Zylet drops

Generic Name: loteprednol/tobramycin (LOE-te-PRED-nol/TOE-bra-MYE-sin)
Brand Name: Zylet

Zylet drops is used for:

Treating certain types of eye inflammation in which an infection or risk of infection is present.

Zylet drops is a combination of a corticosteroid and antibiotic. It reduces inflammation and treats or protects against infection due to certain bacteria.

Do NOT use Zylet drops if:

  • you are allergic to any ingredient in Zylet drops or to similar medicines, including corticosteroids or aminoglycoside antibiotics.
  • you have a viral disease in the eye, including herpes simplex keratitis (dendritic keratitis), vaccinia, or varicella
  • you have a mycobacterial or fungal infection of the eye

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: 2014 Update - First Time Brand-to-Generic Switches

Before using Zylet drops:

Some medical conditions may interact with Zylet drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have glaucoma, thinning of certain parts of the eye (the cornea or the sclera), or a history of herpes simplex infection, or have recently had cataract surgery
  • if you have diabetes or wear contact lenses

Some MEDICINES MAY INTERACT with Zylet drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Certain diuretic medicines (eg, furosemide), cyclosporine, nonsteroidal anti-inflammatory medicines (NSAIDs) (eg, ibuprofen), or other medicines containing aminoglycoside antibiotics (eg, tobramycin, gentamicin) because the risk of their side effects may be increased by Zylet drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if Zylet drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Zylet drops:

Use Zylet drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Zylet drops is to be used as eye drops. It is not to be injected into the eye.
  • Shake well before each use.
  • To use Zylet drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
  • To clear up your infection completely, use Zylet drops for the full course of treatment. Keep using it even if you feel better in a few days.
  • Zylet drops is usually used for a maximum of 2 weeks. If it is used for longer than 10 days, eye exams may be required.
  • If you miss a dose of Zylet drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Zylet drops.

Important safety information:

  • Zylet drops may cause blurred vision. Use Zylet drops with caution. Do not drive or perform other possibly unsafe tasks if you cannot see clearly.
  • If your symptoms do not get better after 2 days or if they get worse, contact your health care provider.
  • Soft contact lenses may absorb a chemical in Zylet drops. Do not wear contact lenses while you are using Zylet drops.
  • Tell your doctor or dentist that you take Zylet drops before you receive any medical or dental care, emergency care, or surgery.
  • Zylet drops only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Be sure to use Zylet drops for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of Zylet drops may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Lab tests, including eye exams, may be performed while you use Zylet drops. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zylet drops while you are pregnant. It is not known if Zylet drops is found in breast milk. If you are or will be breast-feeding while you use Zylet drops, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Zylet drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning or stinging upon using Zylet drops; mild itching, discomfort, or redness of the eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; sensitivity to light; severe or worsening pain or inflammation, redness, swelling, or discharge from the eye or eyelid; unusual tearing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Zylet drops:

Store upright, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Do not freeze. Keep Zylet drops out of the reach of children and away from pets.

General information:

  • If you have any questions about Zylet drops, please talk with your doctor, pharmacist, or other health care provider.
  • Zylet drops is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Zylet drops or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Zylet drops. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Zylet drops. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Zylet drops.

Issue Date: December 3, 2014
Database Edition 14.4.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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