Clinical Trial News Archive
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August 2011
August 1
August 2
Oncolytics Biotech Inc. Announces Publication of Preclinical Research on Synergistic Combination of Chemotherapy with Oncolytic Virotherapy
Jennerex Reports Positive Mechanistic Proof-of-Concept Clinical Trial Results Using JX-594 to Treat Metastatic Melanoma
Arena and Eisai Announce Completion of Study Measuring Lorcaserin Concentrations in Human Cerebrospinal Fluid and Related Analyses
CytRx's INNO-206 in Combination Therapy Induces Complete Remissions in Aggressively Growing Ovarian Cancer Tumor Model
NIH Awards $84 Million Grant to NYU Langone Medical Center and Partnering Institutions for First-of-Its-Kind Comparative Effectiveness ISCHEMIA Clinical Trial
August 3
Amarantus BioSciences Presents Summary of Peer-Reviewed Data for Parkinson's Program
Actelion's selective S1P1 receptor agonist ponesimod successful in mid-stage trial for multiple sclerosis - Ponesimod to proceed to Phase III final stage of clinical development
Adverse Childhood Could Raise Adult Heart Disease Risk
Use of Antipsychotics for Reducing Military-related Chronic PTSD Symptoms Does Not Appear Effective
August 4
iBio Announces Malaria Vaccine Milestone Achievement on its iBioLaunch Platform
Antares Pharma Announces Positive Study Results with VIBEX MTX in Rheumatoid Arthritis Patients
YM BioSciences JAK Inhibitor CYT387 Shown Active in Multiple Myeloma
Roche?s Investigational Treatment for Asthma Met Its Primary Endpoint in A Phase II Study
PROLOR Biotech Announces Positive Top-Line Results From Phase II Trial of its Long-Acting Human Growth Hormone That Achieved All Key Study Goals
Johnson & Johnson Pharmaceutical Research & Development Scientists Uncover Previously Unknown Role for Class of Molecules
Children's Hospital Los Angeles Researchers Define Key Protein Components Involved in Lung Repair
August 5
Obese Patients Treated With QNEXA Demonstrated Significant Improvement in Quality of Life
A Patient's Own Skin Cells May One Day Treat Multiple Diseases
More Neurology Residents Comfortable Using Stroke Clot-busting Drug
Antares Pharma Announces Positive Study Results With Vibex Mtx in Rheumatoid Arthritis Patients
Oxford BioMedica Announces Interim Data from Highest (5x) Dose Cohort in ProSavin Phase I/II Study in Parkinson's Disease
Molecular Mechanisms Offer Hope for New Pain Treatments
UCLA Study Shows Man-made Fat May Limit Damage to Heart Attack Victims
August 8
August 9
Arena and Eisai Announce Results of Re-Adjudication of Rat Mammary Tumors from Lorcaserin Carcinogenicity Study
Biogen Idec and Abbott Announce Positive Top-Line Results from the First Registrational Trial for Daclizumab HYP in Relapsing-Remitting Multiple Sclerosis
Lilly Announces Review of Data on Long-Term Raloxifene Treatment for Postmenopausal Osteoporosis Published in Current Medical Research & Opinion
Genmab Announces Top-Line Phase Ii Results for Ofatumumab Combined With Chemotherapy in Second Line Aggressive Lymphoma
Phase 2 Trial of Lexicon's LX1032, Telotristat Etiprate, Shows Positive Results in Carcinoid Syndrome
August 10
Omega-3 Fatty Acids Show More Cardiovascular Benefits and May Reduce Risk of Preterm Delivery and Chronic Kidney Disease
Two Gencaro Atrial Fibrillation Abstracts Accepted for Presentation at the American Heart Association Scientific Sessions 2011
Adolor Corporation Announces Positive Results from Phase 2 Program in OIC
August 11
Stroke Prevention in Patients with Atrial Fibrillation: New England Journal of Medicine Publishes Results of ROCKET AF Study of Bayer's rivaroxaban
Lexicon Announces Publication of Results From the Phase 2 Trial of LX1031 in Patients With Irritable Bowel Syndrome in Journal of Gastroenterology
Newly-Published Colchicine Safety Data Provide First Evidence-Based Dosing Guidance to Avoid Potentially Serious Interactions With Commonly Prescribed Drugs
August 12
August 15
Gilead's Investigational Antiretroviral Quad Regimen Meets 48-Week Primary Objective in Pivotal Phase 3 Clinical Study 102
NanoViricides Reports HIVCide Exhibited Long Term Sustained Anti-HIV Effects Even After Drug Discontinuation
Impax and GSK Announce Positive Topline Results of ASCEND-PD Phase III Study of IPX066 in Advanced Parkinson's Disease
Effient (Prasugrel) Showed Significant 26 Percent Reduction in Cardiovascular Events Over Clopidogrel in New Core Clinical Cohort Population Sub-Analysis of the TRITON-TIMI 38 Pivotal Study
Childhood Eye Tumor Made Up of Hybrid Cells with Jumbled Development
August 16
Novel Flavonoid Compounds That Significantly Reduce Cancer Cell Growth Are Available For Further Research and Development as Anti-Cancer Therapeutics
New Study Shows Modified Citrus Pectin Activates Powerful Immune Responses
Clinical Infectious Diseases Publishes Subgroup Analysis Showing Optimer's DIFICID (fidaxomicin) Tablets Exhibited Higher Clinical Cure and Global Cure Rates Than Vancomycin in Patients with Clostridium difficile-Associated Diarrhea (CDAD) Receiving Concomitant Antibiotics
Defect in A20 Gene Expression Causes Rheumatoid Arthritis
NexBio Reports Safety and Significant Antiviral Activities of DAS181 (Fludase)* from a Dose-Ranging Phase II Clinical Trial
