Clinical Trial News Archive
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News Archive for August 2008
August 1, 2008
- Lux Presents Data at ARVO on LX214 as Potential Treatment for Dry Eye
- Lab Study Shows Methadone Breaks Resistance in Untreatable Forms of Leukemia
- MDRNA, Inc. Demonstrates In Vivo Efficacy with Proprietary DiLA2 Delivery Platform
- Immunotherapy in High-Risk Pediatric Sarcomas Shows Promising Response
- MDRNA Announces Phase 2 Trial of PYY(3-36) Does not Meet Weight Loss Endpoint
- A Long Lasting Impression: New Study Find Persistent Brain Changes in Response to Cocaine Depend on the Expectation of Reward NIDA
- Preclinical Data for a Topical Formulation of Voclosporin as a Potential Best-in-Class Treatment for Chronic Inflammatory Eye Diseases Presented at ARVO
August 4, 2008
- Karo Bio Announces Successful Phase II Study with Eprotirome in Combination with Statin
- Top-Line Results of Boceprevir Phase II Study Showed High Rate of Sustained Response (SVR) in Genotype 1 Treatment-Naive Hepatitis C Patients
- Suven Life Sciences Presents Positive Preclinical Data for SUVN-502 at Alzheimer's Conference, Chicago and Drug Discovery Conference, Boston
- Amicus Therapeutics Announces Successful Completion of End of Phase 2 Meeting With FDA for Amigal in Fabry Disease
- HIV Treatment Widely-Used in Developing Countries May Be Less Effective When Used With Anti-TB Therapy
- Growth Hormone Treatment for HIV-Related Abdominal Obesity Improves Abdominal Fat and Other Cardiovascular Measures, but May Be Limited By Effects on Glucose
- Highly Active Antiretroviral Therapy of Similar Benefit for HIV-Infected Injection Drug Users
- Turned-Off Cannabinoid Receptor Turns on Colorectal Tumor Growth
- New Long-Term Prospective Study of Statin Drugs Confirms Utility To Reduce Risk of Dementia and Memory Loss
- New Research Results Explain How Dormant Tumor Cells Become Active in Later Years
- Leukemia Journal Publishes Results from Darinaparsin Study
- Theratechnologies Reports on Positive Body Image Parameters at the International AIDS Conference
August 5, 2008
- YM BioSciences Reports Phase II Data for Nimotuzumab Metastatic Colorectal Cancer
- Pharmasset Reports Preliminary Results of a 4-week Combination Study of R7128 for the Treatment of Chronic Hepatitis C
- Cara Therapeutics Announces Successful Completion of Phase I Clinical Trial of Novel Analgesic, CR845
- Xanodyne Achieves Positive Efficacy Results in Pivotal Phase 3 Studies of Proprietary Modified Release Oral Tranexamic Acid Product Candidate for Heavy Menstrual Bleeding
- Rib-X Pharmaceuticals, Inc. Announces Recent and Upcoming Presentations at Scientific Conferences
- Orthokine Treatment is Effective for Knee Arthritis, Even After Two Years
- Urologists Should Recognize the Cardiac Safety of Prescribed Medications, Article Concludes
- Treatment With Anti-Anemia Drugs May Not Be Safe For Multiple Myeloma Patients
- MIV Announces Excellent Safety and Efficacy of VESTAsync Polymer-Free Drug-Eluting Stent at 12-Month Clinical Follow Up
- YM Biosciences Conference Call to Discuss Phase II Data for Nimotuzumab in Metastic Colorectal Cancer
- CASTLE Data Showed Boosted Reyataz (atazanavir sulfate) and Lopinavir/r Achieved Similar Results for Undetectable Viral Load in Treatment-Naive HIV-1 Infected Patients, Regardless of Gender
- Ninety-Six Week Data on Tibotec Investigational NNRTI, TMC278, Presented at AIDS 2008
