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Wellbutrin SR User Reviews & Ratings (Page 2)

Wellbutrin SR has an average rating of 7.1 out of 10 from a total of 129 reviews on Drugs.com. 62% of reviewers reported a positive experience, while 18% reported a negative experience.

Reviews for Wellbutrin SR

  • rillmad
  • July 27, 2016

For Depression "I'm not usually one to publicly review medications, but I really feel the need to with this one. I have been clinically depressed for about 6 years. I have tried Celexa, Lexapro, Zoloft, Prozac, and Effexor. Trial and error is really a bummer when you want to get well and you have little to no relief. I am now on a mix of 300 mg of Wellbutrin SR and 100 mg of Zoloft and love it! The first week or two I experienced some nausea (the traditional side effect) that had me down for the count for a few days, but I stuck with it. My only complaint after about 4 months of use is the insomnia, but that's nothing melatonin can't fix. So, if you've tried every SSRI/SNRI under the sun, I totally recommend trying Wellbutrin."

8 / 10
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  • Zaps
  • Taken for 1 to 6 months
  • March 31, 2013

For Depression "I just was put back onto Wellbutrin after attempting 3 other antidepressants. It was only after being off it that I realized how good it worked for me. I was taken off of it because it caused me to have some issues with irritability and according to my family- short tempered. I was put on Cymbalta, but I enjoy a drink or 2 a day with my wife (Cymbalta and alcohol will destroy your liver- very well documented). Zoloft made me feel completely despondent, and I felt life was no longer worth living, not to mention made me not even remotely think of sex. When I was put back on Wellbutrin, I felt like life WAS worth living, and I feel happier and euphoric. Now I take Lamictal with Wellbutrin 150 mg in the morning. Avoid the XR- causes insomnia."

8 / 10
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  • Joker...
  • September 3, 2017

For Depression "Dopamine and norepinephrine are two major brain chemicals in the feelings of romantic love. Serotonin (key in SSRIs) actually suppresses dopamine and inhibits feelings. This dopamine and norepinephrine (a stimulant) reuptake inhibitor can help and and DRIVE without sexual side effects, weight gain, and apathy caused by SSRIs. Often prescribed with an SSRI to counteract side effects of it. Also it is reported to have few side effects (unless you suffer from a seizure disorder that is). I recommend this over an SSRI or in addition to one."

9 / 10
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Frequently asked questions

  • isa
  • Taken for 6 months to 1 year
  • April 24, 2020

For Depression "I've been taking Wellbutrin 150mg SR (generic) once a day for the past 6 months. I have had no negative side effects. It was originally prescribed to treat my Binge Eating disorder but it did nothing for it. BUT it did improve my depressed moods drastically! No needing check lists anymore to prompt me to do all the basic stuff a normal human being should be doing, like take a shower.. So for about 5 months I was not depressed anymore, I was also less anxious and had less intrusive thoughts. I now think, one month later (so after 6 months), that I should bump it to twice a day (like it's intended in the first place anyways) because my depression and intrusive thoughts are slowing coming back and ruining my attempts at self-care. In the past I took Paxil and Effexor. Paxil never worked. Effexor worked for a while (with bad side effects), then stopped working for me. I hope I have now found what will work for me long term!"

10 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • October 19, 2016

For Depression "I just wanted to say that I had a lot of these negative symptoms when I was in the generic "Buproprion" (headaches, vivid nightmares) but after switching to the "name brand only" I no longer had those horrible side effects.. It's hard to tell in these reviews which people are taking the generic version ( which was horrific) and who is reviewing the actual Wellbutin SR. The name brand worked so much better!!!"

9 / 10
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Are you taking this medicine?

  • Kayyy...
  • January 8, 2018

For Depression "I started taking 100mg XL in October for my depression. For the first 3 weeks I kind have just felt the same. Then I was moved up to 200mg SR and that’s when I started noticing a change about 4 weeks in. It reduced a lot of my depression along with my 10/10 anxiety. After 3 weeks, I started 300 mg SR and I definitely noticed a change. I had a lot more energy, starting doing things I once enjoyed, and did better in my college classes. With weight loss, I lost 16 pounds after the first 2 weeks of taking the 300mg SR. Overall, wellbutrin has worked so well for me and has helped reduced my depression and anxiety. 10/10"

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  • Lori
  • November 5, 2015

For Major Depressive Disorder "I was taking 300mg every day the generic for years along with zanex for anxiety. My dr upped the dosage to 450mg every day. I just got the name brand and it's completely different!!!! My life has new meaning the generic is not half as good. I no longer need the zanex and have no problems going out or living my life now. This medication ( name brand Welbutrin) should be available to anyone that needs it. The generic is horrible loaded with side effects shaking, headache, nausea, and extream bouts of anxiety that do not occur with the name brand!!! I am shocked the generic for this medication is permitted to mascrade as the equivalent is not even close!!!"

