CYT003-QbG10 to treat allergy to be presented at the Congress of the European Academy of Allergology and Clinical Immunology (EAACI), June 9-13, 2007

Zurich, June 1, 2007-Cytos Biotechnology AG is delighted to inform you about the upcoming scientific presentations of its novel immunotherapeutic CYT003-QbG10 to treat allergic diseases. Recently, positive clinical results for CYT003-QbG10 were obtained and will be presented in different sessions at the XXVI Congress of the European Academy of Allergology and Clinical Immunology (EAACI), taking place from June 9-13, 2007 in Göteborg, Sweden. The EAACI Congress has developed into one of the most important annual events in the field of Allergy in the world. For more information please visit ww.congrex.com/eaaci2007.

CYT003-QbG10 presentations at EAACI 2007: 1) Oral presentation of Abstract No. 146: Dust mite allergy - new treatment options. Dr. med. Thomas Kündig, Head of Research, Department of Dermatology, University Hospital Zurich, Switzerland will present the CYT003-QbG10 study findings relating to house dust mite allergy on Tuesday, June 12, 2007; Oral Abstract Session 26 - Novel developments in basic allergology; 3.30 - 5.00 pm (CET).

2) Poster presentation of Abstract No. 183: A double-blind, placebo-controlled phase IIa study investigating CYT003-QbG10 as a novel allergen-independent immunotherapy in patients suffering from grass pollen allergy. Presentation is on Sunday, June 10, 2007; Poster Discussion Session 1 - Immunotherapy; 10.00 - 12.00 am (CET).

3) Poster presentation of Abstract No. 714: A double-blind, placebo-controlled phase IIa study investigating CYT003-QbG10 as a novel immunotherapy in patients suffering from house dust mite allergy. Presentation is on Sunday, June 10, 2007; Poster Session - Allergen SIT IV; 12.00 -1.30 pm (CET).

Background: CYT003-QbG10 is an immunotherapeutic product in development for the treatment of allergy, asthma and atopic dermatitis. It consists of the Immunodrug™ QbG10 which is comprised of the virus-like particle Qb filled with a synthetic immunostimulatory DNA sequence called G10. CYT003-QbG10 is designed as a disease-modifying treatment and aims to induce a potent Th1 type immune response in order to suppress an "allergic" Th2 type immune response. An earlier, open-label phase IIa study with CYT003-QbG10 combined with an allergen extract of house dust mites at a standard dose showed excellent long-term efficacy in patients allergic to dust mites. Furthermore, two placebo-controlled phase IIa studies with CYT003-QbG10 delivered positive results in patients suffering from allergic rhinitis due to grass pollen allergy and house dust mite allergy. CYT003-QbG10 is currently being studied in clinical trials for the treatment of allergic rhinitis and atopic dermatitis.

Please feel free to contact us at the address below should you wish to receive further information, address questions, or arrange meetings with Cytos Biotechnology directly.

With best regards,

Claudine Blaser

For more information please contact:

Claudine Blaser, PhD Director Corporate Communications Cytos Biotechnology AG Wagistrasse 25, Postfach CH-8952 Schlieren (Zurich) Tel. +41 44 733 47 20 Fax. +41 44 733 47 18 e-mail: claudine.blaser@cytos.com www.cytos.com

 

Posted: June 2007

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