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User Reviews for Estradiol

Also known as: Estrace Vaginal Cream, Estring, Vagifem

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Estradiol.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Atrophic Vaginitis 55 reviews 49 medications
   
7.4
Atrophic Urethritis 9 reviews 44 medications
   
5.9
Summary of Estradiol reviews 64 reviews 6.6

Reviews for Estradiol

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Estrace Vaginal Cream (estradiol) for Atrophic Urethritis: "I have been using Estrace cream for 11 years and it's been working. I use about 1/3 applicator every 5 or 6 days. Suddenly, it stopped working. I don't have a bladder infection, I already went through yeast infection treatment both Diflucan and vaginal creams, and my vagina still burns. The Estrace cream relieves it, but only for about 6 or 10 hours. I am 70 and not sexually active. I know years ago the urologist said everything look kind of shriveled up and dry down there. Could the hormone cream just not work anymore? Now what do I do?"

DeDe126 April 23, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "Very sexually active until severe abrupt menopausal symptoms at 55. AV symptoms the most bothersome as overnight I shrunk up, dried up, itched, burned and tore. Intercourse was out of the question. Dr. gave me a sample of Estrace Vaginal cream. I admit I was afraid to use it and had little faith that it would help so I used only a pearl size amount on clean dry skin every night for 2 weeks. That ammt. Is sufficient to cover all the external parts and more, it emulsifies. I am COMPLETELY healed as far as pain with intercourse and also pain upon urination. It was a MIRACLE for me. Side note: If you stop using it (3X a week after the initial 2wk nightly use) you'll be back at square 1. I give Estrace a 10+ rating C: A tube lasted 6 months"

   
10

Sexpert March 30, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "Someone replied to my first response that I need to wait 6 months. Well its been way over 2 years now, and I am still tearing and having that stinging feeling. I use 100% organic coconut oil for a lube, as my OBGYN said to try that too. I have no side effects from the coconut oil. I used both and then after "enduring" sex, I was left with a couple of tears that were bleeding and stinging. I am going to call her back and tell her I need extra strength. Even after the 1 mg amount, bathing the walls of my vagina, its still not enough. I am only 55, and did not think, this was going to be the end of me. My husband is 13 years older than me, and I am the one that has to turn him away because I am not healed enough to try again"

   
5.0

I need extra strength! (taken for 2 to 5 years) March 19, 2016

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Estring (estradiol) for Atrophic Urethritis: "I used this for vaginal and urethral atrophy. It worked great and I would still be using it but my job changed insurance and it's not covered. There is a coupon to reduce co-pay to $15.00"

   
10

Anon65P (taken for 1 to 2 years) February 25, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "I have been taking this to see if it will help with my vaginismus, which is where the vaginal clamps down during any sort of penetration due to a trauma. I think it has helped mildly, but not cured my condition - which is not surprising, since it's mostly mental."

   
7.0

Okay Karly (taken for 1 to 6 months) February 25, 2016

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For Atrophic Urethritis: "I went straight to a specialist Dr., a Urologist, because I was having vaginal discomfort that I could not really explain or understand. I am not in menopause yet, I still have my period; however, I was feeling like I had a UTI, but I didn't have a UTI. The Dr. asked what Rx's I'm taking and when I told him Prozac, then he told me that is one of the side effects of Prozac. He warned me of the high cost, unless I went to a specific Pharmacy where it cost @ $20-$25. I have to drive 60 miles to get it, but it saves me @ $175, so, I don't mind the drive. I haven't been on it long, so, I'm not sure how well the cream is going to work."

   
4.0

Butterfly33333 February 23, 2016

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Vagifem (estradiol) for Atrophic Urethritis: "awful leg pain, vaginal burning like on fire, back pain, pounding heart, dry cough, stomach pain and diarrhea"

   
1.0

Joyce 51 February 19, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Urethritis: "My urologist has just put me on the cream 3 times a week for preventing uti's. I just started using it so not sure if it will help with this but I pray that it does because the past year I have had one UTI after another and I am tired if being on antibiotics all the time. The antibiotics are so hard on my gut. Anyways no libido and hopefully that will improve too. So far no bad side effects either so that's good. I will be. 60 in may. I always was very active sexually now I don't even want to be touched and my husband is not happy but understanding. So anyways will report back and hopefully this cream is a miracle worker!"

