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Reviews for Anafranil to treat Obsessive Compulsive Disorder
Review by hapi:
I have suffered from obsessive thoughts for 26 years. I have tried different medications over the years. I was on Paxil for 10 years but I never ever felt totally well and I slowly stopped taking it and became very ill. I started taking clomipramine again seven years ago. Again it saved my life and I have been able to have a successful career. I take 250 mg a day. I hate the side effect of weight gain but I will never sacrifice my mental health to lose weight.
Review by MelissaDutfield (taken for 1 to 6 months):
I started taking this medication 2 months ago, starting on 25mg but was too high as the side effects were bad for me so I started on 10mg slowly to 20mg and I think it has made a big difference. I am doing CBT too but the anxiety has decreased significantly. I suffer from intrusive thoughts and this helps it become more manageable and I feel that I'm living again!
Anafranil has always worked superbly for my obsessive compulsive disorder and I have used this medicine intermittently for 30 years. My mistake has always been to completely stop when I feel well - it always comes back.
Although an amazing medicine, the downside is that it takes about 8 weeks for the medicine to work and before that I usually feel worse. And the side effects can be a challenge.
It has worked really well for my severe OCD, depression, anxiety and panic. It stabalizes my mood too. The side effects are awful for me, though. Sexual side effects (like my genitals are numb) and severe constipation are the two side effects that keep me from being on a more therapeutic dose. At 100mg, the side effects are bad. At 50mg I'm OK in terms of side effects, but the benefits are minimal. I will be going up to 75mg and see how that goes.
In the past I had been on 150mg and then 200mg. I had never been happier. I think I may have been too happy rather than normal happy, though.
18 users found this comment helpful.
I have used Anafranil on and off for 30 years. Each time it has worked superbly. I stop and then start again about 2 years later, for a period of about 4-6 months. Presently taking 200 mg along with Beta Blockers - the best experience ever: I am happier, more confident and less anxious than ever in my life. Anafranil side effects are sometimes bad: loss of appetite, sexual dysfunction and blurred vision tend to him me badly. Also can take 2-3 months before they really work. But worth the wait, even though it feels for a while as though it makes you feel worse. Outstanding medicine - a life saver!!
54 users found this comment helpful.
Anafranil : Most likely the best medicine for obsessive compulsive disorder, overall. Yet each person has their own body chemistry/energy issues.
Most people with OCD need about 100 to 200 mg at night. The key is to GRADUALLY go up in dose. This will give your body TIME to ADJUST to Anafranil. I am now up to 150mg, after 3 months and I am feeling much better. Much less OCD thoughts. Yes, sexual side effects...as with any OCD medicine. I used to take high dose Paxil for 8 years and it just wore out, OCD came back.
I think I will try Anafranil 200 or 225 mgs, stay on it for a year, then see how I do as I try to wean down the dose to 50 or so.
41 users found this comment helpful.
This drug was a MIRACLE for me! My problem was that I was always LATE for any and every little thing I attempted to do and it was ruining my life. It is VERY baffling for me because I started with only 25 mg and within FOUR days I was AUTOMATICALLY, not just on time, but EARLY for everything, without any thought or effort! I was ecstatic. This phase lasted 3 weeks. The doc said I'd be a Super Woman when she amped me up to 50 mg. Well, that made it STOP working! I began to slowly regress, and then started to be extremely drowsy to the point of even falling asleep at the wheel -- and worse, it wasn't even working! We experimented with it but it NEVER worked again and I am super sad about that.
26 users found this comment helpful.
This has been a miracle for me. I suffer from extreme OCD that had left me at times in a state of paralysis and constant fear. This medicine gave me back my life. It will not get rid of all of the OCD for you, but it will make it 90 percent manageable. The Dr who gave it to me was old school. None of the SSRIs worked for me. They were like sugar tablets. This one does. Highly recommend you speak to your physician about it as an option.
51 users found this comment helpful.
