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Tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine

Generic Name: tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine (TET-a-nus/dif-THEER-ee-a/aye-SELL-yoo-ler per-TUS-is)
Brand Name: Boostrix

Tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine is used for:

Preventing tetanus, diphtheria, and pertussis infections in certain patients.

Tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine is a vaccine. It works by stimulating the body to produce antibodies against tetanus, diphtheria, and pertussis.

Do NOT use tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine if:

  • you are allergic to any ingredient in tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine
  • you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) or an unusual reaction (eg, brain disorder) to any previous dose of this or a similar vaccine
  • you have had a brain disorder (eg, coma, decreased level of consciousness, prolonged seizures) from an unknown cause within 7 days of a previous pertussis-containing vaccine

Contact your doctor or health care provider right away if any of these apply to you.

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Before using tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine:

Some medical conditions may interact with tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances, especially latex
  • if you have had severe pain, swelling, hardening, or bleeding at the injection site within hours of a previous tetanus toxoid-containing vaccine
  • if you have developed any of the following within 48 hours after a previous pertussis-containing vaccine: high fever (greater than 105 degrees F or 40.5 degrees C) from an unknown cause, coma, or persistent crying (for more than 3 hours)
  • if you have a history of seizures (with or without fever) within 3 days of a previous pertussis-containing vaccine
  • if you have a history of Guillain-Barre syndrome, a brain disorder, nervous system problems (eg, seizures), or stroke
  • if you have a fever, infection, or other recent illness; a bleeding disorder (eg, hemophilia) or low blood platelet levels; cancer; a history of poor health; or a weakened immune system (eg, HIV infection, AIDS)
  • if you are undergoing chemotherapy or radiation therapy
  • if you have recently received another vaccine

Some MEDICINES MAY INTERACT with tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Corticosteroids (eg, prednisone), immunosuppressants (eg, cyclosporine), medicines to treat cancer, or other medicines that may weaken the immune system because they may decrease tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine:

Use tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine is given as an injection at your doctor's office, hospital, or clinic.
  • If you miss your dose of tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine, contact your doctor as soon as possible to reschedule your dose.

Ask your health care provider any questions you may have about how to use tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine.

Important safety information:

  • Tell your doctor or dentist that you take tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine before you receive any medical or dental care, emergency care, or surgery.
  • Tell your doctor if you will be receiving other vaccines.
  • Tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine may not protect everyone who receives it from tetanus, diphtheria, or pertussis. Discuss any questions or concerns with your doctor.
  • Tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine is not approved for use in CHILDREN younger than 10 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is not known if tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine while you are pregnant. It is not known if tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine is found in breast milk. If you are or will be breast-feeding while you use tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; headache; mild fever or chills; minor pain, swelling, or redness at the injection site; nausea; stomach pain; tiredness; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blistering, hardening, or sores at the injection site; burning, numbness, or tingling; confusion; fainting; seizures; severe or persistent diarrhea, nausea, or vomiting; severe or persistent fever, chills, headache, or dizziness; severe or persistent joint pain or swelling; severe or persistent muscle aches or weakness; swelling of the injected limb; swollen lymph nodes; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine:

Tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine is usually handled and stored by a health care provider. If you are using tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine at home, store tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine as directed by your pharmacist or health care provider. Protect from light. Keep tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine out of the reach of children and away from pets.

General information:

  • If you have any questions about tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine, please talk with your doctor, pharmacist, or other health care provider.
  • Tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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