- Isentress (raltegravir), Merck's First in Class Integrase Inhibitor, Reduced HIV Viral Load and Increased CD4 Cell Counts Through 96 Weeks in Treatment-Naive HIV-Infected Patients When Taken With Other Anti-HIV Medicines
- Abbott's Kaletra Tablet Dosed Once-Daily or Twice-Daily Demonstrated Similar Clinical Results Across Race and Gender Lines
- Stanford Study Finds HIV Drug Can Persist in Mothers' Milk, Increasing Risk to Them and Their Babies
August 6, 2008
- CASTLE Data Showed Boosted Reyataz (atazanavir sulfate) and Lopinavir/r Achieved Similar Results for Undetectable Viral Load in Treatment-Naive HIV-1 Infected Patients, Regardless of Gender
- Dynavax and Merck & Co., Inc. Announce Phase 3 Trial with Investigational Hepatitis B Vaccine (HEPLISAV) Met its Primary Endpoint
- Isolagen, Inc. Reports Positive Top-line Results from Pivotal Phase III Studies of Isolagen Therapy(TM) in Wrinkles: Studies Meet All Primary Efficacy Endpoints and are Statistically Significant
- Inspire Announces Peer-Reviewed Publications Related to Denufosol for Cystic Fibrosis
- Protherics Plc DEEP Results in Pre-Eclampsia to be Presented at Leading Conference
- Cortex's AMPAKINE Molecule CX717 Has Positive Effects in Opiate-Induced Respiratory Depression in a Phase IIa Clinical Study
- Mesoblast Limited (ASX:MSB); Non-healing Bones Repaired II Clinical Trial Using Adult Stem Cells
- Oramed Pharmaceuticals Announces Successful Phase 2A Clinical Trial of its Oral Insulin Capsule
- Pooled-Analysis of 54 Clinical Studies Shows No Increased Risk of Heart Attack With Abacavir Therapy
- Genetic Biomarker Linked to Subcutaneous Growth Hormone Dose-Response
- Lipitor 80 mg Reduced the Risk of Heart Attack and Stroke in Patients with Heart Disease, Type 2 Diabetes and Chronic Kidney Disease
August 7, 2008
- Ondine Announces Publication of Positive Results from Pseudomonas aeruginosa Eradication Study
- Nature Publication Reports on Key Role of Bile Acids in Glucose Metabolism and Insulin Signaling
- New Survey Explores the Impact of Insulin Injections and Communications Between Patients and Healthcare Providers
- New Prostate Cancer Test is Ready for Commercialization Following Successful Completion of Final Clinical Trials
- Argos Therapeutics' Arcelis Personalized Immunotherapy Platform in HIV Achieves Primary Endpoint in Phase 1 Trial
- Mesoblast Limited (ASX:MSB) National Media Coverage Focused on Results of Adult Stem Cell Bone Repair Trial
- IMPAX Reports Positive Results in Phase III Trial with IPX056
- Head-to-Head 96-Week Study Shows Epizcom is Comparable to Truvada in Efficacy and Safety Measures in HIV Treatment-Naive Patients
- Analysis of Six Clinical Trials Finds Epzicom Effective in Treatment-Naive HIV Patients With Both High and Low Baseline Viral Loads
- Ardea Biosciences Presents Phase 2a Antiviral Activity Data for Lead HIV Candidate, RDEA806 at XVII International AIDS Conference
- Macular Degeneration Risk Studied in an Asian Population; Time Spent Outdoors Impacts Nearsightedness in Children; and Two Treatments to Combat Ocular Surface Cancer
August 8, 2008
- Abbott Study Shows Investigational Heat-Stable Norvir(R) Tablet Provides Similar Drug Levels to Current Norvir Capsule
- Santhera Provides Update on Clinical/Regulatory Processes with SNT-MC17/Idebenone for the Treatment of Friedreich's Ataxia
August 11, 2008
- NanoViricides, Inc. Reports that HIVCide-I Was Significantly Superior to the Current Anti-HIV Three Drug Cocktail Standard
- Altus Pharmaceuticals Announces Achievement of Primary Endpoint in Phase 3 Efficacy Trial of Trizytek for Cystic Fibrosis Patients with Pancreatic Insufficiency
