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Zantac 75

Generic Name: ranitidine (ra-NI-ti-deen)
Brand Name: Zantac 75

Zantac 75 is used for:

Treating or preventing heartburn, acid indigestion, and sour stomach caused by certain foods and drinks. It may also be used for other conditions as determined by your doctor.

Zantac 75 is a histamine H2-receptor antagonist. It works by blocking the action of histamine in the stomach. This reduces the amount of acid the stomach makes, which helps to relieve symptoms of heartburn, acid indigestion, and sour stomach.

Do NOT use Zantac 75 if:

  • you are allergic to any ingredient in Zantac 75 or other H2-receptor antagonists (eg, famotidine)
  • you have a history of the blood disease porphyria
  • you have trouble swallowing
  • you are taking dasatinib

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: Is it Safe to Give Human Medicine to Pets?

Always get your pet's drug and dose recommendation from the veterinarian.

Before using Zantac 75:

Some medical conditions may interact with Zantac 75. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of kidney or liver problems
  • if you have frequent wheezing or chest pain; chest or shoulder pain with shortness of breath; pain spreading to your arm, neck, or shoulder; lightheadedness; nausea or vomiting; or sudden increased sweating
  • if you have painful swallowing, vomit with blood, black or bloody stools, or severe or persistent heartburn

Some MEDICINES MAY INTERACT with Zantac 75. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Certain benzodiazepines (eg, midazolam, triazolam), glipizide, procainamide, or warfarin because the risk of their side effects may be increased by Zantac 75
  • Dasatinib, delavirdine, gefitinib, certain HIV protease inhibitors (eg, atazanavir), itraconazole, or ketoconazole because their effectiveness may be decreased by Zantac 75

This may not be a complete list of all interactions that may occur. Ask your health care provider if Zantac 75 may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Zantac 75:

Use Zantac 75 as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • If you are using Zantac 75 to treat symptoms, take it by mouth with or without food.
  • If you are using Zantac 75 to prevent symptoms, take it by mouth 30 to 60 minutes before eating food or drinking beverages that cause your symptoms.
  • Take Zantac 75 with a full glass of water (8 oz/240 mL).
  • If you also take itraconazole or ketoconazole, ask your doctor or pharmacist how to take it with Zantac 75.
  • Do not take other antacids while you are using Zantac 75 without first checking with your doctor.
  • Continue to take Zantac 75 even if you feel well. Do not miss any doses.
  • If you miss a dose of Zantac 75, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Zantac 75.

Important safety information:

  • Zantac 75 may rarely cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Zantac 75 with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do NOT take more than the recommended dose or use for longer than 14 days without checking with your doctor.
  • If your stomach pain does not get better or if it gets worse, check with your doctor.
  • Zantac 75 may interfere with certain lab tests, including urine protein tests. Be sure your doctor and lab personnel know you are taking Zantac 75.
  • Zantac 75 should not be used in CHILDREN younger than 12 years old without first checking with the child's doctor; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zantac 75 while you are pregnant. Zantac 75 is found in breast milk. If you are or will be breast-feeding while you use Zantac 75, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Zantac 75:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; headache; nausea; stomach upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); change in the amount of urine produced; confusion; dark urine; depression; fast, slow, or irregular heartbeat; fever, chills, or sore throat; hallucinations; severe or persistent headache or stomach pain; unusual bruising or bleeding; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include dizziness; trouble walking.

Proper storage of Zantac 75:

Store Zantac 75 at room temperature, between 68 and 77 degrees (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Zantac 75 out of the reach of children and away from pets.

General information:

  • If you have any questions about Zantac 75, please talk with your doctor, pharmacist, or other health care provider.
  • Zantac 75 is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Zantac 75 or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Zantac 75. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Zantac 75. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Zantac 75.

Issue Date: November 5, 2014
Database Edition 14.4.1.002
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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