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When I started taking Humira in 2008, I was covered over 80% of my body. Took Humira, and it was at least 8 weeks (if not more) for any improvement on the plaque psoriasis, although I noticed big improvement in arthritis pain and stiffness.
Once it cleared, within 2 years it was again widespread. Finally I have been on it regularly for two years in addition to Methotrexate (without it I feel it in my knees and hands). I now only have no more than 5 spots here and there.
Very happy with it, and only side effect was 1 time liver function affected, but easily fixed with lesser dose of Methotrexate.
Review by Creaky man-89 (taken for less than 1 month):
I have had psoriasis since I was 15 and mild psoriatic arthritis since I was 20, now four years later my psoriasis started to flare up after nearly a three and a half year remission due to treatment and develop in all the old places with it came severe psoriatic arthritis. Over the course of four months I went from moving normally to being in severe nearly constant pain and walking with a cane. I went to my dermatologist to see about any treatments and she prescribed me Humira. The day after the first two pen treatment I was walking with little pain and within a week I didn't need a cane any more. So far the only side effect I have had was a mild headache after the injection. Humira essentially gave me my life back.
I have been on Humira for over 7 years. I first tried Remicade in 2001 and it was a miracle. I have had psoriasis since age 14 and Psoriatic arthritis since 1994 but symptoms of the arthritis since 1989. I was always a runner but gave that up in 1998 until Remicade. Remicade worked great for a few years but eventually your own body builds up antibodies to it and it stops working. I have tried 4 other biologic medicines but always come back to Humira one shot a week. Over the years it has stopped working as well but I notice the difference when I do not take my shot. Still pretty miserable but still able to work full time and take care of my family. The IL 17 inhibitors are coming out soon and they look very promising.
I am 23, got diagnosed with psoriatic arthritis last year. I been miss diagnosed with systemic yeast infection because of the psoriasis and took 10 weeks of anti fungal prescription medicine which didn't help of course because that's not what I had. I went to a different doctor and he sent me to a rheumatoid specialist and from there he introduced and prescribed me Humira and I took my 1st injection and the next morning I woke up and my joint pain, swelling and psoriasis greatly reduced.
Review by Desperate in HI (taken for 2 to 5 years):
First time on Humira was like a miracle, my arthritis was minimal & my psoriasis too but I felt "finally a cure" and it cleared everything up. After taking Humira for 2 yrs I missed 1 month of shots (had it in the freezer by mistake). I thought it'll be okay however, my psoriasis came back worse than ever. I went back on Humira hoping everything will clear again and it hasn't so now I'm in a limbo again should I stay or should I stop. Has anyone experience this and if so what have you done? PLEASE HELP.
My son was diagnosed with Juvenile Psoriatic Arthritis when he was in fourth grade. By the time he was finally diagnosed he was in a wheelchair and unable to move most of his major joints...even his jaw was affected due to the severe arthritis. Today I can say thanks to God, Humira, and monthly visits to Shriner's Hospital he has graduated from High School and is now in REMISSION!
14 users found this comment helpful.
Changed my life for better in terms of mobility but very prone to picking up viruses, had several infections after a hand operation as a result and get nausea, upset tummy and more tired than I used to but I'm walking and have low pain levels so worth it. My psoriasis is nearly gone.
17 users found this comment helpful.
Review by Anonymous (taken for less than 1 month):
I have been experiencing extreme pain since 2009 from psoriatic arthritis, tried methotrexate no luck, finally started Humira 72 hours ago and already no pain whatsoever. A lot faster than I ever expected. The injection is not bad at all, a very small needle with a slight sting, but I'll take a 5 minute sting over the pain I had any day. I have not had any side effects yet I will edit this post if I do in future. I found these post very helpful with my decision to start Humira so I though I would return the favor.
31 users found this comment helpful.
I'm 22 years old and I was only 19 when I got diagnosed with psoriatic arthritis. At first, I didn't know what was happening to me. I suddenly couldn't do my daily exercise because my knees, feet, arms, fingers, back and neck started to hurt so bad that it was difficult for me to get out of bed, not to mention getting down the stairs. Every rheumatologist appointment was turning into a torture session with the cortisone injections and liquid being removed from my knees. Methotrexate did not do me good, so my doctor finally decided to start filling papers for my Humira injection. 1st injection was last week and WOW! is all I got to say. I've never been so happy in my life. My mornings are painless and now I work 10 hours a day without any Tylenol or prednisone.
26 users found this comment helpful.