August 12, 2008
- Alnylam and Collaborators Publish New Preclinical Research on RNAi-Mediated Silencing of PCSK9
- Losing Weight After Diabetes Diagnosis can Prevent Diabetes-Related Disease, Kaiser Permanente Study Finds
- Dicerna Pharmaceuticals' Co-founders Publish Studies Describing Novel Approaches to Maximizing Dicer-Substrate Small Interfering RNAs (DsiRNAs)
- Javelin Presents PMI-150 (Intranasal Ketamine) Data at Premier Department of Defense Scientific Meeting
- VitiGam Inhibits Melanoma Growth in a Dose Dependent Manner
- Bronchitol Cystic Fibrosis Dose Trial Results Positive
- Canopus Biopharma and Leading Chinese Researcher Team Up to Treat Avian Influenza, to Prevent Possible Pandemic
- Mesoblast Limited Stem Cells Regrow Knee Cartilage in Severe Post-Menopausal Osteoarthritis
- Cholesterol Drug Plays Role in Melanoma Remission
- Experimental Chemotherapy Regimen Shows Promise in Treating Advanced Lung Cancer
- Risk Assessment Plays Key Role in Long-Term Treatment of Breast Cancer
August 13, 2008
- NewCardio Announces Positive Results From Third Clinical Validation Study
- MDRNA, Inc. Lead Candidate Demonstrates In Vivo Efficacy against Seasonal and Pandemic Flu Strains
- Nasal Hepatitis B Vaccine Elicits Robust Immunity With a Single Dose; Confers Major Advantages Over Traditional Vaccines
- Obesity, Previous Use of HRT, and Treatment with Aromatase Inhibitors Puts Postmenopausal Women with Early-Stage Breast Cancer at Increased Risk of Joint Symptoms
- NIH Scientists Find a Novel Mechanism that Controls the Development of Autoimmunity
- i3 Drug Safety to Deliver 17 Presentations at ICPE 2008
August 14, 2008
- Palatin Technologies, Inc. Reports Positive Results of Phase 2a Clinical Study with PL-3994 for the Treatment of Heart Failure
- Nuvelo Announces Positive Phase 1b Proof-of-Concept Data With Anticoagulant NU172
- Nuvelo Announces Positive Phase 1b Proof-of-Concept Data With Anticoagulant NU172
- Probiodrug to Present Potential New Treatment for Alzheimer’s Disease
- New Study Highlights Importance for Women to Know Their Risk of Heart Disease
- Nutra Pharma Announces Initial Positive Safety Data from Clinical Study in Adrenomyeloneuropathy (AMN)
- 'Protein Complementarity' May Offer New Insights Into Autoimmune Diseases
- Micromet Data Show Tumor Regressions in Relapsed Lymphoma Patients Treated with T Cell Engaging BiTE Antibody Blinatumomab
- Researchers Find Leishmaniasis Parasites Evade Death by Exploiting the Immune Response to Sand Fly Bites
August 15, 2008
- Antisoma plc: Evidence of Activity Seen in New Data from ASA404 Prostate Cancer Trial
- Alternative Vaccine Strategy Shows Promise in Prostate Cancer Patients
- Treatment with Plerixafor Shown to Improve Mobilization of Cells in Donors During Bone Marrow Stem Cell Collection Procedures
- Giving Heart Attack Patients Anticlotting Drug Tirofiban in Ambulance Improves Clinical Outcome in Hospital (On-TIME 2 Study)
- Combination Therapy Reduces Proteinuria More Than Single Drugs but causes More Kidney Damage (ONTARGET STUDY)
August 18, 2008
- Repros Therapeutics Inc. Provides Update for US Phase II Endometriosis Study and Completion of QT Interval Dose Selection Screen
- Micromet, Inc. to Host Webcast and Conference Call to Discuss Blinatumomab Data Published in SCIENCE
- Dyax Announces DX-88 for Hereditary Angioedema Meets Primary and Secondary Endpoints in Phase 3 Trial (EDEMA4(R))
