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Duloxetine for Diabetic Peripheral Neuropathy User Reviews (Page 2)

Brand names: Cymbalta, Drizalma Sprinkle, Irenka

Duloxetine has an average rating of 5.7 out of 10 from a total of 45 reviews for the treatment of Diabetic Peripheral Neuropathy. 51% of reviewers reported a positive experience, while 40% reported a negative experience.

Reviews for Duloxetine

  • hemaro
  • April 6, 2009

Cymbalta (duloxetine) "Cymbalta has been a lifesaver for my Diabetic Neuropathy. In just a few days the pain and discomfort went away. The only problem I am facing with Cymbalta is insomnia even in combination with Xanax 4mg and Vistaril 150mg."

9 / 10
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34 Report
  • No Arm
  • Taken for less than 1 month
  • July 11, 2016

Cymbalta (duloxetine) "I have a amputated left arm I have horrible nerve pain ,the doctor I just saw started me on cymbalta I have only been on it a week and have not noticed any different yet how long does it take for it to work?"

2 / 10
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17 Report
  • kathy...
  • August 6, 2010

Cymbalta (duloxetine) "I was very unsteady on my feet, at first some of the pain was resolved, but it didn't work. Even though my feet were NOT swollen they felt that way, very tight feeling. It felt like I was walking on balloons, terrible feeling and I was afraid to walk with that unsteadiness. Didn't work for me, since then, I have been on many different medications. Neurontin, didn't help, amitriptiline, didn't help, Lyrica, didn't help. I am on nortriptyline now with a pain patch. The fentanyl patch really helps, but I don't want to stay on this forever, so trying different medications. I am only supposed to leave the pain patch on 3 days, and found with the new medication, nortriptyline, I can go 5 days. So I am hopeful here. "

3 / 10
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25 Report

Frequently asked questions

  • Mdog
  • Taken for less than 1 month
  • March 5, 2022

Cymbalta (duloxetine) "My issues are Severe anxiety, severe depression, neuropathy. I had suicidal thoughts with Lexapro so I decided to try Cymbalta. Gave me jaw pain, weird taste and smell when starting it but not bad effects. It helped my crying spells to stop and seemed to slightly increase depression. I was on 30 mg. However it made my panic disorder and anxiety skyrocket. It really helped neuropathy and phantom pains I’ve been having. But the heightened anxiety I couldn’t stand so I had to go off of it. It gave me a weird hypersensitivity feeling."

6 / 10
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5 Report
  • Peter...
  • Taken for less than 1 month
  • October 17, 2017

"Started on 20mg per day increasing after a few weeks. At first I had the expected nausea, dizziness and feeling of being slightly out of it. However I was told to push through and give them “time to settle”. Mistake! My symptoms quickly worsened to hot flushes with profuse sweating and a pounding heartbeat where just being inside the house was way too warm. Then the mental confusion worsened to the point where I couldn’t even work out simple things like how much money to give when I went shopping. I was getting very confused and clumsy, dropping things and tripping over my own feet. Finally I began losing control over my upper body. It would freeze up solid with every muscle rigid and there was nothing I could do to relax."

1 / 10
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6 Report

Are you taking this medicine?

  • Tonywwk
  • March 23, 2012

"I have severe Diabetic Neuropathy to both feet, and Neurotin seemed rather ineffective. The pain was a combination of burning, needles and pins sensation, and severe knife stabbing sensations intermittently to both feet. I started taking Cymbalta over a year ago, and it has significantly reduced the sensations and pain, making them tolerable. I initially noticed a loss of appetite, which was a blessing in disguise for me, and I lost 25 pounds before the anorexia disappeared. I have several severe disorders which require close monitoring of my blood, but overall, Cymbalta has been a God send to me."

8 / 10
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5 Report
  • Matthew...
  • Taken for 1 to 6 months
  • March 7, 2023

"Seems to have been effective in dealing with hand pain and tingling but has caused constant nausea, dry mouth, and diarrhea. Reduced to 48 and 72-hour intervals which deal with nerve pain but always cause side effects."

3 / 10
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0 Report

More FAQ

  • Anonymous
  • September 6, 2010

Cymbalta (duloxetine) "Cymbalta lessens the burning pain in my feet that used to wake me up and keep me awake at night. It often relieves burning pain almost completely."

8 / 10
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79 Report
  • Momma...
  • July 7, 2014

Cymbalta (duloxetine) "Can't live without it"

10 / 10
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54 Report
  • Dunn
  • January 23, 2017

Cymbalta (duloxetine) "I"ve been taking cymbalta for 10 years for neuropathy. I didn't know how effective it was until I decided to stop taking it. My foot felt as if it were in hot coals. I love it."

10 / 10
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43 Report
  • Alfie
  • Taken for 6 months to 1 year
  • July 25, 2019

Cymbalta (duloxetine) "I had frequent 'attacks' of neuropathy pains and after a few months of using Cymbalta, the cycle of attacks drastically reduced."

9 / 10
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29 Report
  • Anne
  • Taken for less than 1 month
  • September 1, 2019

Cymbalta (duloxetine) "Within one week I suffered a reaction to the drug with hives progressing quickly."

1 / 10
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28 Report
  • RobinSS
  • Taken for 2 to 5 years
  • January 2, 2014

Cymbalta (duloxetine) "Increases blood sugars. x 2 higher than when not taking it."

1 / 10
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43 Report
  • Anonymous
  • August 12, 2012

Cymbalta (duloxetine) "Did not work for me. I had nausea, abdominal & stomach pain, loss of appetite. I lost 5 lbs. in less than a week."

1 / 10
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47 Report
  • HAPPY...
  • June 26, 2009

Cymbalta (duloxetine) "Works great on my nerve pains, due to diabetes."

10 / 10
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49 Report
  • No Ni...
  • May 28, 2016

Cymbalta (duloxetine) "Sort of worked but I was sleeping all the time. 12 - 14 hours per day and then could not move the rest of the day. Had to stop after 10 days of being a zombie."

5 / 10
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29 Report
  • Lisa
  • March 7, 2016

Cymbalta (duloxetine) "Made me sick first day nausea , dizzy, vomit, sweating, high blood pressure"

1 / 10
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23 Report
  • Anonymous
  • February 25, 2009

Cymbalta (duloxetine) "Caused me to have serotonin syndrome."

9 / 10
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32 Report
  • Sparky
  • August 8, 2022

Cymbalta (duloxetine) "Cymbalta works for neuropathy"

6 / 10
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3 Report
  • GTano
  • September 20, 2019

"After one week of taking the drug duloxetine I broke out in rash. The medication I was given to heal the rash caused the spots to turn to peeling skin."

1 / 10
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4 Report
  • Rose
  • Taken for 6 months to 1 year
  • January 27, 2022

Cymbalta (duloxetine) "Didn't do anything for pain for me, I might as well have taken an aspirin. It doesn't seem to work for pain for everyone."

1 / 10
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2 Report
  • Josep...
  • Taken for 1 to 6 months
  • June 18, 2014

"Causes erectile dysfunction, and raises blood sugar x 2 times.."

1 / 10
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3 Report
  • Flower
  • Taken for less than 1 month
  • October 15, 2021

"Just wondering how long does this medication last in our bodies after taking one week ?"

4 / 10
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0 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Diabetic Peripheral Neuropathy

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