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February 2007

February 14

Peregrine Pharmaceuticals Reports Positive Phase Ib Results for its Targeted Immunotherapy Bavituximab in Chronic Hepatitis C Infection Genta Cites Publication of Study Showing Improved Outcomes in CLL Patients Treated With Genasense Plus Chemotherapy Clinical Data Supporting Development of ChemGenex's Ceflatonin in Imatinib-Resistant CML Published in Cancer Morria Biopharmaceuticals Plc. Announces Publication of the Results of Its Human Pilot Study in Contact Dermatitis Patients of MRX1, a Novel First-in-Class MFAID Study Assesses New Communication Techniques Designed to Improve Dialogue About Migraine Between Healthcare Professionals and Patients New Instrument Developed to Measure Impact of Migraine on Patients' Lives When They Are Not Experiencing an Attack Protein Sensor for Fatty Acid Buildup in Mitochondria Genta Cites Publication of Study Showing Improved Outcomes in CLL Patients Treated with Genasense Plus Chemotherapy Hemispherx Avian Flu Prevention/Treatment Program Announces New Primate Results and Expands in both Europe and Southern Hemisphere Halozyme Therapeutics and Baxter Present Promising Results for the Use of Hylenex From the Infuse-Morphine Study

February 15

The Immune Response Corporation's Interim Phase II Data Suggest Both REMUNE and IR103 Stabilize CD4+ Cell Counts in Drug-Naive HIV Patients Unique Structure of Geron's Telomerase Inhibitor Drug Promotes Anti-Tumor, Anti-Metastatic Activity in Lung Cancer Cells Alagebrium Demonstrates Cardiovascular Activity in Recently Published Report Indicating Potential Wide-Ranging Benefits in Cardiovascular Diseases Positive Results with Lacosamide in Diabetic Neuropathic Pain in Phase III Trial Survey Finds Perceived Risk of Recurrence is Low in African American Breast Cancer Survivors Gene Network Sciences and UCSD Researchers Discover Connection Between Metabolic Pathways and Cancer Nasal Flu Vaccines Provide 'Double' Immunity, Carrington Labs Says CDC Report Provides First State-Specific Data on Persons Living With Heart Disease Researchers Discover New Details About HIV-1 Entry and Infection OXiGENE Announces Positive Results from its Phase II CA4P Clinical Trial in Myopic Macular Degeneration (MMD-213)

February 20

Auxilium Announces Results from Phase III Trial that Show AA4500 Successful in Treating Dupuytren's Contracture Vyteris Releases Study Estimating the Market for Lidosite Between $200M - $500M for Use Prior to Blood Draws Alteon's Investigational Drug Alagebrium Demonstrates Ability to Improve Functional Membrane Transport in a Rat Model of Chronic Peritoneal Dialysis, Indicating a Potential Role in Kidney Disease Basilea Reports Positive Phase III Results for Alitretinoin BioMarin Announces Results From Phase 2 Clinical Study of 6R-BH4 in Poorly Controlled Hypertension CeNeS Pharmaceuticals plc Announces Successful Phase III Results on Lead Product M6G Psoriasis Foundation Consensus Statement Examines Psoriasis Severity in a New Light H. Lee Moffitt Researchers Discover Potential Targets to Reduce Risk of Stem Cell Transplants New Data Support AlphaVax's Vaccine for CMV The Medicines Company Supports Landmark Patient Observational Study and Clinical Survey on Acute Severe Hypertension Researchers Funded by The Leukemia & Lymphoma Society Studying Agent to Target Gene Linked to Many Forms of Lymphoma RNAi Shows Promise in Gene Therapy, Stanford Researcher Says Stanford Q&A: Largest-Ever Study Shows Possible Genetic Links for Autism Successful Phase III results announced on Lead Product M6G FDA Warns About Erythropoiesis Stimulating Agents (ESAs) - Results of Aranesp Study May Apply to Other ESAs Largest-Ever Search for Autism Genes Reveals New Clues

February 22

Cell Genesys and Medarex Announce Encouraging Follow-Up Results from a Phase 1 Combination Therapy Trial With GVAX Immunotherapy for Prostate Cancer and Ipilimumab (MDX-010) Antibody Hollis-Eden Pharmaceuticals Presents Additional Positive Data with Novel Steroid Hormone in Models of Prostate and Breast Cancer Poniard Pharmaceuticals Announces Picoplatin Abstract Accepted for Publication by ASCO's 2007 Prostate Cancer Symposium Cell Genesys and Medarex Announce Encouraging Follow-Up Results from a Phase 1 Combination Therapy Trial With GVAX(TM) Immunotherapy for Prostate Cancer and Ipilimumab (MDX-010) Antibody Analysis of International Phase III Study of Avastin Plus Chemotherapy Shows Improved Progression-Free Survival in Patients With Advanced Lung Cancer Allegiance Equity Corporation Announces Positive Results of In Vitro Studies and an Open Label Trial for Relieva in Treating Atopic Dermatitis MediciNova to Present Phase II Clinical Trial Results for MN-001, a Novel Oral Treatment for Bronchial Asthma, at the 2007 AAAAI Annual Meeting CureDM, Inc. Achieves Two Drug Discovery Milestones