- Logical Therapeutics Inc. Announces Results of Phase 1b Clinical Study of its Naproxen Prodrug
- Prescription Sleeping Pill Use Tied to Cancer
- Use of Conventional Antipsychotics Medications Linked to Increased Risk of Cardiovascular, Respiratory Disease Deaths in Elderly Patients
August 19, 2008
- Regeneron and Bayer HealthCare Announce VEGF Trap-Eye Achieved Durable Improvement in Vision over 52 Weeks in a Phase 2 Study in Patients with Age-Related Macular Degeneration
- Afid Therapeutics Inc.'s New Anticoagulant Heparin Replacement Passes in Vivo Test
- Pain Therapeutics and King Pharmaceuticals Announce Final Data of Remoxy Phase III Study at World Pain Congress in Scotland
- Regulus Therapeutics and Collaborators Publish New Data on a Critical Role for miR-21 in Brain Tumors
- Journal of Cardiovascular Electrophysiology Publishes Data Showing Ranolazine Shortened QT Interval and Improved Cardiac Relaxation in Study of Patients With Long QT Syndrome
- New Data Show Prolonged Release Oxycodone/Naloxone Provides Effective Pain Relief and Reduces OIC in Patients with Severe Chronic Pain
- Hayes Evaluates Test and Treatment Options for Attention-Deficit Hyperactivity Disorder
- Bacterial Pneumonia Caused Most Deaths in 1918 Influenza Pandemic Implications for Future Pandemic Planning
- Viral Genetics, Inc. Unveils Potential Mechanism of Action in HIV/AIDS Research, Accepted to Present Findings at Prestigious IHV Meeting
- Clinical-Scale Generation of Functional Red Blood Cells from Human Embryonic Stem Cells
August 20, 2008
- 12 Month Phase 3 Trial Finds Bronchitol Safe in Bronchiectasis
- Positive Findings Published on Emergent Technology for Treating Chronic Pain
- TheraQuest Presents Topical Local Anesthetic and Abuse Deterrence Data at the World Congress on Pain
August 21, 2008
- Vaxfectin-formulated Measles DNA Vaccine Could Address Unmet Need for Infants
- Repros Therapeutics Inc. Announces No Tumors in First Completed Proellex Animal Carcinogenicity Study
- PTC124 Shows Promising Activity in Cystic Fibrosis; Phase 2 Proof-of-Concept Data Published in the Lancet
- Metvix Prevents Pre-cancerous Lesions in Transplant Patients
- Head-to-Head Study Showed Prasugrel Statistically Superior to Clopidogrel in Reducing Recurrent Cardiovascular Events
- Novavax to Present Phase I/IIa Trial Data Results in an Investor Conference Call on August 26, 2008
- Catalyst Pharmaceutical Partners Announces Publication of Animal Data Demonstrating Vigabatrin Effective for Weight Loss
- Javelin Presents Successful Pivotal Phase 3 Secondary Clinical Results for Dyloject at the 12th World Congress on Pain
- Kamada Successfully Completes Phase II Trial with Aerosolized AAT in Cystic Fibrosis Patients
- VaxInnate's M2e Universal Influenza Vaccine Candidate Demonstrates Safety and Immunogenicity in Phase I Clinical Study
- New Drug for Cystic Fibrosis Bypasses Genetic Defect and Improves Cell Membrane Function
August 22, 2008
- ARYx Therapeutics, Inc. Announces Successful Results of Chronic Constipation Clinical Trial on ATI-7505
- Telik's Proteasome Inhibitor Program Meets a Preclinical Development Milestone
- Synta Announces Publication of Elesclomol Mechanism of Action Results in AACR Journal Molecular Cancer Therapeutics
- Mesoblast Limited's (ASX:MSB) Allogeneic, "Off-The-Shelf", Stem Cells Are Safe And Effective For Cervical Spine Fusion
August 25, 2008
- Patients Taking Cymbalta Experienced Reduced Chronic Low Back Pain in New Study
