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Zymine syrup

Generic Name: triprolidine (trye-PROE-li-deen)
Brand Name: Zymine

Zymine syrup is used for:

Preventing or treating symptoms of hay fever and other upper respiratory allergies or the common cold, such as runny nose, sneezing, itching of the nose and throat, and itchy, watery eyes, and relieving cough. It may also be used for other conditions as determined by your doctor.

Zymine syrup is an antihistamine. It works by blocking the action of histamine, reducing the symptoms of an allergic reaction.

Do NOT use Zymine syrup if:

  • you are allergic to any ingredient in Zymine syrup or other similar medicines
  • you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Video: Asthma

How to prevent and treat an asthma attack.

Before using Zymine syrup:

Some medical conditions may interact with Zymine syrup. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a fast, slow, or irregular heartbeat
  • if you have a history of asthma; chronic obstructive pulmonary disease (COPD); chronic bronchitis; lung problems (eg, emphysema); shortness of breath; sleep apnea; heart blood vessel problems; stroke; seizures; a blockage of your stomach, intestine, or bladder; difficulty urinating; diabetes; ulcers; an enlarged prostate or other prostate problems; glaucoma; heart problems; high blood pressure; porphyria; phenylketonuria; or an overactive thyroid

Some MEDICINES MAY INTERACT with Zymine syrup. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Sodium oxybate (GHB) because an increase in sleep duration and a decrease in the ability to breathe are likely to occur
  • Monoamine oxidase (MAO) inhibitors (eg, phenelzine) because they may increase side effects of Zymine syrup

This may not be a complete list of all interactions that may occur. Ask your health care provider if Zymine syrup may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Zymine syrup:

Use Zymine syrup as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Zymine syrup may be taken with or without food.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • Use Zymine syrup exactly as directed on the package, unless instructed differently by your doctor. If you are taking Zymine syrup without a prescription, follow any warnings and precautions on the label.
  • If you miss a dose of Zymine syrup and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Zymine syrup.

Important safety information:

  • Zymine syrup may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Zymine syrup. Using Zymine syrup alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Zymine syrup. Zymine syrup will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
  • Zymine syrup may cause dizziness. Alcohol, hot weather, exercise, and fever can increase this effect. To prevent it, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness.
  • Do not become overheated in hot weather or during exercise or other activities since heatstroke may occur.
  • If you are scheduled for allergy skin testing, do not take Zymine syrup for several days before the test because it may decrease your response to the skin tests.
  • Phenylketonuria patients - Zymine syrup contains phenylalanine.
  • If you are using Zymine syrup for cough, cold, or allergy symptoms, stop use and contact your doctor if your symptoms do not improve within 7 days or are accompanied by fever.
  • Use Zymine syrup with caution in the ELDERLY because they may be more sensitive to its effects, especially dizziness, sedation, and lightheadedness upon standing.
  • Safe use and instructions for use in CHILDREN differs according to the brand used. Talk to your doctor or pharmacist if you have any questions about the brand you are using.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Zymine syrup during pregnancy. Zymine syrup is excreted in breast milk. If you are or will be breast-feeding while you are using Zymine syrup, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Zymine syrup:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; dry mouth, throat, and nose; excitability; thickening of mucus in nose or throat.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); convulsions; fast heartbeat or pounding in the chest; decreased alertness; hallucinations; tremor; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch .

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; excitement; hallucinations; loss of consciousness; muscle twitching; seizures; tremor; weakness.

Proper storage of Zymine syrup:

Store Zymine syrup at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Zymine syrup out of the reach of children and away from pets.

General information:

  • If you have any questions about Zymine syrup, please talk with your doctor, pharmacist, or other health care provider.
  • Zymine syrup is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Zymine syrup. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

Severe allergies and anaphylaxis: Learn how epinephrine can save a life. Watch Video

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