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Clindesse Cream

Generic name: Clindamycin Vaginal Cream (One-Dose)klin-da-MYE-sin ]
Drug class: Vaginal anti-infectives

Medically reviewed by Judith Stewart, BPharm. Last updated on Sep 25, 2023.

What is Clindesse?

Clindesse is a single-dose therapy used to treat vaginal infections (bacterial vaginosis) caused by certain bacteria in non-pregnant women.

Clindesse Cream is a topical lincomycin antibiotic. It works by slowing the growth of certain bacteria. The recommended dose is a single applicatorful at any time of the day.

Clindesse may also be used for purposes other than those listed in this medication guide.

Do NOT use Clindesse if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Clindesse:

Some medical conditions may interact with Clindesse. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Clindesse. Because little, if any, clindamycin is absorbed into the blood, the risk of it interacting with another medicine is low.

This may not be a complete list of all interactions that may occur. Ask your health care provider if this medication may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Clindesse:

Use Clindesse as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Clindesse.

Important safety information:

Possible side effects of Clindesse:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Fungal infection; genital itching or burning; inflammation or pain; vaginal discharge.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood/mucus in stool; diarrhea; new or worsening vaginal or vulvar itching; painful sex; stomach cramps/pain; white vaginal discharge.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Clindesse may be harmful if swallowed.

Proper storage of Clindesse:

Store Clindesse Cream at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store in a tightly-closed container away from heat and light. Protect from freezing. Keep Clindesse out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Clindesse. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: March 5, 2008
Database Edition 08.1.1.003
Copyright 2023 Wolters Kluwer Health, Inc.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.