After a year if misdiagnosis I was eventually told I had Psoriatic Arthritis. It hit me quickly and within a year was in constant pain in my chest, hands and feet that prevented me walking far. I was 43 at the time. After years of NSAIDs I was put on Humira. What a difference, I am 99% pain free and the swelling has all but disappeared all within a month or so of taking, a miracle for me.
24 users found this comment helpful.
I have been using Humira for over two years now. My skin has cleared up and my joints are a lot better than what they were. I have had psoriasis all my life but it was something that I just had to live with, so now after 36 years to be able to move around without having to hover after myself is a blessing in it self. I went swimming with my husband and children a couple of months ago. For the first time ever I was able to put on a swim suit. It just goes to show that the things some people take for granted are the things that we struggle to do all our lives. Humira has given me my life back.
33 users found this comment helpful.
I have been on Humira for nearly a year now. At first my rheumatologist was having me inject myself every 14 days, but that was not as effective as we would have liked, so he upped it to every 10 days. I kept it that way for a couple months, but my pain still was bad sometimes. So now he has me injecting myself once a week. Overall I think I'm having some success with the Humira, but I still feel quite tired and have days when my hands and back hurt too much for me to perform my job at work and do things around the house. My finger nails look better, but I'm not sure if the Humira has the ability to help that. I did have clearing of some of the plaques on my skin, but recently I have noticed that they are returning again.
17 users found this comment helpful.
I am on Humira and this past Saturday made my 12th SC injection. There are some good and some not so good things that I can say about Humira. I was very hesitant to try any of the TNF or monoclonial antibodies due to some of the possible side effects I had read about. My Rheumatologist let me decide from 3 protocols and I chose Humira. I asked my rheumatologist which one he felt more comfortable with and his response was Humira, so that is how I made that decision. Prior to starting Humira, my energy level was "nil" because I had no energy whatsoever. I will say my energy level has improved a great deal but getting fibromyalgia now and this is miserable. I am 45 but at times I feel 60. Good luck to all!
19 users found this comment helpful.
Humira has given me my life back. It is truly a miracle drug. Since I have been using the pen it has been a lot easier to give myself the shot. It starts to take effect quickly for me and I feel like my age:28. Without it I have trouble getting on the toilet, walking at all, engaging in anything active is too exhausting and very painful. I will be on this medication for the rest of my life, that is until they find a cure!
25 users found this comment helpful.
I have been using Humira since October of 2009, I had a lot of swelling in my joints after the injection and redness, swelling and bruising. I have not noticed much difference. I have started not only the cartilage degeneration but it is affecting my bone also. We are about to try Simponi. Hopefully this will work.
16 users found this comment helpful.
Humira has literally been a miracle drug for me. I started a little over a month ago with the spring-loaded self-injecting pen. My Psoriatic Arthritis manifests similarly to Ankylosing Spondylitis and it usually takes me several hours in the morning to get ready. I also had psoriasis covering my scalp since I was 15 or so. Notice I said "had". My psoriasis is almost entirely gone, and I get up in the morning the same as any other person. I also had a pronounced stoop forward, and my girlfriend was in tears of joy last night after we both noticed I was standing almost completely straight.
29 users found this comment helpful.
Was using HumiraPen for a few years. At first I was thrilled because it cleared up the psoriasis almost overnight. Made everything else more bearable within reason except for Lupus and Fibromyalgia. But ... in 12/08 I had a small boil that was handled as needed. One week later I was found unconscious and in septic shock. That boil blew a 4 inch hole in my side. Hospital records talked of Necrotizing Faciitis/MRSA ! My rheumatologist told me that the Humira suppressed my system so much that I had no warning of such a severe infection. I had no inflammation, fever or symptoms of any kind. BE CAREFUL...watch for the smallest skin lesion.
38 users found this comment helpful.
Experienced allergy symptoms from this (itchy eyes, sinus pain/running nose, etc.). Also had what the doctor called an allergic reaction to the shot on my leg. Started swelling up, and got bigger than the palm of my hand. Red, horrible looking, and it hurt to touch.
11 users found this comment helpful.
This drug is worth every penny for those of us who have endured shear pain for years. I feel like a human being and not a test rat for goodness knows how many medications that could just as well have been a placebo.
14 users found this comment helpful.
13 INJECTIONS SO FAR, my blood work looks better on some of my visits. I have allergy like symptoms continually which are nuisance, runny nose, itchy eyes, etc. I am sitting here in pain, and fibromyalgia aggravates everything. I wish something would make me feel better completely.
15 users found this comment helpful.
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