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Alendronate for Prevention of Osteoporosis User Reviews

Brand names: Fosamax, Binosto

Alendronate has an average rating of 2.2 out of 10 from a total of 56 reviews for the treatment of Prevention of Osteoporosis. 11% of reviewers reported a positive experience, while 84% reported a negative experience.

Alendronate rating summary

2.2/10 average rating

56 ratings from 58 user reviews.

Compare all 33 medications used in the treatment of Prevention of Osteoporosis.

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Reviews for Alendronate

  • painful
  • Taken for 1 to 2 years
  • April 22, 2023

Fosamax (alendronate) "After a freak accident where I slipped on a waxed floor and broke my hip, I was put on Fosamax for two years. However, my doctor eventually advised me to discontinue using it due to severe joint pain in my shoulders, neck, legs, feet, and back, as well as the development of TMJ and cramps in my feet. I also experienced tingling in my feet, hands, and arms, increased blood pressure, and three days of diarrhea every time I took the pill as prescribed once a week. I was always in pain and unable to sleep. Despite being an avid walker, I was unable to walk without pain. After being off the medication for two weeks, I am finally starting to get back to walking my 5 miles a day. I am hopeful that I will completely recover from the effects of the medication. In my opinion, the makers of this drug should provide compensation to everyone who has taken it."

1 / 10
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  • djack...
  • Taken for 1 to 6 months
  • February 1, 2023

Fosamax (alendronate) "I started taking Fosamax on November 11, 2022. I have only taken 11 doses and will NOT be taking any more. I was skeptical about taking this medicine after reading the reviews but my husband said that people who have positive outcomes normally do not post reviews-only people with issues post reviews, which made a little sense. I wish I had not listened to him and had gone with my gut feeling. After 6 doses, I started having numbness or pain in my teeth. It was such a strange feeling and I could not remember the reviews talking about pain in your teeth, so I continued the medicine, thinking I needed to see my dentist. After seeing my dentist and having no obvious issue, I researched the side effects again and have now discontinued the Fosamax. I am so afraid of how long the pain will last in my mouth and also these horrible headaches! I would never recommend this medicine to anyone!!!"

1 / 10
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  • Osteo...
  • Taken for 1 to 6 months
  • April 13, 2022

Fosamax (alendronate) "I started having a lot of soreness and pain in my right and left shoulders and forearms. It was terrible!! After reading all the horror stories I was very concerned. I stopped taking the drug immediately. (Was taking 1 pill every week). Starting reading reviews from all you good people, started taking 1 aleve and 1 advil (mini gels) in morning and before going to sleep. After a few days the pain started to subside. Feeling almost back to my normal self again! Never taking that stuff again. Taking calcium and D3. Hope this helps someone!!"

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Frequently asked questions

  • Bite...
  • March 6, 2017

Fosamax (alendronate) "Honestly the worst medicine ever. People who invented should be sued. I mean what we're they thinking????? It sent my mom to ER after 3 days and she was admitted for 8 days in hospital. She is still recovering. It will give you tons of pain all over your body, head, jaw, and more. It will make you unstable. I mean seriously the inventor of this medicine should be cursed the rest of his or her life. "

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  • Peaches
  • Taken for 1 to 6 months
  • July 29, 2013

Fosamax (alendronate) "Started taking June 2013, once a week. 4 weeks into taking started having headaches but didn't connect the dots. Then started having severe sharp pain in back and upper right behind rib cage. Pain so severe, went to ER, where they didn't know the cause (had my gallbladder removed 18 yrs ago). Finally spoke to my primary and the connection was made."

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Are you taking this medicine?

  • Tish
  • Taken for 1 to 6 months
  • November 16, 2019

Fosamax (alendronate) "I was prescribed Fosamax for osteopenia. I have taken a total of 6 doses. I had no side effects for the first 2 weeks. By the 3rd week extreme fatigue and headaches. I continued for another 3 weeks hoping symptoms would go away. When they didn't I discontinued taking it but a week AFTER I quit I developed severe bone pain, unbearable pain which is worse at night. I am taking arthritis drug to make the days bearable. SOMEONE PLEASE TELL ME THIS PAIN EVENTUALLY GOES AWAY!! I will be calling my Dr. on Monday."

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  • Fosaj...
  • Taken for less than 1 month
  • June 27, 2023

Fosamax (alendronate) "As of late June 2023, I have taken my third weekly dose. I am 77 years old and in excellent overall health. Within the first week, I became aware of some constipation, which I thought would dissipate but it persists. I have also developed slightly achy bones, mostly in my upper body, and a heavy feeling in my legs that has made my 2-3 mile walks more challenging. After reading all the negative reviews just now, I am going to stop the medication for a few weeks and see if I return to "normal." If "normal" returns, I shall dispose of the remaining doses and let my PCP know. It especially worries me that a number of reviewers who took Fosamax for a long time achieved only a small improvement in bone density. Not a good trade-off!"

