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User Reviews for Clozapine

Also known as: Clopine, Clozapine Synthon, Clozaril, Denzapine, FazaClo, Versacloz, Zaponex

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Clozapine.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Paranoid Disorder 2 reviews 2 medications
   
8.5
Schizophrenia 20 reviews 42 medications
   
7.8
Borderline Personality Disorder 2 reviews 6 medications
   
6.0
Summary of Clozapine reviews 24 reviews 7.4

Reviews for Clozapine

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For Schizophrenia: "My son is in his early 20'and has schitsoaffective dissorder.He has been on at least five different medications for his illness. And nothing seem to help or if it did it lasted only for a little while or he had severe allergic reactions. So he started clozapine/clozaril around a month ago. And it has made a big difference .The voices gradually are going away. He can actually sit and watch TV and have a conversation. He is enjoying things again. We do go for blood work every week which he does not mind. This medicine is working and I'm hoping his blood work comes back good every week, Because to see him getting better is such a relief . And I am hopeful for a happy productive life for him. Things are looking up."

   
8.0

Mysonisawsome January 19, 2016

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For Borderline Personality Disorder: "I took this medicine for 6 years as a teenager for "bipolar" (which we found out was a misdiagnosis). This medication made me miserable. I felt like I had died and somehow was still walking the Earth. For the first couple of years I became extremely paranoid, which I had never had a problem with before taking the medicine. The depression was still there. As the dose was gradually decreased, I felt a bit better but still had that feeling of dread. You eat everything. You sleep all the time. You don't care about anything. Coming off of the medicine is almost as bad as being on it! I had severe headaches and nausea, and I lost 10 pounds almost instantly. Clozapine has its place, but you should think hard before taking it."

   
2.0

I Wouldn't (taken for 5 to 10 years) January 14, 2016

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For Paranoid Disorder: "Tried may meds. But clozapine has turned me around. Now working part time. Involved with community and living/loving my life. Medication is not the only key to recovery though. You cant medicate life. II need to be supported and surrounded by people who are good for me."

   
9.0

Rotton fred (taken for 5 to 10 years) October 13, 2015

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For Schizophrenia: "I've been on clozapine for four and a half year for schizoaffective disorder. I was on 350mg but took a seizure and the dose was lowered to 150mg. I feel well mentally but the clozapine has made me very unfit. Also the constipation I suffer has affected my quality of life. I don't feel like socialising any more and have gained 3 stone. Looking into changing to the drug Latuda that is new in the U.K."

   
4.0

CMac603090 (taken for 2 to 5 years) October 8, 2015

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For Paranoid Disorder: "My son has been on Clozaril for 3 years. He was dx with Bipolar when he was just 6 years old. He had literally been on every anti-psychotic drug until his 7th hospItal stay, his regular psychiatrist and the hospital's Dr decided to try this medicine. As far as his psychosis it has been a wonder drug. But physically, Clozaril is destroying his body. In the first 6 months, he was dx with asthma. The worst of his problems that developed in the past 9 months has been GI and liver. He now has severe ensephagitis, gastritis, 4 ulcers and NAFLD (fatty liver disease). He has also gained over 50 lbs. Not just teenage pounds. I was also told when he started the Clozaril, it isn't really approved for patients under 18. Too late now."

   
8.0

Anonymous (taken for 2 to 5 years) September 29, 2015

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For Schizophrenia: "My daughter was prescribed Clozaril as a last resort because I refused to allow her to be admitted to a state hospital. Every other med combination had been tried for 5 years during which she was constantly psychotic, in and out of the hospital. That was nearly 3 years ago and she improves in tiny increments every day. We have learned a great deal during this 8 years: that most psychiatrists don't understand how to treat mental illness because most they don't believe in neurotransmission disorders. They really think "behavioral health" is about poor choices caused by emotional trauma. Clozaril is the only effective med and it is used as a last resort in the USA. The shame is that it is a front line "gold standard" med in Great Britain."

