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Replens User Reviews & Ratings

Replens has an average rating of 2.8 out of 10 from a total of 137 reviews on Drugs.com. 15% of reviewers reported a positive experience, while 75% reported a negative experience.

Condition Avg. Rating Reviews Compare
Vaginal Dryness  
2.8
137 reviews for Vaginal Dryness 21 medications
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Reviews for Replens

  • Janet
  • Taken for less than 1 month
  • October 25, 2020

For Vaginal Dryness "I am on my 3rd use of Replins, after going to the bathroom and wiping there were white chunks, so I got up close and personally with my magnify mirror, and I was shocked at the amount of white globs all over the outside and especially the inside, bleh! I am 53 and post menopause, the 3rd use was tonight after my shower, and it does kinda still burn a little, but if it is shedding dead skin, is that a good thing? I'm still not sure if I want to continue using it or not."

2 / 10
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107 Report
  • Anonymous
  • Taken for 1 to 6 months
  • September 18, 2020

For Vaginal Dryness "OMG! Why did I not read these reviews first??? Used this product to moisturize the Va-jj and after intercourse, the chalky yeasty looking rubbery substance is BEYOND embarrassing. I mistook it for a yeast infection and even took diflucan and Monistat. I was so fed up I went to gyn who immediately knew exactly what it was. They need to pull it off the shelves."

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95 Report
  • SeaDove
  • Taken for less than 1 month
  • November 12, 2020

For Vaginal Dryness "I was recommended by a Gynaecologist to use this product Replens 2nd time using it I feel dry and clumps of white skin cell or whatever is is have been discharging. I want to know is this safe or a good thing? Adding to my frustration!!!!!"

2 / 10
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87 Report
  • Echo
  • Taken for 1 to 6 months
  • June 8, 2020

For Vaginal Dryness "I started using Replens as my gyno suggested for vaginal dryness/atrophy in March 2020. No negative reaction, at first, with exception to clear discharge. It is now June 2020 and I noticed I've been experiencing slight cramping like I'm going to get a period. I'm in my 60's and post-menapausal. Yesterday, I noticed a brownish discharge and still experiencing slight cramping. Will stop using Replens product immediately! I think further research and investigation into product should be put in place, pronto. Too many women are having too many strange and unexplained reactions to this product. FDA should be alerted - NOW!"

1 / 10
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89 Report
  • She
  • Taken for 1 to 6 months
  • January 28, 2021

For Vaginal Dryness "After using Replens I experienced the white chunky discharge many people are complaining about. But after a few consistent uses I noticed that not only was the discharge turning a very dark brown, but I wasn’t coming out anymore! I had to manually get inside my vagina to pull out days of old, dark, chunky discharge. It had little to no smell to it, but was still very unpleasant to see. There’s no need in shedding dry vaginal tissue of the discharge is just going to stay inside the vagina! Never using it again."

2 / 10
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74 Report

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  • WANDA...
  • Taken for less than 1 month
  • October 7, 2020

For Vaginal Dryness "Severe vaginal dryness after menopause is horrible. The vagina changes can mimic uti. Replens is the only thing that has given me relief. I use it every 3 days at night. If I get dry in between I apply a bit by hand. I would rather feel wet and messy than dry as the dessert. I did have some brownish discharge once after the 1st use but it went away. I recommend because I suffered horribly before I used it."

9 / 10
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76 Report
  • MBano
  • Taken for less than 1 month
  • February 3, 2021

For Vaginal Dryness "Used this twice to avoid estrogen cream and started bleeding after the second application, then copious brown sludge discharge, so far for two days. Don't know if the applicator does the damage or the ingredients, but needless to say it doesn't bode well for the product!"

1 / 10
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58 Report
  • Breast...
  • April 3, 2021

For Vaginal Dryness "Oh how I had wish I had read the reviews here FIRST! I was diagnosed with vaginal atrophy but the doctor recommended Replens. Tried the inserts first, all they did was swell me up with 0 lubrication. External gel-same swelling, but this time horrible burning and pain while urinating. It made me itch and burn like a yeast infection. Inside looked as bad as it felt. Decided to try the lubricant in the little packet that came with the inserts. It helped at first but then-BAM! Soreness, itching and painful urination with swollen labia internal AND external. On a whim I took benadryl thinking this has GOT to be a bad allergic reaction. Benadryl took away the feeling of being on fire down there a little to save my sanity! I'll take dryness over this ANY day! Definitely need to report your reactions to the FDA!"

