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Allopurinol User Reviews & Ratings

Brand names: Zyloprim, Aloprim

Allopurinol has an average rating of 7.4 out of 10 from a total of 87 reviews on Drugs.com. 64% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Allopurinol

  • SlowL...
  • October 22, 2018

For Gout "Developed noticeable gout symptoms at 35years old. Condition became progressively worse. Blood test showed my UA level to be 11.0! Was having frequent gout attacks due to lifestyle. Tried homeopathic and natural "cures" (GC, Cherries, Cherry Juice, etc) not much relief. Gout was moving into elbow, wrist, knee and thumb. Allopurinol has lowered my Us from 11.0 to 4.0. I have my life back. Waited and suffered too long fearing the potential side effects, of which I have had none. I'm a lifer now. What a difference."

10 / 10
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118 Report
  • TKE
  • October 22, 2013

Aloprim (allopurinol) for Gout "I have had experience with gout since1975. Anyone with similar experience knows by now the pain gout inflicts. There were early periods when my use of allopurinol was intermittent. This proved to not resolve the problem for me. Sine 1977, my daily use of allopurinol has resolved the problem. Hopefully others have had similar relief."

10 / 10
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151 Report
  • Joe
  • Taken for less than 1 month
  • April 12, 2021

For Gout "I was on Allopurinol for 3 weeks and I never felt worse in my life. This drug turned toe pain into severe joint pain in both my feet and hands. I had a headache, my entire body felt weak and I couldn’t stay awake. Allopurinol made me disabled & I lost my job. I was not able to walk or get out of bed. My doctor prescribed me more and more pain killers to help me tolerate a drug that my body wouldn’t. I skipped 1 dose of Allopurinol for 1 day and I felt completely back to my normal self. I stopped all the prescription drugs and It was like coming out of a fog. My toe hurts a little but I’m working on my diet, taking supplements to help get rid of the uric acid and I have never felt better. Praise god!"

1 / 10
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49 Report
  • Allop...
  • Taken for 2 to 5 years
  • September 27, 2013

For Gout "Spent a year in foot pain hell as one doctor after another misdiagnosed my gout. I was in a bad way, spending night after day after night in 10 out of 10 pain, wondering what the point was. I finally found a podiatrist willing to *listen* to my symptoms and put two and two together. After going on 300 mg allopurinol/day three years ago, I'm essentially symptom free with uric acid bouncing around 6.0. Like others on this board, I spend a couple of days a year with a slight stiffness in my arch. But otherwise I am functioning normally. I simply can't imagine going back to my life without Allorpurinol - truly a miracle."

10 / 10
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120 Report
  • Anonymous
  • August 10, 2008

Zyloprim (allopurinol) for Gout "This medication has been very very effective. I was almost debilitated with gout attacks and continued use of indomethecin. It only has one bad side effect for me and that is excessive sweating. Sometimes I will have hot coffee for breakfast and have to change my shirt afterwards. At times in public it is embarrassing. But it's a lot better than having a gout attack."

9 / 10
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158 Report

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  • Rocki...
  • Taken for 6 months to 1 year
  • February 11, 2016

For Gout "Started taking allopurinol at age 54 after trying to manage Gout through lifestyle and diet for 14 years. Adopted vegetarian diet, limited use of alcohol and was not overweight. What finally "cracked" me was a severe attack in one of my ankles, whereas previous attacks (about 1 / year) always struck the left toe joint. Attacks were typically prompted by severe exertion and dehydration. Uric acid level had crept up to 7.2 and stayed there. Started on a regiment of 300mg Allopurinol and 10mg/colchicine. It prompted an initial, minor flare-up, but none since. Stopped the colchicine after 6 months and am continuing the allopurinol 300mg once daily. Most recent uric acid level is 5.2 and have had no issues, or side-effects."

9 / 10
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  • Ciaran...
  • December 12, 2015

For Gout "First had gout at 38 - too much booze (about 50-60 units a week for years and years) plus a diet rich in oily fish. Didn't know what it was for a couple of years - diagnosed at age of 40, 18 months ago, and went on daily Allopurinol. Haven't had a twinge since. Am trying to drink less, albeit not very successfully - nevertheless, would recommend this drug 100%."

