User Reviews for Pristiq

Only on day 4 of Pristiq, 50 mg, but definitely feel a difference. Yesterday was the first day I didn't feel like getting through the day was going to kill me. Had a miscarriage 3 1/2 weeks ago, but always had disthymia (clinical depression.) Tried everything you can imagine before. Celexa helped but stopped working a year ago. Also gained weight due to antidepressant. I've lost a pound or so this week since starting Pristiq, and I don't feel so hopeless and sad since yesterday. I am smiling again, laughing again and making jokes. I'm not feeling as happy as I know I can, but I've only been using Pristiq for 4 days. I'm looking forward to continued results. Side effects? If there are any I haven't noticed as I'm still dealing with miscarriage.

I've taken many antidepressant over the past 15 years. Prozac, Celexa, Lexapro, Cymbalta as well as Wellbutrin. I never had any worrisome side effects until Pristiq. With Pristiq, my normal blood pressure increased by 40 points within a couple of days. I went back to using Lexapro and my blood pressure went back to normal.

The first week it wasn't too good but after it was in my system..BRILLIANT! I am happy, in control of my emotions and back studying and being the best mum I can be ...wonderful.

I suffer from anxiety, depression and panic attacks. 9/10 because its working for me but it's only the second anti-depressant I've used. I was prescribed Cymbalta but had terribble nausea, body tremors, hot flashes and panic attacks. With Pristiq I had nausea for three days but it was bearable and I was really restless. I had so much energy I walked around the block 3 times a day or more in the first week. It did stir up my depression and I had suicidal thoughts which is quite controversial because I never want to die and know in myself I would never do that to my girlfriend and my family I had insomnia the on the second night after starting my Pristiq but have had no insomnia ever since. All my side effects were gone after a week and then I was given a prescription for it. Life changing stuff.

I been on and off of meds for quit some time, Prozac being the longest 4 yrs but then it just stoped. On ativan 2mg 4x's a day or how ever i want to take. I just started the pristiq like 3 days ago. The first dose was the worst. throwing up, sick to my stomach really bad..couldnt eat a thing nor drink anything, BP went up, and i just couldnt relax my legs just want to shake *RLS* But today is the 3rd dose and Im not as sick but sill no appitite my vision is some what blurred, didnt sleep very well even with the ativan. But im not as moody and mean as i was 3 days ago. So i guess its working...

I have been on many antidepressants for depression and anxiety. I have suffered with this for years, and I just started Pristiq today. Already I feel like I am more awake and can concentrate better. I am on 50 mg extended release tablets. I hope that it helps me more in the days to come to feel even better. So far it seems to have helped even though I just took it today!

I started Prisiq on 3/22/10. The main side effects were not sleeping well and night sweats. This lasted only about 4 nights. A bit of nausea, not enought that I couldn't handle and that was it. I am now on my 3rd week and I am doing fine. I do feel much better, and have more energy, since before the Pristiq, all I was doing was sleeping. If someone has never taken an antidepressant, the side effects can be alarming. I went cookoo and no sex drive on Zoloft and Cymbalta. Pristiq, whatever is different about this SRNI seems to keep me at an even keel. I will give Pristiq at least 3 months before I give a full report.

I have adult adhd and major depression. I have taken Adderall for the past 4 years and suffered from drop off in the evening. I tried Lexapro, Wellbutrin, and Cymbalta, and Effexor. Pristiq is by far the best and has made a significant improvement in the quality of my life.

I was only on Pristiq for 3 days before I had to stop taking it cold turkey. I've dealt with restless leg syndrome since my childhood (I'm now 20), but it would only affect me once or maybe twice per year. Out of the 3 days of taking Pristiq, I suffered from terrible restless legs while trying to sleep for 2 nights. I think the 2nd day I took it I had already experienced a bit more energy and felt sort of happier and less stressed, but unfortunately I cannot continue to take it due to the negative side effect. By the way, I know it's bad to stop taking anything cold turkey, and I'm currently suffering from that as well because my doctor hasn't returned my calls regarding the issue in 4 days.

Warning, Caution! If you are doing Remicade treatments for Crohn's disease that involve IV Phenergan. The day after my 56th treatment I took my 2nd dose of Pristiq and within 30 minutes almost passed out, became very disoriented, drifted in and out of reality. I have done 56 of these treatments and yes the after effects of Phenergan and Remicade tend to make you tired for a couple of days but not disoriented. I have waited a couple of days to let the premeds from the treatment get out of my system more and will try Pristiq again BRAVELY! I can note that the first dose I took the day before my treatment had no effects like this so it must have had an interaction with something (either the Remicade or Phenergan.

I'm a Veteran and have suffered from PTSD for about 10 years, also Major depressive disorder. I have been on a range of Anti-depressants over the years most of which worked to some degree for a while. I was on Cymbalta for the last 18 months which did the trick but I felt Nothing..like a Zombie with zero sex drive. I weened off it over several weeks then on to Aropax, with the worst anger and depressive feelings I've ever had. I have now been on Pritiq 50mg for about 5 days, and felt the affects after day one, My anger has all but gone and I feel normal, I'm able to function well with no side effects so far. My Dr recommends I increase to 100mg in a few weeks time but if I'm feeling this good I may not have to. Here's hoping.

I suffer from Dysthymic Depression and had been on Prozac until it stopped working and I started having suicidal thoughts. I've been on Pristiq for 3 months and it has changed my life for the better. I take it in the morning so I sleep at night. I am no longer tired. I have tons of energy and have a zest for living again. I have dropped 12 lbs and it does not affect my energy levels for running, biking and weight training. I can focus better at work and my sex drive has returned after being dulled for the past 7 years. My husband is thrilled. This drug has been a positive step for me.

