Uroxatral

Pronunciation

Generic Name: alfuzosin (al-FUE-zoe-sin)
Brand Name: Uroxatral

Uroxatral is used for:

Treating symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate. It may also be used for other conditions as determined by your doctor.

Uroxatral is an alpha-blocker. It works by blocking receptors in the lower urinary tract, causing smooth muscles in the bladder neck and prostate to relax. This relaxation improves urine flow and reduces the symptoms of BPH.

Do NOT use Uroxatral if:

  • you are allergic to any ingredient in Uroxatral
  • you have moderate to severe liver problems
  • you are taking an alpha-blocker (eg, prazosin), an azole antifungal (eg, ketoconazole), an HIV protease inhibitor (eg, ritonavir), a macrolide antibiotic (eg, erythromycin), nefazodone, or telithromycin

Contact your doctor or health care provider right away if any of these apply to you.

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Before using Uroxatral:

Some medical conditions may interact with Uroxatral. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you will have cataract surgery or other procedures involving the eyes
  • if you have low blood pressure, liver problems, kidney problems, other prostate gland problems, or cancer
  • if you have chest pain or if you or a family member have heart problems (eg, irregular heartbeat, angina)
  • if you take medicine for high blood pressure
  • if you have a history of dizziness, lightheadedness, or fainting, especially after taking certain other medicines

Some MEDICINES MAY INTERACT with Uroxatral. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Alpha-blockers (eg, prazosin), amiodarone, azole antifungals (eg, ketoconazole), beta-blockers (eg, propranolol), HIV protease inhibitors (eg, ritonavir), macrolide antibiotics (eg, erythromycin), nefazodone, nitrates (eg, nitroglycerin), phosphodiesterase type 5 (PDE5) inhibitors (eg, sildenafil), or telithromycin because the risk of side effects, such as severe low blood pressure, may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Uroxatral may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Uroxatral:

Use Uroxatral as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Uroxatral. Talk to your pharmacist if you have questions about this information.
  • Take Uroxatral by mouth with food. Take with the same meal every day.
  • Swallow Uroxatral whole. Do not break, crush, split, or chew before swallowing.
  • Taking Uroxatral at the same time each day will help you remember to take it.
  • Take Uroxatral on a regular schedule to get the most benefit from it.
  • If you miss a dose of Uroxatral, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Uroxatral.

Important safety information:

  • Uroxatral may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Uroxatral with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Uroxatral may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Avoid situations in which injury could occur because of fainting.
  • Contact your doctor immediately if chest pain occurs or worsens.
  • Tell your doctor or dentist that you take Uroxatral before you receive any medical or dental care, emergency care, or surgery.
  • If you have eye surgery for cataract (clouding of the eye) planned, tell your eye doctor that you are using Uroxatral or have taken an alpha-blocker in the past.
  • Uroxatral may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.
  • You will need to have regular check-ups with your doctor while you are using Uroxatral. Be sure to keep all doctor and lab appointments.
  • Uroxatral should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is not known if Uroxatral can cause harm to the fetus. It is not known if Uroxatral is found in breast milk. Uroxatral is not approved for use in women.

Possible side effects of Uroxatral:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; fatigue; headache; stomach pain; stuffy or runny nose.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); back pain; chest pain; dark urine; decreased sexual ability; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; joint pain; painful, prolonged erection; pale stools; severe or persistent dizziness; severe or persistent stomach pain; unusual fatigue or weakness; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Low blood pressure may occur if Uroxatral is taken in higher doses than prescribed. Symptoms may include fainting; irregular heartbeat.

Proper storage of Uroxatral:

Store Uroxatral at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Uroxatral out of the reach of children and away from pets.

General information:

  • If you have any questions about Uroxatral, please talk with your doctor, pharmacist, or other health care provider.
  • Uroxatral is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Uroxatral or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Uroxatral. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Uroxatral. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Uroxatral.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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