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April 2007

April 2

Data on Telavancin and Micafungin Hold Promise of New Therapeutic Options in Fight Against Serious Infectious Disease Helix BioPharma Corp. Announces Positive Phase II Clinical Results with its Topical Interferon Alpha-2b Six Important Things to Know About Preventing Hospital Infections Trichomoniasis: Most Common Curable STD in U.S. Affects 7.4 Million Annually NeoPharm Provides Update on LE-SN38 Program Immunosuppressant Drug Prevents Tobacco Induced Lung Cancer in Mice Large Study Shows that Presence of Neutralizing Antibodies Did Not Predict Clinical Response to Betaseron Treatment M. D. Anderson Cancer Center Researchers to Present CTCE-9908 Data at the AACR Annual Meeting Novavax Vaccine Provides Robust Immune Response, Pre-Clinical Data Show State of Diabetes in Pittsburgh: Pittsburgh Business Group on Health Releases Report NIDA Study Identifies Genes That Might Help Some People Abstain from Smoking Researchers Discover a Common Variation in a Gene Segment that Increases the Risk for Prostate Cancer

April 3

Arrowhead Subsidiary Calando Pharmaceuticals Publishes Study Showing Anti-Cancer Effect with Lead RNAi Candidate Calando Pharmaceuticals Publishes Study Showing Anti-Cancer Effect with Lead RNAi Candidate Cell Genesys Provides Final Median Survival Data From Second Phase 2 Trial of GVAX Immunotherapy for Prostate Cancer Opexa Therapeutics Reports Positive Top-line Data in Phase I/II Dose Escalation Trial with Tovaxin for Multiple Sclerosis Repros' Proellex Shows Statistically Significant Improvement in Primary Endpoint in Phase 2 Trial in the Treatment of Uterine Fibroids Latest NIMH Study on Bipolar Disorder Once Daily, Extended-Release Ropinirole Improves Parkinson's Symptoms in Patients not Optimally Controlled With Levodopa Pharmasset Announces Clevudine and Hepatitis C Presentations at EASL New Data Show Early Non-Response to Antipsychotic Treatment May Be Strong Predictor of Subsequent Non-Response for People with Schizophrenia PharmAthene's Recombinant Butyrylcholinesterase (rBChE) Program the Subject of Promising New Alzheimer's Research Targanta Reports Improved Ability of Oritavancin to Stop Bacteria Growth In Vitro Compared With Other Glycopeptide Antibiotics New Data Confirm That Use of Levemir Can Limit Weight Gain Southern Research Institute to Present at the 2007 American Association For Cancer Research Annual Meeting Allon Therapeutics to Present New Data at Leerink Swann Alzheimer's Conference Rapid Response was Crucial to Containing the 1918 Flu Pandemic Pharmathene's Recombinant Butyrylcholinesterase (rBChE) Program the Subject of Promising New Alzheimer's Research Scientific Results Presented At ECCMID Demonstrate Well- Differentiated Profile of Basilea's Two Phase III Anti- infective Compounds

April 4

CytoGenix Announces Successful Testing of synDNA Vaccine for Avian Influenza Virus Novagali Pharma Announces Positive Vekacia Clinical Results From Pivotal Phase III Trial in Vernal Keratoconjunctivitis ECOG Phase III Newly Diagnosed Multiple Myeloma Trial (E4A03) Reports Lenalidomide Plus Low-Dose Dexamethasone Suggests Survival Advantage for Patients with Multiple Myeloma Survival Data Available From Erbitux Study in First-Line Treatment of Advanced Head and Neck Cancer Icagen Terminates Phase III ASSERT Study New Analysis of Data from WHI Provides Reassurance With Respect to Coronary Heart Disease For Newly Menopausal Women Considering Hormone Therapy Portola Pharmaceuticals Announces Positive Phase II Results for PRT054021 for Prevention of Venous Thromboembolism Following Total Knee Replacement Surgery CytRx Announces Positive Results of Arimoclomol in Preclinical Stroke Recovery Studies Eurand Announces Positive Phase III Clinical Study Results Nuvelo Announces Presentation on NU206 at 2007 American Association for Cancer Research Annual Meeting SuperGen to Highlight Oncology Pipeline Data in Multiple Presentations at AACR Trexima (Sumatriptan/Naproxen Sodium) Superior Efficacy Data Published in JAMA ARIUS to Present at American Association for Cancer Research Annual Meeting CytImmune To Present At ASCO Phase I Clinical Trial of CYT-6091 to be Presented on June 3, 2007 Over 10,000 UK Breast Cancer Patients Could Become Eligible Within the Next Year for a Breast Cancer Therapy Showing Increased Survival Rates, Reveals Synovate Healthcare’s European Oncology Monitor