10 / 10
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91 Report
  • Anonymous
  • Taken for 10 years or more
  • July 2, 2012

For Gout "I got terrible gout and played ice hockey when it first appeared. I'd be out of the lineup for weeks. The Doc had me on various medicines... none worked. I read about Allopurinol on a web search, suggested it to him. Only time I feel the gout coming is when I forget my daily dose. It been 10 years of success with no side effects. "

10 / 10
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115 Report
  • dagen...
  • February 12, 2008

For Gout "I first started getting attacks of gout when I was 21. My first doctor told me to put my feet up. I decided after my third incapacitated week of illness to find a rheumatologist, who prescribed Allopurinol and Colcocine. I didn't experience the side effects, but I know I'll be on these pills the rest of my life. No problem, tho, because it beats having a gout attack! :) Allopurinol is a lifesaver!"

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131 Report
  • aero...
  • November 8, 2013

For Gout "30 year old male. had gout for 1 year. 1st attack so bad that it developed tophi in my big toe joint. Uric acid was 9.6 at the time. Made some diet changes but that only brought me down to 7.4. I have gout attacks quite often, but most are mild. Ive been on 100mg allopurinol for a month with no side effects. Uric acid is now 6.2 so I had my dosage increased to 200mg so I can get below 6. It is very important to get on daily colchicine (0.6mg twice a day) while starting allopurinol. I learned the hard way."

9 / 10
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92 Report
  • Valve...
  • August 26, 2015

For Gout "I used to get gout from age 60 on, sometimes very bad,used colchizine and voltaren. Cherries and avoiding carbonated drinks and seafood. Now I consume these w gusto. Am on Allopurinol for more than a year and feel fine but the skin on my face is rough, and I get more dandruff, A small price to pay for PAINLESSNESS. I am 77 now."

10 / 10
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77 Report
  • keagirl
  • Taken for less than 1 month
  • January 14, 2016

For Gout "I'd put ZERO, but probably won't show! 2 weeks after taking it I started to itch. PA should have taken me off. 4 weeks after start, my kidneys started to fail. 5 weeks after my face, hands, feet started to swell and flake. My Dr.'s investigated and I had a syndrome called DRESS, Drug Rash with Eosinophilia and Systemic Symptoms. Allopurinol is one of a handful of meds that causes DRESS. I've also read that it has an 8% mortality rate, which is MUCH too high!"

1 / 10
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69 Report
  • Profi...
  • Taken for less than 1 month
  • September 27, 2019

For Gout "I am 47 yrs old, 6’ tall and 183 lbs. I had some routine blood tests done to check cholesterol, PSA etc etc. They come back with high Triglycerides (561) and Uric acid at 8.4 so the MD has put me on Lipod for the Triglycerides and Allopurinol for the Uric acid even though I’ve never suffered from Gout. I must admit I like a few beers a night and my diet is mostly fish as I don’t eat meat. I’ve been on the combination of meds for a month now and I have lost all energy and maybe not depressed but I certainly don’t have the get up and go I used to have and my sex drive is pretty much zero."

5 / 10
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44 Report
  • Zacha...
  • Taken for 6 months to 1 year
  • September 30, 2015

For Gout "I suffered debilitating Gout foot pain, due to my love for animal-based protein. With Allopurinol daily, I can eat those foods again...just in moderation now. I am a fit, lean 51-year-old Mountain Biker, who rides 3-4x a week. Side effects are nighttime itchy arms and back. I hate taking any meds - but Allopurinol is cheap and now part of my daily dosing. I also had to stop taking daily Aspirin(325mg) as it was amplifying my Uric Acid levels."

7 / 10
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70 Report
  • Joe
  • Taken for 2 to 5 years
  • April 3, 2019

For Gout "While I haven't had any problem with gout since I started talking Allopurinol over 2 years ago, I HAVE struggled with erectile dysfunction and very low libido as a result of taking Allopurinol. Dr. even prescribed generic viagra and it has done no good. Stopping Allopurinol a while to test my hypothesis."

6 / 10
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  • Wizma...
  • October 22, 2013

For Gout "I've had undisguised symptoms for 20 year causing mild discomfort e.g. Uric acid buildup on earlobes. Chronic wrist pain. Moderate two attacks , all annoying but I never figured it to be gout or realize the horror about unleash itself on me at a fit 49 years old. I exercise, only about 10 lbs overweight and eat healthy. I was a heavy beer drinker though. Last year my left wrist and thumb swoll to the size of a red grotesque boxing glove. No pain medication could touch it. Imagine bone fracture pain with no relief. I was in chronic pain, depressed despondent and close to suicidal. Because I had ignored symptoms for so long the rheumatologist told me I had "entrenched" gout and the allopurinol was going to make it worse before it got better."