10 / 10
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More FAQ

  • Linds
  • Taken for 1 to 6 months
  • June 9, 2019

For Major Depressive Disorder "Once I started taking Wellbutrin, it was wild. I forgot what it was like to feel anger and lust. I forgot what it was like to not feel exhausted for no real reason. Even small things like listening to music became wonderful again. I was very manic when I first started taking the medication. I could feel myself being reckless and putting myself in dangerous situations. I'm also more aggressive on Wellbutrin, but it's just something I have to be aware of and learn to control. I stopped taking my anti-anxiety meds after taking Wellbutrin, too, because they made me wildly dizzy when I took them with Wellbutrin. Additionally, I can be anxious/have irrational thoughts now, but it's nothing from which I can't talk myself down. Overall, my self-esteem and sense of wellbeing has vastly improved. I'd highly recommend Wellbutrin to anyone whose family has a history of mental illness. I think the boost of dopamine and norepinephrine really helps with MDD."

8 / 10
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  • Cool...
  • Taken for 1 to 6 months
  • December 23, 2016

For Depression "Seeing that most anti depressants take time to actually build up in your system before sustained relief occurs, I have begun taking it and thankfully have felt a decrease with many adverse symptoms of my depression. Sex drive and focus has slowly begun to amp up and I feel more at ease consistantly. I personally have had a good experience on this med. Good luck on your quests for sustained relief."

9 / 10
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  • John...
  • Taken for 2 to 5 years
  • August 14, 2013

For Depression "I had tried four of five different SSRI's over 10 years and they didn't work for me. Also, I was put on Serozone some years ago by my GP and that medication just wasn't for me - it was finally taken off the market due to it's horrible side effects. Finally, my doctor prescribed Wellbutrin SR and it worked wonders for me. I had only one side effect which was waking up at night. I'll take that over depression any day."

9 / 10
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  • macyy...
  • October 3, 2016

For Depression "it's pretty damn great! it makes me feel so much better. although it causes significant weight loss. i was 5'3 100 pounds (on the verge but fine considering my frame) but now i'm 89lbs. so yeah that's not good. if you're tiny like me naturally, i wouldn't recommend...but i tried every drug on the planet and the side effects are worth it. i just have to force myself to eat more"

9 / 10
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  • Happi...
  • September 2, 2010

For Panic Disorder "I started taking Wellbutrin SR about 2 weeks ago and I am already noticing a difference. I had a lot of anger, frustration, stress, and small panic attacks with uncontrollable crying. Now since I have been taking it, I am much calmer and I am able to determine what is worth worrying about and what is not. I could not do that before. The crying has stopped and I no longer feel stressed or angry. The only side effect I have is a mild headache, a little insomnia, and extreme thirst. Those I can deal with versus what I was dealing with. I am definitely going to keep taking it."

9 / 10
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  • LCano
  • Taken for 1 to 6 months
  • August 27, 2019

For Depression "I had every bad side effect and it crept up over time. Insane migraine headaches, stomach pain nausea, ear pain, ringing in the ears, vision problems, vertigo, suicidal thoughts. I also had very frequent urination. The agitation and angry outbursts were really frightening. I was completely fine for 3 months so I didn’t make the connection between the drug and the symptoms at all. I went to doctors for headaches and my bladder and even for allergies until I figured it out myself. I finally thought to myself, what did I start doing differently in my life? It was the Wellbutrin. I called my psychiatrist and told him my symptoms and he told me to stop taking it immediately. I’m glad I figured it out. I really don’t think anybody else other than myself would have. It has been a really rough few weeks with this pain. I felt almost immediately better when I stopped the medication."

1 / 10
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  • Cloud
  • August 13, 2015

For Major Depressive Disorder "Struggled with MDD and Gen. Anxiety Dis. And self harming habits. Wellbutrin has changed my life. It's definitely a noticeable chemical adjustment for the first few weeks. Once I adjusted though, it was a miracle. I'm calm, don't have anger or outbursts, no anxiety, NO obsessive thoughts or ruminating. I haven't been depressed in over 3 months and I started Wellbutrin in Feb. of 2015. I've had no side effects besides the first few weeks. You will feel very weird for two weeks. Stick with it. No weight fluctuations, dry mouth went away, no sexual side effects and I have more energy but I don't feel artificially stimulated (you will for about a month though) I give this medicine a 10. My doctor says I'm textbook MDD. Runs heavy in my family"

10 / 10
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  • Mauifun
  • September 16, 2011

For Depression "I like Wellbutrin SR. It helps me lose weight I was at 174 and now at 155 where I should be. I have tried over 11 medications, but this seems to work great. It gives me more energy which I need working 2 jobs."

8 / 10
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  • becky...
  • October 24, 2009

For Depression "I have tried several other medicines and all they did was a large weight gain, about 45 lbs. So I suggested to my doctor about Wellbrutrin SR and I have since lost the weight and have kept it off. So I'am now a happy and thinner woman."