April 10

GSK and Adolor Announce Preliminary Results from Phase 3 Safety Study of Alvimopan (Entereg/Entrareg) Nasulin Interim Results to Be Presented at American Diabetes Association Scientific Sessions Kosan Announces Data Presentations at Upcoming AACR Annual Meeting Inotek Pharmaceuticals Announces Publication of Animal Data from Study of PARP Inhibition as Potential Preventative of Brain Injury Following Stroke Data Available from Erbitux Phase III Study in First-Line Treatment of Advanced Pancreatic Cancer Infinity and MedImmune to Present Preclinical Data From Study of Oral Formulation of IPI-504 At AACR First-of-its-Kind National Report Reveals Estimated High Prevalence and Heavy Cost of Type 2 Diabetes Complications in America Pharmacopeia Announces Positive Results from Initial DARA Clinical Trial Avalon Pharmaceuticals to Present at the American Association for Cancer Research 2007 Annual Meeting Telik Announces Telcyta Clinical and Preclinical Presentations at AACR Meeting Scientists Implicate Gene in Vitiligo and Other Autoimmune Diseases Study Shows Children With ADHD Who Start on Strattera are More Likely to Change Therapies

April 11

InterMune Presents Research on ITMN-191 in Hepatitis C at EASL Annual Meeting Pharmacyclics Announces Presentations on Its Novel and Selective HDAC and Bruton's Tyrosine Kinase Inhibitor Compounds Rigel Provides Clinical Update of R788 Phase 2 Trials in ITP, Rheumatoid Arthritis and Lymphoma Vertex Pharmaceuticals Announces New Data for Investigational HCV Protease Inhibitor Telaprevir to be Presented at 42nd Annual Meeting of the European Association for the Study of the Liver (EASL) First Pharmacoeconomic Analysis with Long-Term Data Showed Copaxone Was More Cost-Effective Than Interferon Beta Therapies for Treatment of Relapsing-Remitting Multiple Sclerosis (RRMS) New Clinical Study Results Indicate Higher Early Virologic Response with Celgosivir Combination Therapy in HCV Non-Responders Cyclacel Pharmaceuticals to Present Preclinical Data on Sapacitabine and Seliciclib at AACR Schering-Plough Addresses Major Milestones and Challenges in Treatment of Patients With Chronic Hepatitis C Callisto Pharmaceuticals Announces Publication of Research Article on Atiprimod Preclinical Studies in Mantle Cell Lymphoma Gloucester Pharmaceuticals Announces Multiple Presentations of Preclinical Romidepsin Data at American Association of Cancer Research Annual Meeting Vical's Vaxfectin Adjuvant Achieves Dose-Sparing Effect With Seasonal Influenza Vaccine Nuvelo Announces Publication of NU206 Study Results in Gastroenterology Newest Adult Stem Therapy Treats Diabetes Fragile X, Down Syndromes Linked to Faulty Brain Communication, Stanford Researcher Finds Innovive Pharmaceuticals Announces Data from Oncology Drug Programs to be Presented at American Association for Cancer Research Annual Meeting Valeant Pharmaceuticals Announces Publication of Retigabine Phase 2 Study Data in Neurology

