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Budeprion XL User Reviews & Ratings

Budeprion XL has an average rating of 7.2 out of 10 from a total of 31 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 13% reported a negative experience.

Reviews for Budeprion XL

  • Jesslyn
  • Taken for 1 to 6 months
  • April 22, 2023

For Weight Loss (Obesity/Overweight) "I have been taking Budeprion XL 150mg once a day for the past 3 months for depression, and I have to say it is the "happy pill." My depression has gotten better, I have more energy, sleep better at night, and my anxiety has decreased. Additionally, I have noticed that my appetite is suppressed, and I have lost 20 lbs in 3 months. I have also cut back on smoking cigarettes. I honestly have never felt better. Before taking Bupropion, I had taken Sertraline, which only made me feel more depressed and caused me to gain weight, which made me feel worse about myself. Bupropion has been a win-win for me because, after having a hysterectomy, I lost my sex drive, and Bupropion has given it back. The only side effect I have experienced from the medication is dry mouth, but I can deal with it. It actually makes me drink more water, which is something I never used to do in the past."

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  • Rachel
  • Taken for 5 to 10 years
  • November 28, 2019

For Depression "I've been on Bupropion XL for almost 7 years after trying every other antidepressant and suffering all their side effects. They made me sleepy, weird, and generally vapid. If I'm honest, Bupropion did and continues to do nothing for my depression. I think it might even have made my anxiety worse. BUT--and this is a HUGE but--I feel like myself. I'm awake, I'm alert, and I. GET. STUFF DONE. Seriously, I started Bupropion and wrote a 140k word novel that month for no reason whatsoever. Regular antidepressants took away my depression, but they also took away everything else, and that just made me more depressed in a different way I couldn't quite feel. Bupropion gave me myself back, it kicked me in the ass and slapped me across the face and forced me to do the things I want to do. I'm still depressed, but Bupropion showed me how to live with it."

10 / 10
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63 Report
  • Anonymous
  • Taken for 1 to 6 months
  • November 14, 2012

For Seasonal Affective Disorder "I was originally prescribed this for seasonal affective disorder. I took this for about two years. I then went off. I have notice that seasonal issues slowly begin to reappear. I also noticed that my self diagnosed ADD issues were really beginning to get the best of me, especially the thoughts running wild when I should be sleeping. I noticed an immediate change but going back onto Bupropion XL 150 mg. This has helped to keep me focused and has given me a regular sleep ability again even though I am a 2nd shifter. I am glad to have my life back."

8 / 10
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Frequently asked questions

  • rln
  • Taken for 1 to 6 months
  • May 12, 2023

For Depression "I was on Wellbutrin XL 150mg for 16 weeks. I was experiencing dizziness, hair loss, migraines, constipation, and fatigue. I saw my psychiatrist and she suggested I try the name brand and gave me 4 weeks of samples to try. Immediately my side effects went away. I felt so much better. Unfortunately, my insurance would not approve the PA for the name-brand Wellbutrin. I ended up switching to Aplenzin which is similar to Wellbutrin it just came out. It is working well. So point ifs if you are experiencing side effects don’t get off the medication try a name brand. Hopefully, your insurance will pay for the name-brand. The funny thing is my insurance would pay for name-brand Wellbutrin. They are paying for Aplenzin which cost more than the name brand."

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  • Momma...
  • November 26, 2015

For Major Depressive Disorder "I am a 53 year old woman, I have struggled with depression probably since my 20"s. I would go to my family Dr and she would prescribe an antidepressant, it wouldn't work and I would be given another one to try. This went on for many years. Until 3 days before Christmas last year , I had a major breakdown and my husband took me to hospital crises unit, there I met my psychiatrist!!! Thank God!!! After talking with him he prescribed Bupropion XL 150 mg once a day. I have been taking it now for approx 1 month. It didn't seem to be doing much for me (or so I thought ) until this week, It just seemed like a heavy fog has been lifted !!! I'm hoping each day will get better and better."

10 / 10
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Are you taking this medicine?

  • glosta
  • Taken for 6 months to 1 year
  • October 28, 2020

For Depression "I'd been on Budeprion 150 XL for close to 1 year; felt 'ok' yet hoped to feel better. I knew something was off so the doc suggested upping to 300 XL. Felt improvement but soon developed tremor so we decided to try alternating days, ( ie: 300 XL Monday, 150 XL Tuesday, etc ) which eliminated the tremor and also improved my mental state. Another side effect of 300XL was an increase in libido, sounds good, but almost too much. It decreased after a couple of weeks. How do I know the mix is working? My thoughts are in a steady state of the present, no longer projecting into the past or into the speculation about the future. I'm not one for wishful thinking but I do hope the Wellbutrin continues to work for my mental health."