February 23

GTx's ACAPODENE Interim Bone Mineral Density and Lipid Data Highlighted at Press Briefing at Prostate Cancer Symposium of the American Society of Clinical Oncology Spectrum Pharmaceuticals Announces Satraplatin Data Presentation at the American Society of Clinical Oncology Prostate Cancer Symposium Satraplatin Shown to Significantly Reduce Risk of Disease Progression in Advanced Hormone-Refractory Prostate Cancer Patients Significant Phase III Results With Cimzia in Rheumatoid Arthritis Defibrotide Highlighted in Presentation at the 51st Meeting of the German Society for Thrombosis and Hemostasis Update on Cortex's CEO Presentation at the Roth Capital Partners 19th Annual Conference Crutchfield Dermatology Reports a New Wrinkle in the Quest for Smooth and Youthful Skin Dynavax Reports Interim, One-Year Data From Ragweed Allergy Trial at AAAAI Dynavax Announces Webcast on AAAAI Data and 2007 Financial Outlook Treatment Extends Survival in Mouse Model of Spinal Muscular Atrophy Gamunex Is the Preferred Liquid IGIV Therapy Among Allergists and Immunologists Surveyed Protox Announces PRX302 Data to Be Presented at ASCO Sponsored Prostate Cancer Symposium Positive AS1404 Trial Data Presented at ASCO Prostate Cancer Symposium Cougar Biotechnology Announces Presentation of Positive Phase I and Phase II Data at ASCO Prostate Cancer Symposium

February 26

'Encouraging' Major Responses Seen With Xyotax in Patients With Taxane-Resistant Androgen Independent Prostate Cancer Palatin Technologies and King Pharmaceuticals Announce Presentation Regarding Clinical Study Evaluating Bremelanotide in Post-Menopausal Female Sexual Dysfunction Patients Physicians Still Treating Acute Otitis Media (AOM) as They Did Prior to PCV-7 LifeCycle Pharma Announces Positive Data From LCP-AtorFen Phase I Clinical Program Steroid-Free Astelin Nasal Spray Demonstrated Seasonal Allergy Symptom Improvement Within 15 Minutes in Clinical Study Drug Treatment Improves Learning in Mice With Down Syndrome Symptoms, Stanford/Packard Study Shows Hollis-Eden Pharmaceuticals Reports Publication of Results Demonstrating the Ability of Neumune to Increase Survival in a Primate Model of Lethal Radiation Injury Othera Pharmaceuticals Presents New AMD Data at Angiogenesis 2007 Symposium Phase 3 Stroke Trial Shows That Novoseven Reduces Bleeding in the Brain, but Does Not Improve Long-term Clinical Outcomes Survey Shows Discomfort With Existing Nasal Sprays Causes Allergic Rhinitis Patients to Discontinue Treatment Medivation's MDV3100 Shown to Be Effective in a Preclinical Model of Hormone-Refractory Prostate Cancer Gilead Announces Completion of Phase II Clinical Trial of Novel Investigational HIV Integrase Inhibitor GS 9137 Algeta's Alpharadin significantly improves patient survival in a clinical trial in prostate cancer Avigen's AV411 Highlighted in Special Issue of Neuron Glia Biology New Clinical Data for Prostascint and Quadramet in Prostate Cancer Presented at the 2007 Prostate Cancer Symposium Phase 2 Results of Genasense Plus Chemotherapy in Advanced Prostate Cancer Reported at Cancer Conference LifeCycle Pharma announces positive data from LCP-AtorFen Phase I clinical program

February 27

MAP Pharmaceuticals Reports Positive Phase 2 Results for its Pediatric Asthma Drug Candidate Post-Hoc Data Analyses Published in Annals of Neurology Found Copaxone Significantly Delayed Accumulated Disability in Male Patients with Primary Progressive Multiple Sclerosis (PPMS) Increased Prescription Drug Co-pays Linked to Lower Medication Usage and Higher Hospitalization Rates, Thomson Medstat Study Finds Reported to the American Academy of Allergy, Asthma and Immunology: Pittsburgh Study Suggests Asthma Medication May Provide Relief for the Common Cold MatTek's EpiVaginal Excels in Microbicide/HIV Research Study Podcast Alert: Dr. Eli Meltzer Discusses New Data on Fluticasone Furoate Nasal Spray Studies Showed Fluticasone Furoate Nasal Spray Was Well-Tolerated and Effective in Treating Allergic Rhinitis in Pediatric Patients New Data Showed Fluticasone Furoate Nasal Spray Effectively Treated Nasal Symptoms of Allergic Rhinitis Study Finds C1-Inhibitor Concentrate Is Safe and Effective in Treating Skin Swelling in Patients With Hereditary Angioedema Genitope Corporation to Host Conference Call to Discuss Updated Blinded Data from Its Phase 3 Clinical Trial

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