April 12

DNA Therapeutics Reports a Novel Mechanism of Action and a Biomarker of its Lead Molecule Dbait That Open an Innovative Pathway-Targeting in Molecular Cancer Therapy Idenix Reports Results from Two Phase IIb Studies of the Combination of Valopicitabine and Pegylated Interferon in Hepatitis C Genotype-1 Patients at the 42nd Annual Meeting of the European Association for the Study of the Liver Innovive Pharmaceuticals Announces Additional Data Presentations at American Association for Cancer Research Annual Meeting Affymax Announces Results From Phase 2 Clinical Trial of Hematide for the Treatment of Anemia in Dialysis Patients CuraGen Announces New Preclinical Results with Belinostat and Velafermin to be Presented at AACR Annual Meeting Intarcia Therapeutics Announces Final Results From a Phase 2 Study of Injectable Omega Interferon plus Ribavirin for the Treatment of Hepatitis C Genotype-1 Advanced Magnetics Announces Positive Results from Two Additional Phase III Studies of Ferumoxytol as an Intravenous Iron Replacement Therapeutic AVEO Pharmaceuticals Novel Oncology Research Platform and Clinical Pipeline to Be Featured at AACR Liponex Inc. Reports Further Analysis of CRD5 Phase I/II Clinical Trial Data Hana Biosciences Announces Data to be Presented On Talvesta (Talotrexin) for Injection at The American Association for Cancer Research Annual Meeting Costs of Eradicating Poliomyelitis Now Are Much Lower Than Trying to Control It Later

April 13

ANA380 Exhibits Activity In Vitro Against Multiple Clinically Relevant Hepatitis B Virus Mutants Enzon to Present Preclinical Data From PEG-SN38 and PEGylation Technology Studies at AACR Meeting Data Analyses Outline Efficacy and Safety of Mircera for the Treatment of Renal Anemia Associated With Chronic Kidney Disease Baraclude (entecavir) Therapy Resulted in Undetectable Levels of Hepatitis B Virus in Cohort of Patients Who Re-Started Treatment Ascenta Therapeutics Highlights Multiple Data Presentations at Upcoming AACR Annual Meeting Sunesis Pharmaceuticals to Present Data at the Annual Meeting of the American Association for Cancer Research Gentium's Defibrotide Highlighted in Two Poster Presentations at American Association for Cancer Research Annual Meeting Point Therapeutics Announces Preclinical Data Presentations at Upcoming American Association of Cancer Research Annual Meeting Immunicon Will Exhibit CellCapture CTC Mouse/Rat Kit and EasyCount System for Automated Cell Counting at AACR Positive Results Prompt US National Cancer Institute to Make Gleevec Available To Patients in Post-Surgical Gist Study Positive Results Prompt US National Cancer Institute to Make Glivec Available to Patients in Post-Surgical GIST Study Abbott Researchers Focus on New Cutting-Edge Approaches in the Fight Against Cancer ViroPharma Announces Presentation of Additional HCV-796 Data at Meeting of The European Association for the Study of the Liver AEterna Zentaris To Present First In Vitro Data for PI3K Inhibitors and In Vivo Results for a GHRH Antagonist at the AACR Annual Meeting in Los Angeles Mersana Therapeutics, Inc. to Present Preclinical Data on XMT-1001 at American Association of Cancer Research Annual Meeting New One-Year Pharmacoeconomic Study Shows Avonex is Cost-Effective Relative to Other Interferon Therapies for Multiple Sclerosis CombinatoRx to Present Combination High Throughput Screening (cHTS) Data at Upcoming AACR Meeting DX-88 for Hereditary Angioedema Meets Primary and Secondary Endpoints in Phase 3 Trial (EDEMA3) Cequent Pharmaceuticals Founder to Present tkRNAi Technology at the American Association of Cancer Research Annual Meeting in Los Angeles Vion Presents Data on Cloretazine (VNP40101M) at the 100th Annual Meeting of the American Association of Cancer Research (AACR) UCLA: Lithium Builds Gray Matter in Bipolar Brains, UCLA Study Shows

