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Divigel User Reviews & Ratings

Divigel has an average rating of 7.3 out of 10 from a total of 20 reviews on Drugs.com. 69% of reviewers reported a positive experience, while 25% reported a negative experience.

Condition Avg. Rating Reviews Compare
Postmenopausal Symptoms  
7.3
20 reviews for Postmenopausal Symptoms 157 medications
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Reviews for Divigel

  • Ray
  • August 22, 2020

For Postmenopausal Symptoms "I have used Divigel for many years and am now in my 70's. I am in good condition for my age. I am active taking care of my house and yard, feeling good and sleeping well. My new NP gynecologist says I have to go off the Divigel because I am on Eliquis for AFib and the two are at odds with each other. No other dr has mentioned this. I do not agree with this recommendation and am looking for a new doctor. The dr who prescribed Divigel is retiring. I don't mind taking a lower dose but when everything is doing well WHY do I stop the med that saved my life? I'm mad and I'm not going to take it. Just because you are in your 70's does not mean you should dry up and die. I think that the NP was mad that I looked so good for my age...she was in 60's. So that is my story for now....Divigel has saved my life after a hysterectomy in my 40's with ovaries remaining. I had menstrual problems all of my life until the surgery and subsequent Divigel HRT therapy."

10 / 10
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130 Report
  • Anonymous
  • Taken for less than 1 month
  • May 11, 2012

For Postmenopausal Symptoms "I have gallstones, this medication bypasses the liver because it is topical. I also lost 4 pounds after only a week and a half. I started on the lowest dose. Next week I will try a slightly higher dose, although my night sweats have decreased I am still experiencing some hot flashes. Sleeping through the night is great, no more getting up three times to pee. It works great for vaginal dryness and urethra atrophy. Thanks Divigel!"

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99 Report
  • Stacy...
  • Taken for 1 to 2 years
  • September 23, 2020

For Postmenopausal Symptoms "I started having hot flashes that were preventing me from sleeping and my hair was falling out at my temples and I had had a headache for 6 months. My skin actually hurt. I read the book Estrogen Matters to get ready to talk my doctor into giving me hormones. If your doctor believes the scam Womens Health Initiative study that says HRT is detrimental you would probably find a different doctor. I started out at .5 and felt some relief. I moved quickly up to .75 more relief and now I am at 1mg and I would say I have almost total relief. Hair is even partly coming back. I have a uterus and so I am also taking Progesterone and periods are coming monthly who cares. I sleep again, I have maybe a hot flash a week and they are mild and I plan to take this medication forever."

10 / 10
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39 Report
  • dawnc...
  • Taken for 1 to 6 months
  • August 15, 2012

For Postmenopausal Symptoms "After a surgically induced menopause, the onset on hot flashes and night sweats was so fierce asked my nurse practitioner what works. She mentioned Divigel. I started on the lowest dose and actually felt like myself again within one week of use. Keeping in mind you want to stay on the lowest dose possible, she reminded me that this is to cut down only on the severity of those hot flashes, not get rid of them entirely. I am so happy on this HRT. Just apply to your upper thigh once daily and that's it!"

10 / 10
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69 Report
  • Ketty
  • Taken for 1 to 6 months
  • November 11, 2020

For Postmenopausal Symptoms "I have been taking Divigel .5 for 6 weeks and 100 mg progesterone pill and my mind has cleared magically. However, I have gained 3 lbs and my breast got bigger as well as my stomach. It is very upsetting because I have been 127 lbs all my life. Some one has experience the same?"

8 / 10
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22 Report

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  • LisaR...
  • Taken for less than 1 month
  • November 13, 2018

For Postmenopausal Symptoms "Taking .25mg 1/x daily. Thought I could get through radical hysterectomy without HRT and suffered 8 months with minor symptoms as hot flashes, but most significant was major depression. Mental chemistry balances out within 30/60 minutes of Divigel application. To date not noticing any side effects."

9 / 10
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29 Report
  • maire
  • Taken for 6 months to 1 year
  • December 11, 2020

For Postmenopausal Symptoms "Started pre menopause in my late 40s now I'm 53 years ,Was running 2 businesses on 4 hours sleep a night , sweating and hot flushes, electric fan on all night, just couldn't take anymore. I was taking natural medication from a health shop which wasn't working anymore. My GP put me on Divigel , started on a low dose, I'm now on 0.1% x 2 everyday. My GP also put a mirena coil in so to balance my hormones, no more periods, no more hot flushes or sweats, I've loads of energy, couldn't be happier. I also get a yearly breast check, scan, smear and ultra scan the full works, my doctor is a cancer patient shes all about quailty of life , I've put 6lbs on but that could also be down to my chocolate cravings. I'm now a nicer person ."

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18 Report
  • Marsha
  • Taken for 1 to 2 years
  • June 13, 2018

For Postmenopausal Symptoms "I was having severe perimenopausal symptoms and my doctor gave me Divigel and within 2 days every symptom was gone. It's a life saver. I then had a total hysterectomy Ovaries included and had 1 hot flash cause I forgot to use it for 2 days after surgery and haven't had another symptom since and I make sure not to forget again. I take 1.25mg and it's the greatest thing ever. No side effects at all. Love it!!!"