Two-Year Follow-Up Data Show Outstanding Clinical Outcomes and Safety for OrbusNeich's Genous Stent in Patients at High Risk for Restenosis
August 17
New Survey Reports Some Postmenopausal Women Endure Vaginal and Sexual Symptoms of Menopause for More Than Two Years before Discussing with Health Care Professional
Journal Republishes the 1996 Landmark Report That Set the Research Strategy for HIV/AIDS
Savient Pharmaceuticals Announces Publication of Pivotal Phase III Krystexxa Data in JAMA Demonstrating Significant Benefits in Refractory Chronic Gout Patients
August 18
AIDS Researchers Isolate New Potent and Broadly Effective Antibodies Against HIV
Clavis Pharma announces encouraging interim results of Phase II trial with elacytarabine in combination with idarubicin in patients with early stage acute myeloid lymphoma (AML)
Basilea reports financial results for the first half-year 2011
Scientists Show how Gene Variant Linked to ADHD Could Operate
HIV Havens: Caltech Researchers Find New Clues about How HIV Reservoirs may Form
Gladstone Scientist Identifies Gene that Exacerbates Risk Factors for Heart Disease and Diabetes
Generex Subsidiary Antigen Express Provides Update on Phase 2 Breast Cancer Immunotherapy Program
August 19
Malaria Parasites Camouflage Themselves from the Immune Defenses of Expectant Mothers
Acne-treating Antibiotic Cuts Catheter Infections in Dialysis Patients
Strengthening Fragile Immune Memories to Fight Chronic Infections
SUNY Downstate Researchers Identify Possible New Targets for Treating Pain in Women
August 22
August 23
Bristol-Myers Squibb And Pfizer Announce Data Presentations For Apixaban At European Society of Cardiology Congress 2011
Aeterna Zentaris to Present Poster on Novel Oral Anticancer Erk Inhibitors at Upcoming American Chemical Society's National Meeting
Bronchodilation in asthmatics maintained with daily dosing of RPL554
Metabolon Study Provides Insight Into Acrolein-Induced Lung Injury
August 24
Prestigious Molecular Biology Journal Publishes Breakthrough Research Led by Dr. Andres Tellez: Milestone Achievement Reflects Robust Brain Trust at Biocodex USA
FREEDOM-C(2) Trial of Oral Treprostinil in Pulmonary Arterial Hypertension Does Not Meet Primary Endpoint
Stay in ICU Means Fewer Patients Likely to Renew Prescriptions After Discharge
TGen and DTU Researchers Track Source of Haitian Cholera Outbreak
Deaths from Strong Prescription Painkillers are on the Increase
Exercise Can Substitute Effectively as Second 'medication' for People with Depression
HIV Experts Create the Roadmap for Providing PrEP to Uninfected Individuals to Reduce the Risk of HIV Infection
NanoBio's Intranasal RSV Vaccine Induces Robust Immunity in Animals
Researchers Find "Key" Used by Ebola Virus to Unlock Cells and Spread Deadly Infection
Obagi Medical Products Announces Publication of Study in the July Edition of the Aesthetic Surgery Journal
August 25
August 26
August 29
Stroke Prevention Therapy Use Low Among High-Risk Patients With Atrial Fibrillation (AF)
ELIQUIS (apixaban) was Superior to Warfarin for the Reduction of Stroke or Systemic Embolism with Significantly Less Major Bleeding in Patients with Atrial Fibrillation in Phase 3 ARISTOTLE Trial
New Data Underscores Importance of Platelet Reactivity Testing to Aid in Risk Assessment
Curemark Reports Positive Results for Novel Compound CM-182 in Amphetamine Induced Hyperactivity
August 30
Aeterna Zentaris Announces Results of its Novel Orally Active Anticancer Erk Inhibitor at the American Chemical Society National Meeting
Results of Phase III Study for Perampanel Presented at 2011 International Epilepsy Congress
Bionovo Announces Positive Results of the Tolerability Trial of Menerba (MF101) for Menopausal Hot Flashes
New Study Demonstrates Effectiveness of Extracorporeal Photopheresis in Early-Stage Cutaneous T-Cell Lymphoma
Actelion reports results of exploratory study with macitentan in IPF patients - promising long-term safety and tolerability profile - efficacy data not supportive of Phase III in IPF
MOLOGEN AG: First evaluation data on clinical trial with MGN1601 ? results for renal cancer therapy considerably better than anticipated
Clearance of Sunshine Biopharma's anti-cancer compound, Adva-27a, does not involve a toxic intermediate
QLT Shows Positive 4 Week Efficacy in Phase II Study for Glaucoma Using Latanoprost Punctal Plug Delivery System
Peregrine Reports Promising 20.7 Month Median Overall Survival From Phase II Advanced Breast Cancer Trial
Safety and tolerability of the oral Xa inhibitor darexaban for secondary prevention after acute coronary syndromes
Zertane Clinical Results Published in the Journal European Urology
August 31
NexBio's DAS181 (Fludase) Improves Symptoms in Four Severely Immunocompromised Patients With Life-Threatening Parainfluenza Pneumonitis
Shire Presents Positive Data from Fabry and Gaucher Disease Studies that Continue to Support Patient Switches to Replagal (agalsidase alfa) and Vpriv (velaglucerase alfa)
Jennerex Publishes Clinical Data in Journal, Nature, Demonstrating Intravenous Delivery of Multi-Mechanistic Cancer-Targeted Oncolytic Poxvirus JX-594 to Tumors