April 16

Rigel to Present New Research Programs at AACR Meeting AEterna Zentaris Discloses First In Vitro Data for its PI3K Inhibitors at the AACR Annual Meeting in Los Angeles ZIOPHARM Presents Unique Mechanism Data for Indibulin at AACR Poster on Cyclosert Drug Delivery Presented at AACR Meeting Access Pharmaceuticals Announces Poster Presentations on ProLindac at the American Association for Cancer Research 2007 Annual Meeting Novelos Therapeutics and MUSC Present Two Posters at AACR 2007 Annual Meeting Interim Results Presented at EASL from PROVE 1 Clinical Trial of Investigational Drug Telaprevir in Patients with Genotype 1 Hepatitis C Data from Investigator-Sponsored Trial of Oncophage Cancer Vaccine in Glioma Presented at American Association of Neurological Surgeons Annual Meeting Ceregene Presents Long Term Follow-Up Data From Phase 1 Trial of CERE-120 Demonstrating Improved Motor Function in Parkinson's Patients AVAX Technologies Presents Results of Phase I-II M-Vax Trial at Annual Meeting of American Association for Cancer Research Sunesis Presents Data Supporting SNS-032's Potential Anticancer Activity in Multiple Myeloma at the American Association for Cancer Research Meeting Data supporting three Antisoma programmes presented at AACR Genzyme Announces Successful Completion of Study Investigating Sevelamer Carbonate in Patients With Chronic Kidney Disease Data Presented at AACR Meeting Shows Peregrine's Selective Anti-VEGF Antibodies are as Effective as Avastin(R) in Preclinical Cancer Models Boston Life Sciences, Inc. Announces Presentation of Cethrin Phase I/IIa 6-Month Results at 75th Annual Meeting of the American Association of Neurological Surgeons ZIOPHARM Presents Data on Orally Active ZIO-201 at AACR Somanta Announces the Presentation of Alchemix Data at The American Association for Cancer Research Annual Meeting Expression Genetics, Inc. Announces Successful Completion of Phase I Trial of Gene-Based IL-12 for Treatment of Ovarian Cancer Preclinical Data Show Alfacell's Onconase Inhibits Tumor Growth of Non-Small Cell Lung Cancer, Breast Cancer Cells Threshold Pharmaceuticals Announces Multiple Presentations on Oncology Pipeline at the 2007 American Association for Cancer Research (AACR) Annual Meeting Sirion Therapeutics Receives Orphan Drug Designation for Ophthalmic Drug to Treat Viral Eye Infection Achillion Presents Positive Data on Novel Mechanism for Treating HCV at EASL Annual Meeting Aranesp Phase 3 Study in Patients with Active Cancer Not Receiving Concurrent Chemotherapy or Radiotherapy Presented at AACR Annual Meeting Randomized Phase III Trial Showed Erbitux Significantly Improved Secondary Endpoints of Progression-Free Survival and Disease Control in Metastatic Colorectal Cancer Patients Biomira Selects PX-866 as Clinical Development Candidate and Presents Promising Preclinical Data at AACR Onconova Therapeutics Announces Presentation of Clinical and Non-Clinical Results for Its Lead Compound ON 01910.Na at American Association of Cancer Research Conference in Los Angeles Bionovo to Present Recent Findings of BZL101, Its Anti-cancer Agent, at the American Association of Cancer Research Introgen Presents ADVEXIN Biomarker Data at Major Cancer Conference Calando Pharmaceuticals Announces Preclinical Efficacy and Safety Data of Targeted, Systemic Delivery of siRNA at AACR Annual Meeting EntreMed Presents Multi-Mechanism Antitumor Data for ENMD-1420 in Preclinical Models Arrowhead Subsidiaries Insert & Calando Present Data on Cyclosert Drug Delivery System at AACR Meeting Progen's Phase 2 Liver Cancer Trial Exceeds Efficacy Objective Kosan Presents Preclinical Antitumor and Safety Data On Next-Generation Epothilone KOS-1803 at AACR Kosan Presents Data on Cardiac Safety Profile of Hsp90 Inhibitor Tanespimycin (KOS-953) at AACR Karmanos Physician-Scientists Examine Racial Disparities in Patients with Gynecologic Cancer Research Supported by Samuel Waxman Cancer Research Foundation Discovers Mode of Action of Arsenic-Based Drugs in Destroying Cancer Cells

