User Reviews for Asenapine

Also known as: Saphris

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Ratings Summary

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10
   
36%(26)
9
   
26%(19)
8
   
17%(12)
7
   
5%(3)
6
   
5%(3)
5
   
3%(2)
4
   
3%(2)
3
   
2%(1)
2
   
2%(1)
1
   
7%(5)

Key Statistics

8.0/10 Average Rating

74 Ratings with 78 User Reviews

Compare all 69 medications used in the treatment of Bipolar Disorder.

Reviews for Asenapine to treat Bipolar Disorder

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Review by Anonymous: User Rating:  
   
10

Saphris (asenapine): Been on Saphris for about two months. Taste is bad but the benefits of medicine far outway that. Only side effect is slight numbness in mouth after taking pill but that goes away after about 30 minutes. No other side effects. Racing thoughts, shadows, voices, have now disappeared. First time that has happened in years. Have been able to decrease dosages of other medicines and wean off some all together. So far it has been a miracle drug for me. Feel better now than I ever have.

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March 1, 2010 4:16 PM
Review by viperman1029: User Rating:  
   
10

Saphris (asenapine): I have been severely depressed for six years after coming off my medications in May 2006, due to a bad manic episode. I have tried so many medicines, even the ones that worked before. Nothing could get me out of the dark hole I was in. I went to my Doctor and told him I wanted to try ECT therapy because I was suicidal. He set it up, but asked me to try a new medicine (Saphris) in the mean time. I was willing to try anything. He placed me on 5mg at night, and told me it would probably allow me to eliminate the Ambien for sleep problems. Man, did it. My wife noticed a difference in my mood the next day. I have been on it now for two weeks, and cross my fingers I have not felt this good for twelve years.

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April 3, 2010 3:01 PM
Review by Anonymous: User Rating:  
   
10

Saphris (asenapine): I have been on many Bipolar medicines, Lamictal, Seroquel, Geodon, lithium, also Xanax to help me sleep. I have been on Saphris for one week and started feeling better the next day. I will admit it tastes terrible, but my doctor told me the trick is to take a sweet tart with it, and it isn't so bad. Works for me. My dosage has gone from 5mg to 10 mg, but I'm getting the best sleep I've ever had except for some strange dreams, but I cant complain. The benefits outweigh the taste and dreams any day. I highly recommend this medicine (and a sweet tart!).

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May 20, 2010 2:09 PM
Review by sunlight_starbright: User Rating:  
   
10

Saphris (asenapine): I have been on a truck-load of different medicines to treat Bipolar, Lamictal, Depakote, Lithium, Seroquel, Symbyax, Abilify...just to name a few. Started taking this 10mg/before bed, last week. This does taste horrible, but doesn't cause nausea and vomiting and I'm real sensitive to taste. It makes my tongue go numb for about 30 minutes and during that time I get the munchies really bad. While I'm trying not to eat the house down my mood elevates. I've been getting to sleep a lot easier and staying asleep better. As a whole, I'm feeling better than I have in a long time. Really hoping this medicine works on the long-term for me as I'm tired of trying different ones.

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June 3, 2010 5:46 PM
Review by nandm: User Rating:  
   
9.0

Saphris (asenapine): It is like a light switch has been turned on. I finally feel "normal" for the first time in many years.

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March 10, 2010 1:57 PM
Review by johneconner: User Rating:  
   
10

Saphris (asenapine): Dissolves very quickly compared to other sub-lingual tablets that I have taken - tastes horrible though! I have experienced no negative side effects, and it has definitely elevated my mood and taken away the "shadows" and some of the "noises" that accompany my diagnosis....overall seems to be much better than the last two meds I was prescribed (Lamictal and Abilify). I give it a ten!

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February 22, 2010 1:06 AM
Review by Anonymous: User Rating:  
   
8.0

Saphris (asenapine): Taking 5 mgs AM & PM. Absolutely no side effects so far. Dosage is sublingual and the pill tastes horrible. Feel definite lift in spirits. Hasn't done much for the obsessions though.