   
10

Anonymous (taken for 2 to 5 years) August 11, 2015

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For : "I am a male aged 48. I was diagnosed with Type I Bipolar Disorder when I was 26. In 2008 it was changed to Schizoaffective Disorder, Bipolar Type. I had been on Depakote from 1994 until 2014. The Depakote caused massive weight gain (I topped out around 240 pounds on it). In April of 2014 the psychiatrists decided to try Clozapine (Clozaril) and discontinued the Depakote. I lost around 70 pounds over 8 months. I now weigh 160 pounds. This is my normal body weight. The Clozapine has been an excellent anti-psychotic and it works very well. Even better than the Depakote. The psychiatrists augmented the Clozaril with Metformin, which studies show can help lead to weight loss. I am as happy as I have ever been on the Clozapine."

   
10

True_Architect August 10, 2015

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For Schizophrenia: "So far this has worked for my grandson. No more voice or the TV talking to him. He still has a little anxiety. It has been life changing"

   
10

lsg July 28, 2015

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For Schizophrenia: "Very drowsy during the daytime. Not sure if my antidepressant needs to be changed, but it is still too early to judge how well Clozaril is working. I'd rather not have to draw my blood every week, because there is a lot I could be doing like going overseas with friends and relatives. By the way, does anyone experience bedwetting in the morning?"

   
9.0

ABC45 July 15, 2015

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For Schizophrenia: "So far it has been the best med for my grandson. He no longer hear voices or is delusional. I am so pleased this is working for him. He is almost back to his old self"

   
10

p moore July 10, 2015

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For Schizophrenia: "I've been on it for 4 weeks, and I don't see a big difference. I used to socialize at coffee shops, but now I feel paranoid, and I want to stay home. There are so many other things that can be wrong since I take several other meds like Depakote ER and Zoloft. I'm going to see my doctor this week, and hopefully find something to help with mood stabilization."

   
7.0

CJK2345 July 7, 2015

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For Schizophrenia: "This medication was absolutely terrible. I couldn't think and everyone had to repeat things all the time. Also I extreme weight gain in barely any time. I always wanted to eat something unhealthy when I walked by somewhere and I had never had that before I was on this medication, at least not as badly as that. In the past I had gradual weight gain but this was rapid. It is also bad for the fact that it gave me seizures twice and I ended up breaking my ankles and they put me on Epival which causes birth defects. Hopefully everything will be better though. I'm on Invega now and it already is better and I don't need clozapine even though the doctors were trying to make me believe it was the only medication that works when it isn't."

   
2.0

Anonymous. (taken for 6 months to 1 year) June 11, 2015

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For Schizophrenia: "I've been on everything to treat my disease, seriously. My condition is a little different. I'm very intelligent, but my positive symptoms kept me in constant fear and stress. I was so unmotivated and depressed I couldn't handle life. My first psychiatrist was terrible. He loaded me up on benzos and SSRIs. It was like dumping gas on the fire. I was so fed up that I switched doctors when I went to college. I've been with him for 3 years now. He did everything he could think of. Some things didn't work, some were incomplete, and some caused horrible side effects. So last ditch he wrote Clozaril. I feel wonderful. I have a $75k job, a car, and a house. Clozaril saved my life."

   
10

Mjm4273 April 13, 2014

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Clozaril (clozapine) for Schizophrenia: "My sister was diagnosed with schizophrenia at about 29 after a third suicide attempt and full blown nervous breakdown. She was eventually placed in a state mental institution for ten years. She only got out due to Clozaril. They tried it on three patients through the national institute of health in Washington, DC. She was released to a halfway house within three months. Although she is still very ill, she remains on this medicine for approximately 23 or more years. "

   
9.0

The Q March 16, 2014

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For Schizophrenia: "One son is schizophrenic and one shizoaffective. After many medicines both have been put on clozapine. Helping a lot with psychotic and social symptoms. Weight gain and lethargy for both."

   
9.0

2boysschizo (taken for 1 to 6 months) July 17, 2013

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Clozaril (clozapine) for Schizophrenia: "I have been taking a small dose 100mg to treat my schizoaffective disorder. I think it helps lower my agitation and helps me to think more clearly. I don't think it helps with my paranoia."