I experienced 3 of the most common side effects of Pristiq. I experience nausea, loss of appetite and dizziness. The nausea and loss of appetite were minimal and I could get along with my day. However, the dizziness, in my opinion is not a side effect to be taken lightly. I was so dizzy, I could not concentrate or do well in class. I had to stop taking it because it was disrupting my school work very badly.

It's probably different for everyone, but the general consensus from what I've read (places like WebMD) and from my physician is that antidepressants take 4-6 weeks to take full effect. I've seen many posts here where folks have taken their medicines for 3 days or 2 weeks and are ready to give up already. Please give your medicines time to work. Most of them become more effective (to a point) over time. Hang in there!

I have been on Pristiq for one month. Previously I was on Wellbutrin XL 150 (buspirion) but I was getting very irritated and angry. As a kindergarten teacher, this was not good. Pristiq has me happy and smiling again with little irritation or anger. The one thing that Pristiq is doing is making me binge eat. With Wellbutrin, I lost 20lbs after 4-5 months. One month on Pristiq and my weight is going back up. My motivation levels are down, I don't want to get up and go to work. I want to ask my doctor to let me try Wellbutrin and Pristiq together. I am hoping that the two together will work to get me motivated, happy and losing weight.

I've only been on this for 5 days, and it is not normal at all! lots of sleeping, extremely dizzy, and feel like vomiting!

I started taking Pristiq about 3 months ago for depression and anxiety. I was prescribed Klonopin as well. Firstly I had few symptoms. I had a little head ache and a tightness in my abdomen. It subsided after a week or so. You have to give Pristiq time - it didn't start working for me for an entire month but when it did I finally knew what normal felt like. No symptoms other then happyness. Sleep is great. Sex is great. Life is great. I cant ask for more. However I did stop taking it for 5 days with the withdrawals of irritability. So I quickly restarted. I hope this works long term for me.

I am a 77 year old male. My Grandfather and my Father suffered from Depression. I have suffered from depression all of my life. I was first diagnosed with severe clinical depression about 1975. I was put on ELAVIL and the results were very good and I took it for about 12 years. At that time the ELAVIL stopped working and my Doctor put me on NORTRIPTYLINE. That seemed to stop the depression and worked for a long time. When it stopped working, my Doctor put me on PAXCIL. Then, a Psychiatrist added WELLBUTRIN XL. Then my PDOC replaced the generic PAXCIL with PRISTIQ. For the first time in 40 years, my depression has gone!

My doctor recently prescribed Pristiq for me when I went to see him for help with my mood swings. After a rather nasty incident at a family dinner, I decided that I needed help. My family has put up with these swings for years, and sometimes I cry when alone. I did not realize that I was suffering long term depression. I am only on day four of taking this medication, and already I can feel a difference. I don't feel as moody or down in the dumps. I hope this effect continues, as my past self was breaking my family up. I do agree with other posts here that it decreases your appetite. I do not feel like eating at all. As for sleeping goes, I have always had a problem in this area due to being a shift worker. I take sleeping tablets.

After about two weeks on Pristiq, I can definitely say it is helping. I had come off of Effexor (which made me gain weight) and was in a bad state with terrible anxiety. Pristiq has made me feel more balanced. It also reduces my appetite which is a plus. Some dry mouth and nausea, which has subsided. I also wake up more in the night but am able to go back to sleep.

I thought this was the best one yet. However, I experienced EXTREME nausea which worsened with an increase from 50mg to 100mg. I am going through a wash out period now and not sure what my physician will start me on now. Besides having the Nausea, I also had Gastrointestinal symptoms of abdominal cramping, diarrhea, and flatulence (gas). The medication was working for me, but the side effects made me miss work, not do my school work and affected my social life. I have been off of it for 5 days now and feeling NO nausea and much much better. Glad that it works for some of you!

Started with Wellbutrin 300mg - I was way to agitated -- went to Cymbalta - loved it except for the lack of ability in the sack. Went to Celexa - worked okay stayed on it for 3 months but never felt anything. So during the 3 months doctor added Wellbutrin - does not help. Celexa made me feel - no sorry it didn't make me feel anything but overall in some ways I kind of liked not feeling but that is not life. So the doctor changed to Pristiq -- WOW I feel alive, energetic, really great. I hope this continues. Oh yea .. no lack in the sack on this one. My real message here is that I hope each of you continues to work with you doctor and find the right medicine.

I have been taking Pristiq for about 5 months now and after an initial positive reaction...it has let me down. After about 2 months my dosage was increase from 50mg to 100mg. All was well for another short time until a massive and quick weight gain began (25lbs). I was constantly tired but a complete insomniac. Neck and jaw tightening were also a constant. My dose was lowered back to 50mg which helped, again for only a short time. I am now on my 4th day off the drug and feel "crashed". Wishing everyone the best.

Started taking Pristiq about 4 months ago. I am also taking 300 mg. of trazodone to go to sleep (horrible insomnia). I also take 5 mg of Xanax a day. I started off at 50 mg on the Pristiq but I wasn't noticing anything different. I still wanted to hide from everyone and not go to work or school. I now take 100mg of Pristiq and maybe it's helping? I am smiling at people, I just hope it is not fake.

I have been taking Pristiq for about 3 weeks now, and I am extremely tired 24/7. Now mind you I do have a busy schedule (full time job and classes 24 hours a wk). I do notice however that things don't bother me like they used to and my crying has eased up a bit. I have started having some nausea, hopefully the tiredness and nausea will diminish the longer I take Pristiq.