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December 24, 2009 10:47 AM
Review by Anonymous:

Saphris (asenapine): I started 5mg Saphris 12 days ago and it's UNBELIEVABLE! 20 years ago (on my birthday) I was diagnosed with bipolar that worsened to include severe, treatment- resistant depression. I have done and seen it all - buckets of drugs, ECT and an experimental VNS implant. Mentally, nothing I've tried can touch this stuff! I have also experienced almost every severe physical side effect, and my ADHD-type behavior, noises and shadows are worse (hard to imagine) but I don't think I'll call my doctor on a Sunday. He just gave me 10 of the best days in memory (which is also returning). Will I give piano concerts again? Maybe - if I can play backwards, but I feel so good I could just stand in the corner for the rest of my life.

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April 25, 2010 8:57 PM
Review by Anonymous: User Rating:  
   
10

Saphris (asenapine): Saphris does not taste good; it leaves my tongue slightly numb. I've experienced no side effects so far in the 2 weeks I've been on it. I have experienced relief from symptoms from disorders.

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January 18, 2010 12:31 PM
Review by Roo Mueller: User Rating:  
   
9.0

Saphris (asenapine): I have Bipolar with depression, mood swings, panic attacks, racing thoughts, voices and suicidal tendencies thrown in with seizures. On top of all that I cannot sleep. I've tried just about all the medication out there for Bipolar but after a time they stop working. Saphris 10 MG, has worked miracles for me. All those symptoms are now gone with this fast acting pill. You can stop a panic attack within a minute or two. The down side is weight gain, it is a very bad side effect. Recently I had two packages that I had to take to the pharmacy because they just would not open. They had to break the finger tab and unlock the clip beneath it. Bad design but otherwise very happy with this medicine.

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August 24, 2010 1:32 PM
Review by Bullwinkle57: User Rating:  
   
8.0

Saphris (asenapine): I've been Bi polar for over 20 years and have tried practically every mood stabilizer and antidepressant there is and some would work for awhile then poop out. Saphris is like a miracle medicine. I don't feel depressed, I have more energy and motivation and my moods are stable. I take one 10 mg tab at bedtime and wake up the next morning feeling alive and ready for the day. I would encourage anyone who is suffering from bipolar depression and mood swings to give this medicine a try. You won't be disappointed. One caveat though is without insurance it is very expensive.

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December 3, 2010 2:25 PM
Review by Anonymous: User Rating:  
   
10

Saphris (asenapine): I was weary about taking Saphris, but it immediately helped with feelings of anxiety and depression. I feel more confident now and my thinking is less muddled.

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November 17, 2010 2:04 PM
Review by Anonymous: User Rating:  
   
1.0

Saphris (asenapine): Works great for sleep and controls mania well, but caused my depression to increase. This was after being on the medication for several months (10mg/night). Didn't particularly like the next-day hangover either. I've recently been switched over to Lithium but it's too early to tell how it's working. I took one Saphris tablet last night per doctor's request, after being off it for some time (as a sleep aid) but felt hung over and a bit depressed most of the day.

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May 22, 2010 2:10 AM
Review by Anonymous: User Rating:  
   
9.0

Saphris (asenapine): Saphris seems to really calm my manic symptoms. Especially the racing thoughts and restlessness. My doctor gave samples of the new Black Cherry Saphris and the taste is 1000 times better! It's almost pleasant tasting. And to top it all, I've only gained 3 pounds the 6 months I've been on it.

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January 24, 2011 11:26 PM
Review by Anonymous: User Rating:  
   
9.0

Saphris (asenapine): I've been on Saphris for a week now. 5mg/night. Here are my initial thoughts: I feel like it’s summer. It’s a good calmness. The mouth numbing was really bad at first when I took it, slowly getting less each day (it’s always gone by morning). I felt the first couple days like I had taken a Sudafed; very awake the next morning. That effect is also wearing off day by day. I have been taking it at bed so I ‘m not sure if it makes me dizzy still. I can think clearer. I’m sleeping like a log. I feel less cold. My sinuses feel wetter. I actually get hungry now. I feel super non-stressed out. I’m stretching better in my dance and my joints no longer crack. I feel normal again.

