Clinical Trial Results Archive

Clinical Trial Results: November 2009

November 2 Alnylam Presents New Pre-Clinical Data on ALN-TTR, an RNAi Therapeutic for the Treatment of Transthyretin-Mediated Amyloidosis
November 2 Avila Presents Data on Its Novel, Orally-Available Protease Inhibitor, AVL-181, Demonstrating Viral Clearance of Hepatitis C Virus in Preclinical Models
November 2 Salix Pharmaceuticals Reviews American Association for the Study of Liver Diseases Annual Meeting
November 2 Dynavax's HEPLISAV Shows Increased Protection Rate for Chronic Kidney Disease Patients
November 2 Results from two Canadian studies confirm sustained viral response rates seen in hepatitis C patients treated with Pegatron
November 2 Novobiotics - Positive Initial Phase IIa Data
November 2 GlobeImmune's Hepatitis C Therapeutic Vaccine Combined with Standard of Care Increases End of Treatment Response Rate by 15%
November 2 Genta Announces Top-Line Results of AGENDA Phase 3 Trial of Genasense in Patients with Advanced Melanoma
November 2 Æterna Zentaris Announces Positive Preliminary Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Ovarian Cancer
November 2 Investigational Sublingual Allergy Immunotherapy Tablet Meets Primary Endpoint in a Study of Adult Subjects With a History of Grass Pollen Allergies
November 2 Human Genome Sciences and GlaxoSmithKline Announce Positive Results in Second of Two Phase 3 Trials of Benlysta in Systemic Lupus Erythematosus
November 2 Data Supporting Boceprevir Response Guided Therapy Presented at American Association for the Study of Liver Diseases (AASLD) Annual Meeting
November 2 Large Study of Anemia Treatment in Chronic Kidney Disease Patients Not on Dialysis Published in the New England Journal of Medicine Failed to Meet Primary Efficacy Endpoints
November 2 Zosano Pharma, Inc. to Provide Pipeline Updates at the 2009 AAPS Annual Meeting
November 2 UCL (University College London) Liver Failure Group Present Two Studies on a Novel Treatment Option (OCR-002) for Complications of Hyperammonemia in Liver Failure at the 60th Annual AASLD Meeting
November 2 Twice Daily Oral Medication Shows Promise in Treating Patients with Hepatitis C
November 2 YM BioSciences reports positive nimotuzumab four-year survival data presented at ASTRO 2009
November 2 Enzo Biochem Reports on Favorable Clinical Trial of EGS21 for Treatment of Non-Alcoholic Steatohepatitis
November 2 Gilead Announces Long-Term Data from Two Pivotal Phase III Studies Evaluating Viread For Chronic Hepatitis B
November 2 Bristol-Myers Squibb and ZymoGenetics Present Final Phase 1b Results for PEG-Interferon Lambda in Hepatitis C
November 2 BARACLUDE (entecavir) Demonstrated Greater Antiviral Efficacy Compared to Adefovir in New Study of Chronic Hepatitis B Patients with Evidence of Decompensated Cirrhosis
November 2 FibroGen Announces New Research in Anti-CTGF and HIF-PHI Therapeutic Development Programs in Kidney Disease
November 2 NovaBay's Aganocides Show Penetration and Efficacy in a Pre-Clinical Infected Human Nail Model of Onychomycosis
November 2 Schering-Plough Reports Potent Antiviral Activity With Narlaprevir (SCH 900518), an Investigational, Once-Daily Protease Inhibitor for Hepatitis C
November 2 Mayo Clinic Proceedings Publishes Study of NUVIGIL in Patients with Shift Work Disorder
November 3 Sanofi Pasteur Presents Safety Data on Menactra Vaccine Given to Infants at Infectious Disease Society Meeting
November 3 Study Finds Lack of Diffusible VEGF Growth Factor Can Cause Retinal Defects Similar to Dry Macular Degeneration
November 3 Idera Pharmaceuticals Presents Preclinical Data on IMO-2125, its Lead Drug Candidate for Chronic Hepatitis C Virus Infection, at Liver Meeting 2009
November 3 MagForce Nanotechnologies AG reaches primary study endpoint in pivotal glioblastoma study
