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Sodium sulfate/ potassium sulfate/ magnesium sulfate solution

Generic Name: sodium sulfate/potassium sulfate/magnesium sulfate (SOE-dee-um SUL-fate/poe-TAS-ee-um SUL-fate/mag-NEE-zee-um SUL-fate)
Brand Name: Suprep Bowel Prep Kit

Sodium sulfate/ potassium sulfate/ magnesium sulfate solution is used for:

Cleaning out the bowel before a certain procedure (colonoscopy). It may also be used for other conditions as determined by your doctor.

Sodium sulfate/potassium sulfate/magnesium sulfate solution is a laxative. It works by increasing the frequency of bowel movements by retaining water in the stool and by moving contents through the bowel.

Do NOT use sodium sulfate/ potassium sulfate/ magnesium sulfate solution if:

  • you are allergic to any ingredient in sodium sulfate/potassium sulfate/magnesium sulfate solution
  • you have certain stomach or bowel problems (eg, blockage, retention, perforation, toxic inflammation, megacolon, ileus)
  • you have abnormal blood electrolyte levels (eg, potassium, sodium, magnesium)
  • you are using other laxatives or bowel-cleansing products

Contact your doctor or health care provider right away if any of these apply to you.

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Before using sodium sulfate/ potassium sulfate/ magnesium sulfate solution:

Some medical conditions may interact with sodium sulfate/potassium sulfate/magnesium sulfate solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of blood electrolyte problems, seizures, kidney problems, gout, or stomach or bowel problems (eg, inflammatory bowel disease, ulcerative colitis)
  • if you have a history of irregular heartbeat (eg, prolonged QT), a recent heart attack, a certain type of chest pain (unstable angina), or other heart problems (eg, congestive heart failure, heart muscle problems)
  • if you have an impaired gag reflex, trouble swallowing, or gastric reflux, or you are at risk of aspiration (inhaling foreign matter into the airway or lungs)
  • if you are dehydrated or on a low-salt (sodium) diet
  • if you drink alcohol or you are having withdrawal symptoms from stopping alcohol or benzodiazepines (eg, diazepam)
  • if you also take medicines for blood pressure, heart problems, kidney problems, or seizures
  • if you take any medicine that may increase the risk of seizures, irregular heartbeat, or kidney problems. Check with your doctor or pharmacist if you are unsure if any of your medicines may increase the risk of these problems

Some MEDICINES MAY INTERACT with sodium sulfate/potassium sulfate/magnesium sulfate solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Tricyclic antidepressants (eg, amitriptyline) because the risk of seizures may be increased
  • Angiotensin-converting enzyme (ACE) inhibitors (eg, lisinopril), angiotensin receptor blockers (eg, valsartan), diuretics (eg, furosemide, hydrochlorothiazide), nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), or other laxatives or bowel-cleansing products because they may increase the risk of sodium sulfate/potassium sulfate/magnesium sulfate solution's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if sodium sulfate/potassium sulfate/magnesium sulfate solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use sodium sulfate/ potassium sulfate/ magnesium sulfate solution:

