This Book Meets The Long Awaited Need For A Comprehensive Overview Of The Biological Role Of High Density Lipoproteins

DUBLIN, Ireland--(BUSINESS WIRE)--Nov 6, 2007 - Research and Markets (http://www.researchandmarkets.com/reports/c73750) has announced the addition of "High-Density Lipoproteins: From Basic Biology to Clinical Aspects" to their offering.

In 20 chapters by biological and biomedical researchers, the current knowledge on high density lipoprotein (HDL) is summarized. The biological part discusses the formation, turnover, and regulation HDL as known from recent studies. In the medically oriented part, the numerous functions of HDL in controlling blood cholesterol and its role in common diseases - such as diabetes, cancer and metabolic syndrome - are analyzed, including strategies for pharmaceutical intervention.

This book meets the long-awaited need for a comprehensive overview of the biological role of HDLs. Edited by one of the pioneers in HDL and cholesterol research, this monograph summarizes current knowledge on HDL turnover, regulation and physiology. Clearly structured, the various sections cover HDL structure, formation, secretion and removal, as well as plasma metabolic factors. The biological activities and clinical aspects are equally discussed, as is the impact of HDL on common diseases and their prevention.

About the Author

Christopher Fielding is Neider Professor of Cardiovascular Physiology at the University of California at San Francisco (UCSF). He graduated from University College in London (UK) where he also received his PhD. After appointments at Oxford University and at the University of Chicago, he joined the faculty at UCSF in 1971, being appointed full professor in 1985.

Professor Fielding is a pioneer in the HDL field who developed many of the current concepts in HDL metabolism and its role in health and disease.

Contents:

HDL STRUCTRE

Apolipoprotein A1

Apolipoprotein A2

Apolipoprotein E

Apolipoprotein M

HDL PLASMA METABOLIC FACTORS

ABC Transporters

Apo A1 Recycling and LCAT

CETP, PLTP and Enothelial Lipase

Phospholipid Transfer Proteins

HDL Remodelling by Lipases

HDL FORMATION, SECRETION, REMOVAL

Apo A1 Synthesis and Secretion

Mouse Models of HDL Synthesis and Secretion

Hepatic and Renal HDL Receptors

BIOLOGICAL ACTIVITIES OF HDL

HDL and Inflammation

HDL and Exercise

HDL and Endothelium

Apo A1 and Nutrition

Nutrition and HDL Speciation

CLINICAL ASPECTS OF HDL

HDL in Metabolic Syndromes

HDL and Genetics

HDL and Atherosclerosis

HDL-raising Drugs

For more information visit http://www.researchandmarkets.com/reports/c73750

Contact

Research and Markets
Laura Wood
Senior Manager
Fax: +353 1 4100 980
press@researchandmarkets.com

Posted: November 2007

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