April 17

AEterna Zentaris Discloses In Vivo Data for its GHRH Antagonist JMR-132 at the AACR Annual Meeting in Los Angeles Cell Genesys Reports GVAX Immunotherapy for Prostate Cancer Induces a Broad, Patient-Specific Antibody Response EntreMed Presents Multi-Mechanism Results for ENMD-1198 at AACR Annual Meeting GTx Announces Ostarine Improved Insulin Resistance among Elderly Patients in a Recently Completed Phase II Clinical Trial Telik Reports Positive Data Demonstrating Synergy in Combination and Highly Statistically Significant Effect of Telcyta as Maintenance Therapy in First-Line Non-Small Cell Lung Cancer Addex Achieves Statistically Significant Outcome in Phase IIa Clinical Trial With ADX10059 in Gastro-Esophageal Reflux Disease GenVec Announces New Research at AACR on Selectivity and Mechanism of Action of TNF-Based Anti-Cancer Therapy ProNAi Announces Preclinical Success for PNT2258 Therapeutic - Curative Events in Xenograft Mice for Difficult-to-Treat Non-Hodgkin's Lymphoma Curis Announces Hedgehog and Wnt Antagonist Data Presentation at AACR ArteFill 5-Year Data to Be Presented at American Society for Aesthetic Plastic Surgery Annual Meeting Medarex Presents Preclinical Data Demonstrating Potent Anti-Tumor Activity of Anti-CD19 and Anti-CD70 Antibody-Drug Conjugates in Cancer Animal Models Data Published in Neurology Showed That Higher Dose of Copaxone Increased Efficacy in Relapsing-Remitting Multiple Sclerosis (RRMS) Millennium Discovers Biomarkers Potentially Predictive of Response to Velcade (Bortezomib) for Injection AVEO Presents Preclinical Efficacy Data on AV-412, a Novel Oral Tyrosine Kinase Inhibitor of EGFR/HER2 for EGFR Mutant and Drug-Resistant Lung Cancer Oncolytics Biotech Inc. Research Collaborators Demonstrate Reovirus/Gemcitabine Combination Has Synergistic Effect Against Human Colon Cancer Cell Lines Lorus Therapeutics Announces Scientific Presentations for Lead Antisense and siRNA Drug Candidates at International Cancer Conference OncoGenex Technologies Announces Phase II Data of OGX-011 in Metastatic Breast Cancer at American Association for Cancer Research 2007 Annual Meeting Anadys Reports Preclinical Data Showing ANA773 Promotes Anti-Tumor Activity of Natural Killer Cells Data Presented at AACR Meeting Shows Bavituximab Equivalent Plus Docetaxel Reduces Growth of Both Hormone-Dependent and Hormone-Independent Prostate Cancer by Up to 94 Percent in Preclinical Studies Alzheimer's Drug Shows Promise in Fighting Cancer Cougar Biotechnology Presents Positive CB7630 Clinical Data at AACR Annual Meeting Late-Breaking Clinical Trials Session Alnylam Announces Advancement of a New RNAi Therapeutic Development Program for the Treatment of Liver Cancer Cervarix, GSK Cervical Cancer Candidate Vaccine, Demonstrates 100 Percent Protection Against Precancerous Lesions Caused By Cancer-Causing Human Papillomavirus Types 16 & 18 for More Than Five Years ZIOPHARM Presents Data Highlighting Oral ZIO-101 at AACR Æterna Zentaris Discloses First In Vitro Data for its PI3K Inhibitors at the AACR Annual Meeting in Los Angeles Data on Higher Dose of Copaxone and Data Showing Copaxone is Most Cost Effective Adnexus Therapeutics Announces Presentation at the American Association for Cancer Research (AACR) on Clinical Product Candidate, CT-322 Myriad Genetics Presents Azixa's Mode of Action at AACR