Use sodium sulfate/potassium sulfate/magnesium sulfate solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Sodium sulfate/potassium sulfate/magnesium sulfate solution comes with an extra patient information sheet called a Medication Guide. It also comes with detailed instructions for use. Read them carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about sodium sulfate/potassium sulfate/magnesium sulfate solution.
  • Each bottle of sodium sulfate/potassium sulfate/magnesium sulfate solution must be mixed with water before drinking. Do NOT take sodium sulfate/potassium sulfate/magnesium sulfate solution without first mixing it with water. Doing so may increase the risk of nausea, vomiting, dehydration, and blood electrolyte problems. Be sure you understand how to take sodium sulfate/potassium sulfate/magnesium sulfate solution.
  • Sodium sulfate/potassium sulfate/magnesium sulfate solution is usually taken as 2 separate doses along with required amounts of water: 1 dose the evening before your procedure and 1 dose the morning (10 to 12 hours after the evening dose) of your procedure. Follow your doctor's instructions. Check with your doctor if you have questions or you are not sure how to take sodium sulfate/potassium sulfate/magnesium sulfate solution.
  • On the day before your procedure, a light breakfast may be eaten. After starting sodium sulfate/potassium sulfate/magnesium sulfate solution, do not eat any solid foods until your procedure is complete.
  • Starting the day before your procedure, you may have only clear liquids until the procedure is complete. Do not drink red or purple liquids, milk, or alcoholic beverages until your procedure is complete.
  • On the day of your procedure, you may only have clear liquids until your procedure is complete. Do not drink red or purple liquids, milk, or alcoholic beverages.
  • Drinking extra fluids before, during, and after you take sodium sulfate/potassium sulfate/magnesium sulfate solution is recommended. Check with your doctor for instructions.
  • You must finish drinking your second dose of sodium sulfate/potassium sulfate/magnesium sulfate solution and required water at least 2 hours before your procedure, unless your doctor tells you otherwise.
  • Medicines taken by mouth within 1 hour of starting each dose of sodium sulfate/potassium sulfate/magnesium sulfate solution may not be absorbed or be effective. Contact your doctor or pharmacist with any concerns you might have about taking your other medicines.
  • If you miss a dose of sodium sulfate/potassium sulfate/magnesium sulfate solution or are unable to complete the course of treatment, contact your doctor right away.

Ask your health care provider any questions you may have about how to use sodium sulfate/potassium sulfate/magnesium sulfate solution.

Important safety information:

  • The following are examples of clear liquids that you may drink the day before and the day of your procedure: water, strained fruit juices without pulp (including apple, orange, white grape, or white cranberry), limeade or lemonade (without pulp), coffee or tea (without creamer), chicken broth, gelatin desserts without added fruit or topping (no red or purple). Check with your doctor or pharmacist if you have questions about whether you may drink a certain liquid.
  • Contact your doctor right away if severe vomiting or diarrhea occurs, or if you become dehydrated after taking sodium sulfate/potassium sulfate/magnesium sulfate solution. These effects may lead to abnormal blood electrolyte levels, which may cause certain serious side effects (eg, irregular heartbeat, kidney problems, seizures). Discuss any questions or concerns with your doctor.
  • Do not use any other laxative products (eg, bisacodyl) or enemas while you are taking sodium sulfate/potassium sulfate/magnesium sulfate solution.
  • Lab tests, including blood electrolyte levels, heart function, and kidney function, may be performed while you use sodium sulfate/potassium sulfate/magnesium sulfate solution. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use sodium sulfate/potassium sulfate/magnesium sulfate solution with caution in the ELDERLY; they may be more sensitive to its effects, especially vomiting.
  • Sodium sulfate/potassium sulfate/magnesium sulfate solution should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking sodium sulfate/potassium sulfate/magnesium sulfate solution while you are pregnant. It is not known if sodium sulfate/potassium sulfate/magnesium sulfate solution is found in breast milk. If you are or will be breast-feeding while you take sodium sulfate/potassium sulfate/magnesium sulfate solution, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of sodium sulfate/ potassium sulfate/ magnesium sulfate solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Discomfort; feeling of being full or bloated; mild stomach pain, cramping, or discomfort; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); decreased urination; fainting; irregular heartbeat; seizures; severe or persistent nausea; severe or persistent stomach pain, bloating, cramping, or discomfort; symptoms of dehydration (eg, dizziness, headache, sluggishness, unusually dry mouth or eyes, weakness); vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of sodium sulfate/potassium sulfate/magnesium sulfate solution:

Store sodium sulfate/potassium sulfate/magnesium sulfate solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Keep sodium sulfate/potassium sulfate/magnesium sulfate solution out of the reach of children and away from pets.

General information:

  • If you have any questions about sodium sulfate/potassium sulfate/magnesium sulfate solution, please talk with your doctor, pharmacist, or other health care provider.
  • Sodium sulfate/potassium sulfate/magnesium sulfate solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take sodium sulfate/potassium sulfate/magnesium sulfate solution or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about sodium sulfate/potassium sulfate/magnesium sulfate solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to sodium sulfate/potassium sulfate/magnesium sulfate solution. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using sodium sulfate/potassium sulfate/magnesium sulfate solution.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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