Tazarotene gel

Generic Name: tazarotene (taz-AR-oh-teen)
Brand Name: Tazorac

Tazarotene gel is used for:

Treating psoriasis. It may also be used for other conditions as determined by your doctor.

Tazarotene gel is a retinoid. The specific way tazarotene gel works is not completely understood. It may decrease skin inflammation and skin changes associated with psoriasis.

Do NOT use tazarotene gel if:

  • you are allergic to any ingredient in tazarotene gel
  • you are pregnant

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: Psoriasis: Treatment Options to Manage Your Symptoms

Before using tazarotene gel:

Some medical conditions may interact with tazarotene gel. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are planning to become pregnant or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you are of childbearing age
  • if you have eczema, sunburn, or high blood lipid levels, or if you are unusually sensitive to sunlight

Some MEDICINES MAY INTERACT with tazarotene gel. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Fluoroquinolones (eg, levofloxacin), phenothiazines (eg, chlorpromazine), sulfonamides (eg, glipizide, sulfamethoxazole), tetracyclines (eg, doxycycline), thiazide diuretics (eg, hydrochlorothiazide), or vitamin A because the risk of sunburn may be increased by tazarotene gel

This may not be a complete list of all interactions that may occur. Ask your health care provider if tazarotene gel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use tazarotene gel:

Use tazarotene gel as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with tazarotene gel. Talk to your pharmacist if you have questions about this information.
  • Tazarotene gel is for external use only.
  • Apply tazarotene gel using a thin film to cover the lesion only.
  • If a bath or shower is taken before applying tazarotene gel, make sure that the skin is dry before applying tazarotene gel.
  • Do not allow tazarotene gel to come into contact with unaffected skin.
  • Wash your hands immediately after using tazarotene gel, unless you have psoriasis on your hands.
  • If you miss a dose of tazarotene gel, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use tazarotene gel.

Important safety information:

  • If your symptoms do not get better within 4 weeks or if they get worse, check with your doctor.
  • Avoid getting tazarotene gel in your eyes, nose, mouth, vagina, or on healthy skin. If you get tazarotene gel in your eyes, rinse thoroughly with water.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Avoid using other topical medication, cosmetics, or other products that have a strong drying effect. If you have dry skin from using these products, allow your skin to "rest" before using tazarotene gel.
  • Talk with your doctor before you use any other medicines, cleansers, sunscreen or makeup on your skin.
  • Do not use tazarotene gel on skin with eczema, or for any condition other than that for which it was prescribed.
  • If you have a sunburn, do not use tazarotene gel on the sunburned skin until it has fully healed.
  • Weather extremes, such as windy or cold weather, may irritate your skin more while you are using tazarotene gel.
  • If you are using a cream or lotion to soften or moisten your skin, do not apply tazarotene gel until the first cream or lotion has been absorbed into your skin (at least 1 hour).
  • Tazarotene gel may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.
  • Do not cover the treated area with dressings or bandages.
  • Tazarotene gel may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to tazarotene gel. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Tazarotene gel should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
  • Women of childbearing potential should use effective birth control methods (eg, condoms, birth control pills, diaphragms) while using tazarotene gel. You should have a negative pregnancy test 2 weeks before starting tazarotene gel. Contact your health care provider at once if you become pregnant while using tazarotene gel.
  • PREGNANCY and BREAST-FEEDING: Do not use tazarotene gel if you are pregnant. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if tazarotene gel is found in breast milk. Do not breast-feed while taking tazarotene gel.

Possible side effects of tazarotene gel:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bleeding; burning; cracks in skin; dry skin; irritation; itching; peeling; redness; scaling; skin discoloration; skin inflammation; skin pain; stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe or prolonged itching, burning, redness, or peeling; sunburn; swelling of the skin, hands, or feet; worsening of psoriasis.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include severe redness, peeling, or discomfort. Tazarotene gel may be harmful if swallowed.

Proper storage of tazarotene gel:

Store tazarotene gel at 77 degrees F (25 degrees C). Brief storage at temperatures between 23 and 86 degrees F (-5 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep tazarotene gel out of the reach of children and away from pets.

General information:

  • If you have any questions about tazarotene gel, please talk with your doctor, pharmacist, or other health care provider.
  • Tazarotene gel is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take tazarotene gel or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about tazarotene gel. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to tazarotene gel. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using tazarotene gel.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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