10 / 10
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26 Report
  • Bella
  • Taken for 1 to 6 months
  • November 13, 2019

For Postmenopausal Symptoms "My doctor recently took me off Premarin because I had been on that medicine for several years because of possible heart conditions that may occur. My doctor suggested Divigel. I have been using this medicine for almost two months and the hot flashes are terrible. I cannot sleep at night and constantly turning on a fan. How long should it take before my hot flashes get better? I don’t know what to do. Thanks"

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20 Report
  • Anonymous
  • May 20, 2019

For Postmenopausal Symptoms "I have been taking DiviGel for about 8 years now. In my late 30s I started having seemingly never-ending periods with bleeding every day for months varying from light to scary heavy flooding. Prior to DiviGel, my ObGyn had me try a number of other prescriptions, some that made things worse. DiviGel was a lifesaver! It cleared up the problem completely and almost immediately gave me normal periods again. A few years later, I added an IUD to provide the progesterone needed to counter the estrogen in Divigel. Now I'm period-free and loving it. Not surprisingly, as our US health care continues to deteriorate, especially in the area of women's health, Divigel was removed as a covered medication by my insurance. I continue to get it by now get it through Canada. They are great to work with and they are TONS cheaper than US pricing. I couldn't see myself going without my Divigel. Without it, I would have opted for a hysterectomy years ago, and Divigel helped prevent that."

9 / 10
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21 Report
  • DElise
  • Taken for less than 1 month
  • July 26, 2022

For Postmenopausal Symptoms "VERY difficult to manage if you want to use smaller amounts than prescribed or to divide up a dose into 2 parts (I metabolize the estrogen very fast so twice daily minimum is best for me). Good for hot flashes BUT.. will echo a few people who noticed increased abdominal pain and back pain. I have connective tissue problems and since I started using divigel consistently twice a day (but still below what was prescribed) the pain is brutal. PLUS, gained almost 10 pounds in a week. NO other changes etc that would have caused the weight gain."

3 / 10
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8 Report
  • Bren
  • Taken for 2 to 5 years
  • July 31, 2019

For Postmenopausal Symptoms "This medication was helping me with my perimenopause problems. I have terrible hot flashes. Divigel lessens the hot flashes and help me to sleep better. By my surprise went to get it today and the price was almost the doubled I was so mad. I cannot afford it, and I have medical insurance. I guess I have to get other type of medication to help me with my hot flashes. I'm not happy at all."

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13 Report
  • Becca...
  • Taken for less than 1 month
  • March 20, 2016

For Postmenopausal Symptoms "I used Divigel for a few weeks. I've been having pre menopause symptoms. I had a hysterectomy but still have my ovaries. During this time I started having severe stomach pains and my ovaries hurt. The doctor performed a ultrasound. I couldn't believe the pain. The doctor told me that I may need my ovaries removed. I decided to stop using Divigel and the pain stopped. I wouldn't recommend this medication."

1 / 10
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18 Report
  • Anonymous
  • Taken for 2 to 5 years
  • December 29, 2021

For Postmenopausal Symptoms "I sometimes have difficulty adjusting the amount of product to apply. I find the patches a more even method. Several times I have gotten so low I can barely function. The best was Estraderm patches by Novartis, which were discontinued. I used these for 23 years and no issues. I haven’t found a similar patch replacement. Different types of Estrogen are used for different products, with different types of effects. It can be frustrating trying these different products. Divigel is the closest to Estraderm, but the uneven application is tricky to control."

8 / 10
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7 Report
  • Sophie
  • Taken for 1 to 6 months
  • February 11, 2021

For Postmenopausal Symptoms "I've been on 0.75 Divigel (and Prometrium 100mg pill) every day for 5 months to managing debilitating symptoms. Divigel, although super expensive even with insurance, works way better than other transdermal estradiol options I've tried including cream that didn't work, patches that didn't stay on and caused allergic reaction from adhesive. I prefer topical estradiol options to try to avoid liver/gall bladder issues as much as possible. While 0.75mg Divi has stopped hot flashes, I will try 1.0mg to see if I can get it to help my hair loss, insomnia and brain fog."

7 / 10
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8 Report
  • Dirt
  • May 17, 2020

For Postmenopausal Symptoms "This Divigel is good BUT I began experiencing a smothering feeling. My sinuses became extremely bad. Drainage was thick from throat to stomach. My chest felt like an elephant was standing on it. It will give tremendous relief with hot flashes. I’d rate it 10+. My experience with side effects if nothing changes -4."

10 / 10
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8 Report
  • Kate
  • Taken for less than 1 month
  • April 6, 2021

For Postmenopausal Symptoms "I have Premature ovarian failure and it is just 2 days I been using Divigel. After I apply it remains sticky and doesn’t dry completely and when I wear my boxer it sticks to it , does any one else has similar problem. My vaginal burning has worsened I was using Vivelle dot patch before but that was not providing enough estrogen."

1 / 10
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2 Report
  • Hel
  • February 10, 2015

For Postmenopausal Symptoms "Hysterectomy at 26. I've been on HRT for 30 years and medications available have changed with time. This is the best I've tried so far."

10 / 10
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79 Report
  • Penny
  • Taken for 2 to 5 years
  • June 11, 2019

For Postmenopausal Symptoms "I am post menopause and Divigel has significantly improved my memory - far more than a pill form of estrogen."

10 / 10
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21 Report
  • Cara
  • Taken for 1 to 2 years
  • September 4, 2021

For Postmenopausal Symptoms "Had total hysterectomy in 2019 - ZERO breast cancer in my family - was just diagnosed with breast cancer last week - 100% estrogen 4% progesterone based .. really ?"

1 / 10
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4 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.