User Reviews for Doxepin
Also known as: Adapin, Silenor, Sinequan
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Learn more about Doxepin.
Reviews for Doxepin to treat Insomnia
Review by ann702 (taken for less than 1 month):
Silenor (doxepin): Was too sedative and I always woke up tired the next day and it made my heart feel heavy and it felt like it was beating slow.
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October 8, 2014 5:02 PM
Review by zanylisa (taken for 1 to 2 years):
Silenor (doxepin): For as long as I can remember, I have had issues with falling asleep and remaining asleep. This occurred in childhood also. It seems to be a family trait. However, my doctor prescribed Silenor and what a difference this pill makes! To have always had problems sleeping and then suddenly, a pill changes the problem. Over the years I have taken, Lunesta, Ambien, Tylenol PM, Melatonin, Benadryl...all stopped working within a period of 3-5 months. Not so with Silenor. I read some posts stating that Silenor has caused weight gain. I have not noticed such, but I do not keep a weight scale in my house. For the present, I will only say that for a chronic lifetime insomniac, I wish that I had this pill 44 years ago. Age now 49.
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September 8, 2014 6:11 PM
Review by Bccmor:
Silenor (doxepin): I was on zopiclone for about 14 years and was successful in weening myself off but having difficulty sleeping again. Doctor prescribed Silenor 3mg and with directions "take 1 or 2 tablets as needed". I've opted to take 1/2 tablet (1.5 mg) to start. I've been sleeping and feeling rested on awakening. Not sure if it's psychological or not.
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September 8, 2014 12:54 AM
Review by Veronica M:
This medication is the first I've tried for insomnia and it's better than nothing, but there has to be something better. I have problems staying asleep and 80% of the time it helps that, and if I wake up for the bathroom or a snack (okay two snacks), I can fall back asleep quickly. But the weight gain! I had no idea it would cause me to gain so much in a short period. 25 or so pounds in 3 months. I will be looking into Prosom instead and hopefully be able to drop this weight.
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August 22, 2014 2:52 AM
Review by aquabohdi:
I started this medication about 10 days ago. Doxepin, 10mg, has been working more days than not. Like most medicines, the first few days it worked like a charm. I took it and I slept about 5.5 hours straight. Sometimes can go back to sleep for another 1/2 an hour. I do feel a little help in the anxiety category. Not a lot but it does help a bit. The bad thing about this medicine is that you feel very sedated throughout the day. You know you slept because of the vivid dreams and you don't wake up the whole night. Nevertheless, you feel extremely tired the whole day. I wish I didn't have to take medicines. But I rather be feeling sleepy and knowing that I slept as opposed to feeling sleepy due to no sleep.
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August 10, 2014 3:54 AM
Review by Anonymous221098:
I've suffered with insomnia fire several years now. At times sleeping only 1 hour before having to get up to go to work. My Dr. prescribed Silenor but my insurance gave me Doxepin (25mg). Biggest mistake I made was taking right before bed because it doesn't help you fall asleep, only helps you stay asleep. Once I fell asleep, I didn't wake up at all until the following morning. If you have children or anyone else to depend on you for care, I wouldn't recommend it. I was actually awakened by my boys and I felt very drowsy, groggy, and irritable. So much so that I caught myself yelling at my kids. I wasn't able to function 100%. This would ONLY be good if you have nothing to do or no-one to care for the next day.
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June 14, 2014 10:27 AM
Review by Anonymous:
June 12, 2014 2:32 AM
Review by Hot mom (taken for 1 to 6 months):
Silenor (doxepin): I find it works really well keeping me asleep all night, I do have some wild vivid dreams but not that often, only down side for me is I am gaining weight
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June 7, 2014 10:12 PM
Review by AnnieSmith11:
Silenor (doxepin): I couldn't stay asleep, tried Lunesta and Ambien, they had side effects I couldn't tolerate. Sleep center said I had mild apnea and said their monitors showed me sleeping but I felt like I was awake more than they said I was and was literally exhausted every day, felt like I was on the verge of "losing it," crying a lot. Was not sad/depressed--was sleep deprived. Have been taking 2 Silenor a night for 2 years: sleep like a baby, 8 hours required, wake up rested, functioning beautifully--I have my life back.