April 18

Pharmacyclics Identifies Functional Biomarkers for its Novel HDAC Inhibitor and Demonstrates Preclinical Anti-Tumor Activity with Bruton's Tyrosine Kinase Inhibitors Avanir Pharmaceuticals Announces Positive Results of Phase III Study for Zenvia in Diabetic Neuropathic Pain Gemin X Presents Positive Preclinical Data of GX15-070 in Infant ALL at AACR Meeting Onconase has Potential as Chemopreventive Agent in Mesothelioma, Reports World-Renowned Mesothelioma Researcher at AACR Annual Meeting Idera Pharmaceuticals Announces Presentations of Preclinical Data on New Potential Oncology Applications of its TLR9 Agonists at AACR Data Presented at AACR Meeting Show Peregrine's Bavituximab Equivalent Can Generate Curative Immune Responses as Part of a Vaccine-Like Regimen in Preclinical Models of Aggressive Brain Cancer EPIX Pharmaceuticals Announces Statistically Significant Results in Cognitive Function from Phase 1b Clinical Trial of Novel 5-HT6 Drug Candidate Aeolus Pharmaceuticals' AEOL 10150 Highlighted in Nature Genetics Publication Ferring Reports on ENDOMETRIN Presentations at Pacific Coast Reproductive Society Annual Meeting Nymox Reports Completion of New 42 Month Follow-up Study of NX-1207 for BPH Helix BioMedix to Discuss Potential of Its Proprietary Peptides at the BIO International Convention Innovive Pharmaceuticals Announces Preclinical Data from INNO-206 Oncology Program Viventia biotech reports synergystic effect of its Proxinium antibody in combinaton with chemotherapy and radiation Adventrx Announces Positive Data From Multidrug Therapy With CoFactor Seattle Genetics Highlights Data on its Proprietary Antibody-Drug Conjugate Technology at AACR Santaris Pharma presents positive preclinical data on SPC2996 at the American Association for Cancer Research Micromet and MedImmune Present Data From Preclinical Study of New BiTE Molecule Targeting CEA Protalix BioTherapeutics, Inc. Receives Approval from the FDA to Initiate a Phase III Clinical Trial of prGCD Favrille Announces Results From Study Showing Enhanced Activity From Insect Cell-Derived Immunotherapy for Lymphoma Kosan Presents Preclinical Data on Nuclear Export Inhibitors, Novel Anticancer Agents, at AACR Data Presented at AACR Meeting Shows Peregrine's Immunocytokine Fusion Proteins Reduce Growth of B-Cell Lymphoma Tumors by 85% in Preclinical Studies Micell Technologies Presents Data on Novel Drug-Eluting Stents FDA Announces Change of Location Notice for Upcoming Advisory Committee Meeting Gloucester Pharmaceuticals Reports on Romidepsin and Erlotinib Combination in Non-Small Cell Lung Cancer Presented at American Association of Cancer Research Annual Meeting Myriad Genetics Presents Tumor Origin Technology at AACR Novel Human Tissue Transgenic Cancer Model May Offer Significant Advance Toward Accurately Modeling Human Cancer