   
5.0

taragurl February 10, 2016

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Estring (estradiol) for Atrophic Vaginitis: "The estring worked very well for vaginal atrophy and dryness. Intercourse was no longer painful. However, I had it for three months and gained 7 lbs. during that time, (with no other changes to my diet or exercise regime), almost all of it showing up in my belly! I took it out for a few days while waiting to refill the prescription and immediately lost 2 lbs. As soon as I put the new one in, I re-gained the 2 lbs. in a matter of a few days. I'm not sure if I'm going to keep using it. I love the convenience, as I had tried Estrace cream and found it messy and a hassle to remember to use it, and the estring definitely alleviated my symptoms, but I can't stand the weight gain."

   
8.0

Dog Lady February 7, 2016

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Vagifem (estradiol) for Atrophic Vaginitis: "54 and Suffering Severe vaginal dryness took vagifem 10 m for 10 days only had to stop due to severe abdominal pain never again will I take this drug users please beware"

   
1.0

Ginney-t (taken for less than 1 month) February 4, 2016

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Vagifem (estradiol) for Atrophic Vaginitis: "I have only been taking this for a few months, but notice a big difference, I suffered really bad pain during intercourse and this has improved the situation, I also think it has levelled out my menopausal moods. I will be staying on it. I am fortunate to live in Scotland where I do not pay for this medication directly, prescriptions are free."

   
9.0

hellojoanie (taken for 1 to 6 months) February 2, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "Extraordinarily overpriced since it is plant based - which means it is probably just soy. Even with my medicare drug insurance, it was going to be over $200. I called a Pharmacy where I used to get my compounded hormones - $27 plus shipping. Suggest you do too. "

   
7.0

Miriam W (taken for less than 1 month) January 26, 2016

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Estring (estradiol) for Atrophic Vaginitis: "Initially I had stomach pains, like period pains, then I got really bad PMT. When my husband asked if I wanted a cup of tea and my reaction was an extremely agressive 'why' I realised it was time to take out the ring. I thought I might be able to do a week on and a few days off but I got very sore within 36 hours of re insertion. I also put on weight which my osteopath says I can't afford to carry. I had a hysterectomy 20 years ago and now have vaginal atrophy, there seems no other treatment but I would not go back to this ever."

   
1.0

Fed up with estring January 26, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "So - I was prescribed this and was shocked when I went to the pharmacy and she said $135. Dr. never mentioned this. I said "doesn't my insurance pay anything on this?" She checked and said "It's normally $350.00" or something. I was really angry. Angry, embarassed and this whole experience is humiliating to women. Why do I think a prescription of Viagra has a co-pay of like $10?? IT'S TIME TO STOP DISCRIMINATING AGAINST WOMEN. Especially us older women!!! That is ridiculous!!! I did not buy it, I was so angry. I may.... but I doubt it. I was prescribed this with an oral progesterone -- any one have experience with these two items combined? Thanks for letting me air that - take heed, Big Pharma."

twistedK (taken for less than 1 month) January 23, 2016

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Estring (estradiol) for Atrophic Vaginitis: "The estring was my answer to vagina dryness and extremely painful intercourse. And I wasn't even in menopause yet. I also had vuvlydynia causing extremely burn and pain. I had tried the cream, Estrace, but could never keep it up and didn't want to deal with it. Finally my doctor recommended the estring. After 2 or 3 weeks, I was feeling completely normal again. I've been using this for almost 9 months now, and I no longer have any pain, and the vuvlydynia seems to be gone. It's a miracle. I can actually have pain free sex once again."

   
10

jjgibbs (taken for 6 months to 1 year) December 27, 2015

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Estring (estradiol) for Atrophic Vaginitis: "I've been postmenopausal for nearly 7 years. Past the hot flash and insomnia stage. My issue was primarily vaginal dryness and painful intercourse, because the vaginal tissue had lost elasticity. I have used estrogen cream and vagifem. Both worked fine for awhile, but gradually became less effective. My doctor switched me to the Estring and I love it. I'm a little unsure about whether I inserted it correctly, because my husband could feel it. Also, I had a pelvic ultrasound for an unrelated issue and the Estring obstructed the tech's view. I reached down and popped the thing out and put it back when she was done - haha. Now, I do that for relations with my husband, too. I will follow-up with doc about proper placement."