9 / 10
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  • Unico...
  • October 14, 2016

For Major Depressive Disorder "I have had depression as long as I can remember,I went to my Dr and he prescribed me Prozac, I honestly vaugly even remember anything about that, which was one of the symptoms forgetfulness it was REALLY bad so I got off of it and got prescribed lexapro all that did was make me sleep 24/7 so again I got off of that and finally was prescribed Bupropion 150mg the symptoms in the beginning weren't to bad and within about two weeks I began feeling like a human being again. It literally felt like a huge weight had been lifted off me. :) The only symptom I seem to have that's really bothersome is it gives me really bad insomnia, other then that it's great. I'm proud to say I've been on it almost a year now & it's definitely improved my life. :)"

9 / 10
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  • Anonymous
  • November 16, 2008

For Depression "I recently switched from Wellbutrin XL to the generic form Budeprion XL to save money. After several weeks I realized the medication wasn't working like Wellbutrin XL. I'm all for generics usually, but in this case, the generic drug doesn't work."

1 / 10
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  • Anonymous
  • February 5, 2010

For ADHD "I have been taking Wellbutrin for 8 plus years. Then went to SR, then XL. Helped with my ADHD with Adderall too. Went off for about a year and started back. To save money went to generic 150mg XL - they were great. When Dr. suggested increasing back to 300mg daily (as previously) I agreed. I started taking the 300mg XL generics - the symptoms returned. I noticed when I opened the bottle there as a noxious odor given off. After 4 weeks couldn't stand the smell and returned the rest of the pills to my pharmacy. They replaced them and said they would look into the problem. The 150 mg SR generics stink too. Only the 150mg XL generics don't."

2 / 10
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  • brugb...
  • March 7, 2009

For Bipolar Disorder "When this generic was added to my large list of drugs (including one other anti depressant) I became the most mellow person in the world. Nothing upsets me. Everything moves along nicely. Feel a little disassociated with the world actually. BUT I QUIT SMOKING! So now I won't let them take it away."

10 / 10
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  • Anonymous
  • April 18, 2010

For Depression "I have been taking this generic for several years. It worked great. Now my pharmacy uses a different manufacturer every time I refill. What a difference. With the Watson brand I'd rate this a 10. I'm currently on the Activis brand and I would rate this a 0. All symptoms back. I found a few of the other brand and took them and felt great but now I'm back to this most recent refill and it's awful. All I can say is although there is supposedly the same ingredients not all generics are equal."

6 / 10
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  • Madeit
  • Taken for 2 to 5 years
  • June 13, 2021

For Major Depressive Disorder "This has been the only antidepressant that works for me. I have suffered most of my life from anxiety and depression. Before taking this, I was obsessed with time, would ruminate constantly, pending sense of doom, no motivation, and just tired. I used to be addicted to Adderall, meth, and once I stopped I became a compulsive snacker. This medicine helped me lose 50+ by helping me get up to exercise, not overeat or obsess over food. It helps me be my best self, and I no longer wake up dreading the day. I take 450mg. 150mg + 300mg"

10 / 10
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  • honey...
  • Taken for 1 to 6 months
  • July 29, 2013

For Depression "I've been suffering from depression and anxiety for 8 years with little relief from other antidepressants and combinations (Zoloft, Lexapro, Lexapro & Lithium, Imipramine, Desipramine) and cognitive therapy. I became so sick of switching medications that I just pretended everything was okay until it was too much to bear. I've been on Budeprion XL for about a month now, increased from 150mg to 300mg. Other than a periodic rapid heart beat, some brief sleeping interruptions, and a tad bit of irritability, I can honestly say I'm starting to feel a bit better. I've got more energy than I've had in a long time as well. I would just recommend that if you're a heavy caffeine consumer, maybe cut back a bit to reduce some of the symptoms."

9 / 10
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  • Pats
  • March 26, 2015

For Depression "Have taken other medications in the past and stopped due to the side effects. Now I take bupropion xl 300 mg a day with no apparent side effects. I can laugh. I can still cry. I don't dwell on bad things. It makes me just feel better. But Dr accidently wrote for SR once. I went ahead and took a dose (thinking it would be basically the same, only a little faster acting - I took a 150 mg dose) and was sick as a dog and felt drugged. Amazing the difference in XL and SR - and I imagine the fast acting would be even more severe. I'll stick to the XL."

