Uroxatral

Uroxatral is used for:

Treating symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate. It may also be used for certain conditions as determined by your doctor.

Uroxatral is an alpha-blocker. It works by blocking receptors in the lower urinary tract, causing smooth muscles in the bladder neck and prostate to relax. This relaxation improves urine flow and reduces the symptoms of BPH.

Do NOT use Uroxatral if:

• you are allergic to any ingredient in Uroxatral
• you have moderate to severe liver disease
• you are taking an alpha-blocker (eg, prazosin), an azole antifungal (eg, ketoconazole), or an HIV protease inhibitor (eg, ritonavir)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Uroxatral :

Some medical conditions may interact with Uroxatral . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have low blood pressure, heart problems (eg, irregular heartbeat), kidney problems, other prostate gland problems, or cancer

Some MEDICINES MAY INTERACT with Uroxatral . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Alpha-blockers (eg, prazosin), azole antifungals (eg, ketoconazole), beta-blockers (eg, propranolol), HIV protease inhibitors (eg, ritonavir), or phosphodiesterase type 5 inhibitors (eg, sildenafil) because the risk of side effects, such as severe low blood pressure, may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Uroxatral may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Uroxatral :

Use Uroxatral as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Uroxatral . Talk to your pharmacist if you have questions about this information.
• Take Uroxatral by mouth with food. Take with the same meal every day.
• Swallow Uroxatral whole. Do not break, crush, or chew before swallowing.
• Taking Uroxatral at the same time each day will help you remember to take it.
• Take Uroxatral on a regular schedule to get the most benefit from it.
• If you miss a dose of Uroxatral , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Uroxatral .

Important safety information:

• Uroxatral may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Uroxatral with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Uroxatral may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
• Avoid situations in which injury could occur due to fainting.
• Stop using Uroxatral and contact your health care provider if chest pain occurs or worsens.
• Uroxatral should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss with your doctor the benefits and risks of using Uroxatral while you are pregnant. It is not known if Uroxatral is found in breast milk. If you are or will be breast-feeding while you use Uroxatral , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Uroxatral :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; headache; stuffy nose.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); back pain; chest pain; decreased sexual ability; fainting; fast or irregular heartbeat; joint pain; painful, prolonged erection; severe or persistent dizziness; stomach or abdominal pain; unusual fatigue or weakness.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http: / / www.aapcc.org / dnn / Resources / FindLocalPoisonCenters / tabid / 130 / Default.aspx), or emergency room immediately. Low blood pressure may occur if Uroxatral is taken in higher doses than prescribed. Symptoms may include fainting; irregular heartbeat.

Store Uroxatral at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Uroxatral out of the reach of children and away from pets.

General information:

• If you have any questions about Uroxatral , please talk with your doctor, pharmacist, or other health care provider.
• Uroxatral is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Uroxatral . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

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