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January 31, 2011 4:34 PM
Review by Anonymous: User Rating:  
   
9.0

Saphris (asenapine): I have to say this is a great medicine for people to try especially if those having difficulty sleeping. I had mania and my highs and lows have become stable. I have been taking this for about a month and noticed a difference the next day. It does have an awful taste but it is worth the benefits. My cocktail currently for Bipolar 1 is Effexor XR, Depakote, Lamictal, and Saphris. I plan to ween off some of these medicines since Saphris has been working well. I have tried Abilify and Seroquel and had bad reactions.

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September 19, 2010 9:35 PM
Review by Geophory: User Rating:  
   
10

Saphris (asenapine): Doctor warned me it tasted bad. Understatement. HORRIBLE! Numbs my mouth but is tolerable. Noticed huge difference the next day. Mood is great but I slept for 12 hours after first taking it. I'm sure my body will get used to it and that will stop happening. I'm supposed to take it twice a day but can't unless I want to sleep 24 hours a day. I expect to take it twice daily once my body adjusts. No other side effects except taste and sleep. Didn't have to use Lunesta for first time in months.

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May 8, 2010 12:30 PM
Review by Patricia 2: User Rating:  
   
10

Saphris (asenapine): This medication has been a God send. Never felt better in 24 years since diagnosis...been on everything before. Saphris is amazing. Down side is dry mouth and water retention. Upside is everything else. Thank you Merck...you hit the target this time.

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October 9, 2010 3:18 PM
Review by Anonymous: User Rating:  
   
8.0

Saphris (asenapine): I have only been on this medicine for 3 days. It tastes very bad. Use a Listerine strip if you don't like the taste. It is not that bad for me. I take it twice a day, but I have to drink a pot of coffee in the morning so not to fall asleep. I feel better, not sure if it it is the coffee or the medicines. I do sleep very well with it. Haven't had this much sleep in years.

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June 12, 2010 8:35 PM
Review by Teresa333: User Rating:  
   
8.0

Saphris (asenapine): This is the third day and that's why I only rated it an 8. I was hypomanic with extreme swings and I've calmed down so much already.

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July 31, 2010 1:44 AM
Review by Anonymous: User Rating:  
   
6.0

Saphris (asenapine): I've been on Saphris about 2 weeks now and the nausea has been terrible, not sure how much longer I'll stick with it. I don't feel I've gotten any better, in fact. Not sure what to do next.

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March 12, 2010 10:37 PM
Review by Anonymous: User Rating:  
   
9.0

Saphris (asenapine): Started taking this a few days ago. The comment about the bad taste~ UNDERSTATEMENT, it tastes NASTY, but seems to be working well. I am currently on Seroquel 200 mg, temazepam 45mg, and Xanax as needed. I am dropping down on the Seroquel until I'm completely off. Horrible weight gainer, but does help. Since starting this, I have not taken ANY Xanax and I have energy during the day and it seems to curb my hunger.

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October 1, 2010 12:36 AM
Review by clbhrs54: User Rating:  
   
9.0

Saphris (asenapine): Felt better after first day, working on day 5 can't believe how super, great, wonderful, alert, and alive, I feel. After 27 years of fighting bi-polar disorder, I am amazed. Hope it lasts. No side effects so far, hasn't helped my grammar or spelling. Oh, taste? what taste?

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December 4, 2010 5:22 AM
Review by Zura: User Rating:  
   
10

Saphris (asenapine): I have been on Saphris for 6 months now. It tastes horrible, but it works to control my moods better than any other medicine I've tried. I have vivid dreams on Saphris and sometimes stiff muscles. I use Flexeril for that side effect. I have been improving greatly on this medicine. It also works quickly, I feel the effects soon after taking it. My dose is 10mg twice a day.

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November 2, 2010 1:50 PM
Review by Anonymous: User Rating:  
   
9.0

Saphris (asenapine): I was diagnosed 5 years ago with bipolar disorder. I was very wary of taking the protocol drugs including lithium. I was prescribed a boat load of all the usual drugs but had terrible side effects. I have been very happy on Lamictal and Celexa for the past several years but have problems with anxiety, edginess, racing thoughts and sleep. My doctor prescribed Saphris for me a week ago. I am amazed at how great I feel. Like others here, I finally am able to sleep. I also almost immediately felt better. My brain actually has slowed down. For me, it does cause very bad dry mouth and trouble swallowing which I counter with Evoxac. Otherwise, I finally feel great!

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December 2, 2010 3:48 PM
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