3 / 10
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  • Maggie
  • Taken for 1 to 2 years
  • January 8, 2020

Fosamax (alendronate) "I took Fosamax for several months back in 2010 . My scan showed osteopenia. After those months I started to have severe bone pain in both legs .A large amount of my hair also fell out as well . . I stopped the Fosamax . The pain took about 6 months to stop . The hair stopped falling out and after a year returned to normal . Terrible experience ."

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  • redsox
  • Taken for less than 1 month
  • January 2, 2021

Fosamax (alendronate) "Prescribed Fosomax and took only ONE weekly pill and after 2 days I felt deep bone pain in my thigh, like drop you in your tracks pain. For 3 days after I truly thought I would have a thigh fracture - so I quit. Going the supplement route so we will see. If it works for you great-not for me."

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  • Tripn...
  • Taken for 1 to 6 months
  • May 15, 2020

Fosamax (alendronate) "I was diagnosed with osteopenia a few years ago after cancer treatment. Oncologist recommended Fosamax, but I took oral calcium and D instead. No improvement. I had a fall and suffered a severe mid foot fracture. A moth later another fall, fractured wrist. I started taking the Fosamax a couple months ago. Sometimes difficult to remember to take it before eating. I take the following day. I sit up for 30 minutes after. I have GERD, so I have been taking Pepcid for several years. So far none of the side effects experienced. I am hoping my bones become stronger, scared of falling again."

10 / 10
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  • Kim
  • Taken for 1 to 2 years
  • June 21, 2022

Fosamax (alendronate) "At age 47 my obgyn informed me I had "osteopenia" - the beginnings of osteoporosis. "It's hereditary," the doc said after I divulged in my medical Q&A the 'fact' that my mother, then 67, had been diagnosed with osteoporosis. He Rx'd Fosamax. Though skeptical (I was so young!), I picked it up at the pharmacy. Two weeks went by before I decided to just go ahead and take it. I took it at around 9:00 the morning of the 4th of July. I had guests arriving later that day. Around 10:00 a.m, my daughter and I walked several blocks to a 4th of July parade in town. While walking I felt a strange chemical-like cold/chilling sensation migrating up from my left knee up into my femur. I remember thinking, how odd, it's as if it's actually beginning to work - almost instantly?? By 3:00 that afternoon, when guests were due to arrive, I began to feel feverish, weak, exhausted. 102 temp, severe chills & nausea. Needless to say, I knew the Fosamax was to blame. Threw the remaining away & am SO glad I did! Fosamax For 'mild ostepenia' (I now contend there is no such thing)."

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  • LaVrn
  • Taken for 1 to 6 months
  • April 7, 2017

"Give me osteoporosis. Nothing worst than this! I could not get myself to take my weekly dose today. I have been taking Alendronate Sodium 1 month now. I feel so....bad. Today before taking it I decided to read the reviews on it. OMG, I identified with all. I have never had so much pain, bones, joints, jaw, feet, dry mouth and sore eyes. How can a company put out such a product? I am so glad for everyone who posted their reaction for this terrible drug."

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  • Cindy
  • Taken for 2 to 5 years
  • October 28, 2019

"I've taken 70 mg of Alendronate for over 4 years. Luckily, I did not experience any side effects. My bone density 2 years ago showed some improvement, although my doctor felt it should have been better. I had another bone density a month ago and my osteoporosis is worse, so basically I took this medication for nothing. He wants me on Prolia but those side effects really scare me. Guess I will increase exercise regimen to include weights and take a better calcium supplement and see if my bones get stronger that way."

5 / 10
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71 Report
  • jan
  • Taken for 2 to 5 years
  • January 14, 2024

"Male 52 years. Hurt my back lifting a ladder. Bad pain in back if sitting or standing for more than 20 minutes. First doctor put me on pain meds, but did not fix the problem. This went on for almost two years before I convinced my doctor to do a full check-up. Eventually found out I had low bone density in spine. Rest of my bones have normal bone density. Taking Alendronate 70mg once a week, with two calcium pills and 1 D3 vitamins pill every day. Started feeling better within a month. I could be sitting/standing/walking for an hour before feeling pain. Every month it went longer before feeling the back pain. Now after 3 years on the medication, I can be on my feet for 12 hours before feeling back pain. Have not felt any side effects."

10 / 10
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  • Anonymous
  • February 27, 2021

"I was taking Alendronate for 6 weeks, I started getting head aches the first day I took them which continued off and on. Lots of stomach & bathroom issues, by 3 week, explosive diarrhea terrible stomach pain. 4 th, 5th, & 6 th pill the joint pains started. Why I stayed on this long still makes me angry. I called my doctor and told him I'm not taking them. Now it has been 4 weeks since my last pill and I was woken up with jaw pain and when I got out of bed I could hardly walk for pain in my left ankle . Why is this stuff not taken off the market , I wish I had never taken it, hopefully side effects will stop soon."

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  • Rose
  • Taken for 2 to 5 years
  • February 5, 2024

"I was diagnosed with osteoporosis four years ago. I will be 75 this year and have been on alendronate for almost 3 years with no side effects at all. At my last bone scan, it showed a slightly worse reading for my bones and I will be getting another scan in a week. If the results show that there is no improvement, I will consult my doctor to discontinue the drug. I take 1000mcg of vitamin D3 every day but try to avoid calcium to prevent arterial blockages."