April 19

Antares Pharma Announces Positive Results from Application Site Study for Anturol ImClone Systems Showcases Extensive Research and Development Program at the AACR Annual Meeting Allos Therapeutics' PDX Granted Orphan Medicinal Product Designation by the European Commission MedImmune and Micromet Publish Data on Novel Anti-Cancer BiTE Molecule CuraGen and TopoTarget Announce New Clinical Results With Belinostat to be Reported at Upcoming Major Medical Meetings EntreMed Presents Preclinical Data for MKC-1 in Hematological Cancers Abraxis BioScience Presents Pre-Clinical Findings That Support Role of SPARC Expression in Cancer and the Role of the Nanoparticle Albumin Bound (nab) Technology Platform in Targeting the Pathway Abraxis BioScience Presents Results from Pre-Clinical Study That Demonstrates nab-Rapamycin's Robust Antitumor Properties and Ability to Target Intracellular Sites Such as the mTOR Pathway Othera Pharmaceuticals Announces Upcoming Presentation Based Upon Expanded Understanding of Lead Compound Mechanism of Action Abraxis BioScience Presents Data from Pre-Clinical Study That Provide Evidence for Chemotherapy-Induced Angiogenesis and Rationale for Combining nab-Paclitaxel (Abraxane) with Anti-Angiogenic Agents to Increase Tumor Response Data Show SuperGen's Multi-Targeted Tyrosine Kinase Inhibitor Suppresses Critical Double-Stranded DNA Repair Protein, Rad51 Clinical Update - Debio 025 Cyclophilin Inhibitor for the Treatment of HCV King Pharmaceuticals Announces Plan to Report Positive Data from Phase III Clinical Trial Evaluating the Combination of Altace with Hydrochlorothiazide Aranesp ``145 Study'' Shows No Difference in Survival in Patients with Small-Cell Lung Cancer Spectrum Pharmaceuticals Announces Data From Three Oncology Programs Presented at the American Association of Cancer Research Annual Meeting Aeolus Pharmaceuticals' AEOL 10113 Demonstrates Potential as a Protector of Healthy Normal Cells from Cancer Radiation Therapy Lexicon-Genentech Collaboration Yields Potential Therapeutic Targets Critical Therapeutics Announces the Publication of New Preclincial HMGB1 Data in Nature Immunology Idenix Announces Data Presentations at the 2007 Digestive Disease Week Meeting MedImmune Publishes New Data in Nature Immunology Demonstrating The Role HMGB1 May Play in Systemic Autoimmune Diseases LANI completes Phase I in Japan and to commence Phase I in UK VioQuest Pharmaceuticals Announces Data Presentation for Its Akt Inhibitor VQD-002, at American Association for Cancer Research Annual Meeting

April 20

Addex Reports Positive Results in Phase IIa Clinical Trial With ADX10059 in Migraine Gilead Announces Presentation of Positive Phase III Data on Aztreonam Lysine for Inhalation in Patients With Cystic Fibrosis New Anti-Rejection Medication 6-Month Results for Heart Transplant Recipients to Be Released at International Heart and Lung Transplant Meeting Mode of Action of EpiCept-Licensed Cancer Compound Profiled at AACR The Lancet Publishes PREVAIL Study Results Showing Lovenox Superiority Over Unfractionated Heparin for Reducing the Risk of Venous ThromboEmbolism in Patients With Acute Ischemic Stroke UCB Announces Positive Top-Line Phase III Results for Keppra as Adjunctive Therapy for Partial Onset Seizures in Paediatric Patients from One Month to Less than Four Years of Age Baxter Presents Phase I Inhaled Insulin Study Results at Respiratory Drug Delivery Conference Peregrine Pharmaceuticals Highlights Significant Advances in the Company's Clinical and Preclinical Cancer Programs Presented This Week at the AACR Annual Meeting FDA Announces Audio Broadcasts on Emerging Drug Safety Information

April 23

Micromet Achieves Milestone in BiTE Research Collaboration with MedImmune Positive Results Using Affitech-Identified Human Antibody That Blocks VEGF Binding to VEGF Receptor 2 in Preclinical Cancer Model Reported by Peregrine Ceragenix Announces New Publication of Scientific Research on Ceragenin Technology Affymax Announces Phase 2 Clinical Trial Results of Once-Per-Month Hematide for the Treatment of Anemia in Patients with Early- and End-Stage Chronic Kidney Disease CytRx Announces RNAi Delivery Nanoparticle Technology Exclusively Licensed to Subsidiary, RXi Pharmaceuticals, Described in Peer-Reviewed Journal Sirion Therapeutics Announces Clinical Data to be Presented at the 2007 Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting FDA MedWatch: Avastin (bevacizumab) and Formation of Tracheoesophageal Fistula in a Recent Clinical Study in Patients with Limited-stage Small Cell Lung Cancer Mircera Effective in Stabilising Haemoglobin Levels in Elderly Patients With Kidney Disease on Dialysis Cellerant Therapeutics Reversed Autoimmune Disease in Lupus Mice with Transplant of Purified Donor Blood Stem Cells Aeolus Pharmaceuticals' AEOL 10113 May Play an Important Role Regulating the Oxidative Damage Induced by Ionizing Radiation Targeting Specific Mutations Reveals Promising New Approach to Treating Genetic Disorders; Preclinical Data Published in Nature Gentium's Defibrotide Highlighted in Poster Presentation at World Congress of Nephrology