1 / 10
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54 Report
  • maria
  • Taken for less than 1 month
  • September 20, 2020

For Vaginal Dryness "AVOID. Severe uterus cramping after second dosage (3 days after the first one) with big black lumps and brown blood a few hours later which now is fresh red blood with big lumps in. Currently been going on for 2 days, I hope it will stop or it is the doctor next. Peri menopausal, dry after ovulation hence the recommended cream. Never had any spotting or bleeding between periods this is a reaction to the cream. What have they put in it to cause such a severe reaction?"

1 / 10
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59 Report
  • Chloe...
  • Taken for 1 to 6 months
  • December 1, 2020

For Vaginal Dryness "Helped me with labia minora dermatitis. I’m a female in my 20s and also suffer some vaginal dryness due to medications. This product helped so much in many ways. Seeing all the gross skin cells come out that my vagina wasn’t cleaning out by itself proves that it does a great job at helping the vagina if it’s not properly self cleaning due to dryness or whatever else."

10 / 10
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53 Report
  • Max
  • Taken for less than 1 month
  • September 27, 2020

For Vaginal Dryness "First time user. I just got done inserting Replens and immediately experienced severe burning and redness. 3 days later after cornstarch sitzbaths i called my gynecologist and she said I may be the 1% that is severely allergic to some ingredients in the gel. I am still burning but it is severe when urinating. I now have red irritation on insides of labia If you have any resolution to my pain I would appreciate it."

1 / 10
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54 Report
  • ghost...
  • Taken for 5 to 10 years
  • January 4, 2021

For Vaginal Dryness "Hello, The thick white residue that some ladies talk about in the reviews is the dry skin that this product takes from the lining of you vagina the more that you use it the less comes away. You have to remove it. I have used it for years and it is very messy. I use this ladies Pjur med repair glide FANTASTIC!"

6 / 10
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46 Report
  • Anonymous
  • Taken for less than 1 month
  • August 2, 2020

For Vaginal Dryness "I just hope that someone is reporting these reviews to Replens. I've experienced everything from the chalky substance to a brownish discharge which I believe to be a blood residue. It was a scary experience as opposed to being helpful. Replens, go back to your lab and do something about this please!!"

1 / 10
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49 Report
  • Bunty
  • Taken for less than 1 month
  • April 21, 2019

For Vaginal Dryness "Had vaginal dryness so used this, as the information on the outside seemed ideal. It caused soreness and slight bleeding. Complete waste of time and money. Thank goodness for this forum as I thought it was only me!"

1 / 10
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61 Report
  • Dog...
  • Taken for 2 to 5 years
  • May 2, 2020

For Vaginal Dryness "I’ve used replens for a few years now as was recommended by my gyn. It was a miracle treatment for vaginal dryness. I would get disgusting gray-green discharge that my gyn said was dead cells sloughing off. My current weekly treatments leave me itching and burning which I blamed on too much citrus in my diet. I had switched from the disposable applicators to the reusable. My last dose was uncomfortable with that applicator. The next morning I wiped a good amount of bright red blood which I haven’t had in 20 years! I may have cut myself but am also having low pelvic cramping that I now realize I had with previous applications. After reading other comments I don’t think I have developed a sensitivity inasmuch as they made a change to this product."

1 / 10
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51 Report
  • Jaz
  • Taken for less than 1 month
  • October 4, 2020

For Vaginal Dryness "I have used Replens 3 times. I was crampy first time. Felt like an oncoming UTI after second insert. Then the white wet tissue discharge after the third time. Done... was not cheap, so a waste. Too many ladies seem to be having the same symptoms. Like others, wish I had read these reviews! Just don’t......"

