Understanding and controlling your respiratory allergies

Triprolidine suspension

Generic Name: triprolidine (trye-PROE-li-deen)
Brand Name: Zymine XR

Triprolidine suspension is used for:

Preventing or treating symptoms of hay fever or other allergies, such as runny nose, sneezing, itching of the nose and throat, and itchy, watery eyes. It may also be used for other conditions as determined by your doctor.

Triprolidine suspension is an antihistamine. It works by blocking the action of histamine, reducing the symptoms of an allergic reaction.

Do NOT use triprolidine suspension if:

  • you are allergic to any ingredient in triprolidine suspension or other similar medicines
  • you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using triprolidine suspension:

Some medical conditions may interact with triprolidine suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a fast, slow, or irregular heartbeat
  • if you have a history of asthma; chronic obstructive pulmonary disease (COPD); chronic bronchitis; lung problems (eg, emphysema); shortness of breath; sleep apnea; heart blood vessel problems; stroke; seizures; a blockage of your stomach, intestine, or bladder; difficulty urinating; diabetes; ulcers; an enlarged prostate or other prostate problems; glaucoma; heart problems; high blood pressure; porphyria; phenylketonuria; or an overactive thyroid

Some MEDICINES MAY INTERACT with triprolidine suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Sodium oxybate (GHB) because an increase in sleep duration and a decrease in the ability to breathe are likely to occur
  • Monoamine oxidase inhibitors (MAOIs) (eg, phenelzine) or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of triprolidine suspension's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if triprolidine suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use triprolidine suspension:

Use triprolidine suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take triprolidine suspension by mouth with or without food.
  • Shake well before each use.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of triprolidine suspension and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use triprolidine suspension.

Important safety information:

  • Triprolidine suspension may cause drowsiness, dizziness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to triprolidine suspension. Using triprolidine suspension alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking triprolidine suspension. Triprolidine suspension will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
  • Triprolidine suspension may cause dizziness. Alcohol, hot weather, exercise, and fever can increase this effect. To prevent it, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness.
  • Do not become overheated in hot weather or during exercise or other activities since heatstroke may occur.
  • If you are scheduled for allergy skin testing, check with your doctor. You may need to stop taking triprolidine suspension for several days before the test because it may decrease your response to the skin tests.
  • Phenylketonuria patients - Triprolidine suspension contains phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.
  • If your symptoms do not get better, or if they get worse, or if they occur with a fever, contact your doctor.
  • Use triprolidine suspension with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness, sedation, and lightheadedness upon standing.
  • Triprolidine suspension should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using triprolidine suspension while you are pregnant. Triprolidine suspension is found in breast milk. Do not breast-feed while you are taking triprolidine suspension.

Possible side effects of triprolidine suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; dry mouth, throat, and nose; excitability; loss of appetite; thickening of mucus in nose or throat.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); convulsions; decreased alertness; fast heartbeat or pounding in the chest; hallucinations; tremor; trouble urinating; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org), or emergency room immediately. Symptoms may include coma; excitement; hallucinations; loss of consciousness; muscle twitching; seizures; tremor; weakness.

Proper storage of triprolidine suspension:

Store triprolidine suspension at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep triprolidine suspension out of the reach of children and away from pets.

General information:

  • If you have any questions about triprolidine suspension, please talk with your doctor, pharmacist, or other health care provider.
  • Triprolidine suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about triprolidine suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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