November 3 SCYNEXIS' SCY-635 Demonstrates Positive Antiviral Activity in Combination with Approved and Investigational Anti-HCV Agents
November 3 ARIAD's AP24534 Featured in Cancer Cell Publication as a Potential First-in-Class Pan BCR-ABL Inhibitor
November 3 Ironwood and Forest Announce Positive Linaclotide Results from Two Pivotal Phase 3 Trials in Patients with Chronic Constipation
November 3 INFORM-1 Results: Robust Antiviral Suppression Achieved with Combination of Nucleoside Analog Polymerase Inhibitor RG7128 and Protease Inhibitor RG7227
November 3 Data for EntreMed's ENMD-2076 to Be Presented at the Upcoming AACR-NCI-EORTC Conference
November 4 New Phase IIa data on TMC435 in patients with hepatitis C presented at the ongoing AASLD - meeting
November 4 Long-term Outcomes Data Validates the Utility of PROSTASCINT in Guiding Targeted Prostate Cancer Treatment and Predicting Disease Free Survival
November 4 Promedior Announces Publication of Preclinical Studies in Science Translational Medicine Demonstrating that hSAP Inhibits Kidney Fibrosis
November 4 Aeolus Pharmaceuticals' AEOL 10150 Protects Lungs Against Chlorine Gas Exposure in Animal Studies
November 4 New Data on Attention in Children with ADHD
November 4 Concerta in the Classroom: New Data on Attention in Children With ADHD
November 4 Thirteen Abstracts Featuring Exelixis Compounds Accepted for Presentation at the 2009 AACR-NCI-EORTC International Conference
November 5 Alnylam Presents New Pre-Clinical Data on RNAi Therapeutics at Oligonucleotides Therapeutics Society (OTS) Meeting
November 5 Significantly More Smokers With Mild-To-Moderate COPD Quit Smoking Using CHANTIX/CHAMPIX (Varenicline) Compared With Placebo
November 5 Chelation Therapy Drug Found Safe and Beneficial for Children With Autism
November 5 Short-Term Hormone Therapy Added to Radiation Increases Survival for Medium-Risk, But Not Low-Risk, Prostate Cancer Patients
November 5 BioVex Announces Publication of Phase 2 Melanoma Results With OncoVEX (GM-CSF) in the Journal of Clinical Oncology
November 5 Ocera Therapeutics Presents Clinical Data Demonstrating AST-120 Relieves Pruritus in Patients with Liver Cirrhosis at the 60th Annual AASLD Meeting
November 5 Amgen Announces Overall Survival Results for Vectibix in First-Line Metastatic Colorectal Cancer
November 5 Approved Lymphoma Drug Shows Promise in Early Tests Against Bone Cancer
November 5 M. D. Anderson News Release: Early Stage, HER2 Positive Breast Cancer Patients at Increased Risk of Recurrence
November 5 New Safety Data on Menactra for Infants
November 5 Journal Cancer Publishes Pivotal Study of TREANDA in Patients with in Relapsed Indolent NHL
November 5 New Data on Bendamustine Offers Hope to Non-Hodgkin's Lymphoma Patients Resistant to Standard Therapy
November 5 Valeant Pharmaceuticals Highlights Taribavirin Phase IIb End of Study Data Presentation at American Association for the Study of Liver Disease (AASLD) Annual Meeting
November 6 ZIOPHARM Presents Positive Palifosfamide Sarcoma Randomized Phase II Interim Data at Annual Meeting of the Connective Tissue Oncology Society
November 6 Oncolytics Biotech Inc. Collaborators Present Positive Phase II Sarcoma Trial Results at CTOS Annual Meeting
November 6 Intarcia Therapeutics, Inc. Presents Positive Results from Two Studies of ITCA 650 for the Treatment of Type 2 Diabetes at the Ninth Annual Diabetes Technology Meeting
November 6 NexBio Publishes Two Articles Showing DAS181 (Fludase) Potently Inhibits Pandemic Influenza A(H1N1) and NAI-Resistant Influenza Viruses
November 6 Chimerix Updates the World Health Organization and the Global Health Security Initiative on Development of CMX001 as a Broad-Spectrum Therapeutic for Smallpox