I have/had severe OCD. I have been on citalopram, Zoloft and Prozac. I was started on 150mg Anafranil and within what seemed no time at all my OCD disappeared. Prozac did work for OCD but not on clinical depression. I am now on 200mg. I have had no weight gain (nor did I have on SSRIs). I get a dry mouth sometimes but counteract this with a anti dry mouth toothpaste.
23 users found this comment helpful.
After three years on different anti psychotics, I started taking this finally to some releif. I have been taking it now for about six months. It is still working well for obsessing, but the side effects are starting to add up. I have steadily gained weight. Severe dry mouth at first, not so bad now though. Total anorgasmia fixed by Viagra, and uncontrolled twitching. It sounds bad when I write it down but compared to the antipsychotics it's much better. I still feel better than I have and so much happier.
30 users found this comment helpful.
After trying a few different medicines (with no benefits) my doctor pulled out the big guns and gave me Clomipramine. I have severe OCD but the purely obsessional (intrusive thoughts). I used to be a checker and handwasher though.
I took it for over 1 year, Unfortunately Clomipromine did nothing for me on 250 mg, which is pretty much the highest dose you can take. I did not have alot of side effects except dry mouth when I was on it.
I quit taking it after I ran out on a holiday weekend and saw the withdrawal symptoms, severe nausea. And even when tapering slowly off it over the course of months I still had terrible withdrawals (vomiting and nausea).
15 users found this comment helpful.
My obsessive compulsive disorder has improved significantly. It has also helped with depression but I just up my doses from 150mg to 225mg to see if I can get more of an antidepressant effect. Almost no side effect. I take it in the morning and I do not feel sleepy. Anger and irritability has improved as well significantly.
For those who share in the future let me know how much you take please. It helps.
32 users found this comment helpful.
I've been using Anafranil for 6 years. It has helped me a lot. On occasion I still struggle with obsessive thoughts but have been able to bring it under control both times by myself. I rated this an 8 because of dry mouth and constipation problems. Eat your fiber big time. After several years, the dry mouth problem got better and only returns when I'm under stress. I sleep well on this drug and did not sleep as well on the SSRIs.
36 users found this comment helpful.
Works well for OCD, wonderful for body pain, and moderate for depression (it takes 6-8 weeks for me to see any effect) but the side effects are not pleasant - dry mouth, fatigue, drowsiness, difficulty concentrating and anorgasmia.
38 users found this comment helpful.
Anafranil saved my life. The side effects are not pleasant, but not having the intrusive thoughts is well worth the effort! I am scared of long term effects, but my fears are lessened by the effectiveness of Anafranil for OCD.
34 users found this comment helpful.
Ever since I was ten years old I have had obtrusive images of inflicting pain/suffering on myself and others. These images create emotional turmoil in life, because obviously I don't want these thoughts. I've tried different medications, yet Anafranil seemed to work the best. My obtrusive thoughts went away almost completely (granted I was on the highest dose). However, Anafranil had consequences: It gave me irregular heartbeats, and heart palpitations to the point where I felt like I was having a heart attack. I had to wean off the medication because of this. This was distressing to me because Anafranil made me emotionally feel like a million bucks, but physically made me feel dumpy.
36 users found this comment helpful.
My son is 14 and has suffered with OCD for 2 years. Lexapro made him a happier obsessive with extreme gas but OCD symptoms no better. Anafranil has been great. Has fewer obsessions with less anxiety. It's an older drug you have to ask for.
40 users found this comment helpful.
After taking this medicine, I woke up one morning to realize that I felt connected to the world and when I started to do my rituals, I realized that I just didn't need to. Amazing. The problem was that I gained 40 pounds, and the high dosage necessary (over 200) scared me. I would recommend that a person try it and see if a lower dosage will work for them. If so, it's a miracle.
45 users found this comment helpful.
From reading the medical literature this is probably the most efective treatment for obsessive compulsive disorder but the side effects led me to change, after a year of use, to a less taxing medication. The weight gain was too much and it made me more confrontational with others. But for bringing my initial problem down to a manageable level before switching, Anafrinil was a life saver.
39 users found this comment helpful.
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