10 / 10
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79 Report
  • John
  • August 24, 2017

For Gout "41 year old male been dealing with gout for about 5 years now. At first I didn't know what it was I just started getting pains in my feet. Long story short it progressed into frequent attacks in my ankles with pain beyond belief. I tried all the natural remedies and they helped a little, especially cherry juice, but I was losing the battle. I've never been so depressed and I was literally going out of my mind. I finally started allopurinol per my doctor. 100mg at first then 200mg. At first I got more attacks for about a month. But then they subsided and I've been attack free since. God send. No side affects but maybe some dry skin. If you are suffering with this try this drug. It could save your sanity it did mine. Just remember it is better to start it between attacks (while you don't actually have gout) and your gout might get worse before it just goes away"

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  • Pete
  • November 4, 2020

For Gout "I'm 68. Have had chronic gout with tophi for over 15 years. Was experiencing debilitating gout flares at least twice a month. Couldn't walk during attacks with excruciating pain. Finally decided to take allopurinol 200mg daily as recommended by my doctor. Quit alcohol, red meat, HFCS containing foods/drinks, and drastically reduced sugar intake. During the first 18 months I continued to get severe attacks that only prednisone could relieve. After almost 2 years, my uric acid has gone down to 5.3 and have not gotten a severe attack in the last 6 months! It took a while but I had faith and continued taking my allopurinol even if it seemed like it wasn't working. FINALLY, I am enjoying being free from gout attacks and much happier! Allopurinol works. It just takes time."

9 / 10
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33 Report
  • Celia...
  • Taken for 5 to 10 years
  • June 17, 2013

For Gout "After a multi-year personal trial, it was found that if I consumed anything with Canola Oil it affected the efficacy of the allopurinol. As long as I take my daily 300mg and avoid Canola, then beef and beer (in moderation) are back in the diet. No full blown attacks in 18 months."

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  • Brian...
  • Taken for 1 to 6 months
  • April 12, 2016

For Gout "Am 56 and have suffered gout in miltiple joints since I was 20. Have tried every drug available with no great relief and a lot of side effects. Went onto allopurinol early 2016 and after some pain due to how allopurinol initially works I am pain free and it is great. No side effects so far. All of my tophi appear to have dissolved."

10 / 10
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  • Gout-...
  • Taken for 1 to 6 months
  • August 27, 2015

For Gout "First gout attack in big toe at 42 lasted two months. Couldn't wait to get on allopurinol. Started at 100mg for a week, then 200mg for a week, then 300mg steady. Also taking 0.6mg colchicine. UA went from over 10 to less than 5 in a month and no flare ups. Side effects include aching foot and fatigue, but overall it's definitely worth it."

8 / 10
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63 Report
  • jahtez
  • Taken for 10 years or more
  • June 30, 2017

For Gout "I experienced attacks of gout from my 20's on - debilitating pain in a foot joint being the most common symptom. I'd have half a dozen attacks of this per year lasting a few days. I finally went to a doctor in my early 30's and was put on a daily Allopurinol regime, and I haven't had an attack since. I'm currently in my mid 60's. Over the past 6 years I've significantly altered my lifestyle, dropped 60 lbs, exercise far more often, and no longer eat meat, so I'm considering asking my doctor if I should try going off the medication. But overall, it has been a blessing to me."

10 / 10
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  • stickin...
  • December 6, 2011

For Gout "Been on it for a year with no side-effects. My uric acid is consistently in the 6-7 range and the debilitating attacks have ended. However, I still do get the occasional stiffness in the arch of my foot as well as an infrequent bout with pain (although much less in intensity). Without it, I was crippled and bed-ridden during my frequent attacks. With it, I live a normal life."

9 / 10
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  • wreak
  • Taken for 1 to 6 months
  • November 27, 2018

For Gout "After 40 days on this med, my gout attacks are more frequent, more severe, and longer lasting. I can't walk or sleep for the pain. How could they sell a cure that causes the disease? I read it does make it worse at the start while body is getting rid of uric acid and the Doctor should only start it when the gout is clear or they should give something to treat the gout at the same time as you start. Once it starts working it should be great. They say the trick is to start at a low dose, get your uric acid levels checked and increase the dose slowly til your uric acid levels are good."

1 / 10
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  • nlangan
  • Taken for 1 to 6 months
  • February 3, 2018

For Gout "I am a middle aged male and have suffered from periodic gout since my late 20's. I get it in my big toe and the pain is so awful, even the strongest prescription pain killers only dulled it. It seems to be food triggered; in my case, beef and certain fish. Tried eating cherries, drinking pure cherry juice and several preventative medicines. This is the first medication I have taken that has actually worked. Side effects have been minimal. Five months and totally gout free, regardless of diet."

9 / 10
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45 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.