November 9 BrainStorm Stem Cell Therapy Treatment Shown To Be More Effective Than Other Current Potential Stem Cell Treatments
November 9 ISTA Pharmaceuticals Highlights Bepreve Clinical Data at the 2009 Annual Meeting of the American College of Allergy, Asthma & Immunology (ACAAI)
November 9 Pandemic 2009 Influenza Update: Pandemrix data on co-administration with annual seasonal influenza vaccine (Fluarix)
November 9 Æterna Zentaris: Scientific Article Supports Perifosine?s Development in Kidney Cancer
November 9 Halozyme Study Results Demonstrate Significantly Less Absorption Variability for Insulin Lispro Administered with PH20 Enzyme
November 9 Zosano Pharma, Inc. Announces Publication of Positive Phase 2 Study of Its ZP-PTH Patch for Osteoporosis Therapy
November 9 DX-88 (ecallantide) Demonstrated Relief of Symptoms in Hereditary Angioedema Acute Attacks in All Attack Locations
November 9 CEL-SCI Collaborators Present Data Suggesting That LEAPS Technology Has Ability to Modify Immune Response
November 9 OssulinTM, a Novel Oral Insulin Product, Shows Promising Bioavailability for Advancing Diabetes Therapy
November 9 NexBio Presents Data Showing Anti-Asthma Activity of DAS181 (Fludase(R)*) at ACAAI 2009
November 9 SuperGen Presentations at AACR-NCI-EORTC
November 10 ImmunoGen, Inc. Announces Presentations at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
November 10 Roche reports positive Phase II results with potential first-in-class treatment for the negative symptoms of schizophrenia
November 10 Avanir Pharmaceuticals Announces Zenvia Safety and Efficacy Data from Star Trial Open Label Extension
November 10 Cytos Biotechnology updates on the development of the hypertension vaccine CYT006-AngQb
November 10 Labopharm's novel trazodone formulation subject of publication in peer-reviewed medical journal
November 10 Independent Study Utilizing Cyclic Levulan PDT Finds 95 Percent Reduction in New Squamous Cell Carcinoma Lesions in Solid Organ Transplant Recipients Over a 2-Year Period
November 11 Crinone 8% (progesterone vaginal gel) As Effective as Hormone Injections During IVF? Is Medscape's ?Top News? from The ASRM 65th Annual Meeting
November 11 More Than 200 Abstracts Evaluating Celgene Products across a Range of Indications to Be Presented at the 51st American Society of Hematology Meeting
November 11 Geron Collaborators Publish Data on hESC-Derived Glial Progenitor Cell Therapy in Cervical Spinal Cord Injury
November 11 DUSA's Levulan PDT found to reduce squamous cell carcinomas by 95% in solid organ transplant recipients
November 11 BioClinica to Host Medical Imaging Symposium for Rheumatoid Arthritis Clinical Trials on November 18, 2009
November 11 NanoViricides, Inc. to Present Anti-Influenza Drug Candidate FluCide Studies at the Influenza Congress 2009
November 11 Avanir Pharmaceuticals Announces Zenvia Safety and Efficacy Data from Star Trial Open Label Extension
November 11 Drugs to Treat Anemia in Cancer Patients Linked to Thromboembolism
November 11 Video: Sanofi Pasteur Announces Final Results of U.S. Clinical Trials of Influenza A (H1N1) Vaccine in Adults and Children
November 11 Viron to Present Data from Phase II Trial at American Heart Association Conference
November 11 Landmark Study in The Lancet Oncology Shows Capecitabine (Xeloda) Combination Therapy Reduces Early Breast Cancer Recurrence
November 12 Mersana Therapeutics Publishes Review Article Detailing Advantages of its Lead Cancer Compound in Journal of Advanced Drug Delivery Reviews
November 12 Shire Reports Findings From an Analysis Examining Emotional Lability in Children With ADHD Taking Vyvanse(R) (lisdexamfetamine dimesylate) Capsules CII
November 12 BioAlliance Pharma Presents Results for Its New Oral Chemotherapy Nanoparticle Innovation at the AAPS Annual Meeting in Los Angeles, November 8 to 12, 2009