   
9.0

Love It! December 26, 2015

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "Side effects of break through bleeding and little relief from thin tissue does not warrant the cost if over $300 with co-pay of $75. This is price gouging for a cream that should cost no more than $20 at the very most -- and I'm being generous. Over priced meds are out of control. I won't bother using Estrace anymore."

   
4.0

Sharonnothappy22 (taken for 1 to 2 years) December 23, 2015

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "Used as directed and not sure it did much, truthfully. I have been having bio-identical estrogen and testosterone implants and that does seem to be very effective. Also, OTC product called Luvena (Restorative Vaginal Moisturizer, pH balanced) is super effective and doesn't cause the stinging and break through bleeding of Estrace. Luvena is significantly cheaper than insanely over priced Estrace ($300 or a $72 co-pay). Really, Estrace should cost about $15 and not the criminally high price it is Bottom line: Not a fan of Estrace and certainly not worth the $72 co-pay for stinging and bleeding for me at ten years post menopause."

   
5.0

Sharongreen1432 December 20, 2015

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Estring (estradiol) for Atrophic Vaginitis: "Can't really rate Estring properly since my total time using it was about three minutes. It felt awful. Removed it and re-inserted it. Still awful. Looked at pictures . Had it in correctly but to no avail. No way would my husband not feel it. I could feel it just walking about. I am a petite woman so maybe that is a factor. Some type of applicator would be helpful. Rinsed it off and put it away. Maybe I'll try again but I doubt it."

   
1.0

Mammy Bear December 2, 2015

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "I was experiencing very painful intercourse with tearing. I have used this medication exactly 3 times it has improved sex 99% already. Some pain on insurtion, but none during intercourse for the first time in years! I have no doubt it will get better as my body's estrogen levels improve.. So thankful. I am 55 yrs old."

His Wife is back!!! November 15, 2015

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Estring (estradiol) for Atrophic Vaginitis: "I just removed the ring after 3 weeks because after two weeks I started having hot flashes, low back pain and vaginal discharge. It has been 3 days now and the symptoms are abating. I did not like the bloat I was feeling and will go back to the Estrace cream, which is not as convenient but with which I did not have side effects."

   
3.0

anonymous cat (taken for less than 1 month) October 10, 2015

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "I have been using 1mg every night for 12 days and am not sure if I can tolerate my side effect symptoms much longer to see if the cream actually works to diminish extremely painful intercourse due to dryness. I now have very tender breasts, a constant mild headache, and swelling, tenderness, and dryness of the external genitalia almost since the first day that I started using the cream. The only good effect so far is that my libido does seem to be heightened. So now I feel 'sexy' again but can't do anything about it because of all my discomfort! I plan on continuing using the cream at every third day intervals for 2 more weeks to see if my side effects subside. If I am still miserable, I will stop the medication and look for a non prescription vaginal moisturizer as my last hope for a continued sex life."

Notwright October 7, 2015

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Vagifem (estradiol) for Atrophic Vaginitis: "I used Vagifem as prescribed by my Gyn. I used this product as directed for on an off for a period of 2 years. I developed fallopian and ovarian cancer last year. I have had to have a hysterectomy-oophorectomy and excision of tumors. I feel that this was related to my taking the Vagifem even though my Gyn stated that this was a small dose of hormone and would not cause any adverse problems. I have since found that this is not the truth!"

Mary Ann Williams (taken for 2 to 5 years) August 30, 2015

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "I have been using estrace vaginal cream for 8 weeks now, about 2 x a week and it has helped my vaginal dryness and prolapse but I am experiencing side effects, anxiety, bleeding gums, joint and muscle pain, problems with sleep. I don't like this. I am going to look for a more natural estrogen."

   
5.0

SheMac August 9, 2015

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "I started using Estrace two years ago after major perimenopause symptoms. Around this time my periods stopped and I did find quite a bit of relief from vaginal and urethral pain and dryness as well as frequent urination and burning. Have gotten along fairly well with several short flareups until recently when I have had a return of my symptoms even though I am still using the Estrace. Any suggestions or experience with this?"

   
9.0

Cindy P July 3, 2015

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