terrible rheumatoid arthritis for almost 2 years at a young age. I had it in both my knees and feet and it was going into my right arm. I was so miserable I could barely leave my house for school during the winter. Driving and running were impossible and walking even a short distance was extremely hard without Advil. I started Enbrel 2 weeks before my 18th birthday. The first day I took Enbrel I felt better. I was able to go to my senior prom without pain, it was great! I have been pain FREE with no side effects. I was skeptical at first but I'm SO GLAD I took Enbrel. The shot is painless too! I can't guarantee that it'll work as quick as it did for me, but if you suffer as I did, TAKE ENBREL. It has saved my life and I can finally be a normal teen again.
28 users found this comment helpful.
I have been taking Enbrel for 5 years which is how long I have had rheumatoid arthritis. My original symptoms which were affecting my mobility in the mornings went away in a few weeks. I now go through periods where I do not have any symptoms for months. I have mild stiffness in my feet in the mornings a few days after I experience a period of stress (like working through the night). This medication has changed the course of my life.
18 users found this comment helpful.
I have had rheumatoid arthritis like symptoms for over 2 years with no regular treatment, only occasional prednisone when the symptoms were too severe to bear. After my symptoms seemed like they never went away and I switched doctors, I have just received my 4th dose of Enbrel and immediately felt a difference after the first shot. My coverage does seem to wear off around day 5, but I still feel better than I have felt in 2.5 years. I would recommend this medicine to anyone considering a treatment that won't alter your life's hectic schedule.
24 users found this comment helpful.
I have been taking enbrel for 11 years. I worked great for me until the last year when it gradually stopped working. I did the self injection 2X week. Over the last year the relief subsided 2 days after the shots and then when I took the next 3-4 days from the last it would take 24 hours for the relief to kick in, sometimes no relief. My doctor said he wants me to take Humira but for some reason (irrational or not) I am terrified of changing medicines. I had no side effects from Enbrel except some minor sinus irritation -not infections. I am worried I won't be so lucky with another medicine.
32 users found this comment helpful.
I have been on Plaquenil, methotrexate and several other medicines since I was diagnosed with RA 10 years ago. Nothing seemed to work, had trouble just brushing teeth, brushing hair and the smallest task. Then 3 months ago they put me on Enbrel and boy what a big difference it made. Now I have my life back.
40 users found this comment helpful.
My son is 7 and has been taking Enbrel for a year and a half along with methotrexate. He is doing remarkably! Before the medication he literally had to crawl because the pain was so bad in his ankles. After only one shot of Enbrel he is able to run and play like a normal child! Unbelievable! Thank goodness for Enbrel!
34 users found this comment helpful.
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