5 / 10
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  • Cat
  • Taken for less than 1 month
  • April 19, 2020

"Prescribed Alendronate and I took once a week for 4 weeks. I had side effects of severe joint pain and I could barely walk, did not put it together until I checked out side effects and then stopped taking it.t I old doctor I was also experiencing heart palpitations too, he said do not take any more, been off medication about a week now, have been feeling a pain in upper shoulder blade area, hope this go away soon,I will not take this ever again"

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  • GEB
  • Taken for 1 to 6 months
  • February 22, 2019

"I had a horrible side effects with Fosamax as well, shortly after I started the taking it I was having a lot of back pain then I started felt sick to my stomach and dead tired, had no energy at, I could barely get off the couch. I followed the instructions to a T as prescribed by my physician and pharmacy. I was tired for almost a month and after which time I spoke to my pharmacist about my side effects and she recommended I talk to my Dr about switching to Risedronate, which I did and he wrote a script for it so I started it by the afternoon my thighs hurt so bad I could hardly walk, it was almost like it attacked my muscles or something. I spoke to my pharmacist again and told her what was happening and she said that I was having side effects that may or may not go away. So between myself and my husband and my pharmacist we decided it was not worth what I was going through. This was 2 years ago and to this day I still have muscle/bone pain in my thighs!! Worst drug ever!!!"

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  • Penny
  • November 21, 2019

"I took 1 pill. I followed the instructions. It has been 10 days after 1 pill that I am STILL throwing up. My esophagus is raw. My stomach pain and bloating is horrible. Nothing helps. Severe headaches too. I wonder if my stomach is bleeding. I am at risk for that since bleeding ulcers at 19. I also have horrible back pain and pain in the hip bone. I wonder who would make a medicine so awful, that not living just to get away from the side affects would be a relief! Never ever again."

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  • Retired...
  • August 30, 2017

"I took one dose of this hideous drug. Within 24 hours I started experiencing horrible hip pain, then shoulder and back. I have been unable to go about my daily duties because I am overcome with pain and fatigue. It is a week today. When will this be out of my system?"

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  • Cindy...
  • Taken for 1 to 6 months
  • September 21, 2020

"I took 35 mg a week for 4 months and started to have ear ache and jaw ache, I stopped as soon as I found out that this is one of the side effects It has been 3 months now since I stop taking the drug but the ear pain and the trouble it caused is still around Stay away from this drug"

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  • adjrean
  • Taken for 1 to 6 months
  • November 4, 2018

"After 1 month of taking 35 mg of Alendronate, once a week, I had extremely severe constipation. Usually, eating salads and whole grain cereals keep me regular, but this constipation did not respond to any of those measures. I am 67 years old and was diagnosed with osteopaenia. I've received this same diagnoses for about 10 years. So far, exercising and a calcium supplement were apparently enough. A drug that makes me too sick to exercise seems counter-productive."

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  • nutmeg
  • May 25, 2020

"9 months from just 2 doses (35 mg/week) and I am finally recovered from the severe arm, hand, and shoulder pain it triggered. A factor in my adverse reaction to alendronate is likely that I was also taking PPI's, which I learned later amplify absorption. After the first dose, I noticed sharp pains in my fingers that came and went. After the second dose, the next day I had severe pain in my right forearm, which grew worse over the next few days. I switched to using my left arm, but then that forearm grew painful, too. (I also had a few cramps in my thigh muscles over the first few days, and some pain in the balls of my feet). Over the next few weeks my forearms slowly improved, but as I started using my arms more, I developed pain in my shoulders and fingers. With rest, everything slowly improved. Believing I was well at 5 months, I carried a heavy bag on my shoulder, which triggered 6 weeks of shoulder pain. Now, at 9 months, I'm finally okay."

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  • Angela
  • Taken for less than 1 month
  • August 31, 2019

"My bone density test said I had osteopenia so my doc prescribed weekly Fosamax. I took the first pill carefully following instructions to stay upright and no food for 30 minutes. Felt fine until two days later I couldn’t get a deep breath without coughing. Every time I talked, the coughing started. My throat felt like there was something lodged inside. I got a cold sore on my lip and three little sore spots on the roof of my mouth. Took my second pill the next week. Felt like throwing up, the coughing still constant and developed the worst headache. Went to the doctor the next day, diagnosing me with acid reflux and to stop take Fosamax ‘for now’. If I ever feel better, I’m not interested in going through this again."

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  • Candi
  • Taken for 1 to 6 months
  • October 14, 2018

"Took the once weekly pill for eight weeks. My quality of life is still suffering three months later. After eating, I become nauseous and vomit at least twice a day. Bone pain, jaw pain, dental issues (never had before), excruciating heartburn and indigestion, and an overall sickly feeling rounds out my symptoms. Stay away from this toxic medicine!!"

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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.