1 / 10
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46 Report
  • Ssvie...
  • Taken for less than 1 month
  • April 16, 2019

For Vaginal Dryness "I bought this product to try for my vaginal dryness. One hour after I used it I started having allot of gooey thick bloody discharge. I had a hysterectomy 15 years ago and I am at the end of my menopause so I am not sure why I have blood stained underwear and this bloody gooey discharge. "

5 / 10
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52 Report
  • Annie...
  • Taken for less than 1 month
  • October 17, 2021

For Vaginal Dryness "Be very wary when using this product. As per many of the ladies on this forum, I have experienced a really bad reaction to this medication and wish I had seen these reviews beforehand. I was diagnosed with severe vaginal atrophy in July and the first round of HRT has not worked yet nor estriol pessaries or cream from the Gyn. The GP recommended Replens. Total disaster - horrible burning and pain while urinating. Already had the start of an UTI which compounded the situation. Inside looked as bad as it felt. Soreness, itching and pain with swollen labia internal AND external. I have also had the white clumpy residue. I wonder if that is related to the cramping. I will never use this again and will need to find out how to report these issues. If this product helps someone, then that’s great but the majority of us are in worst shape from having tried this. If I could rate this 0 or a minus rating I would. This product should be pulled from circulation."

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29 Report
  • Scoop
  • Taken for 1 to 6 months
  • July 25, 2019

For Vaginal Dryness "I've used Replens due to vaginal dryness related to menopause. It has helped with the dryness but awhile after use l've experienced slight vaginal bleeding. Not sure why since l had a hysterectomy three years ago. I will not continue using."

4 / 10
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47 Report
  • Pops
  • Taken for less than 1 month
  • December 7, 2020

For Vaginal Dryness "Works very well for me. Used only 3 times so far. I insert with the long plastic applicator, already set up, just squeeze the cream, I use Thurs am or eve, lasts well, I use once a week, just so I can have comfortable weekend sex! So I use just once a week. I am experiencing an itchy clitorus, feels as if I have thrush, is this common ?"

9 / 10
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35 Report
  • Linn
  • Taken for less than 1 month
  • October 17, 2020

For Vaginal Dryness "So first time buying Replens and first time using this. I too wished I had read reviews. Not even time for my period for two more weeks and I’m cramping like a period is fixing to start. I had string like discharge to now white rubbery like chunks and balls. Yuck! Bad Decision Product isn’t what I had expected at all. Won’t be using again. I tried washing everything out of me but I’m still steadily cramping"

1 / 10
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34 Report
  • mount...
  • Taken for 1 to 6 months
  • April 12, 2020

For Vaginal Dryness "I used replens for 2 months, and initially had no side effects from it, used it for postmenopausal vaginal dryness, recommended by my gyno, last week started to feel like i was going to have a period start, after peeing wiped and saw clear discharge with brown tinge to it. I have to say prior to this for about 2 weeks i was noticing a white type of discharge, no smell, consistency of wet toilet paper which is what I thought it was at first, after reading these reviews and many other I now know it was not that. I have mild cramping like that of a period and am still spotting. Currently it does seem to be subsiding at least I hope so. Stopped using about 5 days ago and really I should have stopped using it when the white stuff appeared. I knew it was the replens that made all this happen. Would not recommend this stuff to anyone."

1 / 10
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37 Report
  • Julie
  • Taken for 1 to 6 months
  • July 21, 2018

"Replens was recommended to me by my gynaecologist for vaginal dryness/atrophy. Although it provided relief, the day after inserting it I developed this very strange white tissue like vaginal discharge together with burning and redness. Doctor said that my symptoms were not from the Replens so I continued on using it but the side effects continued. I have since learned that the tissue discharge is a common side effect for many women."

2 / 10
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44 Report
  • Anonymous
  • Taken for less than 1 month
  • July 2, 2021

For Vaginal Dryness "Omg I wished I read the reviews on here!! I’ve recently used Replens Md cream and didn’t think it was connected…but now after reading the reviews!!! The first time I used this I contracted kidney infection…2 weeks later a uterus infection!! I’m 54 post menopausal tried the cream for dryness and all I got was bad abdominal cramping, swollen abdomen and bleeding! I’ve not bled for 8 years…these side effects need to be on the leaflet inside!!"

1 / 10
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24 Report
  • Lmano
  • Taken for less than 1 month
  • July 31, 2020

For Vaginal Dryness "I tried this product Replens for vag dryness, trying to stay away from hormones. I used it before I went to bed, the next day I felt cramping, no bleeding or discharge yet. I now wish I saw these postings before I bought the product.. I will not use it again."

1 / 10
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29 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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