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May 13, 2014 10:35 AM
Review by No Doze (taken for 1 to 6 months):
Doxepin is great at keeping me asleep. The only major problem is the rapid weight gain. I went from 155lbs to 185lbs in only 2 weeks.
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May 7, 2014 10:29 PM
Review by Post concussion:
Developed acute insomnia immediately following a bad concussion. I would doze off but would wake up within 30 minutes, unable to fall back asleep for hours at a stretch. Tried several sleeping medications (off-label use trazodone, Ambien, melatonin, OTC sleep aids. with no success for several weeks and was getting desperate. A mere 3mg of Doxepin saved my life. I slept for six straight hours the first night and it only got better and better. I take 3mg around 9pm, sleep from 11pm to 6am very reliably and have few side effects besides a small amount of weight gain (about five pounds in my first two weeks) and slight drowsiness in the mornings and mid-afternoons. I'm so grateful to have my sleep back.
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April 24, 2014 7:30 PM
Review by Anonymous (taken for less than 1 month):
Silenor (doxepin): Silenor was a nightmare for me. I stuck with it for about 3 weeks and thought I was going out of my mind. I did not sleep at all for the first 4 days and then the hallucinations began. If I did sleep it was in for about 30 minutes at a time and then the terrible nightmares kept me awake for the rest of the night.
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April 19, 2014 1:48 PM
Review by luckystar89 (taken for less than 1 month):
Silenor (doxepin): I tried this for two weeks and yet I never got to sleep on it. I had to try it for two weeks because otherwise my doctor wouldn't give me anything else.
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April 7, 2014 8:08 PM
Review by KathS (taken for less than 1 month):
First night on 10mg didn't fall asleep until 5:15 am after 4 am popcorn binge. Woke up about 7:30 am. Same on next 3 nights with middle-of-the night coffee-cake, chocolates and even a couple of frozen dinners. Dr. upped to 20mg. Same result. Hardly any sleep, night snacking, and started eating more during the day. People have commented about rapid weight gain. They're right. I gained 8 lbs. the first week! My weight has been pretty consistent by 2-3 lbs. for years. Going back to Ambien!
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February 17, 2014 2:19 PM
Review by Arthur Dent:
I was given doxepin 50mg after a very bad experience using Xanax for insomnia. It works fine for my depression, I have a good energy level during the day, but it doesn't do a thing for my insomnia. I feel that if I can solve my insomnia it would go a long way to helping my depression.
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February 9, 2014 8:05 PM
Review by Krystalp:
I have taken doxepin every day for 29 years. I started taking 75 to 150 mg for depression, but once the depression lifted, I continued taking 10-25 mg a day for insomnia. It has been a lifesaver for me as, since my teens, I have not been able to sleep without a sleep aid, over-the-counter, prescription. Doxepin allows me to fall asleep and stay asleep for 6-8 hours. When I started taking it I gained 10 lbs. in a week and have never lost it. I have dry mouth, but that is an inconvenience that I am willing to put with. I tried to wean myself off once, about 10 years ago, but felt very bad flu-like symptoms so I started taking them again. In the past 5 years so 10mg doesn't always do the job and so I often take 20 mg.
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December 19, 2013 8:34 PM
Review by ToddOne46 (taken for 1 to 6 months):
Silenor (doxepin): I have been taking Silenor every night for 5 months and love it. It doesn't knock me out or make me loopy like Ambien. Silenor just makes me a bit drowsy, but more importantly is that when I wake up in the middle of the night I fall right back to sleep - which is a lifesaver for me. Since it's non-addictive, this is great for just normal calm times in my life, which is 95% of the time. But when I'm stressing out over something and all panicky, then Silenor does practically nothing for me. I have to take Ambien or Ativan during that 1-2 week period I'm stressing.