November 12 Holllis-Eden to Present Interim Data From Its Phase I/II Clinical Studies of Apoptone (HE3235) at Molecular Targets and Cancer Therapeutics Conference
November 12 Pharmacyclics Announces Poster Presentations and Clinical Update at the 51st Annual Meeting of the American Society of Hematology
November 12 Lexicon Announces Positive Phase 2 Results of LX1031 in Non-Constipating Irritable Bowel Syndrome
November 13 BioTime CEO Dr. Michael West to Present at Stem Cells USA & Regenerative Medicine Congress 2009
November 13 Cleviprex Results Reported From Study in Patients With Intracerebral Hemorrhage
November 16 Poniard Pharmaceuticals Announces Pivotal Phase 3 SPEAR Trial of Picoplatin in Small Cell Lung Cancer Did Not Meet Primary Endpoint
November 16 Alkermes Announces Positive Results from Phase 3 Clinical Study of Naltrexone for Extended-Release Injectable Suspension for the Treatment of Opioid Dependence
November 16 Genta Announces Results of AGENDA Phase 3 Trial of Genasense in Patients with Advanced Melanoma
November 16 Addex ADX10059 Monotherapy is Effective on GERD Symptoms in Phase IIb Clinical Trial
November 16 Gentium Announces Presentation of Defibrotide Clinical Data at the American Society of Hematology Annual Meeting
November 16 BioInvent and ThromboGenics Complete Phase I Patient Trial of Anti-PlGF Cancer Therapeutic TB-403 in Patients with Advanced Solid Tumours
November 17 Novartis Influenza A(H1N1) 2009 vaccine US interim data show lower doses of antigen may suffice to generate a protective immune response against A(H1N1)
November 17 NicOx - NCX 6560 meets primary and secondary objectives in first-in-man study
November 17 Ticagrelor (BRILINTAT) Demonstrated Greater Efficacy Over Clopidogrel in the Most Urgent Clinical Setting
November 17 The Medicines Company Announces Positive Phase III Data in Two Late-Breakers at AHA and in NEJM
November 17 Shire Announces Publication of Open-Label Study on Coadministration of INTUNIV (guanfacine) Extended-Release Tablets with Stimulants
November 17 Data from Mipomersen Phase 3 Trial in hoFH Patients Presented at AHA
November 17 Oncolytics Biotech Inc. Collaborators Present Positive Phase I/II Trial Results in Advanced Solid Cancers with a Focus on the Head and Neck at the AACR-NCI-EORTC Meeting
November 17 American Heart Association Late Breaking Clinical Trial Report: Treatment for Iron Deficiency Improves Symptoms, Functional Capacity and Quality of Life in Chronic Heart Failure Patients
November 17 Poniard Pharmaceuticals Announces Updated Positive Clinical Data from Phase 2 Trial of Picoplatin in Colorectal Cancer and New Phase 1 Cardiac Safety Trial Results
November 17 AVEO's Triple VEGF Receptor Inhibitor Tivozanib in Combination with mTOR Inhibitor Demonstrates Anti-tumor Activity and Tolerability in Advanced Kidney Cancer; Preliminary Results Presented at AACR-NCI-EORTC Meeting
November 17 ImmunoGen, Inc. Announces Encouraging Clinical Data with Its IMGN901 Compound in the Treatment of Merkel Cell Carcinoma
November 17 Exelixis Reports Encouraging Phase 1 Data for the PI3K Inhibitor XL147 (SAR245408) in Combination with Paclitaxel and Carboplatin at the AACR-NCI-EORTC Conference
November 17 Interim Phase 2 Survival Data for PV-10 Will Be Presented by Professor John F. Thompson, MD, on November 21, 2009
November 17 Merck's Investigational Anacetrapib Phase IIb Study Results Presented at American Heart Association Annual Scientific Sessions
November 17 NeoPharm Presents the Phase I Data for Patients with Metastatic Solid Tumors
November 17 Higher Dose of Merck's Cozaar (losartan potassium tablets) Significantly Reduced Deaths and Hospitalizations Due to Heart Failure In Investigational Study
November 17 Pluristem Therapeutics Announces Three Month Follow-Up Data from the First Patient to Receive PLX-PAD
