ASBMR Task Force Reviewing Link Between Fractures and Bisphosphonate Therapy
International Group to Present Findings This Fall; Issues Interim Guidance
WASHINGTON--(BUSINESS WIRE)--Mar 11, 2010 - Recent reports suggesting a link between long-term bisphosphonate usage and rare bone fractures have sparked rising concern among patients, health care professionals and the public. The American Society of Bone and Mineral Research (ASBMR) is examining this urgent clinical issue and will present its findings later this year.
The ASBMR is a professional, scientific and medical society that brings together clinical and experimental scientists involved in the study of bone and mineral metabolism. A multidisciplinary, international task force set up by the group will present its findings at ASBMR's Annual Meeting in Toronto October 15-19.
Studies have found that bisphosphonates significantly reduce the risk of broken bones in people with osteoporosis. Patients taking bisphosphonates are typically at a higher risk of breaking a bone without treatment. Existing data suggest a very low risk of developing atypical femoral fractures for patients taking bisphosphonates for osteoporosis.
Elizabeth Shane, MD, Co-Chair of the ASBMR Task Force states: “The published and unpublished data that we've reviewed indicate that these fractures affect fewer than 1 in 10,000 patients on bisphosphonates. Many more fractures of the hip, spine, and other sites are prevented by bisphosphonates than the number of atypical fractures seen. The risk-benefit ratio, therefore, clearly favors treating patients who have osteoporosis with bisphosphonates.”
Until the ASBMR Task Force completes its work and issues its report, it urges patients and healthcare professionals to follow the recently released guidance by the U.S. Food and Drug Administration (FDA).
If you're a patient taking oral bisphosphonates you should:
Healthcare professionals are advised to:
The American Society Bone and Mineral Research (ASBMR) is the premier professional, scientific and medical society established to promote excellence in bone and mineral research and to facilitate the translation of that research into clinical practice. The ASBMR has a membership of nearly 4,000 physicians, basic research scientists, and clinical investigators from around the world.
Contact: Douglas Fesler
Posted: March 2010