April 24

April 25

Telomerase Presentations at the AACR 2007 Annual Meeting Acorda Therapeutics to Host Analyst and Investor Reception BDSI Announces Positive Phase III Clinical Trial Results for BEMA Fentanyl ADVENTRX Announces Positive Data From Preclinical Pharmacokinetic Testing of ANX-514 (Docetaxel Emulsion) Basilea Reports Positive Re-treatment Results from a Second Phase III Trial of Alitretinoin for Patients with Severe Chronic Hand Eczema XenoPort Reports Positive Top-Line Phase 3 Trial Results of XP13512 in Restless Legs Syndrome DuoCort AB: DuoCort announces Phase I Data Presentation at the European Congress of Endocrinology Reata's Synthetic Triterpenoids Profiled in Nature Reviews Cancer OSI Pharmaceuticals Announces Pivotal Phase III Tarceva Study Published in the Journal of Clinical Oncology Showed Survival Improvement in Patients with Pancreatic Cancer New Data on Genmab and GlaxoSmithKline's Ofatumumab: Phase II Study in Rheumatoid Arthritis to be Presented at EULAR Bipolar Disorder in Children Difficult to Diagnose, Reports the Harvard Mental Health Letter Preclinical Studies Identify Novel Approach for Enhancing the Anticancer Activity of Introgen's INGN 241 Labtec’s Next Generation Pain Patch Successful in Clinical Studies

April 26

Columbia Laboratories Reports Preliminary Findings from the Ongoing Data Analysis of the Phase III Clinical Study of PROCHIEVE 8% (progesterone gel) to Prevent Preterm Birth Major Manufacturer of Unapproved and Adulterated Drugs Iomai Dose-Ranging Trial Demonstrates Needle-Free Patch Vaccine for Travelers' Diarrhea Stimulates Immune Response Even at Low Doses Study Demonstrating Aeolus Compound's Neuroprotection in Parkinson's Disease Published in the Journal of Neuroscience Study Supports Cost-Effectiveness of Medtronic's Spasticity Treatment for Children with Cerebral Palsy Alchemia Reports Preliminary Positive Efficacy Data From HyCAMP Phase II Trial Ties Between Physicians and Drug Companies Still Too Strong: the Prescription Project Offers Solutions to Prevent Conflicts of Interest Schepens Scientists Identify Key to Integrating Transplanted Nerve Cells Into Injured Tissue FDA approves IND on Lead Product M6G Two-year data for Angiotech's Vascular Wrap Paclitaxel-Eluting Mesh to be Presented at European Vascular Symposium Researchers Identify New Genetic Risk Factors for Type 2 Diabetes

April 27

First Controlled Large-Scale Intervention Angiotensin Receptor Blocker (ARB) Trial in a Japanese Population, JIKEI HEART Study Demonstrates Significant Reduction in Blood Pressure and Protection of Organs with Valsartan Doctors Outraged Over Growth Hormone Controversy Northfield Laboratories Investor Update Diovan Achieved 40% Reduction in Stroke and Cardiovascular Events in Landmark Jikei Heart Study Diovan Achieved 40% Reduction in Stroke and Cardiovascular Events in Landmark Jikei Heart Study Human Genome Sciences Reports Growing Evidence That Its TRAIL Receptor Antibodies Have Significant Potential in the Treatment of a Broad Range of Cancers SciClone Announces ZADAXIN and SCV-07 Abstracts Accepted at ASCO Merck Serono Announces Presentation of Phase III Clinical Data on Safinamide in Parkinson’s Disease at the American Academy of Neurology 59th Annual Meeting

Clinical Trial Results Archive

2005

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