10 / 10
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  • Anonymous
  • June 14, 2008

For Depression "I have tried all sorts of antidepressants but Wellbutrin SR has been the only one that actually gave me energy instead of making me want to take a nap every afternoon. One of the nice side effects of Wellbutrin is it helped me lose weight."

10 / 10
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  • Big...
  • September 15, 2011

For Depression "2 and 1/2 months on WB. Quality of life improved significantly. I am more emotionally resilient, have an increase in daily energy and I feel more motivated to do the things that were languishing on the back burner before. I have been on other ADs and this one is different; it didn't numb me, it lifted me up. The range of emotions is still there. But the difference is I can come back from sadness without being a total mess. It hasn't made me a better person, it's just made life less of an uphill battle. I've lost 20 of the 30 lbs I needed to lose so far too. Cons: lengthy start up phase (7 weeks for me) requires lots of patience, plus I couldn't sleep properly on Wellbutrin without my trazodone at night."

9 / 10
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  • Anonymous
  • June 8, 2008

For Depression "I started taking Wellbutrin six years ago. I'm still taking it. It just works, I don't really know how to explain the way I feel except much calmer, less agitated, less sad. I thought I didn't need it any longer because I felt so good for many years and tried going off of it but after about 3-4 weeks, I felt just as I had prior to ever taking it. So, I never have any plans of going off it."

8 / 10
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  • Astig
  • Taken for less than 1 month
  • December 14, 2017

For Depression "I just started taking a very small dose of Wellbutrin and will be gradually increasing. It is being prescribed for major depression and anxiety. For the past 2 years when I wake up in the morning it's usually quickly followed by a terrible anxiety that usually goes away but can take a few hours to do so. Anyone else experience this morning anxiety?"

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  • Srw
  • Taken for 2 to 5 years
  • October 14, 2015

For Major Depressive Disorder "A noticeable difference between the brand and generic (buproprion). Started out with brand years ago. I was no longer stuck in bed avoiding life. I could concentrate, no impulsive decision-making or stuck with indecision. Interested in life again, getting out, and lost 40lbs w/in the first year. Then insurance changes meant getting generic. I thought, "no big deal, I take generic for everything". I soon found myself overpowered by MDD symptoms again while still taking an AD. Dr mentioned switching to generic was likely the problem. I've since found lots of FDA/med research/similar experiences. Thankfully, I'm back on brand doing good, it wasn't just all in my head. There really is a BIG difference."

9 / 10
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  • Sadbe...
  • December 10, 2015

For Depression "I started taking it about 3 weeks ago at the 150mg dose for depression. First week I felt very little change but that was actually a plus as many antidepressants I have tried have made me feel physically terrible and mentally kind of.. Sketchy? But with wellbutrin I only had minor headaches when smoking (not surprising considered its original use was as a cessation aid) and some very vivid dreams. At this point I am really starting to feel a change; random weeping down to once this past week rather than every damn day; starting to feel hopeful about the future again, showing more interest in my past hobbies, feeling grateful. Only downside is it has really increased my acne, so I had to step up my skincare game."

8 / 10
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  • depre...
  • Taken for 1 to 2 years
  • May 9, 2015

For Major Depressive Disorder "I got to a point where I was in bed 20 hrs a day, couldn't work etc. Severely depressed .I've battled that all my life but never got on an anti depressant . Wellbutrin along with lexapro 20 MG changed my life. Mainly the wellbutrin as I truly changed when that was added. I'm on 300mg SR. AT first you'll feel jumpy and anxious but give it 3-4 days, week tops, and it'll be incredible I have a new job, I'm traveling. New person."

10 / 10
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  • Anonymous
  • February 17, 2012

For Depression "I'm on my 3rd week of bupropion and I have finally started seeing a difference in myself. It was a Thursday and I was in clinicals, I'm in college for athletic training, and I was just my normal friendly happy energetic self. Out of the three weeks I have had dizziness once and I have noticed some trembling but so far so good and I really feel like I'm getting back to my normal self. I had been down for so long I'm just glad I finally did something about it!"

9 / 10
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  • DW27
  • Taken for 1 to 6 months
  • September 26, 2012

For Depression "I am on bupropion SR for 2.5 months and it's been pretty good so far. I don't sleep all the time like on citalopram and my weight stayed the same with a slightly diminished appetite. The depression is mostly gone even though I'm unemployed for a long time living off dwindling savings. But I'm actually trying to get work now since I have more energy and feel generally better than ever despite the economy. My libido isn't much despite other comments here. Some anxiety still there and a few drinks in the evening help that. The biggest side effect is extreme sweating when it is humid and above 70 degrees. It's embarrassing. For me, bupropion (Wellbutrin SR) 100mg twice a day mostly works. Good luck."

8 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.