November 17 Aegerion Pharmaceuticals Announces Additional Lomitapide (AEGR-733) Phase III Data Demonstrates Significant Lowering of LDL Cholesterol with Promising Safety Profile
November 17 BioSante Pharmaceuticals Comments on Boehringer Ingelheim Clinical Test Results in Treatment of Female Sexual Dysfunction
November 17 Semafore Pharmaceuticals Announces Phase I Data Presentation Highlighting Novel PI3K Pathway Inhibitor at 51st ASH Annual Meeting
November 17 American Heart Association Late Breaking Clinical Trial Report: High Dose of Angiotensin Receptor Blockers Effective in Heart Failure Patients
November 17 YM Biosciences Reports Cyt997 Oral Vascular Disrupting Agent Results Presented At AACR-NCI-EORTC Meeting
November 18 Genzyme Announces Results of Phase 2/3 Trial of Advanced Phosphate Binder
November 18 Alnylam Presents New Pre-clinical Data on ALN-VSP, an RNAi Therapeutic for the Treatment of Liver Cancer
November 18 Results From Phase 2b Study on Atrial Fibrillation Agent Reviewed at American Heart Association
November 18 ImmunoGen Announces Encouraging Clinical Data with Its IMGN901 Compound in the Treatment of Merkel Cell Carcinoma
November 18 Genzyme Announces Results of Phase 2/3 Trial of Advanced Phosphate Binder
November 18 Viron reports positive Phase II data in Acute Coronary Syndromes (ACS) patients
November 18 Threshold Pharmaceuticals Presents Interim Prostate Cancer Data From Early Stage Trials of TH-302
November 18 Zydena is Efficacious in Once Daily Dosing for Erectile Dysfunction/Positive BPH Results
November 18 Cardiovascular Outcomes with Ezetimibe and Simvastatin Similar to Statin Alone, Claims Data Suggest
November 18 Exelixis Reports Encouraging Phase 1 Data for the PI3K Inhibitor Xl147 (SAR245408) in Combination with Erlotinib at the AACR-NCI-EORTC Conference
November 18 Peregrine Pharmaceuticals Presents Promising Antiviral Data at 2009 Chemical and Biological Defense Science & Technology Conference
November 18 Results From Two Phase II Trials Add to Understanding of Ticagrelor (BRILINTA(TM)) and How it Works in the Body
November 18 Sangamo BioSciences Provides Update on Phase 1 Safety Trial of SB-728-T for HIV/AIDS
November 18 Synta Presents New Data on Mechanism of Action of Elesclomol at AACR-NCI-EORTC Conference on Molecular Targets and Cancer Therapeutics
November 18 Synta Presents Preclinical Data on Next Generation Hsp90 Inhibitor, STA-9090
November 19 Geron Presents Interim Clinical Data on Its Telomerase Inhibitor Drug at AACR-NCI-EORTC
November 19 Medivir: Epiphany Biosciences Announces Positive Results from Its Phase 2b Trial in Shingles
November 19 Basilea presents new research data on oncology drug candidate BAL27862 at international cancer conference
November 19 ImmuPharma announces Positive Ph2b Lupuzor trial results
November 19 Epiphany Announces Positive Results from Its Phase 2b Trial in Shingles.
November 19 VIVUS Announces Positive Results From Phase 3 Study of Avanafil in Erectile Dysfunction; Data Demonstrate Robust Efficacy, Favorable Side-Effect Profile
November 19 Positive Results from Chronic Study with Bayer ?s Rivaroxaban Will be Presented As a Late Breaker at ASH 2009
November 19 Military Study Shows Prevention of Novel A/H1N1 Virus Infection is Vaccine-Type and Age-Dependent
November 20 Inovio Biomedical Universal Flu Vaccines Demonstrate Broadly Protective Immune Responses Against Multiple Seasonal & Pandemic Influenza Viruses in Pre-Clinical Studies
November 20 Ligand Presents New Preclinical Data on its Lead SARM Molecule LGD-4033 at the Gerontological Society of America Annual Meeting
November 20 Genasense Given as High-Dose IV Infusion with Chemotherapy Shows Promising Activity in Advanced Melanoma

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