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December 15, 2013 10:45 PM
Review by Anonymous (taken for less than 1 month):
I've been battling insomnia for almost 4 years. I had tried Ambien but always wound up digging in the fridge at 3am. It made me sleep walk really bad. Now with Doxepin, I'm able to sleep through the night and no digging in the fridge at 3am.
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December 12, 2013 9:12 AM
Review by Anonymous (taken for 1 to 6 months):
This medicine has helped me tremendously! This has been the only medicine that has helped me. The only part I don't like about it is that when I wake up I have a really bad dry mouth. Other than that it is great!
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September 17, 2013 12:58 AM
Review by georgie54 (taken for less than 1 month):
Did not take too long to go to sleep. Had some dreams but not nightmares. Woke with dry mouth and a little groggy. Within an hour of being up, I feel very alert, almost energetic, not sure how to explain it, just overall feel better than I have in weeks. Last night was my first dose of 25 mg. So we will see how it goes, hope I don't gain weight, as I have read about. I have had sleep issues for years and tried everything, hope this continues to work.
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September 5, 2013 9:01 AM
Review by Jabber Wakky:
I've been using doxepin for about 2 years for insomnia. I used to wake every night after 2-3 hours of sleep and then was unable to get back to sleep for 1-2 hours. This has helped tremendously. I now sleep through the night, dream and feel better through the day. If I do wake, I am able to roll over and get back to sleep quickly. I take it just prior to bed, and get about 7 solid hours of sleep. I experience some dry mouth in the morning, but nothing severe, and it can be a bit difficult to get going in the morning. Overall, I'm much better than before.
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August 30, 2013 3:33 PM
Review by Dukemannn:
Silenor (doxepin): Makes you sleep fast, and well.
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June 23, 2013 4:04 PM
Review by 456poohgirl:
I have been taking 25 mg of Doxepin for 17 years, I always could fall asleep, but if I woke up during the night, I couldn't go back to sleep for hours. Doxepin was like a miracle to me, I was never groggy the next morning and it didn't make me sleepy and groggy right after taking it. It just lets me go right back to sleep if I get up to use the bathroom. It still works after all these years, not as well though. I have weaned myself off of it, but I start having hot flashes off and on all day...so I start taking it again. And after being off of it for a few days the sleep problems seem to be back...so I may be on this for the rest of my life. I have recommended this to several friends and it has also helped them.
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June 19, 2013 12:32 AM
Review by jmmh:
This medication knocked me out every night and so it was great to catch up on years of sleep debt. Overall, a very positive experience. However, like other users, I slowly gained 10-20 pounds over the course of taking doxepin. I stopped taking it in the last couple of months, and suddenly, my appetite significantly decreased and weight just started dropping off. I had no idea that the medication caused this increased appetite/weight gain. Honestly I thought I was just growing older and my metabolism was changing. I'm glad I took this medication for insomnia, and also that the side effect of weight gain faded away as soon as I stopped taking it. Overall, the value of the sleep I gained far outweighed the con of the weight I gained.
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May 23, 2013 7:23 AM
Review by Good to know (taken for 1 to 2 years):
Silenor (doxepin): This medicine worked beautifully for me; I have no complaints. But when my insurance changed and I couldn't take it any longer, I had to try and go without it. I didn't realize that it had been the source of my weight gain and why I couldn't lose the weight no matter what I tried. After stopping taking it I dropped 10 lbs almost immediately WHILE I WAS ON SPRING BREAK and eating way more than usual and not working out 4 times a week as usual. I'm glad I took it and that it helped me, but I just wanted to share this experience so that others won't mistakenly think that age was causing them to gain weight and not lose it no matter what they tried.
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April 19, 2013 5:12 PM
Learn more about Insomnia
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