- Extensively Drug-resistant Tuberculosis Can be Managed with Aggressive Treatment Strategy
- NicOx Provides Update on PF-03187207 and the Ongoing Research Collaboration with Pfizer
- Isolagen Reports Positive Results from Open Label, Phase II Study of Isolagen Therapy of the Full Face Regarding the Treatment of Wrinkles and Skin Quality Characteristics
- Role of pramipexole in key research areas of Parkinson’s disease management discussed at 12th EFNS Congress
August 26, 2008
- ADAGIO Trial Results Show Teva's Azilect 1 mg Tablets Slow Progression of Parkinson's Disease
- More Evidence Published That Epidemics of Childhood Obesity, Type 2 Diabetes and Metabolic Syndrome are Linked to Immunization
- Infections Linked to Premature Births More Common Than Thought, Stanford Study Finds
- NeuroDiscovery Ltd: NSL-101 Demonstrates Effective Pain Relief in Phase IIa Trial
- Pharmalink Reports Positive Phase III Results for Xepol, a Treatment for Post-Polio Syndrome
- Novavax Announces Favorable Results from Phase I/IIa Pandemic Influenza Vaccine Program
- XTENT Announces CUSTOM II Data Selected for Publication in EuroIntervention
- Omeros Announces Publication of Clinical Results for OMS103HP in Arthroscopy: The Journal of Arthroscopic and Related Surgery
- Pramipexole Clinical Trial Programme in Restless Legs Syndrome (RLS) Reveals New Significant Results
- New Publication Shows Cleviprex is Safe and Effective for Treatment of Acute, Severe Hypertension
- Professor John F. Thompson to Present at Perspectives in Melanoma XII, Thursday October 2, 2008
- Early Trigger for Type-1 Diabetes Found in Mice, Stanford Scientists Report
- ACUITY 1-Year Sub-Analysis Published in Journal of the American College of Cardiology
- SF1126, Semafore's PI3 Kinase Inhibitor, Found to Block Angiogenic Signaling From Both VEGF and Bv8 in Multiple Cell Lines
- Individuals With History of Nonmelanoma Skin Cancer at Greater Risk for Future Cancers
August 27, 2008
- Bristol-Myers Squibb and Pfizer Provide Update on Apixaban Clinical Development Program
- Ark’s Vitor commences patient enrolment into Phase III pilot study
- Semafore Broadens Pipeline With Multi-Targeted Kinase Inhibitors
- Photocure Announces Positive Phase II Results with Visonac for Acne
- Curis Announces Nature Publication Elucidating a Paracrine Mechanism of Action in Hedgehog-Expressing Tumors
- Stallergenes: New Study VO 56 Highly Positive Results Conducted in an Allergen Challenge Chamber
August 28, 2008
- Algeta Reports Positive Headline Phase II Data on Pain Palliation With Alpharadin
- The University of Nottingham in the British Midlands Announces Breakthrough in Parkinson's Disease Research
- National Study Shows Magnesium Sulfate Reduces Risk of Cerebral Palsy in Premature Births
- New England Journal of Medicine Publishes Phase III Results of Velcade (Bortezomib) for Injection in Previously Untreated Multiple Myeloma Patients
- ThermoDox Liver Cancer Study Phase I Results to Be Presented at ILCA Conference 2008
- The Cypher Sirolimus-eluting Coronary Stent Outperforms the Taxus Stent in People with Diabetes
- Alseres Pharmaceuticals Announces Preclinical Study Results Demonstrating that Rho Inhibitors Could Be Useful in Promoting Bone Healing
- Academic Publication Highlights Method for Stabilizing the Adenosine A2a G-protein Coupled Receptor for Drug Discovery Studies
- Low Levels of Brain Chemical May Lead to Obesity, NIH Study of Rare Disorder Shows
- Oral Tolerability of Cysteine-Rich Protein Isolate (Immunocal) in Autism - A Pilot Study