10 / 10
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  • Anonymous
  • August 18, 2009

For Depression "What can I say this is a GREAT medicine! It was prescribed to me to prevent migraines and depression and it work wonders. I stopped getting migraines from 2-3 a week to maybe 1 a month, helped me improve my energy, sex drive and YES I lost about 25lbs in less then 3months LOVE IT. I would so recommended it to anyone."

9 / 10
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  • Anonymous
  • November 19, 2011

For Depression "I have been using Budeprion for about 3 months and not only have I quit smoking, it has helped me in other ways mentally. I would not say that it makes me "happy" but it has given me such moments of clarity/enlightenment."

9 / 10
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  • mrdoo...
  • June 17, 2009

For Depression "I have been on bupropion for mild depression for many, many years. I switched to the 300XL recently, in order to only take it once a day. I had tried many other anti-depressants and found one overriding side effect - sexual problems. With the Budeprion XL, I have no such effects and the drug works very well."

9 / 10
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  • Thrifty...
  • Taken for 1 to 6 months
  • April 16, 2018

For Major Depressive Disorder "My experience will taking it it was a lifesaver in really help me like I used to really feel down in the dumps and it's really helped me come to be my real self I used to hide behind being fake and just letting people walk on me and putting me in a deeper depression this saved my life"

10 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • January 1, 2020

For Depression "So I've been taking Wellbutrin XL150 for a month and then increased my mg to 300 daily currently. It helps with a lot of issues I have with mood swings and severe depression. Just like the anon below me I now have premature ejaculation which is something I've never had before, literally went from having 10 minutes of sex to 30 seconds and it's making me feel less confident."

7 / 10
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  • Dee
  • October 20, 2016

For Major Depressive Disorder "I have been on bupropion xl 300 for 5 days. The first day I had great energy level but felt wierd. Day 2-4 I have had bad anxiety, no appetite and not sleeping good. Day 5 today seems to be a better day. I still have energy which is good and anxiety seems to be diminishing. And if I loose a few pds I wont be sad. Im sure it will take weeks to get to where I need to be, hoping for the best and just trying to ride it out. Any advice?"

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  • sadly...
  • Taken for less than 1 month
  • March 24, 2016

For Major Depressive Disorder "I started off with 150 mgs then went up to 300mgs after 4 days. Within the first 4 days I started having mood swings. I'd be angry one minute, cry the next, and then I'd be fine. After two weeks, the mood swings decreased a bit, but I started to space out, and began to experience some significant short term memory loss. I had no recollection of conversations that I had just completed minutes before, couldn't recall where I put something I had in my hand just a few minutes prior, etc. When my family started to voice concerns about my odd behavior, I stopped taking it. I was on it for about 3 weeks. Scary. "

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  • ncshe...
  • June 4, 2009

"I have been taking Budeprion XL for 1 month now. It has changed my life. I am smoking less, have more energy and my sex drive is off the chart. I have never felt this great before in my life. It is a wonderful drug."

9 / 10
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  • dudeman
  • January 10, 2010

For Depression "Wasn't on this drug for very long, only about 2 months. I felt mildly stimulated, but got no great effects from it. No side effects either however. The reason for the high rating is that it destroys all pleasure of smoking for me, to the point that I don't want to smoke due to the fact I won't feel it. Also the only popular antidepressant I know that doesn't affect sex drive in a negative way like SSRIs."

8 / 10
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  • James...
  • January 6, 2020

For Seasonal Affective Disorder "I had used bupropion XL three years ago for SAD (seasonal affective disorder)and it helped. I started again this end of November 2019. After 4 weeks it started to work. I would recommend starting take the first week that Daylight saving time ends. November 1 or even before. It might be best to start taking when you notice that the days are getting shorter and it bother you. I intent to taper down the first week of March 8 as long as I feeling well. I can not say it help with ADD. I am taking 150mg extend release."

8 / 10
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  • Anonymous
  • October 20, 2011

For Depression "I have been on 200mg of buproprion xl for about 2 years and I can say that it has had a great effect on my life. First off, I quit smoking. The urge to smoke was like, GONE! My mood was great for about 1 1/2 yrs and I feel that this is a great medicine for most. I did gain weight on it and my appetite has actually INCREASED, so I guess I am one of the unlucky ones. I have noticed some withdrawal symptoms if I miss a dose, which is something else to consider. It has stopped being effective for me and I am concerned about raising my dosage due to the withdrawal symptoms I have experienced. I am constantly tired and lethargic and recently had a major depressive episode. "

6 / 10
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9 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.