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Heparin-induced Thrombocytopenia


Heparin-induced thrombocytopenia (HIT) is a condition that causes a decrease of platelets in the blood. Platelets help the blood clot. HIT usually occurs after you are treated with heparin.



You may need any of the following:

  • Blood thinners help prevent blood clots. Examples of blood thinners include heparin and warfarin. Clots can cause strokes, heart attacks, and death. The following are general safety guidelines to follow while you are taking a blood thinner:

    • Watch for bleeding and bruising while you take blood thinners. Watch for bleeding from your gums or nose. Watch for blood in your urine and bowel movements. Use a soft washcloth on your skin, and a soft toothbrush to brush your teeth. This can keep your skin and gums from bleeding. If you shave, use an electric shaver. Do not play contact sports.

    • Tell your dentist and other healthcare providers that you take anticoagulants. Wear a bracelet or necklace that says you take this medicine.

    • Do not start or stop any medicines unless your healthcare provider tells you to. Many medicines cannot be used with blood thinners.

    • Tell your healthcare provider right away if you forget to take the medicine, or if you take too much.

    • Warfarin is a blood thinner that you may need to take. The following are things you should be aware of if you take warfarin.

      • Foods and medicines can affect the amount of warfarin in your blood. Do not make major changes to your diet while you take warfarin. Warfarin works best when you eat about the same amount of vitamin K every day. Vitamin K is found in green leafy vegetables and certain other foods. Ask for more information about what to eat when you are taking warfarin.

      • You will need to see your healthcare provider for follow-up visits when you are on warfarin. You will need regular blood tests. These tests are used to decide how much medicine you need.

  • Antiplatelets , such as aspirin, help prevent blood clots. Take your antiplatelet medicine exactly as directed. These medicines make it more likely for you to bleed or bruise. If you are told to take aspirin, do not take acetaminophen or ibuprofen instead.

  • Take your medicine as directed. Call your healthcare provider if you think your medicine is not helping or if you have side effects. Tell him if you are allergic to any medicine. Keep a list of the medicines, vitamins, and herbs you take. Include the amounts, and when and why you take them. Bring the list or the pill bottles to follow-up visits. Carry your medicine list with you in case of an emergency.

Tell all healthcare providers about your reaction to heparin:

You may want to carry a medical card or wear medical alert jewelry.

Follow up with your healthcare provider as directed:

You will need to return for blood tests. Write down your questions so you remember to ask them during your visits.

Contact your healthcare provider if:

  • You have a fever.

  • You have numbness in your arms or legs.

  • You have severe pain in your arms or legs that does not go away.

  • You have trouble standing and walking.

  • You have questions or concerns about your condition or care.

Return to the emergency department if:

  • You feel lightheaded, short of breath, and have chest pain.

  • You cough up blood.

  • Your arm or leg feels warm, tender, and painful. It may look swollen and red.

  • You have any of the following signs of a heart attack:

    • Squeezing, pressure, or pain in your chest that lasts longer than 5 minutes or returns

    • Discomfort or pain in your back, neck, jaw, stomach, or arm

    • Trouble breathing

    • Nausea or vomiting

    • Lightheadedness or a sudden cold sweat, especially with chest pain or trouble breathing

© 2015 Truven Health Analytics Inc. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. All illustrations and images included in CareNotes® are the copyrighted property of A.D.A.M., Inc. or Truven Health Analytics.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

Learn more about Heparin-induced Thrombocytopenia (Aftercare Instructions)