   
8.0

MATT April 29, 2013

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For Borderline Personality Disorder: "My son was had a myriad of diagnosis since he was 3 years old - by the time he was 20 he had been hospitalized numerous times, attempted suicide 4 times, and was uncontrollable. He had been on 19 different medicines over the course of this time with no reprieve. His doctor decided to try Clozaril as a last case alternative - I don't even know what to say, within two weeks his anger diminished, with three his personality started to emerge -the medicine completely changed his life. It was like nothing I had ever seen before. He literally transformed with 6 weeks from a boy who couldn't exist in society, could manage his behaviors or aggression and was completely out of touch with reality into a son I had never seen before. He now works full time. "

   
10

aj2321 February 28, 2013

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For Schizophrenia: "Clozaril has given me my life back. I'm an independent and functional member of society again. I just finished trade school ahead of schedule with no interruptions because of my disorder. I can come out of my shell and make friends again without feeling paranoid. I can walk out in public without feeling that people are watching me and talking about me. I feel that Clozaril is the best antipsychotic available."

   
10

Anonymous (taken for 2 to 5 years) October 26, 2012

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Clozaril (clozapine) for Schizophrenia: "My older brother has had schizoprenia since he was 14 years old in 1970's. He has been on many, many medicines with some or little success. He was then put on Clozaril in his thirty's, what a miracle Clozaril was. He was able to live a almost normal life for over 10 years and within 3 days his life went from happy to hell again, because of his blood test result, we tried to get him back on it but due to the special list with people who have reactions to it are not able to ever take it again. My brother is one of the lucky one's though he has a family that totally supports him and encourages him to live and do the best that he can. He lives in a adult facility that takes care of his needs and makes sure he gets his medicines."

   
9.0

candyb69 September 25, 2012

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For Schizophrenia: "Clozapine has been the only medicine that has helped me with my psychosis. I rapidly deteriorated while in hospital to a point where I had to be on 24 hour watch. 4 weeks after starting it I was released and began studying again. As my psychiatrist said 'it is the golden egg of psychiatric medication"."

   
10

Anonymous November 14, 2011

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Clozaril (clozapine) for Schizophrenia: "My brother's schizophrenia manifested itself in 1971 or 2 when he was around 17. Spent maybe 25 years in state hospital and was on everything and every combination of medicine over the years. The doctors were baffled. He was one of the first to try Clozaril when it first came out in 1980-something. Unfortunately, he was one of the few who had a severe reaction which nearly cost him his life. So sad...BUT I am very happy to read how others have found Clozaril to be such a 'miracle' for them! The trauma and grief of schizophrenia leaves years of devastation in it's wake. I am still hopeful that one day he will have his 'miracle breakthrough' just as others have!"

Century21cyn November 6, 2011

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Clozaril (clozapine) for Schizophrenia: "My friend has been on Clozaril (Clozapine) for nearly 18 years. He went more than 10 years without having a single psychotic breakdown, which only occurred when he lowered the dosage himself. Even though the medicine makes him feel fatigued he has been able to hold down a 40hr/wk job. Nothing short of a God-given miracle!"

   
10

Anonymous July 26, 2011

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Clozaril (clozapine) for Schizophrenia: "My youngest brother has suffered with Schizophrenia for around twenty years & we have also tried him on many meds - some good, some not so good. The main problem is the anguish etc. he undergoes each time he has to be "weaned" off one med & put on another. This is because after a while they all lose their effect & periodically need changing - not so with Clozaril. After being on it for five years, he is still stable, although a recent lessening of his regular dose is causing some anxiety. We hope to have the dosage resumed as previous, but see no need at this time to change him from this excellent medication."

   
9.0

Older Brother January 9, 2011

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Clozaril (clozapine) for Schizophrenia: "Fabulous medicine for schizophrenia"

   
10

Anonymous September 14, 2009

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Clozaril (clozapine) for Schizophrenia: "This medicine works. We had exhausted every other psych medicine on the market over a period of 6 years. My daughter is functioning again. The paranoid symptoms have disappeared. It is worth the monthly lab work. She's been on for 5 years, and no side effects. I don't think our daughter would be alive if not for this medicine."

   
10

Anonymous May 6, 2009

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