Medarex Announces Presentations at Annual Meeting of the American Association for Cancer Research

PRINCETON, N.J., March 17, 2008 /PRNewswire-FirstCall/ -- Medarex, Inc. announced today that the following clinical and preclinical abstracts are expected to be the subject of oral or poster presentations at the Annual Meeting of the American Association for Cancer Research (AACR), being held April 12-16, 2008 in San Diego:

    -- "Dendritic and T cell functions in patients with metastatic hormone-

       refractory prostate cancer treated with GVAX immunotherapy for prostate

       cancer and ipilimumab" (Abstract #2538, Clinical Immunotherapy Session)

       - Oral presentation scheduled for Monday, April 14, 2008 at 1:25 p.m.


    -- "CTLA-4 blockade for hormone refractory prostate cancer: dose-dependent

       induction of CD8+ T cell activation and clinical responses" (Abstract

       #2539, Clinical Immunotherapy Session) - Oral presentation scheduled

       for Monday, April 14, 2008 at 1:40 p.m.


    -- "Increased doses of an anti-CD30 antibody, MDX-060, results in

       prolonged progression free survival in subjects with CD30 positive

       lymphoma" (Abstract #5525, Phase 2 and 3 Clinical Trials 3: Blood,

       Lung, Brain/CNS and Sarcoma Session) - Poster session scheduled for

       Wednesday, April 16, 2008 at 8:00 a.m.


    -- "Preclinical development of anti B7-H4 therapeutic antibodies"

       (Abstract #4986, Developmental Immunotherapy Session) - Oral

       presentation scheduled for Tuesday, April 15, 2008 at 2:25 p.m.


    -- "Human antibody conjugates of potential utility for prostate cancer

       therapy: a comparison of MGBA conjugates with antibodies targeting a

       cell surface target (prostate-specific membrane antigen) and an extra-

       cellular target (Mindin/RG1)" (Abstract #4062, Immunoconjugates,

       Peptides, and Protein Therapeutics Session) - Poster session scheduled

       for Tuesday, April 15, 2008 at 8:00 a.m.


    -- "Efficacy and safety of a human anti-CD70 antibody-MGBA conjugate"

       (Abstract #4061, Immunoconjugates, Peptides, and Protein Therapeutics

       Session) - Poster session scheduled for Tuesday, April 15, 2008 at 8:00

       a.m.


    -- "Mechanism of activation of a human anti-CD70 antibody-MGBA conjugate

       and efficacy in a nude rat model of renal carcinoma" (Abstract #4057,

       Immunoconjugates, Peptides, and Protein Therapeutics Session) - Poster

       session scheduled for Tuesday, April 15, 2008 at 8:00 a.m.


    -- "Ptk7 as a direct and tumor stroma target in multiple solid

       malignancies" (Abstract #1526, Targets and Screening Approaches

       Session) - Poster session scheduled for Sunday, April 13, 2008 at 1:00

       p.m.

Abstracts and information about the AACR and its Annual Meeting may be found at www.aacr.org.

About Medarex

Medarex is a biopharmaceutical company focused on the discovery, development and potential commercialization of fully human antibody-based therapeutics to treat life-threatening and debilitating diseases, including cancer, inflammation, autoimmune disorders and infectious diseases. Medarex applies its UltiMAb(R) technology and product development and clinical manufacturing experience to generate, support and potentially commercialize a broad range of fully human antibody product candidates for itself and its partners. More than 40 of these therapeutic product candidates derived from Medarex technology are in human clinical testing or have had INDs submitted for such trials, with seven of the most advanced product candidates currently in Phase 3 clinical trials or the subject of regulatory applications for marketing authorization. Medarex is committed to building value by developing a diverse pipeline of antibody products to address the world's unmet healthcare needs. For more information about Medarex, visit its website at www.medarex.com.

Medarex(R), the Medarex logo and UltiMAb(R) are registered trademarks of Medarex, Inc. All rights are reserved.

CONTACT: Laura S. Choi, Investor Relations, +1-609-430-2880, Ext. 2216, orJean Mantuano, Corporate Communications (media), +1-609-430-2880, Ext.2221, both of Medarex, Inc.

Web site: http://www.medarex.com/

Company News On-Call: http://www.prnewswire.com/comp/108265.html/

Ticker Symbol: (NASDAQ-NMS:MEDX)

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Posted: March 2008

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